There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study Of ATRN-119 In Patients With Advanced Solid Tumors
NCT04905914
Recruiting
The purpose of this study is to assess the safety and effectiveness of ATRN-119 through the performance of a Phase 1/2a, open-label, safety, PK, and preliminary efficacy study of oral ATRN-119 in patients with advanced solid tumors.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/06/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Advanced Solid Tumor
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The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
NCT05762302
Recruiting
This is a Prospective, multi-center study enrolling adults subjects presented to the ED/Urgent care, with symptoms consistent with lower respiratory infection (LRTI). The reason of this study is to demonstrate the MeMed BV can help clinicians make decisions about using antibiotics in patients with lower respiratory track infections and see how it would impact clinical outcomes, antibiotics use, hospitalizations, ED clinicians find ways to improve health and medical care.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/06/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Lower Respiratory Tract Infection
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Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
NCT03012529
Recruiting
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to o... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
05/06/2024
Locations: VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas
Conditions: Osteomyelitis, Diabetes, Amputation
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An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice
NCT05369832
Recruiting
The purpose of this study is to explore the safety, efficacy, effects on quality of life (QOL), and biomarker response of ozanimod in participants with moderate to severely active ulcerative colitis (UC) in clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Baylor Research Institute, Dallas, Texas
Conditions: Colitis, Ulcerative
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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
NCT05926765
Recruiting
This study will assess the efficacy and safety of bilateral intra-parotid administration of AAV2-hAQP1 in adults with Grade 2 or Grade 3 radiation-induced late xerostomia.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
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Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants
NCT00992303
Recruiting
RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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Vardenafil Inhaled for Pulmonary Arterial Hypertension PRN Phase 2B Study
NCT04266197
Recruiting
The objectives of this study are to evaluate the safety of RT234 and the effects of RT234 on exercise capacity as assessed by Cardiopulmonary Exercise Testing (CPET) and six minute walk testing (6MWT) as well as exertional symptoms in patients with pulmonary arterial hypertension (PAH).
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/06/2024
Locations: Baylor Scott and White Institute, Dallas, Texas
Conditions: Pulmonary Arterial Hypertension
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Metabolic Remodeling in Pulmonary Arterial Hypertension (PAH)
NCT04968210
Recruiting
Pulmonary arterial hypertension (PAH) is a progressive disease in which clinically relevant symptoms present a few years after the onset in rise of pulmonary arterial pressure. Increased PA pressure presents an overload on the right ventricle (RV), with RV failure being a common cause of mortality in PAH. Current therapeutic targets help reduce vascular resistance and RV afterload, however, RV dysfunction may continue to progress. Therefore, the reason for RV failure in PAH cannot be contributed... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/06/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Pulmonary Arterial Hypertension
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Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy
NCT06080503
Recruiting
To compare the acute tolerance of highly conformal hypofractionated versus conventional radiotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Laryngeal Carcinoma
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Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
NCT03104517
Recruiting
This study evaluates the efficacy and safety of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR; generic name: iltamiocel) compared to a placebo in the reduction of stress incontinence episode frequency in adult female patients with post-surgical persistent or recurrent stress urinary incontinence (SUI). Half of the participants will receive AMDC-USR (injections with cells) and the other half will receive placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Urology Clinics of North Texas, PLLC, Dallas, Texas +1 locations
Conditions: Stress Urinary Incontinence
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Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets
NCT05046184
Recruiting
The study is investigating dysfunctions in neurocircuitry in regards to irritability with healthy controls (HC) and individuals with Major Depressive Disorder (MDD) by performing MRIs. The MDD group will also be randomized to receive ketamine or midazolam to investigate changes post-treatment in neurocircuitry with regards to irritability.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/03/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Major Depressive Disorder, Healthy Controls
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A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors
NCT05572684
Recruiting
This is an open-label, non-randomized, Phase 1b/2 study to determine the safety and tolerability of NC410 when combined with a standard dose of pembrolizumab. This study will also assess the clinical benefit of combination therapy in participants with advanced unresectable and/or metastatic ICI refractory solid tumors OR ICI naïve MSS/MSI-low solid tumors
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: UT Southwestern Medical Center, Dallas, Texas +1 locations
Conditions: Advanced or Metastatic Solid Tumors, Microsatellite Instability Low, Microsatellite Instability High, Microsatellite Stable, Ovarian Cancer, Gastric Cancer, Colo-rectal Cancer, Esophageal Cancer, Endometrial Cancer, Head Neck Cancer, Cervical Cancer, Lung Cancer
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