There are currently 1572 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures
Recruiting
Primary objective: To evaluate the safety and tolerability of cenobamate in pediatric subjects 2-17 years of age with partial-onset (focal) seizures
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
01/30/2024
Locations: Scottish Rite for Children, Dallas, Texas
Conditions: Partial Epilepsy
Behavioral and Neural Correlates of Post-Stroke Fatigue
Recruiting
The goal of this phase I/II clinical trial is to determine the behavioral and neural effects of 5-daily transcranial direct current stimulation on post-stroke fatigue. The three aims are: Aim 1: Investigate the behavioral effect of 5 daily sessions of anodal tDCS over the ipsilesional M1 on PSF. Aim 2: Investigate the neurophysiological effect of 5 daily sessions of anodal tDCS over the ipsilesional M1. Aim 3: Determine the relationship between changes in M1 excitability, brain connectivity a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Texas Woman's University, Dallas, Texas
Conditions: Stroke, Fatigue
A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
Recruiting
The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult and adolescent participants with severe sickle cell disease (SCD).
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
01/30/2024
Locations: Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Conditions: Sickle Cell Disease, Hemoglobinopathies
Exposure Therapy Consortium (ETC) for Anxiety Sensitivity
Recruiting
The current study seeks to test differences between a single-session large-group format of standard exposure, enhanced exposure, and a control condition in treating anxiety sensitivity. It is hypothesized that 1) participants assigned to either exposure condition will evidence greater reductions in anxiety sensitivity from pre-treatment to posttreatment relative to those in the control condition; 2) participants assigned to the enhanced exposure condition will evidence greater reductions in anxi... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
01/30/2024
Locations: Southern Methodist University, Dallas, Texas
Conditions: Elevated Anxiety Sensitivity
A Randomized Multicenter Study for Isolated Skin Vasculitis
Recruiting
Multi-center sequential multiple assignment randomized trial comparing the effectiveness of three different standard of care treatment options for patients with isolated skin vasculitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Primary Cutaneous Vasculitis, Cutaneous Polyarteritis Nodosa, IgA Vasculitis, Henoch-Schönlein Purpura
Get With the Guidelines Atrial Fibrillation Registry
Recruiting
Get With The Guidelines-Atrial Fibrillation is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients. At the same time, it offers a means of monitoring the quality of AFib care in U.S. hospitals and building a database for continued research and further quality improvement.
Gender:
All
Ages:
Between 18 years and 125 years
Trial Updated:
01/29/2024
Locations: Kelly Burlison, Dallas, Texas
Conditions: Atrial Fibrillation, Atrial Flutter
CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC
Recruiting
The objective of this study is to assess safety and efficacy of CAB-AXL-ADC in NSCLC
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Non-Small-Cell Lung Cancer
CAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)
Recruiting
The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumors
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Non Small Cell Lung Cancer, Triple Negative Breast Cancer, Melanoma, Head and Neck Cancer
Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies
Recruiting
This is a Phase 1, open-label, first-in-human study of CTX-471 administered as a monotherapy or in combination with pembrolizumab in patients with metastatic or locally advanced malignancies that have progressed while receiving an approved PD-1 or PD-L1 inhibitor. The study will be conducted in 2 treatment arms (Monotherapy Arm 1 and Combination Arm 2). Each arm will have two parts: Part 1 Dose Escalation and Part 2 Dose Expansion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Locally Advanced Solid Tumor, Metastatic Cancer, Non-small Cell Lung Cancer, Small Cell Lung Cancer, Mesothelioma, Melanoma, Head and Neck Cancer
Dose Escalation and Expansion Study of BH3120 in Advanced or Metastatic Solid Tumors
Recruiting
This is a First-in-Human, Phase 1, Dose-Escalation and Dose-Expansion study of BH3120 to assess safety, tolerability, MTD, RP2D, PK, and efficacy in patients with advanced or metastatic solid tumors. Dose-Escalation part is planned to establish the MTD or RD for Dose-Expansion part, while Dose-Expansion part is designed to assess potential efficacy of BH3120 when administered at the RD to subjects in indication-specific expansion cohorts.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Mary Crowley Cancer Research, Dallas, Texas
Conditions: Advanced or Metastatic Solid Tumors
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
All
Ages:
Between 120 days and 21 years
Trial Updated:
01/29/2024
Locations: University of Texas Southwest Medical Center (UTSW), Dallas, Texas
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
Impella Real-World Surveillance of Patients Using Sodium Bicarbonate
Recruiting
The population enrolled in this study are all subjects who received an Impella in which a bicarbonate-based purge solution was used.
Gender:
All
Ages:
All
Trial Updated:
01/29/2024
Locations: Baylor Scott and White (Baylor Heart and Vascular), Dallas, Texas
Conditions: Cardiogenic Shock, High Risk PCI