There are currently 1470 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Exploration of Central Venous Catheter Protective Devices in the Pediatric Population: A Mixed Methods Study
NCT05415449
Recruiting
1. to determine the feasibility of utilizing a wearable device 2. to prospectively measure and evaluate parent and nurse satisfaction with the protective wearable device. This is a sequential, convergent mixed methods study design in which qualitative interview data will be collected first followed by quantitative data. Scheme and Outcomes: Identify eligible patients--Informed Consent--Provide education and two protective wearable device--Demographic data (electronic health record)--Interview... Read More
Gender:
ALL
Ages:
Between 0 years and 12 years
Trial Updated:
11/04/2024
Locations: Children's Health, Dallas, Texas
Conditions: Central Line
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MASA Valve Early Feasibility Study
NCT05452720
Recruiting
The MASA Valve Early Feasibility Study (MVEFS) multi-site interventional clinical trial within the United States of America with each center following a common protocol.The objective of the trial is to evaluate the safety and probable benefit of MASA Valve in the indicated subset of patients requiring Right Ventricular Outflow Tract Reconstruction (RVOTR). As an early feasibility study, the purpose is determine the feasibility of success of the device in order to gather early data towards a futu... Read More
Gender:
ALL
Ages:
Between 0 years and 22 years
Trial Updated:
11/04/2024
Locations: Childrens Medical Center Dallas, Dallas, Texas
Conditions: Tetrology of Fallot, Pulmonary Stenosis, Truncus Arteriosus, Transposition of Great Vessels, Pulmonary Atresia, Ross Procedure
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A Study of DCR-STAT3 in Adults With Solid Tumors
NCT06098651
Recruiting
This is a sequential, ascending-dose, multicenter study conducted in patients with refractory solid tumors designed to evaluate the safety, tolerability, and pharmacokinetics of DCR-STAT3.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Next Oncology, Dallas, Texas
Conditions: Solid Tumor, Adult, Refractory Tumor
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ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05682443
Recruiting
In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The study is open-label, randomized with active control, multi-center study.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: University of Texas Southwestern Medical Center - 1604, Dallas, Texas
Conditions: Metastatic Castration-resistant Prostate Cancer
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[18F]PT2385 PET/CT in Patients with Renal Cell Carcinoma
NCT04989959
Recruiting
This is an exploratory study to assess \[18F\]PT2385 Positron Emission Tomography/Computed Tomography (PET/CT) in patients with renal cell carcinoma (RCC). This is an open-label, nontherapeutic trial. The main objective is to correlate hypoxia-inducible factor-2alpha (HIF2α) levels as determined by an investigational \[18F\]PT2385 PET/CT scan with the levels on subsequently obtained tissue by HIF2α immunohistochemistry (IHC). There will be three cohorts. The first pre-surgical cohort will have \... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
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Hyperinflation Respiratory Therapies in Cardiac Surgery Patients
NCT04164173
Recruiting
The purpose of this prospective randomized clinical trial is to evaluate three different types of hyperinflation respiratory therapies, Intermittent Positive Pressure Breathing (IPPB), Intermittent positive end expiratory pressure (EzPAP), Metaneb. Investigators will examine which hyperinflation therapy provides better lung expansion and may improve lung recovery after surgery.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/28/2024
Locations: UT Southwestern Clements University Hospital, Dallas, Texas
Conditions: Pulmonary Disease, Postoperative Complications
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Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
NCT06444269
Recruiting
1. Efficacy of PULSAR preoperative radiation 2. Evaluate potential of microbubble CEUS as an alternative to operative SLNBx 3. Evaluate potential of OA to evaluate treatment response of pre-operative radiation on the tumor
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/28/2024
Locations: UT Southwestern Medical Center-Dallas, Dallas, Texas
Conditions: Breast Cancer
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Study of ART6043 in Advanced/Metastatic Solid Tumors Patients
NCT05898399
Recruiting
This interventional study will evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ART6043 as monotherapy or in combination with Olaparib or Niraparib.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Mary Crowley Cancer Center - Clinic, Dallas, Texas
Conditions: Advanced Solid Tumor, Metastatic Solid Tumor
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A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
NCT04673942
Recruiting
AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and tolerable. The next step is to find out if AdAPT-001 if efficacious with or without a checkpoint inhibitor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Solid Tumor, Adult, Cancer, Neoplasms, Sarcoma, Sarcoma,Soft Tissue, Chondrosarcoma
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Treating Mild Traumatic Brain Injury with High Definition Transcranial Direct Current Stimulation
NCT04869059
Recruiting
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve verbal retrieval in military veteran participants with histories of traumatic brain injuries. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/23/2024
Locations: The University of Texas at Dallas, Dallas, Texas
Conditions: Traumatic Brain Injury
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Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
NCT05442957
Recruiting
In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be randomized to BRIGHT (a brief video tele-cognitive behavioral therapy intervention) or Attention Control (AC, a manualized tele-supportive care intervention that controls for professional attention, dose, delivery method, and common factors). HNC survivors will complete IMAGE-HN (a validated patient-reported outcome measure \[PROM\] of HNC-rel... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/21/2024
Locations: University of Texas Southwestern, Dallas, Texas
Conditions: Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship, Psychosocial Impairment, Mental Health Issue
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Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
NCT05766813
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Society (UKPDS) Brain Bank diagnostic criteria, who are experiencing wearing off symptoms and levodopa-induced dyskinesia.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/21/2024
Locations: Clinical Site, Dallas, Texas
Conditions: Parkinson Disease
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