The state of Texas currently has 53 active clinical trials seeking participants for COVID19 research studies. These trials are conducted in various cities, including Houston, Dallas, San Antonio and Austin.
COVID-19 Outcome Prediction Algorithm
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
Evaluation of Aerosol in a Dental Clinic
Recruiting
The purpose of this study is to evaluate the effectiveness of external evacuation units and mouth rinses during aerosol generating procedures in a dental clinic and to determine the risk level to the dental practitioners during aerosol generating procedures.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Covid19
Immuno-bridging and Broadening Study of a Whole, Inactivated COVID-19 Vaccine BBV152 in Healthy Adults
Recruiting
A randomized, observer-blind, placebo-controlled immuno-bridging, and broadening study to demonstrate the equivalence of the immune response between participants enrolled in Phase 3 efficacy trial in India and demographically diverse healthy adult participants in the US which matched in age and vaccine formulation setting to whom those efficacy results are extrapolated; and to assess the broadening of the BBV152 in participants who previously received two shots of messenger ribonucleic acid (mRN... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2023
Locations: PRX Research, Dallas, Texas +1 locations
Conditions: COVID-19
A Phase 1/2 Study to Assess the Safety and Immunogenicity of JCXH-221, an mRNA-based Broadly Protective COVID-19 Vaccine
Recruiting
The goal of this clinical trial is to learn about, test, and compare JCXH-221 in healthy volunteers. The main aims to answer are: To assess the safety and tolerability of the JCXH-221 vaccine in healthy adult subjects To identify an optimal dose for the JCXH-221 vaccine in healthy adult subjects To assess the humoral immunogenicity of the JCXH-221 vaccine in healthy adult subjects To characterize the cellular immunogenicity of the JCXH-221 vaccine in healthy adult subjects Participants for Pha... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/16/2023
Locations: Velocity Clinical Research, Cedar Park, Texas
Conditions: COVID-19, Infectious Disease
Electrical Stimulation for Post Acute COVID-19 Syndrome
Recruiting
The purpose of the pilot study is to examine acceptability and proof of concept effectiveness of a wireless TENS technology to address PACS associated FM. Sample size (n=40) is convenient and designed to explore acceptability and feasibility. Eligible participants will be screened at the BCM Post-COVID-19 Clinic for inclusion criteria. Participants, who satisfy the inclusion and exclusion criteria and sign the informed consent form will be randomly assigned with ratio of 1:1 into two groups. One... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/17/2023
Locations: Baylor College of Medicine, Houston, Texas +1 locations
Conditions: COVID-19, Muscle Weakness, Muscle Pain, Fatigue
Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia
Recruiting
This study is an open-label, single-arm study to evaluate the safety and efficacy of Astrostem-V, allogenic adipose tissue derived mesenchymal stem cells (AdMSC), in patients with COVID-19 pneumonia. After each subject completes 12-Weeks visit (Visit 12) and the data management team confirms all individual data have no issue, the individual database will be locked and the blinding will be open for the statistical analysis.
Gender:
All
Ages:
Between 19 years and 80 years
Trial Updated:
01/09/2023
Locations: Epic Medical Research, Dallas, Texas
Conditions: Covid19 Pneumonia
A Study to Evaluate EDP-235 in Non-hospitalized Adults With COVID-19
Recruiting
Study of EDP-235 in Non-hospitalized Adults with Mild or Moderate COVID-19.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
12/06/2022
Locations: SMS Clinical Research, LLC, Mesquite, Texas +1 locations
Conditions: COVID-19
Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)
Recruiting
This clinical pharmacology study will evaluate the relative bioavailability, safety, and tolerability of two different concentrations of sotrovimab injections administered at different injection sites in male or female healthy participants aged 18 to 65 years. The study will be conducted in three parts (Part A, an optional Part B and Part C).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/02/2022
Locations: Investigative Site, Austin, Texas +1 locations
Conditions: Covid19
Evaluation of the Clinical Impact of Corticosteroid Duration on SARS-CoV-2 (COVID-19 WHO)
Recruiting
The purpose of this project is to evaluate the clinical impact of the use of glucocorticoids beyond 10 days for patients with critical COVID-19 at MDMC.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/21/2022
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Covid 19
Study to Reinforce Immunity (STRI) Phase 2 Clinical Trial
Recruiting
Protocol STRI12 - Study to Reinforce Immunity (STRI) - A Phase 2 Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of STRI Formula in Non-Hospitalized Participants with COVID-19 (the Study)
Gender:
All
Ages:
18 years and above
Trial Updated:
09/08/2022
Locations: Dorisca Research Consulting, Houston, Texas
Conditions: Covid19
Change in Antibody Levels Following SARS-CoV-2 (Covid-19) Vaccinations
Recruiting
Limited information is available regarding the effects of various factors that may influence the duration and effectiveness of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) vaccinations. This virus causes Covid-19. Such factors include age, disease states, general immunocompetence, and use of various drugs. The results of this study by Southlake Diagnostics Inc. will provide base-line antibody (IgG and total) data regarding the extent to which the results from this test can be int... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
08/26/2022
Locations: Southlake Diagnostics, Inc., Southlake, Texas
Conditions: Covid-19, Subjects Vaccinated Against Covid-19
Non-invasive Characterization of Systemic Microvascular Reactivity by Near-infrared Diffuse Optical Spectroscopy in COVID-19 Patients
Recruiting
The purpose of this study is to characterize microvascular reactivity on the forearm muscle using non-invasive near-infrared spectroscopy in critically ill COVID-19 patients, and to correlate its alterations with 28-day mortality in ICU COVID-19 patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/27/2022
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: COVID-19, Endothelial Function