There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study of LOXO-435 in Participants With Cancer With a Change in a Gene Called FGFR3
Recruiting
The main purpose of this study is to learn more about the safety, side effects, and effectiveness of LOXO-435. LOXO-435 may be used to treat cancer of the cells that line the urinary system and other solid tumor cancers that have a change in a particular gene (known as the FGFR3 gene). Participation could last up to 30 months (2.5 years) and possibly longer if the disease does not get worse.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Urinary Bladder Neoplasms, Neoplasm Metastasis, Ureteral Neoplasms
Metabolic Biomarkers in Thoracic Cancers
Recruiting
The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slight... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Lung Cancer
EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
Recruiting
Proton pump inhibitors (PPIs) are widely used for the control of gastric ulcer-gastritis, erosive esophagitis (gastroesophageal reflux disease), peptic ulcer disease (duodenal ulcer), and heartburn. Despite their efficacy, their use has been implicated in possibly causing fragility fractures (osteoporosis), hypomagnesemia (magnesium deficiency) and increased risk of chronic kidney disease (CKD). The current trial represents the investigators ongoing effort to discern whether these complications... Read More
Gender:
All
Ages:
Between 21 years and 99 years
Trial Updated:
05/21/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas +1 locations
Conditions: Osteoporosis, Hypomagnesemia
Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement
Recruiting
This is an open-label, multinational, randomized Phase 2 study confirming the clinical benefit of 20 mg futibatinib and evaluating the safety and efficacy of 16 mg futibatinib in previously treated CCA harboring FGFR2 gene fusions and other rearrangements.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: The Liver Institute at Methodist Dallas Medical Center, Dallas, Texas
Conditions: Advanced Cholangiocarcinoma, FGFR2 Fusions, Gene Rearrangement
The PEERLESS II Study
Recruiting
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Parkland Hospital, Dallas, Texas
Conditions: Pulmonary Embolism
Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder
Recruiting
Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of I... Read More
Gender:
Female
Ages:
Between 15 years and 30 years
Trial Updated:
05/21/2024
Locations: UT Southwestern Multispecialty Psychiatry Clinic, Dallas, Texas
Conditions: Anorexia Nervosa
Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome
Recruiting
This phase II trial studies the effect of venetoclax and azacitidine in treating patients with therapy related or secondary myelodysplastic syndrome. Venetoclax may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving venetoclax in combination with azacit... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Secondary Myelodysplastic Syndrome, Therapy-Related Myelodysplastic Syndrome
Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma
Recruiting
The goal of this study is to assess and compare the effectiveness of fluticasone furoate/umeclidinium bromide/vilanterol trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/21/2024
Locations: GSK Investigational Site, Dallas, Texas
Conditions: Asthma
Tempus Priority Study: A Pan-tumor Observational Study
Recruiting
Observational study that will be collecting clinical and molecular health information from cancer patients who have received comprehensive genomic profiling and meet the specific eligibility criteria outlined for each cohort with the goal of conducting research to advance cancer care and create a dataset that furthers cancer research.
Gender:
All
Ages:
All
Trial Updated:
05/21/2024
Locations: UT Southwestern, Dallas, Texas
Conditions: Breast Cancer, Prostate Cancer, Bladder Cancer, Lung Cancer, Brain Cancer, Pancreatic Cancer, Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer, Cancer of Liver, Cancer of Colon, Cancer of Head and Neck, Cancer of Stomach, Cancer of Gastrointestinal Tract, Cancer of Rectum, Cancer of Esophagus, Cancer of Skin, Cancer of Cervix, Cancer of Kidney, Cancer of Larynx, Cancer of Endometrium, Cancer of the Bile Duct, Cancer of Vulva, Cancer of Bone and Connective Tissue, Leukemia, Lymphoma, Spinal Cord Cancer
Early Robotic Gait Training After Stroke
Recruiting
The ERA Stroke project will compare the effects of robotic gait training (RGT) and usual care (UC) gait training in patients in the subacute phase of stroke recovery undergoing inpatient rehabilitation at the Baylor Scott & White Institute for Rehabilitation (BSWIR).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/21/2024
Locations: Baylor Scott & White Institute for Rehabilitation, Dallas, Texas
Conditions: Stroke
remedē System Therapy Study
Recruiting
The purpose of this non-randomized post market study is to collect clinical data on the safety and effectiveness of the remedē System in a real-world setting.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Baylor Scott and White - Dallas, Dallas, Texas
Conditions: Central Sleep Apnea
A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery
Recruiting
This study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called a "study drug" or called "study drugs" when combined) compared with an approved medication called pembrolizumab. The objective of this study is to see if the combination of fianlimab and cemiplimab is an effective treatment compared to pembrolizumab in patients that have had melanoma removal surgery but are still at hi... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
05/21/2024
Locations: The University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Melanoma