There are currently 168 clinical trials in Columbia, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Carolina, Prisma Health Richland Hospital, GSK Investigational Site and Palmetto Health South Carolina Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Resistance Exercise and Creatine in Colorectal Cancer
NCT06420726
Recruiting
skeletal muscle mass and function, is prevalent in up to 60% of colorectal cancer patients. This condition arises from a combination of factors such as aging, inactivity, treatment side effects, malnutrition, tumor burden, and inflammation. Given this complexity, singular interventions may not be sufficient to address sarcopenia in this group. Creatine monohydrate, a compound vital for energy during exercise, has been extensively researched and proven safe and effective across various demograph... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Colorectal Cancer
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Palmetto Health, Columbia, South Carolina
Conditions: Homozygous Familial Hypercholesterolemia
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Healthy Kids Beyond the Bell: Investigating the Impact of After-School and Summer Programs
NCT05880901
Recruiting
Nearly one in five children are obese, and disparities in overweight and obesity between children from low- and middle-to-high-income households persist despite a multitude of school-based interventions. The structured days hypothesis posits that structure within a school day plays a protective role for children against obesogenic behaviors, and, ultimately, prevents the occurrence of excessive weight gain, thus, past school-based efforts are misplaced. This study will provide access to healthy... Read More
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
03/09/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Health Status Disparities, Pediatric Obesity, Ethnic Group, Socioeconomic Factors
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Determining the Optimal Amount of Structured Environments for Healthy Kids
NCT06158594
Recruiting
Studies show that virtually all increases in children's (5-12yrs) BMI occur during the summer, no matter children's' weight status (i.e., normal weight, overweight, or obese) at summer entry. Recent preliminary studies show that children engage in healthier behaviors on days that they attend summer day camps, and that BMI gain does not accelerate for these children. The proposed randomized dose-response study will identify the dose-response relationship between amount of summer programming and s... Read More
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
03/09/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Health Status Disparities, Pediatric Obesity, Ethnic Groups, Socioeconomic Factors
Register for Updates
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Huntington's Disease
Register for Updates
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
NCT05338697
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
Register for Updates
Developing a Trauma-focused Intervention for Older Adults Living With HIV
NCT05287230
Recruiting
Investigators are adapting the LIFT and REFLECT interventions for older adults living with HIV who have been exposed to childhood sexual abuse.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
12/01/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Trauma, Hiv, Aging
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Reducing Metabolic Dysregulation in Dyads
NCT06117241
Recruiting
This study is a 6-month randomized controlled trail of diet modification designed to reduce chronic inflammation and reverse metabolic dysfunction among obese individuals with one or more polyps found at a colonoscopy screening. We also will recruit an at least overweight partner, who lives in the same household. To be eligible, participants will be apparently disease-free, obese AAs or EAs who have self-identified a partner who is at least 9 years, with whom they live and who also is at least o... Read More
Gender:
ALL
Ages:
Between 9 years and 55 years
Trial Updated:
10/30/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Colorectal Cancer, Inflammation, Nutrition Related Cancer
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Mindful Walking Program for Older African Americans
NCT06085196
Recruiting
The goal of this clinical trial is to understand the beneficial role of mindful walking in sustaining cognitive health in African American older adults who have elevated risk of developing neuropsychological diseases. The main question it aims to answer is "Does a multi-session mindful walking intervention lead to promising signals of sustaining cognitive health in vulnerable AA older adults?" The researchers in this 2-arm randomized controlled trial will compare the mindful walking group with a... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/12/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Cognitive Function, Aging Well, Behavior, Health
Register for Updates
Young Breast Cancer Survivors Study
NCT05981716
Recruiting
Despite significant overall reductions in mortality rates for breast cancer over the past decade, both incidence and mortality rates have steadily climbed in adults diagnosed before age 50. This research project addresses factors associated with quality of life among and treatment response in early-age-at-onset breast cancer patients. The overall objective is collect information from early-onset breast cancer patients using an online questionnaire and examine factors related to cancer survival,... Read More
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
08/09/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Breast Cancer
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Connect Through PLAY: A Staff-based Physical Activity Intervention for Middle School Youth
NCT03732144
Recruiting
The overall goal of the Connect Through Positive Leisure Activities for Youth (PLAY) Project is to improve staff capacity for implementing effective physical activity (PA) programming within middle school after school programs serving high-risk youth. All components of the 'Connect' intervention (health promotion initiative, comprehensive training, and tailored physical activity curriculum) aim to support staff cohesion, motivation and efficacy in facilitating a PA context that supports youth so... Read More
Gender:
ALL
Ages:
Between 9 years and 16 years
Trial Updated:
05/08/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Physical Activity, Obesity Prevention
Register for Updates