There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection
NCT05897541
Recruiting
The purpose of this study is to measure the proportion of participants who are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (positive reverse transcription polymerase chain reaction [RT-PCR] test) and have coronavirus disease 2019 (COVID-19) symptom(s) with S-217622 tablets compared with placebo tablets in participants who are household contacts of an individual with symptomatic COVID-19.
Gender:
All
Ages:
All
Trial Updated:
03/30/2024
Locations: Alina Clinical Trials, LLC, Dallas, Texas +1 locations
Conditions: SARS-CoV-2 Infection
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ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
NCT05172960
Recruiting
The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects with symptomatic, severe, calcific aortic stenosis (AS).
Gender:
All
Ages:
All
Trial Updated:
03/29/2024
Locations: Baylor Heart and Vascular Hospital, Dallas, Texas +1 locations
Conditions: Aortic Stenosis, Severe
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: University of Texas-Southwestern Medical Center Dallas, Dallas, Texas
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
NCT05126758
Recruiting
HOPE-3 is a two cohort, Phase 3, multi-center, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of a cell therapy called CAP-1002 in study participants with Duchenne muscular dystrophy (DMD) and impaired skeletal muscle function. Non-ambulatory and ambulatory boys and young men who meet eligibility criteria will be randomly assigned to receive either CAP-1002 or placebo every 3 months for a total of 4 doses during the first 12-months of the study. Al... Read More
Gender:
Male
Ages:
10 years and above
Trial Updated:
03/29/2024
Locations: Children's Health Specialty Care Pavilion, Dallas, Texas
Conditions: Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases, Neuromuscular Diseases, Genetic Diseases, X-Linked, Genetic Diseases, Inborn, Nervous System Diseases
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A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease
NCT04020055
Recruiting
An Open-label Study to Evaluate the Safety and Pharmacokinetics of Migalastat HCl in Subjects with Fabry Disease and Amenable GLA Variants and Severe Renal Impairment (SRI) or End Stage Renal Disease (ESRD)
Gender:
All
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: Renal Disease Research Institute, Dallas, Texas
Conditions: Fabry Disease
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Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)
NCT03067467
Recruiting
This is a non-randomized, purely observational, feasibility study to detect metabolic changes in patients with brain malignancy using a novel hyperpolarized [1-13C]pyruvate MRSI.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/28/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Brain Tumor Adult
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TrEatment Approach in the Multimodal Era Registry
NCT05629052
Recruiting
The goal of this observational patient registry is to learn how expert centers treat patients with chronic thromboembolic pulmonary hypertension (CTEPH). CTEPH is a condition in which blood clots block the blood vessels in the lungs. There are currently three treatment options for patients with CTEPH: surgery to remove blood clots from large vessels in the lungs (pulmonary endarterectomy (PEA)) the use of a small balloon to unblock smaller blood vessels (balloon pulmonary angioplasty (BPA)) dru... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: UT Southwestern, Dallas, Texas
Conditions: Chronic Thromboembolic Pulmonary Hypertension, CTEPH
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A Study of TCD601 in the Induction of Tolerance in de Novo Renal Transplantation (PERSPECTIVE)
NCT04803058
Recruiting
The purpose of this study is to evaluate if TCD601 can induce allogeneic tolerance in de novo living donor renal transplant recipients
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
03/28/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Kidney Transplantation
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A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas
NCT05279300
Recruiting
This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug CS5001 in patients with advanced hematological and solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: BUMC - Mary Crowley Cancer Research Centers (MCCRC), Dallas, Texas
Conditions: Advanced Solid Tumor, Advanced Lymphoma
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Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
NCT04331769
Recruiting
Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction (HFrEF).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2024
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
Register for Updates
Intacs Prescription Inserts for Keratoconus Patients
NCT02138669
Recruiting
The US food and Drug Administration (FDA) originally approved INTACS prescription inserts in April 1999 for the correction of low levels of nearsightedness (-1.00 to -3.00 diopters). Additional clinical data have shown that INTACS are safe for the treatment of keratoconus, in July 2004, FDA approved INTACS inserts for the treatment of keratoconus as a Humanitarian Use Device (FDA approval letter attached). The statute and the implementing regulation of FDA (21 CFR 814.124 (aj) require IRB review... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2024
Locations: UTSW Medical Center at Dallas, Dallas, Texas
Conditions: Keratoconus
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BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
NCT05003843
Recruiting
The objective of this study is to demonstrate the safety and efficacy of the Indigo Aspiration system for percutaneous mechanical thrombectomy in a population presenting with obstruction due to deep vein thrombosis (DVT) who are eligible for treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2024
Locations: BUMC - Dallas (Scott & White), Dallas, Texas
Conditions: Deep Vein Thrombosis, DVT
Register for Updates