There are currently 210 clinical trials in Knoxville, Tennessee looking for participants to engage in research studies. Trials are conducted at various facilities, including East Tennessee Children's Hospital, University of Tennessee Medical Center, Thompson Cancer Survival Center and University of Tennessee - Knoxville. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Acute Effects of Maternal Exercise and the Growth Restricted Pregnancy
Recruiting
Objectives / Specific Aims * The purpose of this study is to investigate the acute effects of a single bout of moderate intensity maternal exercise on fetal well-being in a pregnancy affected by fetal growth restriction. Fetal well-being will be measured by biophysical profile (BPP), non-stress test (NST) and umbilical artery dopplers. * The hypothesis is that a single bout of maternal exercise will not significantly alter fetal well-being or fetal status.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
09/08/2023
Locations: University of Tennessee Graduate School of Medicine, Knoxville, Tennessee
Conditions: Fetal Growth Retardation, Fetal Growth Complications, Placental Insufficiency
A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis
Recruiting
This study will investigate 99mTc-p5+14, an amyloid-reactive synthetic peptide, p5+14, radiolabeled with technetium-99m, as a radiotracer for detecting paamyloid deposits in patients with AL or ATTR-associated systemic amyloidosis, notably with cardiac involvement.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2023
Locations: University of Tennessee Graduate School of Medicine, Knoxville, Tennessee
Conditions: Systemic Amyloidosis
Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
Recruiting
In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
01/05/2023
Locations: Provision CARES Proton Therapy Center, Knoxville, Tennessee
Conditions: Pediatric Patients Treated With Radiation Therapy
CERENOVUS Neurothrombectomy Devices Registry
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: TNVI, Knoxville, Tennessee +1 locations
Conditions: Cerebral Stroke
Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
Recruiting
This study is being proposed to evaluate the use of moderate hypofractionated proton therapy in low and intermediate risk prostate cancer patients. Quality of life outcomes as well as gastrointestinal and genitourinary early and late toxicities will be analyzed and compared to conventional proton therapy regimens. It is thought that this regimen will produce comparable findings and would result in substantial health care cost savings, as well as, be more convenient for patients.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/03/2019
Locations: Provision Cares Proton Therapy Center Knoxville, Knoxville, Tennessee
Conditions: Prostate Cancer
Y90 Radioembolization Dose Delivery and Radiation Exposure Assessment
Recruiting
The objective of this study is to examine critical aspects of radiation exposure, dose delivery, and systemic yttrium-90 (Y90) exposure related to the infusion of Y90 microspheres for treatment of hepatocellular carcinoma (HCC) and other metastatic liver disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2018
Locations: University of Tennessee Medical Center, Knoxville, Tennessee
Conditions: Hepatocellular Carcinoma, Radiation Exposure