There are currently 164 clinical trials in Plano, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including The Heart Hospital Baylor Plano, Texas Oncology - Plano East, GSK Investigational Site and Texas Back Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)
NCT05383209
Recruiting
A prospective, randomized, double-masked study evaluating the ocular efficacy and safety of two doses of the EYP-1901 intravitreal insert compared to sham
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: EyePoint Investigative Site, Plano, Texas
Conditions: Nonproliferative Diabetic Retinopathy
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EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial)
NCT05151172
Recruiting
Stroke occurs when a blood clot causes a blockage in a blood vessel (artery) within the brain. This type of stroke is called an ischemic stroke and carries a high risk of disability or death. Stroke must be treated very fast. Any delay of even 10 minutes can result in the difference between an independent and a disabled outcome, and in some cases between life and death. Endovascular therapy (EVT) or Thrombectomy is a procedure to remove the blood clot (thrombus) from a blood vessel to reopen it... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/07/2024
Locations: Texas stroke Institute, Plano, Texas
Conditions: Acute Ischemic Stroke
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Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.
NCT05690204
Recruiting
The aim of this study is to confirm the safety and pharmacological characteristics of SAP-001, evaluate its efficacy in lowering sUA and tophus burden, and identify the appropriate dose regimen for future studies in adult subjects with gout, with or without tophi, and hyperuricemia refractory to SoC XOI therapy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2024
Locations: Texas Site, Plano, Texas
Conditions: Gout
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Impella Real-World Surveillance of Patients Using Sodium Bicarbonate
NCT05820451
Recruiting
The population enrolled in this study are all subjects who received an Impella in which a bicarbonate-based purge solution was used.
Gender:
All
Ages:
All
Trial Updated:
01/29/2024
Locations: The Heart Hospital Baylor Plano, Plano, Texas
Conditions: Cardiogenic Shock, High Risk PCI
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The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment of IVH
NCT05113381
Recruiting
The primary goal of this study is to assess the occurrence of flushing interventions to address occlusions during the treatment of interventricular hemorrhage (spontaneous primary IVH or secondary IVH due to ruptured aneurysm).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Medical City Plano, Plano, Texas
Conditions: Intraventricular Hemorrhage, Subarachnoid Hemorrhage
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Pelvic Fixation and Fusion During Multilevel Spinal Surgery
NCT05640908
Recruiting
PAULA aims to collect data on the safety, performance, and effectiveness of iFuse Bedrock Granite (GRANITE) in patients who have spinal fusion surgery with pelvic fixation/ fusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Texas Back Institute, Plano, Texas
Conditions: Spinal Fusion, Deformity of Spine
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Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
NCT06212518
Recruiting
The primary objective of this study is to analyze smart phone-based Transdermal Optical Imaging (TOI) features to develop a model that can discern hydration status, including: 1) at various timepoints throughout a 24-hour period in healthy adults from the general population (GENPOP), and 2) before and after a team coach-led training session in athletes competing in a sport (ATHLETE). TOI data will be collected alongside standard reference measures of hydration status. In this study each subject... Read More
Gender:
All
Ages:
Between 14 years and 65 years
Trial Updated:
01/13/2024
Locations: PepsiCo R&D, Gatorade Sports Science Institute, Plano, Texas
Conditions: Dehydration
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TRISCEND II Pivotal Trial
NCT04482062
Recruiting
Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: Baylor Heart Hopsital Plano, Plano, Texas
Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
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Advancing Cath Lab Results With FFRangio Coronary Physiology Assessment
NCT05893498
Recruiting
To test whether FFRangio-guided treatment is non-inferior to conventional pressure wire-guided treatment in patients with coronary artery disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: Baylor Scott & White The Heart Hospital - Plano, Plano, Texas
Conditions: Percutaneous Coronary Intervention
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PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection
NCT05174767
Recruiting
Prospective, non-randomized, multicenter clinical investigation to assess the safety and effectiveness of AMDS in the treatment of patients with acute DeBakey type I dissection, with evidence of malperfusion, through open surgical repair.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/11/2024
Locations: Baylor Scott & White The Heart Hospital Plano, Plano, Texas
Conditions: Acute Aortic Dissection
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A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD
NCT05721235
Recruiting
The is a multicenter, dose-optimized, open-label, safety/ tolerability and pharmacokinetic (PK) study with Azstarys® in children 4 and 5 years of age with attention-deficit/hyperactivity disorder (ADHD). The primary objective is to determine the safety and tolerability of treating children 4 and 5 years-of-age with ADHD with Azstarys® for up 12 months. Approximately 100 subjects will be enrolled. Approximately 20 sites will participate.
Gender:
All
Ages:
Between 4 years and 5 years
Trial Updated:
01/04/2024
Locations: AIM Trials, Plano, Texas
Conditions: Attention Deficit/Hyperactivity Disorder
Register for Updates
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Texas Oncology - Plano East, Plano, Texas +1 locations
Conditions: Breast Cancer
Register for Updates