Combination Chemotherapy With or Without Epirubicin in Treating Women With Stage I or Stage II Breast Cancer
NCT00003577
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether combination chemotherapy plus epirubicin is more effective than combination chemotherapy alone for stage I or stage II breast cancer. PURPOSE: This randomized phase III trial is studying combination chemotherapy alone to see how well it works compared to combination chemotherapy and epirubicin... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
12/18/2013
Locations: University of Cambridge, Cambridge, England
Conditions: Breast Cancer
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Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer
NCT00003893
Completed
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumors cells. Combining chemotherapy with radiation therapy may kill more tumor cells. It is not yet known which regimen of chemotherapy plus radiation therapy is more effective for early-stage breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two different regimens of adjuvant chemotherap... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
12/18/2013
Locations: Queen Elizabeth Hospital at University of Birmingham, Birmingham, England
Conditions: Breast Cancer
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Combination Chemotherapy in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
NCT00040690
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients who have Burkitt's lymphoma or Burkitt's leukemia.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
12/18/2013
Locations: Medical Research Council Clinical Trials Unit, London, England
Conditions: Leukemia, Lymphoma
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Adjuvant Chemotherapy Compared With Observation in Treating Patients With Resected Early Stage Ovarian Epithelial Cancer
NCT00002477
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of adjuvant therapy using platinum-based chemotherapy drugs with no adjuvant therapy in treating patients with early stage invasive ovarian epithelial cancer.
Gender:
FEMALE
Ages:
All
Trial Updated:
12/17/2013
Locations: Cochrane Cancer Network, Oxford, England
Conditions: Ovarian Cancer
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Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
NCT00004218
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for chronic lymphocytic leukemia. PURPOSE: This randomized phase III trial is studying chlorambucil to see how well it works compared to fludarabine and cyclophosphamide or fludarabine alone in treating patients with newly diagnosed chronic lymphocytic leukemia.
Gender:
ALL
Ages:
All
Trial Updated:
12/17/2013
Locations: Hospital Italiano de Buenos Aires, Buenos Aires, Not set +85 locations
Conditions: Leukemia
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Combination Chemotherapy With or Without Rituximab in Treating Patients With Mantle Cell Lymphoma
NCT00053092
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. It is not yet known if combination chemotherapy is more effective with or without rituximab in treating mantle cell lymphoma. PURPOSE: Randomized phase II trial to compare the effectiveness of fludarabine and cyclophos... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/17/2013
Locations: Peter MacCallum Cancer Centre, East Melbourne, Victoria +1 locations
Conditions: Lymphoma
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Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis
NCT00414128
Completed
The purpose of this study is to investigate whether mycophenolate mofetil is effective as treatment for new cases of ANCA associated vasculitis.
Gender:
ALL
Ages:
All
Trial Updated:
12/05/2013
Locations: Addenbrookes Hospital, Cambridge, Cambridgeshire
Conditions: Vasculitis
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Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma
NCT00002898
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug with surgery and/or radiation therapy may kill more tumor cells. PURPOSE: This randomized phase III trial is studying surgery followed by different regimens of combination chemotherapy given together with radiation therapy and/or additional surgery to compare how well they work in treating patients with soft tissue sarcoma.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
12/03/2013
Locations: Institute of Child Health, Bristol, England
Conditions: Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma
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Epirubicin and Cyclophosphamide Compared With Epirubicin and Paclitaxel in Treating Women With Metastatic Breast Cancer
NCT00002953
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of epirubicin and cyclophosphamide with epirubicin and paclitaxel in treating women with metastatic breast cancer.
Gender:
FEMALE
Ages:
All
Trial Updated:
12/03/2013
Locations: Groote Schuur Hospital, Cape Town, Cape Town, Not set +18 locations
Conditions: Breast Cancer
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Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease
NCT00002987
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy plus radiation therapy with radiation therapy alone in treating patients with early-stage Hodgkin's disease.
Gender:
ALL
Ages:
Between 16 years and 75 years
Trial Updated:
12/03/2013
Locations: Groote Schuur Hospital, Cape Town, Cape Town, Not set +17 locations
Conditions: Lymphoma
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Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
NCT00003437
Unknown
RATIONALE: Hormone therapy may stop the growth of cancer cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more cancer cells. It is not yet known which hormone therapy and chemotherapy regimen is most effective for acute lymphoblastic leukemia. PURPOSE: Randomized phase III trial to compare the effectiveness of different steroid therapy and chemotherapy regimens in treating ch... Read More
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
12/03/2013
Locations: Oxford Radcliffe Hospital, Oxford, England
Conditions: Leukemia
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Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS
NCT00003859
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether undergoing surgery plus radiation therapy is more effective with or without chemotherapy for primitive neuroectodermal tumors of the CNS. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery plus radiation therapy with or without chemotherapy in treating patients... Read More
Gender:
ALL
Ages:
Between 3 years and 16 years
Trial Updated:
12/03/2013
Locations: St. James's Hospital, Leeds, England
Conditions: Brain and Central Nervous System Tumors
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