There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
Recruiting
The goal of this clinical research study is to evaluate a method involving a blood test, called CA-125, that may be helpful in the early detection of ovarian cancer in women who are at low risk.
Gender:
Female
Ages:
Between 50 years and 74 years
Trial Updated:
03/07/2024
Locations: University of Texas (UT) Southwestern Medical Center, Dallas, Texas
Conditions: Ovarian Cancer
Study to Assess the Safety and Efficacy of OCU410ST for Stargardt Disease
Recruiting
This is a Phase 1/2 Study to Assess the Safety and Efficacy of OCU410ST for Stargardt Disease. This is a multicenter study, which will be conducted in two phases and will enroll up to a total of 42 subjects.
Gender:
All
Ages:
Between 6 years and 65 years
Trial Updated:
03/07/2024
Locations: Retina Foundation of the Southwest, Dallas, Texas
Conditions: Stargardt Disease
MASA Valve Early Feasibility Study
Recruiting
The MASA Valve Early Feasibility Study (MVEFS) multi-site interventional clinical trial within the United States of America with each center following a common protocol.The objective of the trial is to evaluate the safety and probable benefit of MASA Valve in the indicated subset of patients requiring Right Ventricular Outflow Tract Reconstruction (RVOTR). As an early feasibility study, the purpose is determine the feasibility of success of the device in order to gather early data towards a futu... Read More
Gender:
All
Ages:
Between 0 years and 22 years
Trial Updated:
03/07/2024
Locations: Childrens Medical Center Dallas, Dallas, Texas
Conditions: Tetrology of Fallot, Pulmonary Stenosis, Truncus Arteriosus, Transposition of Great Vessels, Pulmonary Atresia, Ross Procedure
Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation
Recruiting
Longitudinal studies show there is a steep increase in weight regain in the first 3-4 months after stopping GLP-1 receptor agonist medications (GLP-1s) and most patients regain most of their weight within a year. Insurers now question the utility of GLP-1s for weight loss as they are hesitant to cover these costs long-term (~$833 per person per month). Some patients would also prefer not to take these medications in perpetuity and are likely to struggle with lifelong adherence. These challenges... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Obesity
Doravirine Versus Integrase Inhibitors on Backbone of Emtricitabine and Tenofovir Alafenamide in HIV
Recruiting
This research application will explore the impact of the Non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine in the setting of established Nucleoside reverse transcriptase inhibitors (NRTIs) backbone [Tenofovir alafenamide (TAF) / Emtricitabine (FTC) as a possible therapeutic strategy to minimize the detrimental impact of ART-related toxicities on metabolism and instigators of atherosclerosis. Given the possible favorable role of NNRTI in pathogenesis of HIV-related dyslipidemia an... Read More
Gender:
Male
Ages:
Between 18 years and 70 years
Trial Updated:
03/07/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas +1 locations
Conditions: HIV I Infection, Cardiovascular Risk Factor, Lipid Metabolism Disorders
Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy
Recruiting
This is a Phase 1/2 Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration (AMD). This is a multicenter study, which will be conducted in two phases and will enroll up to a total of 63 subjects.
Gender:
All
Ages:
50 years and above
Trial Updated:
03/07/2024
Locations: A) Retina Foundation of the Southwest, Dallas, Texas
Conditions: Geographic Atrophy
PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial
Recruiting
This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 in adolescent patients 12 to 17 years of age with Hereditary Angioedema (HAE) type I or II.
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
03/06/2024
Locations: KalVista Investigative Site, Dallas, Texas
Conditions: Hereditary Angioedema
Pediatric Post-Approval Registry
Recruiting
This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe obstructive sleep apnea (OSA). Implanted subjects will be followed for 5 years post-implant.
Gender:
All
Ages:
Between 18 years and 21 years
Trial Updated:
03/06/2024
Locations: University of Texas Southwestern/Children's Hospital of Dallas, Dallas, Texas
Conditions: Obstructive Sleep Apnea
An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
Recruiting
This is an open-label, multicenter extension trial to evaluate the long-term safety of KVD900 in patients who are 12 years or older with HAE type I or II.
Gender:
All
Ages:
12 years and above
Trial Updated:
03/06/2024
Locations: KalVista Investigative Site, Dallas, Texas
Conditions: Hereditary Angioedema
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors
Recruiting
This is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor.
Gender:
All
Ages:
Between 6 months and 21 years
Trial Updated:
03/06/2024
Locations: University of Texas Southwestern Medical Center at Dallas, Dallas, Texas
Conditions: Medullary Thyroid Cancer, Infantile Myofibromatosis, Infantile Fibrosarcoma, Papillary Thyroid Cancer, Soft Tissue Sarcoma
Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2
Recruiting
This study is an open-label, international, multi-center, Phase 1 study in adult patients with solid tumors likely to express CLDN18.2.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Pancreas Neoplasm, Stomach Neoplasm, Gastrointestinal Neoplasms, Digestive System Neoplasm, Neoplasms by Site, Neoplasms
Episealer® Knee System IDE Clinical Study
Recruiting
The study is a randomized, prospective, multicenter, controlled clinical trial of the Episealer Knee System. The Episealer Knee System is intended for subjects with up to two focal femoral knee chondral or osteochondral lesion that is causing pain and/or disability and requires surgical treatment.
Gender:
All
Ages:
Between 30 years and 70 years
Trial Updated:
03/05/2024
Locations: North Texas Medical Research Institute, Dallas, Texas
Conditions: Degenerative Lesion of Articular Cartilage of Knee