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Cyclophosphamide Treatment Options in United Kingdom
A collection of 244 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the United Kingdom . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.
181 - 192 of 244
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Clinical Trial Phase
Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery.
PURPOSE: Phase III trial to determine the effectiveness of combination chemotherapy given before surgery in treating children who have localized neuroblastoma.
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
12/03/2013
Locations: St. Anna Children's Hospital, Vienna, Not set +11 locations
Conditions: Neuroblastoma
Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating children with metastatic rhabdomyosarcoma or other malignant mesenchymal tumors.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
12/03/2013
Locations: Centre Leon Berard, Lyon, Not set +21 locations
Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer
Completed
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen. Combining combination chemotherapy with hormone therapy may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy with or without tamoxifen in treating women with stage I or stage II breast cancer that can be surgically removed.
Gender:
FEMALE
Ages:
All
Trial Updated:
11/05/2013
Locations: Leicester Royal Infirmary NHS Trust, Leicester, England +9 locations
Conditions: Breast Cancer
Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer
Completed
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen. Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with hormone therapy may kill more tumor cells. It is not yet known which treatment regimen is most effective for breast cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of tamoxifen with that of... Read More
Gender:
FEMALE
Ages:
70 years and below
Trial Updated:
11/05/2013
Locations: University Hospitals of Leicester, Leicester, England +9 locations
Conditions: Breast Cancer
Tamoxifen With or Without Combination Chemotherapy in Treating Postmenopausal Women With Operable Invasive Breast Cancer
Completed
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen. Combining combination chemotherapy with hormone therapy may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare the effectiveness of tamoxifen with or without combination chemotherapy in treating postmenopausal women with stage I or stage II breast cancer that can be surgically removed.
Gender:
FEMALE
Ages:
70 years and below
Trial Updated:
11/05/2013
Locations: Aberdeen Royal Infirmary, Aberdeen, Scotland +8 locations
Conditions: Breast Cancer
Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more tumor cells. It is not yet known which treatment regimen is more effective for breast cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of standard cyclophosphamide, methotrexate, and fluorouracil with that of high-dose combination chemotherapy... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/05/2013
Locations: St. Vincent's Hospital, Dublin, Not set +20 locations
Conditions: Breast Cancer
Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective following surgery for breast cancer.
PURPOSE: Randomized phase III trial to study the effectiveness of combination chemotherapy consisting of cyclophosphamide, methotrexate, and fluorouracil with or without epirubicin in treating women who have early stage breast cancer.
Gender:
FEMALE
Ages:
All
Trial Updated:
11/05/2013
Locations: University Hospitals of Leicester, Leicester, England +9 locations
Conditions: Breast Cancer
Combination Chemotherapy in Treating Women With Breast Cancer
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether doxorubicin plus docetaxel is more effective than doxorubicin plus cyclophosphamide for breast cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of doxorubicin in combination with either docetaxel or cyclophosphamide in treating women who have previously untreated, advanc... Read More
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
11/05/2013
Locations: C.R.C. Beatson Laboratories, Glasgow, Scotland
Conditions: Breast Cancer
Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. It is not yet known whether high-dose chemotherapy plus peripheral stem cell transplantation is more effective than standard chemotherapy for breast cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness o... Read More
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
11/05/2013
Locations: C.R.C. Beatson Laboratories, Glasgow, Scotland
Conditions: Breast Cancer
Comparison of Three Combination Chemotherapy Regimens in Treating Women With Stage I or Stage II Breast Cancer
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: This randomized phase II trial is studying three regimens of combination chemotherapy to compare how well they work in treating women with stage I or stage II breast cancer.
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
11/05/2013
Locations: Royal Marsden NHS Foundation Trust - Surrey, Sutton, England
Conditions: Breast Cancer
Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer
Completed
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Currently patients with breast cancer are treated with one of several very similar combinations of drugs. Analysis of biomarkers in tumor tissue may help doctors predict how well patients with breast cancer will respond to treatment and help doctors choose the best drug regimen to treat each patient.
PURPOSE: This randomized phase III trial is studying giving different reg... Read More
Gender:
FEMALE
Ages:
70 years and below
Trial Updated:
10/23/2013
Locations: Institut Jules Bordet, Brussels, Not set +38 locations
Conditions: Breast Cancer
High Dose Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Bone marrow transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells. It is not yet known whether high dose chemotherapy plus bone marrow transplantation is more effective than high dose chemotherapy alone for intermediate- or high-grade non-Hodgkin's lymphoma.
PURPOSE: Randomized phase III trial to compare the effectiveness of h... Read More
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
09/19/2013
Locations: Charles University Hospital, Prague (Praha), Not set +71 locations
Conditions: Lymphoma
181 - 192 of 244