Co-administration of Low Dose hCG at the Time of GnRH Agonist Trigger or 35 Hours Later for the Prevention of OHSS
NCT01815138
Completed
This a prospective randomized double blind study involving patients at high risk of OHSS development with peak serum E2 levels \< 4,000 pg/ml comparing the ongoing pregnancy rates in patients who receive adjuvant hCG 1,000 IU at the time of GnRH agonist trigger or adjuvant hCG 1,500 IU 35 hours after GnRH agonist trigger.
Gender:
FEMALE
Ages:
Between 18 years and 39 years
Trial Updated:
09/25/2018
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Ovarian Hyperstimulation Syndrome
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TPI 287 in Breast Cancer Metastatic to the Brain
NCT01332630
Completed
The goal of the first part of this clinical research study is to find the highest tolerable dose of TPI-287 in patients with breast cancer that has spread to the brain. The goal of the second part of this study is to learn if TPI-287 can control breast cancer that has spread to the brain. The safety of this drug will also be studied.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/18/2018
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Breast Cancer
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Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
NCT01229449
Completed
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/14/2018
Locations: Premier Research, Austin, Texas
Conditions: Post-operative Pain
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Orphenadrine and Methocarbamol for LBP
NCT02665286
Completed
Low back pain is a common cause of visit to emergency department. It is not clear if skeletal muscle relaxants are of benefit for patients with acute low back pain. This is a randomized study to determine if skeletal muscle relaxants, when combined with naproxen, improve outcomes more than naproxen alone
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
05/29/2018
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Low Back Pain
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Study of the Safety and Immune Response of a Meningococcal Conjugate Vaccine Administered to Healthy Adolescents
NCT00262041
Completed
The purpose of this study is to evaluate the safety and immunogenicity of Novartis Meningococcal ACWY Conjugate Vaccine in comparison to licensed meningococcal polysaccharide vaccine administered to healthy adolescents ages 11 to 17 years.
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
05/17/2018
Locations: Not set, Rochester, Minnesota +2 locations
Conditions: Prevention of Meningococcal Disease
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Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
NCT00989781
Completed
Jeffrey Chang MD is conducting a research study to learn more about the increased male hormone levels, otherwise known as androgens, seen in women with polycystic ovary syndrome (PCOS). Women with PCOS have ovaries that are comprised of many cysts, or follicles. They also have irregular or absent menstrual periods and symptoms of increased male hormones, such as facial hair or acne. In each part of the study (except part 4 which is for PCOS women only) we will be comparing responses of PCOS wome... Read More
Gender:
FEMALE
Ages:
Between 18 years and 37 years
Trial Updated:
05/01/2018
Locations: UCSD Medical Center, San Diego, California
Conditions: Polycystic Ovary Syndrome
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Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine
NCT00435461
Completed
The primary objective of this study is to compare the nighttime symptom relief of fluticasone furoate nasal spray and oral fexofenadine
Gender:
ALL
Ages:
12 years and above
Trial Updated:
02/06/2018
Locations: GSK Investigational Site, Austin, Texas +5 locations
Conditions: Rhinitis, Allergic, Seasonal
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"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
NCT03081416
Completed
This is a randomized, single-blind, placebo controlled trial to evaluate the efficacy of sub-dissociative dose ketamine versus standard care therapy for acute headache management of in patients presenting to the emergency department with headache as the chief compliant.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/16/2018
Locations: Brooke Army Medical Center, San Antonio, Texas
Conditions: Headache, Intranasal Ketamine
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Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee
NCT02449369
Completed
This is a prospective, three-arm, randomized, open-label trial to determine if a new pain control protocol which includes regular dosing of intravenous acetaminophen and orphenadrine for 48 hours after total knee surgery reduces the need for opioid pain medication and reduces average pain scores.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/29/2017
Locations: Florida Hospital Winter Park, Winter Park, Florida
Conditions: Unilateral Knee Arthroplasty
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Observational Study of Kibow Biotics in Chronic Kidney Failure Patients
NCT01450657
Completed
A specifically formulated probiotic product comprised of defined and tested microbial strains may afford renoprotection in what has been generally called "Enteric DialysisTM". However, it is also referred to as enteric toxin reduction technology. Our hypothesis is to assess the potential benefits in devising a bowel-based probiotic formulation (Kibow® Biotics/RenadylTM) as a dietary supplement product for patients undergoing standardized care of treatment for their CKD stage 3 and stage 4 condit... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/15/2017
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Chronic Kidney Failure
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Follicle Stimulating Hormone (FSH) to Improve Testicular Development in Men With Hypogonadism
NCT00064987
Terminated
Men with idiopathic hypogonadotropic hypogonadism (IHH, Kallmann Syndrome) may have small testicular size, low testosterone levels, no history of puberty, and infertility. These men lack a hormone called gonadotropin releasing hormone (GnRH) that stimulates the development and maturation of the testes. This study will investigate the impact of hormonal treatments on men with IHH. The goal of hormonal therapy is to maximize the potential fertility in these individuals.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/05/2017
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hypogonadism, Kallmann Syndrome
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Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects With Moderate to Severe Plaque Psoriasis
NCT03058744
Completed
Suppression Potential of Topically Applied IDP-118 Lotion and HP Monad Lotion in Subjects with Moderate to Severe Plaque Psoriasis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/08/2017
Locations: Valeant Site 12, Anaheim, California +11 locations
Conditions: Psoriasis
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