There are currently 164 clinical trials in Columbia, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Carolina, Prisma Health Richland Hospital, GSK Investigational Site and Palmetto Health South Carolina Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Systemic Hypothermia in Acute Cervical Spinal Cord Injury
NCT02991690
Recruiting
This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33ºC) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord Injury (SCI).
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/16/2025
Locations: Prisma Health - University of South Carolina, Columbia, South Carolina
Conditions: Spinal Cord Injury, Acute
Register for Updates
A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)
NCT06952699
Recruiting
Narcolepsy without cataplexy or Narcolepsy Type 2 (NT2) is a lifelong condition that makes people very sleepy during the day, regardless of how much sleep they get at night. People with NT2 may fall asleep suddenly, have trouble staying awake during the day, or may not be able to sleep well at night. They may have difficulty thinking clearly, paying attention, or remembering things, during the day. These symptoms can make daily activities like driving, working, or caring for their families chall... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/15/2025
Locations: Takeda Site 2, Columbia, South Carolina
Conditions: Narcolepsy Type 2
Register for Updates
Electrical DN as an Adjunct to Eccentric Exercise, Stretching + MT for Achilles Tendinopathy
NCT03968614
Recruiting
The purpose of this research is to compare two different approaches for treating patients with achilles tendinopathy: eccentric exercise, stretching and manual therapy VS Electric dry needling, eccentric exercise, stretching and manual therapy. Physical therapists commonly use all of these techniques to treat achilles tendinopathy. This study is attempting to find out if one treatment strategy is more effective than the other.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: Prisma Health - Research PT Specialists, Columbia, South Carolina
Conditions: Achilles Tendinopathy
Register for Updates
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
NCT05370014
Recruiting
This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2 )(COVID-19) in African American (AA) adults with pre-existing chronic health conditions and their informal carepartners (IC). Socioeconomically disadvantaged, older, and Black/African American from rural regions are burdened with greater rates of chronic diseases such as diabetes, hypertension, chronic kidney disease, cardiovascular di... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: SARS- CoV-2, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease, Stroke
Register for Updates
Pentoxifylline in Diabetic Kidney Disease
NCT03625648
Recruiting
Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a study to bee conducted in 40 VA hospitals across the nation to determine definitively whether or not PTX can prevent worsening of kidney disease and delay death in patients with diabetic kidney disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC, Columbia, South Carolina
Conditions: Diabetic Kidney Disease
Register for Updates
Rested & Ready to Learn
NCT06882005
Recruiting
The goal of this pilot randomized controlled trial is to test the feasibility, acceptability, and preliminary signal of effect of a combined school- and home-based sleep promotion program for young children prior to the kindergarten transition.
Gender:
ALL
Ages:
Between 4 years and 6 years
Trial Updated:
05/09/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Sleep
Register for Updates
A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin
NCT05775523
Recruiting
The goal of this study is to further characterise the potential long-term safety risks of lonapegsomatropin in patients treated with lonapegsomatropin under real-world conditions in the post-marketing setting.
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
05/02/2025
Locations: Ascendis Investigational Site, Columbia, South Carolina
Conditions: Growth Hormone Deficiency
Register for Updates
A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA
NCT05820672
Recruiting
The goal of this study is to genrate evidence on long-term effectiveness and safety of SKYTROFA (lonapegsomatropin) in patients with growth hormone deficiency under routine clinical care
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
05/01/2025
Locations: Ascendis Investigational Site, Columbia, South Carolina
Conditions: Growth Hormone Deficiency
Register for Updates
Healthy Living After Knee Replacement
NCT05190666
Recruiting
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.
Gender:
ALL
Ages:
All
Trial Updated:
04/29/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Arthroplasty, Overweight and Obesity
Register for Updates
Dose Response of Exercise for Arthritis Management
NCT06880653
Recruiting
The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Arthritis, Rheumatoid Arthritis (RA), Gout, Fibromyalgia (FM), Osteoarthritis, Lupus Erythematosus, Systemic
Register for Updates
Investigating the Effects of the "GameDay Ready" Behavioral Weight Management Program for Black Men Living in the Rural South
NCT05970042
Recruiting
This pilot study investigates the effects of a newly developed 12-week weight management program called "GameDay Ready" (compared to a walking and general health education program) for decreasing body weight among Black men who live in the rural South. The researchers expect to see evidence of greater weight loss among participants randomized to receive the "GameDay Ready" program.
Gender:
MALE
Ages:
Between 25 years and 65 years
Trial Updated:
04/25/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Obesity
Register for Updates
Deliver-EE: Evaluating Effects of Meal Delivery
NCT05357261
Recruiting
This study will randomly assign 2,300 older adults on waiting lists at fourteen Meals on Wheels programs in Florida, Illinois, Maryland, Tennessee, Texas, North Carolina, South Carolina, and California into two groups who will receive: (a) daily delivery of meals, five days a week or (b) a shipment of 10 frozen meals, every two weeks. Researchers will examine participants' Medicare claims to understand if differences in healthcare utilization occur between the two groups within six months after... Read More
Gender:
ALL
Ages:
66 years and above
Trial Updated:
04/21/2025
Locations: Senior Resources Inc, Columbia, South Carolina
Conditions: Healthy
Register for Updates