Pain Study to See if Ultram ER Will Provide Relief to Subjects Whose Pain is Not Well Controlled by Narcotics
NCT00505531
Terminated
The Massachusetts General Hospital Center for Translational Pain Research is conducting a research study to see if Ultram ER, an FDA-approved pain medication, would be helpful in providing pain relief in subjects whose chronic pain is not well controlled on narcotic pain medicine.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/21/2020
Locations: MGH Center for Translational Pain Research, Boston, Massachusetts
Conditions: Chronic Pain
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Music Utilization in Sedation and Induction in Colonoscopy
NCT04468048
Withdrawn
Conscious sedation (CS) if often used in the field of gastroenterology to alleviate pain and discomfort with interventional procedures. Although CS is relatively safe, there is concern for the development of cardiopulmonary complications. Music has been shown in multiple studies to decrease anxiety and improve patient satisfaction following cardiac, pulmonary, and surgical procedures. This is a prospective single-blinded randomized control trial that will examine the effects of active music part... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/07/2020
Locations: The Brooklyn Hospital Center, Brooklyn, New York
Conditions: Colonoscopy
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ITT-5 Mechanisms of Spermatogenesis in Man
NCT02147964
Withdrawn
The purpose of this investigational drug study is to determine how much male hormone, testosterone, is needed to maintain sperm production in the testis.
Gender:
MALE
Ages:
Between 18 years and 55 years
Trial Updated:
12/16/2019
Locations: University of Washington Medical Center (Health Sciences), Seattle, Washington
Conditions: Gonadotropin Deficiency
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Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults
NCT02911753
Completed
This study aims to 1) assess the feasibility and acceptability of a prescribed beverage intervention in 50 obese Hispanic adults ages 18-64 years over 6 weeks; and 2) assess preliminary effects of the beverage intervention on cholesterol and triglyceride levels as well as other markers of health such as blood pressure, glucose and markers of inflammation. This project, if successful, will provide early evidence that targeting dietary behavior around beverage intake could be a novel and easily ad... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
10/22/2019
Locations: University of Arizona Collaboratory for Metabolic Disease Prevention and Treatment, Tucson, Arizona
Conditions: Obesity, Hypercholesterolemia, Hyperglycemia, Hypertriglyceridemia
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Neural Correlates of Working Memory Training for HIV Patients
NCT02602418
Unknown
Despite potent combination antiretroviral therapy, cognitive (memory and concentration) problems continue to occur in up to 50% of HIV-infected individuals, especially in older infected individuals, and those who abuse alcohol, marijuana or psychostimulants. Since no effective treatments are available to these individuals with cognitive problems, conservative estimates indicate that the cost of care for these patients could double in the next two decades. To address this urgent problem, this stu... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/01/2019
Locations: University of Maryland School of Medicine, Baltimore, Maryland
Conditions: HIV Infection
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Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
NCT02145247
Completed
Women with PCOS suffer from excess male hormone (androgen) production by the ovary. Androgen is made by cells that surround follicles that contain eggs. As the follicles (and eggs) grow and mature, there are more androgen producing cells. Women with PCOS have more follicles than normal women and therefore more androgen producing cells. While androgen production has been associated with the number of follicles, the relationship to the individual size of follicles in PCOS or normal women. This stu... Read More
Gender:
FEMALE
Ages:
Between 18 years and 37 years
Trial Updated:
08/08/2019
Locations: University of California, San Diego, La Jolla, California
Conditions: Polycystic Ovary Syndrome
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Prospective Study on the Treatment of Unsuspected Pulmonary Embolism in Cancer Patients
NCT01727427
Completed
The same initial and long-term anticoagulation is suggested for unsuspected pulmonary embolism as for patients with symptomatic embolism. Based on these indications, cancer patients with unsuspected pulmonary embolism would be anticoagulated for at least 6 months or until the disease is active, which in most cases would mean indefinite treatment. In fact, dedicated studies on the treatment of unsuspected pulmonary embolism are missing, leaving doubts over the need for (indefinite) anticoagulatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2019
Locations: D.C. Veterans Affairs Medical Center, Washington, District of Columbia +45 locations
Conditions: Unsuspected Pulmonary Embolism
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Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
NCT01154192
Completed
In women with polycystic ovary syndrome (PCOS), the cardinal physiological abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels. Studies to determine the alteration in ovarian steroidogenesis that lead to abnormal production of ovarian androgens have revealed increased CYP17 gene expression with accentuated 17-hydroxylase activity leading to exaggerated 17-hydroxyprogesterone (17P) responses to luteinizing hormone (LH) sti... Read More
Gender:
FEMALE
Ages:
Between 12 years and 18 years
Trial Updated:
04/22/2019
Locations: UCSD School of Medicine, La Jolla, California
Conditions: PCOS
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Auricular Acupuncture to Facilitate Outpatient Opioid Weaning
NCT02882048
Terminated
This study is to compare two groups undergoing opioid weaning as ordered by their referring physicians. One group will undergo the standard opioid weaning process and the other group will have the addition of the NADA Protocol to the weaning process.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/28/2019
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Narcotic Addiction
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Alternative Sedation During Bronchoscopy
NCT01158820
Completed
This protocol hopes to determine whether the use of dexmedetomidine-ketamine can reduce the use of standard of care fentanyl-midazolam sedation during bronchoscopy. This may result in less respiratory depression while providing better compliance with the procedure.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
02/05/2019
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Sedation
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Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
NCT00747617
Completed
The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH) secretion in this disorder. The investigators hypothesize that in PCOS women ovarian theca cells, which are responsible for androgen synthesis, are more sensitive to LH stimulation compared to that of theca cells from normal women. To test this hypothesis, the investigators prop... Read More
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
10/25/2018
Locations: University of California, San Diego, School of Medicine, La Jolla, California
Conditions: Polycystic Ovary Syndrome
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Prevalence of Secondary Hypogonadism in Male Patients on Chronic Opioid Therapy for Cancer-Related Pain Syndromes
NCT00529230
Terminated
Primary Objective: 1. To determine the prevalence of secondary hypogonadism in male patients on chronic opioid therapy for cancer-related pain syndromes. Secondary Objective: 1. To determine the degree of sexual dysfunction, fatigue, and depression prevalent in male patients on chronic opioid therapy for cancer-related pain syndromes.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/24/2018
Locations: U.T.M.D. Anderson Cancer Center, Houston, Texas
Conditions: Advanced Cancer, Hypogonadism, Pain
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