The state of Texas currently has 18 active clinical trials seeking participants for Autism research studies. These trials are conducted in various cities, including Houston, Dallas, San Antonio and Austin.
Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD
Recruiting
Autism spectrum disorder (ASD) consists of deficits in social, communication, and cognitive development, repetitive and stereotypic behaviors. Many ASD patients show notably high levels of irritability, including verbal and physical aggression, self injury, and/or property destruction. Autistic infants tend to avoid eye contact and show little interest in others. This study will assess how safe and effective cariprazine is in treating pediatric participants (5 to 17 years of age) with ASD. Adver... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
05/22/2024
Locations: BioBehavioral Research of Austin /ID# 255460, Austin, Texas +4 locations
Conditions: Autism Spectrum Disorder
Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder
Recruiting
6-week, randomized, double-blind, fixed-dose, placebo-controlled, parallel group study in children and adolescents (aged 5 to17 years) with autism spectrum disorder (ASD) with irritability, agitation, or self-injurious behaviors to study the efficacy and safety of pimavanserin
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
05/08/2024
Locations: Relaro Medical Trials, LLC, Dallas, Texas +2 locations
Conditions: Irritability Associated With Autism Spectrum Disorder
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
Recruiting
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day observation period. The study is being conducted in order to assess safety and tolerability of the probiotic (BB-12 with LGG) at 2 different doses of BB-12 with LGG. Identifying effects on behaviors in healthy children with ASD using SRS-2 and ABC, GI symptoms using GI symptom... Read More
Gender:
All
Ages:
Between 4 years and 16 years
Trial Updated:
05/06/2024
Locations: UTHealth, Houston, Texas
Conditions: Autism Spectrum Disorder, Gastrointestinal Symptoms
Extension Study of Pimavanserin in Irritability Associated With Autism Spectrum Disorder
Recruiting
52-week, open-label extension study of double-blind study ACP-103-069 to determine the long-term safety and tolerability of pimavanserin for the treatment of irritability associated with ASD in children and adolescents (aged 5 to 17 years). ACP-103-069 is a 6-week, randomized, double-blind, fixed-dose, placebo controlled, parallel group study of pimavanserin in children and adolescents with irritability associated with autism spectrum disorder (ASD).
Gender:
All
Ages:
Between 5 years and 18 years
Trial Updated:
05/02/2024
Locations: Relaro Medical Trials, LLC, Dallas, Texas +1 locations
Conditions: Irritability Associated With Autism Spectrum Disorder
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
Recruiting
ML-004-002 is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study that will enroll approximately 150 adolescent and adult subjects with ASD. The primary objective is to evaluate the efficacy of ML-004 compared with placebo in the improvement of social communication deficits in subjects with ASD.
Gender:
All
Ages:
Between 12 years and 45 years
Trial Updated:
04/30/2024
Locations: Red Oak Psychiatry Associates, PA, Houston, Texas +1 locations
Conditions: Autism Spectrum Disorder
Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder
Recruiting
The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish the benefit-risk profile of long-term treatment in this population.
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
03/04/2024
Locations: BioBehavioral Research of Austin /ID# 236479, Austin, Texas +3 locations
Conditions: Schizophrenia, Bipolar I Disorder, Autism Spectrum Disorder (ASD)
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
Recruiting
To determine sufficient number of biological and clinical markers to identify subgroups of potential best responders to a specific medication
Gender:
All
Ages:
Between 12 years and 65 years
Trial Updated:
03/01/2024
Locations: Red Oak Psychiatry Associates, Houston, Texas
Conditions: Autism Spectrum Disorder
Developing a Culturally Adapted Intervention for Latino Youth Transitioning to Adulthood
Recruiting
The purpose of this study is to evaluate the acceptability, feasibility (e.g., satisfaction, completion rate, barriers to recruitment, treatment fidelity) of the culturally refined Launching! to Adulthood (¡Iniciando! la Adultez) program, to test for a preliminary signal of effect between baseline and post-treatment for the Launching! to Adulthood (¡Iniciando! la Adultez) program and to identify preliminary neural mechanisms of action, including biomarkers of brain structure and connectivity, in... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
02/28/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Recruiting
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting. The purpose of this study is to determine the feasibility of implementing this treatment in community care centers.
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
02/13/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder, Social Anxiety Disorder of Childhood
Sibling-Mediated Intervention on Literacy and Reciprocity for Children With Autism
Recruiting
Given the increasing prevalence of autism spectrum disorder (ASD), estimated to be 1 in 68 in the United States alone, ASD has become one of the fastest-growing pediatric concerns. The deficits of children with ASD range across social communication and academic skills. One of the effective interventions that have been used commonly for ASD is the model-lead-test, which includes modeling, prompting children to practice target skills together, and providing children with affirmative feedback or er... Read More
Gender:
All
Ages:
Between 5 years and 11 years
Trial Updated:
02/12/2024
Locations: Children's Autism Center, Round Rock, Texas
Conditions: Autism Spectrum Disorder
Optimizing Intervention Options for Toddlers With Early Social Communication Delays
Recruiting
Improving social communication outcomes for toddler siblings of children with autism, who are at high risk for multiple language and communication deficits beyond autism, has important public health implications. The proposed study is a pilot sequential multiple random assignment trial of 44 high-risk siblings that examines the feasibility, acceptability, and preliminary effects of an adaptive intervention for social communication. Evaluating effective parent-mediated communication support strat... Read More
Gender:
All
Ages:
Between 11 months and 18 months
Trial Updated:
01/10/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Autism Sibling
Implementation of the Parents Taking Action in Paraguay
Recruiting
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism in Paraguay. The following research questions will be addressed: Research Question #1: What is the feasibility and acceptability of the intervention? Research Question #2: Do participants improve between pre and post-test on outcome measures? Parents will receive 10 wee... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
01/04/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Depression, Autism