There are currently 156 clinical trials in Plano, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including The Heart Hospital Baylor Plano, Texas Oncology - Plano East, GSK Investigational Site and Texas Back Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2023
Locations: Baylor Research Institute, Plano, Texas
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Misago® RX Self-expanding Peripheral Stent for Common and/or External Iliac Artery
NCT02793492
Recruiting
This is a multi-center, single arm, non-randomized, prospective clinical study using the Misago® RX Self-expanding Peripheral Stent for treatment of de novo, restenotic, and/or occlusive lesion(s) of the common and/or external iliac artery.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2023
Locations: The Heart Hospital Baylor Plano, Plano, Texas
Conditions: Iliac Artery Stenosis
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Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial
NCT02000115
Recruiting
The objective of the PORTICO pivotal IDE trial is to evaluate the safety and effectiveness of the St Jude Medical (SJM) Portico Transcatheter Heart Valve and Delivery Systems (Portico) in the treatment of severe symptomatic aortic stenosis via transfemoral and alternative delivery methods in high risk and extreme risk patients.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/24/2023
Locations: The Heart Hospital Baylor Plano, Plano, Texas
Conditions: Aortic Valve Stenosis
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Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: AIM Trials, LLC, Plano, Texas
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
NCT06041269
Recruiting
RENOIR Study: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe Rheumatoid Arthritis (RA)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2023
Locations: Anaptys Bio Investigative Site 10-110, Plano, Texas
Conditions: Rheumatoid Arthritis
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A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)
NCT04636801
Recruiting
The purpose of the study is to evaluate the efficacy and safety of two doses of CHF6001 (Tanimilast), as add-on to maintenance triple therapy in the target patient population.
Gender:
All
Ages:
40 years and above
Trial Updated:
10/02/2023
Locations: Chiesi Clinical Trial - Site 840409, Plano, Texas
Conditions: Chronic Obstructive Pulmonary Disease
Register for Updates
Abt, Concussion Screen Use Recovery Time
NCT05373992
Recruiting
A two-year parallel randomized clinical trial study to examine the effect of screen time (ST) restriction, exercise alone, and combined ST-restricted-exercise when compared to stretching only (control group) on sports related concussion recovery time among adolescents aged 12 to 17 years. Study hypothesis 1 - There will be significant differences between the treatment and the control arms' mean recovery time (days). Study hypothesis 2 - The ST-restricted & exercise treatment arm will have a sign... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
09/25/2023
Locations: Children's Health - Andrews Institute, Plano, Texas
Conditions: Sport-related Concussion
Register for Updates
AltaValve Early Feasibility Study Protocol
NCT03997305
Recruiting
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: Baylor Scott & White, Plano, Texas
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
Register for Updates
A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control
NCT05705440
Recruiting
The purpose of this follow-up study is to describe the safety in subsequent pregnancies in participants who were previously administered the RSVPreF3 maternal vaccine or control during any prior RSV MAT study. The study participants enrolled in this follow-up study received RSVPreF3 maternal vaccination (any dose) or controls during the following prior RSV MAT studies: RSV MAT-001 (NCT03674177), RSV MAT-004 (NCT04126213), RSV MAT-010 (NCT05045144), RSV MAT-011 (NCT04138056), RSV MAT-009 (NCT046... Read More
Gender:
Female
Ages:
Between 9 years and 49 years
Trial Updated:
08/30/2023
Locations: GSK Investigational Site, Plano, Texas
Conditions: Respiratory Syncytial Virus Infections
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A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab
NCT05388474
Recruiting
The virological efficacy of ibalizumab has been clearly demonstrated in multiple clinical trials. This study will expand ibalizumab's clinical data set and allow a better understanding of the virologic response durability on ARV regimens with or without ibalizumab in a heterogeneous real-world patient population. Additional data on the efficacy and safety of ibalizumab and its impact on patient reported outcomes will be captured until study end. Primary Objective: To evaluate the long-term eff... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: North Texas Infectious Diseases Consultants, P.A., Plano, Texas
Conditions: HIV Infections, Multi-Antiviral Resistance
Register for Updates
Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR
NCT05862558
Recruiting
To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-carotid)
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/08/2023
Locations: Baylor Scott and White Heart Hospital, Plano, Texas
Conditions: Iliac Disease, Aortic Valve Stenosis
Register for Updates
Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites
NCT04288921
Recruiting
A Multicenter Study Conducted to Evaluate the Performance of the LumiraDx Influenza A/B + RSV Test at Point of Care Testing Sites
Gender:
All
Ages:
All
Trial Updated:
03/10/2023
Locations: North Texas Family Practice, Plano, Texas
Conditions: Influenza, Human, Respiratory Syncytial Virus Infections
Register for Updates