There are currently 1500 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study of ALTO-300 in MDD
NCT05922878
Recruiting
The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/05/2024
Locations: Site 102, Dallas, Texas
Conditions: Major Depressive Disorder
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Suicide Treatment Alternatives for Teens
NCT04089254
Recruiting
Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.
Gender:
ALL
Ages:
Between 12 years and 18 years
Trial Updated:
07/03/2024
Locations: UT Southwestern Medical Center/Children's Health, Dallas, Texas
Conditions: Suicidal Ideation
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Tofacitinib in Recurrent GBM Patients
NCT05326464
Recruiting
The purpose of this study is to examine the effects of Tofacitinib in patients with recurrent Glioblastoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Glioblastoma
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Prediction of Neoadjuvant Chemotherapy Response Using Contrast-Enhanced Ultrasound in Patients With Locally Advanced Breast Cancer
NCT04715958
Recruiting
This phase II/III trial studies if contrast-enhanced ultrasounds using a contrast dye, perflutren lipid microspheres (Definity), can predict the response to chemotherapy by estimating the pressure in the cancer in patients with breast cancer that has spread to nearby tissues and lymph nodes (locally advanced). The efficacy of cancer therapy is affected by the pressure in the cancer. Definity is a contrast dye used to create better images during ultrasounds. The purpose of this trial is to determ... Read More
Gender:
FEMALE
Ages:
21 years and above
Trial Updated:
07/03/2024
Locations: UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Conditions: Anatomic Stage III Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma
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Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
NCT03391778
Recruiting
This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.
Gender:
ALL
Ages:
All
Trial Updated:
07/02/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Neoplasms
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Increasing HIV/STI Home Testing Via a Digital Intervention Among Black Women
NCT05390541
Recruiting
The proposed intervention is a web-based intervention guided by theoretical components to increase HIV home testing among Black women at risk for HIV and sexually transmitted infections (STIs) in a HIV hotspot in the South. The intervention will promote using the home test, linkage to care, and linkage to pre-exposure prophylaxis (PrEP) evaluation. The intervention has the potential to be implemented on a large scale and tailored based on location and population to increase testing, treatment, a... Read More
Gender:
FEMALE
Ages:
Between 15 years and 59 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins Bloomberg School of Public Health, Dallas, Texas
Conditions: Hiv, Sexually Transmitted Diseases, Economic Problems
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Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
NCT02201992
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: Parkland Memorial Hospital, Dallas, Texas +1 locations
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
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A Phase 2 Study of RTA 901 (BIIB143) in Participants With Diabetic Peripheral Neuropathic Pain (CYPRESS)
NCT05895552
Recruiting
This is a 2-part, randomized, placebo-controlled, double-blind, Phase 2 study to evaluate the safety, tolerability, efficacy, and pharmacokinetics (PK) of RTA 901 in qualified participants with Diabetic Peripheral Neuropathic Pain (DPNP). Each study part will be randomized into 3 treatment arms; 2 different doses of RTA 901 and RTA 901-maching placebo. The doses of RTA 901 in Part 2 will be selected based on the Exposure-Response (E-R) analyses of data from Part 1. A total of 384 participants wi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/28/2024
Locations: Zenos Clinical Research, Dallas, Texas
Conditions: Diabetic Peripheral Neuropathic Pain
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Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6
NCT04830124
Recruiting
This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanoma
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: UT Southwestern Medical Center of Dallas, Dallas, Texas
Conditions: Cutaneous Melanoma, Mucosal Melanoma
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Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression
NCT03952962
Recruiting
Treatment resistant depression remains a major problem for individuals and society. Surgical procedures may provide relief for some of these patients. The most frequently considered surgical approach is deep brain stimulation (DBS) of a part of the brain called the subcallosal cingulate region. However, the effectiveness and safety is not well established. The investigators will use a novel approach using advanced imaging technique (magnetic resonance tractography) to evaluate the feasibility an... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
06/26/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Treatment Resistant Depression, Undergoing Deep Brain Stimulation (DBS) Surgery
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The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers.
NCT05371756
Recruiting
The purpose of the Texas Immuno-Oncology Biorepository (TIOB) is to collect and store well-defined and well-annotated serial biospecimens of tissue, blood, urine and stool in a longitudinal manner from cancer patients who are receiving either standard of care surgical interventions and or FDA approved immunotherapeutics across the largest not-for-profit health system in Texas. Comprehensive clinical and radiological data from a diverse population of patients with different racial, social and eth... Read More
Gender:
ALL
Ages:
All
Trial Updated:
06/26/2024
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Cancer
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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: Texas Oncology - Methodist Dallas Cancer Center, Dallas, Texas +2 locations
Conditions: Breast Cancer
Register for Updates