There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Real-time Intraoperative Breast Cancer Visualization for Margin Assessment
NCT02807597
Recruiting
The investigators' preclinical data have demonstrated the feasibility of fluorescence-guided tumor resection by Cancer Vision Goggles (CVG) with LS301 in animal models. In this study, the investigators will conduct intraoperative imaging procedures that have minimal interference with ongoing surgery. The underlying hypothesis is that the accurate detection of all cancer cells highlighted by LS301 during surgery will reduce the number of breast cancer patients with margin positivity to less than... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Breast Cancer, Cancer of the Breast
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Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer
NCT05021237
Recruiting
To improve overall survival in patients with metastatic cervical cancer by loco-regional therapy with personalized ultra-fractionated radiation
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Adenosquamous Carcinoma of Cervix, Cervical Cancer, Metastasis, Stage IV Cervical Cancer FIGO 2018
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Project: Every Child for Younger Patients With Cancer
NCT02402244
Recruiting
This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.
Gender:
All
Ages:
25 years and below
Trial Updated:
02/27/2024
Locations: Medical City Dallas Hospital, Dallas, Texas +1 locations
Conditions: Central Nervous System Neoplasm, Childhood Immature Teratoma, Childhood Langerhans Cell Histiocytosis, Childhood Mature Teratoma, Congenital Mesoblastic Nephroma, Lymphoproliferative Disorder, Myeloproliferative Neoplasm, Stromal Neoplasm, Carcinoma In Situ, Malignant Solid Neoplasm, Desmoid Fibromatosis, Ganglioneuroma, Melanocytic Neoplasm, Neuroendocrine Neoplasm
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Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
NCT05145816
Recruiting
This study evaluates the safety, tolerability, recommended phase II (RP2) dose, and efficacy of Belantamab mafodotin for participants with Relapsed Refractory AL Amyloidosis (RRAL.)
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: AL Amyloidosis, Amyloidosis
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Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
NCT06284213
Recruiting
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID) is an NIH-funded consortium dedicated to finding biomarkers involved in age-related thinking and memory problems. Alzheimer's disease and other dementias leave signatures on brain scans or in the blood called biomarkers. The MarkVCID study will measure a panel of candidate biomarkers in 1800 participants and watch them closely to see what they tell us about changes in brain function and risk of memory loss. Ag... Read More
Gender:
All
Ages:
Between 60 years and 90 years
Trial Updated:
02/27/2024
Locations: University of Texas Southwestern, Dallas, Texas
Conditions: Cognitive Impairment, Dementia
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Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury
NCT04242602
Recruiting
Various methods have been studied to evaluate autoregulation. However, there is currently no universally accepted technique to assess integrity of the cerebral autoregulation neurovascular system. In the last decade, significant progress has been achieved in developing methods to assess cerebral autoregulation by quantifying cross-correlation between spontaneous oscillations in CBF or oxygenation and similar oscillations in arterial blood pressure. In this study the investigators will analyze t... Read More
Gender:
All
Ages:
Between 28 days and 18 years
Trial Updated:
02/27/2024
Locations: Children's Medical Center, Dallas, Texas
Conditions: Traumatic Brain Injury, Brain Injuries, Brain Injury, Vascular
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Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
NCT03391778
Recruiting
This trial will evaluate long term safety of participants who have received GlaxoSmithKline (GSK) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.
Gender:
All
Ages:
All
Trial Updated:
02/26/2024
Locations: GSK Investigational Site, Dallas, Texas
Conditions: Neoplasms
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Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
NCT05657301
Recruiting
VAN-2201 is Phase I clinical trial to assess the safety and tolerability of KH631 in subjects with neovascular AMD. KH631 is gene therapy designed to deliver a protein which targets and blocks VEGF via an adeno-associated viral vector. The standard of care for patients with neovascular AMD are anti-VEGF treaments, which have demonstrated improvement in vision and reduction in fluid. A one time placement of a product which inhibits VEGF has the potential to reduce the patient burden of regular in... Read More
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
02/23/2024
Locations: Kanghong Investigative Site, Dallas, Texas
Conditions: Age-Related Macular Degeneration
Register for Updates
SG2501 Safety Study in Subjects With Relapsed or Refractory Hematological Malignancies and Lymphoma.
NCT05293912
Recruiting
This is a phase Ia/Ib, first-in-Human, open-Label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of SG2501 in subjects with relapsed or refractory hematological malignancies and lymphoma.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Texas Oncology / Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Conditions: Hematological Malignancy, Lymphoma
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Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors
NCT05945823
Recruiting
This is a nonrandomized, uncontrolled, open-label, multicenter Phase 2 study to evaluate the efficacy, safety, and tolerability of futibatinib in combination with PD-1 antibody-based SoC therapy in adult patients with solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Dallas VA Medical Center, Dallas, Texas
Conditions: Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer, Esophageal Adenocarcinoma, Esophageal Squamous Cell Cancer, Siewert Type 1 GEJ Cancer, Pancreatic Cancer
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A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus
NCT06013995
Recruiting
The purpose of this study is to evaluate safety, drug levels and drug effects on cells and organs of the body, after receiving multiple increasing doses of BMS-986326 via intravenous (IV) infusion or subcutaneous (SC) injection, in participants with different forms of lupus.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/22/2024
Locations: Metroplex Clinical Research Center, Dallas, Texas
Conditions: Lupus
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Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression
NCT04002063
Recruiting
Depression is a common psychological disorder seen in 18.5% of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans. Improving the rate of depression recovery and remission is vital to enhance OEF/OIF/OND Veteran's ability to improve work and home adjustment and overall quality of life. OEF/OIF/OND Veterans have reported many barriers to following through with Cognitive therapy skills practice assignments, a key component of CBT therapy, the lead... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
02/22/2024
Locations: VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas
Conditions: Depression
Register for Updates