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Cyclophosphamide Treatment Options in United Kingdom
A collection of 244 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the United Kingdom . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.
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Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
Recruiting
Follicular lymphoma (FL) is the second most common B-cell cancer and the most common type of cancer of lymphocytes. Unfortunately, this disease is incurable with conventional treatment and the disease recurs in almost all patients. This study will assess how safe and effective epcoritamab is in combination with lenalidomide and rituximab (R2) in treating adult participants with previously untreated FL. Adverse events and change in disease condition will be assessed.
Epcoritamab is an investigat... Read More
Follicular lymphoma (FL) is the second most common B-cell cancer and the most common type of cancer of lymphocytes. Unfortunately, this disease is incurable with conventional treatment and the disease recurs in almost all patients. This study will assess how safe and effective epcoritamab is in combination with lenalidomide and rituximab (R2) in treating adult participants with previously untreated FL. Adverse events and change in disease condition will be assessed.
Epcoritamab is an investigational drug being developed for the treatment of FL. Study doctors put the participants in 1 of 5 groups, called treatment arms. Each group receives a different treatment. Around 1095 adult participants with previously untreated FL will be enrolled in approximately 250 sites across the world.
Participants will receive R2 (intravenous \[IV\] infusion of rituximab (R) and oral capsules of lenalidomide) alone or in combination with subcutaneous injections of epcoritamab. Participants may also receive investigator's choice chemoimmunotherapy (CIT): IV infusion of obinutuzumab (G) and IV injections of cyclophosphamide, IV injections of doxorubicin, IV injections of vincristine, oral tablets of prednisone (CHOP) \[G-CHOP\]/ R-CHOP or G and IV infusion of bendamustine (Benda) \[G-Benda\]/R-Benda. The total treatment duration will be 120 weeks for all arms except A2, which is 24 weeks of treatment.
There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: Scripps Mercy Hospital /ID# 265393, San Diego, California +244 locations
Scripps Mercy Hospital /ID# 265393, San Diego, California
Sansum Clinic Research /ID# 261596, Santa Barbara, California
Rocky Mountain Cancer Centers - Boulder /ID# 261203, Boulder, Colorado
Christiana Care Health Service /ID# 261207, Newark, Delaware
Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 262445, Jacksonville, Florida
Advent Health /ID# 261578, Orlando, Florida
Orlando Health Cancer Institute /ID# 260983, Orlando, Florida
Beacon Cancer Care /ID# 260670, Coeur d'Alene, Idaho
Northwestern University- Robert H. Lurie Comprehensive Cancer Center /ID# 259814, Chicago, Illinois
Cancer Care Specialists Of Central Illinois /ID# 272464, Decatur, Illinois
Illinois Cancer Care, PC /ID# 261526, Peoria, Illinois
Fort Wayne Medical Oncology and Hematology- South Office /ID# 259583, Fort Wayne, Indiana
University of Iowa Health Care /ID# 262132, Des Moines, Iowa
University of Louisville Hospital /ID# 260544, Louisville, Kentucky
Norton Cancer Institute - St. Matthews /ID# 261076, Louisville, Kentucky
New England Cancer Specialists - Westbrook /ID# 260672, Westbrook, Maine
University of Maryland, Baltimore /ID# 259538, Baltimore, Maryland
Center for Cancer and Blood Disorders-American Oncology Partners of Maryland /ID# 259476, Bethesda, Maryland
St. Luke's Hospital - Chesterfield /ID# 260489, Chesterfield, Missouri
Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana /ID# 260006, Billings, Montana
Nebraska Cancer Specialists (NCS) - Regional Cancer Center - St Francis Location /ID# 262506, Grand Island, Nebraska
NHO - Nebraska Hematology-Oncology /ID# 269692, Lincoln, Nebraska
Nebraska Cancer Specialists - Omaha - Wright Street /ID# 262505, Omaha, Nebraska
University of Nebraska Medical Center /ID# 261996, Omaha, Nebraska
University of New Mexico /ID# 261083, Albuquerque, New Mexico
Presbyterian Kaseman Hospital /ID# 262451, Albuquerque, New Mexico
Presbyterian Rust Medical Center /ID# 262447, Rio Rancho, New Mexico
New York Oncology Hematology - Albany Cancer Center /ID# 261814, Albany, New York
NYU Langone Hospital - Long Island /ID# 265531, Mineola, New York
NYU Langone Medical Center /ID# 264518, New York, New York
Icahn School of Medicine at Mount Sinai /ID# 259595, New York, New York
New York Oncology Hematology /ID# 270208, Troy, New York
Clinical Research Alliance, Inc. /ID# 261078, Westbury, New York
Novant Health Presbyterian Medical Center /ID# 259740, Charlotte, North Carolina
Novant Health Forsyth Medical Center /ID# 259741, Winston-Salem, North Carolina
Oncology Hematology Care, Inc - Blue Ash /ID# 261204, Cincinnati, Ohio
Taylor Cancer Research Center /ID# 260488, Maumee, Ohio
Oncology Associates of Oregon, P.C. /ID# 261816, Eugene, Oregon
MUSC Hollings Cancer Center /ID# 259604, Charleston, South Carolina
Prisma Health /ID# 259602, Greenville, South Carolina
Texas Oncology - Austin Midtown /ID# 261208, Austin, Texas
Texas Oncology- Baylor Charles A. Sammons Cancer Center /ID# 261206, Dallas, Texas
MD Anderson Cancer Center /ID# 260984, Houston, Texas
Oncology Consultants /ID# 268390, Houston, Texas
Joe Arrington Cancer Research /ID# 260382, Lubbock, Texas
Intermountain Healthcare LDS Hospital /ID# 259759, Salt Lake City, Utah
Virginia Cancer Specialists - Fairfax /ID# 261205, Fairfax, Virginia
Oncology and Hematology Associates of Southwest Virginia /ID# 261592, Roanoke, Virginia
Swedish Cancer Institute - Edmonds /ID# 266356, Edmonds, Washington
Swedish Cancer Institute - Issaquah /ID# 266358, Issaquah, Washington
Vista Oncology - East Olympia /ID# 261360, Olympia, Washington
Virginia Mason Hospital & Medical Center /ID# 260549, Seattle, Washington
Swedish Cancer Institute /ID# 260370, Seattle, Washington
Northwest Medical Specialties - Tacoma /ID# 262133, Tacoma, Washington
Royal Prince Alfred Hospital /ID# 259320, Camperdown, New South Wales
Liverpool Hospital /ID# 259321, Liverpool, New South Wales
Peter MacCallum Cancer Center /ID# 260431, Melbourne, New South Wales
Westmead Hospital /ID# 261465, Westmead, New South Wales
Townsville University Hospital /ID# 259323, Douglas, Queensland
Royal Brisbane and Women's Hospital /ID# 259326, Herston, Queensland
Princess Alexandra Hospital /ID# 259329, Woolloongabba, Queensland
Peninsula Private Hospital /ID# 259325, Frankston, Victoria
Fiona Stanley Hospital /ID# 259324, Murdoch, Western Australia
Royal Perth Hospital /ID# 259319, Perth, Western Australia
Algemeen Ziekenhuis klina /ID# 260324, Brasschaat, Antwerpen
Uza /Id# 260319, Edegem, Antwerpen
Cliniques Universitaires UCL Saint-Luc /ID# 260311, Bruxelles, Bruxelles-Capitale
Groupe Sante CHC - Clinique du MontLegia /ID# 260325, Liège, Liege
UZ Gent /ID# 260312, Gent, Oost-Vlaanderen
Universitair Ziekenhuis Leuven /ID# 260304, Leuven, Vlaams-Brabant
AZ-Delta /ID# 260313, Roeselare, West-Vlaanderen
UMHAT Dr Georgi Stranski EAD /ID# 260763, Pleven, Not set
Acibadem City Clinic Tokuda University Hospital EAD /ID# 260685, Sofia, Not set
UMHAT Sveti Ivan Rilski /ID# 259277, Sofia, Not set
SHAT Hematologic Diseases /ID# 260457, Sofia, Not set
Victoria Hospital /ID# 260770, London, Ontario
The Ottawa Hospital - General Campus /ID# 264470, Ottawa, Ontario
CSSS Alphonse-Desjardins, CHAU de Levis /ID# 260527, Levis, Quebec
Disc_Royal Victoria Hospital / McGill University Health Centre /ID# 261075, Montreal, Quebec
Centre Hospitalier de l'Université de Montréal (CHUM) /ID# 260617, Montréal, Quebec
Peking University First Hospital /ID# 259816, Beijing, Beijing
Peking University Third Hospital /ID# 259806, Beijing, Beijing
The First Affiliated Hospital of Xiamen University /ID# 260014, Xiamen, Fujian
Sun Yat-Sen University Cancer Center /ID# 260478, Guangzhou, Guangdong
Guangdong Provincial People's Hospital /ID# 260446, Guangzhou, Guangdong
Zhujiang Hospital of Southern Medical University /ID# 260558, Guangzhou, Guangdong
Nanfang Hospital of Southern Medical University /ID# 260795, Guangzhou, Guangdong
Shenzhen People's Hospital /ID# 260137, Shenzhen, Guangdong
Affiliated Cancer Hospital of Guangxi Medical University /ID# 260537, Nanning, Guangxi
People's Hospital of Henan Province /ID# 259619, Zhengzhou, Henan
Henan Cancer Hospital /ID# 259618, Zhengzhou, Henan
Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 259743, Wuhan, Hubei
Hubei Cancer Hospital /ID# 260506, Wuhan, Hubei
Hunan Cancer Hospital /ID# 260439, Changsha, Hunan
The First Affiliated Hospital of Soochow University /ID# 260507, Suzhou, Jiangsu
The First Affiliated Hospital of Nanchang University /ID# 260556, Nanchang, Jiangxi
Jiangxi Provincial Cancer Hospital /ID# 260559, Nanchang, Jiangxi
The First Hospital of China Medical University /ID# 260217, Shenyang, Liaoning
Shandong Cancer Hospital /ID# 260808, Jinan, Shandong
Fudan University Cancer Hospital /ID# 260564, Shanghai, Shanghai
West China Hospital, Sichuan University /ID# 260015, Chengdu, Sichuan
Tianjin Cancer Hospital /ID# 259807, Tianjin, Tianjin
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 259616, Tianjin, Tianjin
The Affiliated Cancer Hospital of Xinjiang Medical University /ID# 260644, Urumqi, Xinjiang
Yunnan Cancer Hospital /ID# 260645, Kunming, Yunnan
The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 259744, Hangzhou, Zhejiang
Zhejiang Cancer hospital /ID# 259742, Hangzhou, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University /ID# 260566, Wenzhou, Zhejiang
Clinical Hospital Dubrava /ID# 260452, Zagreb, Grad Zagreb
Klinicka bolnica Merkur /ID# 260393, Zagreb, Grad Zagreb
Klinicki bolnicki centar Sestre milosrdnice /ID# 260456, Zagreb, Grad Zagreb
Klinicki bolnicki centar Zagreb /ID# 260364, Zagreb, Grad Zagreb
Klinicki bolnicki centar Rijeka /ID# 260455, Rijeka, Primorsko-goranska Zupanija
Klinicki Bolnicki Centar (KBC) Split /ID# 260454, Split, Splitsko-dalmatinska Zupanija
Zadar General Hospital /ID# 260837, Zadar, Not set
Fakultní nemocnice Hradec Králové - Sokolská /ID# 260560, Hradec Králové, Hradec Kralove
Fakultni nemocnice Kralovske Vinohrady /ID# 260572, Praha, Not set
Regionshospitalet Godstrup /ID# 260778, Herning, Midtjylland
Roskilde Sygehus /ID# 260780, Roskilde, Sjælland
Odense University Hospital /ID# 260777, Odense, Syddanmark
Sygehus Lillebalt, Vejle /ID# 260781, Vejle, Syddanmark
CHU de CAEN - Hopital de la Cote de Nacre /ID# 260875, Caen, Calvados
CHU Brest - Hôpital de la Cavale Blanche /ID# 260601, Brest, Finistere
Hopital Prive d'Antony /ID# 260598, Antony, Ile-de-France
Hopital Prive du Confluent /ID# 260596, Nantes CEDEX 2, Loire-Atlantique
Centre Hospitalier D'Avignon /ID# 260511, Avignon, Provence-Alpes-Cote-d Azur
HCL - Hopital Lyon Sud /ID# 260508, Pierre Benite CEDEX, Rhone
Centre Hospitalier du Mans /ID# 260510, Le Mans CEDEX 9, Sarthe
CH Libourne - Hopital Robert Boulin /ID# 261478, Libourne, Not set
Hôpital Saint-Louis /ID# 260509, Paris, Not set
Clinique Sainte-Anne /ID# 261528, Strasbourg, Not set
Staedtisches Klinikum Karlsruhe /ID# 260348, Karlsruhe, Baden-Wuerttemberg
Universitaetsklinikum Frankfurt /ID# 260388, Frankfurt am Main, Hessen
Klinikum Kassel /ID# 260432, Kassel, Hessen
St.-Antonius-Hospital /ID# 260520, Eschweiler, Nordrhein-Westfalen
Klinikum Ludwigshafen /ID# 260688, Ludwigshafen am Rhein, Rheinland-Pfalz
Otto-von-Guericke-Universitaet /ID# 260425, Magdeburg, Sachsen-Anhalt
Olympion General Clinic /ID# 262395, Patras, Achaia
General Hospital of Athens Laiko /ID# 259708, Athens, Attiki
University General Hospital Attikon /ID# 260855, Athens, Attiki
General University Hospital of Alexandroupolis /ID# 260858, Alexandroupolis, Not set
General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 259709, Athens, Not set
Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz /ID# 260051, Gyor, Gyor-Moson-Sopron
Tolna Varmegyei Balassa Janos Korhaz /ID# 260048, Szekszard, Tolna
Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 260050, Szombathely, Vas
Orszagos Onkologiai Intezet /ID# 260052, Budapest, Not set
Soroka University Medical Center /ID# 259937, Be'er Sheva, HaDarom
HaEmek Medical Center /ID# 259936, Afula, Haifa
Meir Medical Center /ID# 259938, Kfar Saba, HaMerkaz
The Chaim Sheba Medical Center /ID# 259934, Ramat Gan, Tel-Aviv
Tel Aviv Sourasky Medical Center /ID# 259933, Tel Aviv, Tel-Aviv
Hadassah /ID# 259935, Jerusalem, Yerushalayim
Rabin Medical Center /ID# 268328, Petah Tikva, Not set
IRCCS Istituto Clinico Humanitas /ID# 260887, Rozzano, Lombardia
Istituto di Candiolo Fondazione del Piemonte per l'Oncologia IRCCS /ID# 260889, Candiolo, Torino
IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 260886, Bologna, Not set
Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello /ID# 260888, Palermo, Not set
AUSL di Reggio Emilia - Arcispedale Santa Maria Nuova /ID# 260744, Reggio Emilia, Not set
Fondazione Policlinico Universitario Campus Bio-Medico /ID# 260891, Roma, Not set
Fujita Health University Hospital /ID# 264679, Toyoake, Aichi
Matsuyama Red Cross Hospital /ID# 266426, Matsuyama-shi, Ehime
University of Fukui Hospital /ID# 265680, Yoshida-gun, Fukui
National Hospital Organization Kyushu Cancer Center /ID# 265960, Fukuoka-shi, Fukuoka
Kyushu University Hospital /ID# 267861, Fukuoka-shi, Fukuoka
Fukushima Medical University Hospital /ID# 264994, Fukushima-shi, Fukushima
Chugoku Central Hospital /ID# 266520, Fukuyama, Hiroshima
Sapporo Medical University Hospital /ID# 265031, Sapporo, Hokkaido
Kobe City Medical Center General Hospital /ID# 266379, Kobe-shi, Hyogo
Hitachi General Hospital /ID# 265676, Hitachi-shi, Ibaraki
Kitasato University Hospital /ID# 264675, Sagamihara-shi, Kanagawa
Kanagawa Cancer Center /ID# 265497, Yokohama-shi, Kanagawa
Okayama University Hospital /ID# 267135, Okayama-shi, Okayama
Kansai Medical University Hirakata Hospital /ID# 266019, Hirakata-shi, Osaka
Kindai University Hospital /ID# 265038, Osaka sayama-shi, Osaka
Tokyo Metropolitan Komagome Hospital /ID# 267692, Bunkyo ku, Tokyo
The University of Tokyo Hospital /ID# 266422, Bunkyo-ku, Tokyo
Yamaguchi University Hospital /ID# 265619, Ube, Yamaguchi
University of Yamanashi Hospital /ID# 264677, Chuo-shi, Yamanashi
Aomori Prefectural Central Hospital /ID# 265692, Aomori, Not set
Chiba Cancer Center /ID# 267316, Chiba, Not set
Seoul National University Bundang Hospital /ID# 260009, Seongnam-si, Gyeonggido
Seoul National University Hospital /ID# 260007, Seoul, Seoul Teugbyeolsi
Asan Medical Center /ID# 260010, Seoul, Seoul Teugbyeolsi
Samsung Medical Center /ID# 260008, Seoul, Seoul Teugbyeolsi
Bravis Ziekenhuis /ID# 259055, Bergen op Zoom, Noord-Brabant
Elisabeth Tweesteden Ziekenhuis /ID# 261239, Tilburg, Noord-Brabant
Olvg /Id# 259543, Amsterdam, Noord-Holland
St. Antonius Ziekenhuis /ID# 259053, Nieuwegein, Utrecht
HagaZiekenhuis /ID# 261220, Den Haag, Zuid-Holland
Leids Universitair Medisch Centrum /ID# 259049, Leiden, Zuid-Holland
Franciscus Gasthuis & Vlietland, Locatie Gasthuis /ID# 259052, Rotterdam, Zuid-Holland
Rijnstate /ID# 261219, Arnhem, Not set
Universitair Medisch Centrum Groningen /ID# 259051, Groningen, Not set
Auckland City Hospital /ID# 259330, Grafton, Auckland
North Shore Hospital /ID# 260824, Takapuna, Auckland
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopern /ID# 260633, Lodz, Lodzkie
Pratia MCM Krakow /ID# 260075, Krakow, Malopolskie
Narodowy Instytut Onkologii im. M. Sklodowskiej /ID# 260861, Warszawa, Mazowieckie
Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej /ID# 260170, Kielce, Swietokrzyskie
Fundacao Champalimaud /ID# 259652, Lisbon, Lisboa
Unidade Local de Saude de Gaia/Espinho, EPE /ID# 259655, Vila Nova de Gaia, Porto
Unidade Local de Saude de Santa Maria, EPE /ID# 259650, Lisboa, Not set
Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE /ID# 259649, Porto, Not set
Pan American Center for Oncology Trials, LLC /ID# 260265, Rio Piedras, Not set
Auxilio Mutuo Cancer Center /ID# 260262, San Juan, Not set
Fundeni Clinical Institute /ID# 260296, Bucharest, Bucuresti
Institutul Oncologic Prof Dr. Ion Chiricuta Cluj Napoca /ID# 259704, Cluj-Napoca, Cluj
Institutul Regional de Oncologie /ID# 259697, Jassi, Iasi
Spitalul Clinic Coltea /ID# 259699, Bucharest, Not set
Clinical Hospital Center Zvezdara /ID# 260900, Belgrade, Beograd
University Clinical Center Serbia /ID# 259271, Belgrade, Beograd
University Clinical Center Kragujevac /ID# 259274, Kragujevac, Sumadijski Okrug
Institute for Oncology of Vojvodina /ID# 260223, Sremska Kamenica, Vojvodina
University Clinical Center Vojvodina /ID# 259272, Novi Sad, Not set
Narodny onkologicky ustav /ID# 260638, Bratislava, Bratislavsky Kraj
Univerzitna nemocnica Martin /ID# 260631, Martin, Zilinsky Kraj
Alberts Cellular Therapy /ID# 260514, Pretoria, Gauteng
Haemalife Inc. /ID# 260513, Kuilsrivier, Western Cape
Instituto Catalan de Oncologia (ICO) Badalona /ID# 260495, Badalona, Barcelona
Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 261439, L'Hospitalet de Llobregat, Barcelona
Hospital Universitario Marques de Valdecilla /ID# 260497, Santander, Cantabria
Clinica Universidad de Navarra - Pamplona /ID# 260496, Pamplona, Navarra
Hospital Universitario Vall d'Hebron /ID# 260490, Barcelona, Not set
Hospital Clinic de Barcelona /ID# 260492, Barcelona, Not set
Hospital Santa Creu i Sant Pau /ID# 260498, Barcelona, Not set
Hospital San Pedro de Alcantara /ID# 260502, Caceres, Not set
CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 261512, Madrid, Not set
MD Anderson Madrid /ID# 260500, Madrid, Not set
Hospital Universitario de Salamanca /ID# 260491, Salamanca, Not set
Sodra Alvsborgs sjukhus /ID# 261168, Boras, Vastra Gotalands Lan
National Taiwan University Hospital /ID# 260341, Taipei City, Taipei
China Medical University Hospital /ID# 260357, Taichung, Not set
Taichung Veterans General Hospital /ID# 260361, Taichung, Not set
National Cheng Kung University Hospital /ID# 260363, Tainan, Not set
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 259804, Istanbul, Not set
Ege Universitesi Tip Fakultesi /ID# 259803, Izmir, Not set
Kocaeli University Med Faculty /ID# 259717, Kocaeli, Not set
Ondokuz Mayis Universitesi /ID# 259713, Samsun, Not set
Istanbul Florence Nightingale Hospital /ID# 271291, Şişli, Not set
Derriford Hospital and the Royal Eye Infirmary /ID# 262671, Plymouth, Devon
Hammersmith Hospital /ID# 261124, London, England
Queen Alexandra Hospital /ID# 269708, Portsmouth, Hampshire
Leeds Teaching Hospitals NHS Trust /ID# 260466, Leeds, West Yorkshire
The Christie Hospital /ID# 260463, Manchester, Not set
The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 260792, Newcastle upon Tyne, Not set
Conditions: Follicular Lymphoma (FL)
Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating stage III or stage IV Hodgkin's lymphoma.
PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients who have stage III or stage IV Hodgkin's lymphoma.
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating stage III or stage IV Hodgkin's lymphoma.
PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens in treating patients who have stage III or stage IV Hodgkin's lymphoma. Read Less
Gender:
ALL
Ages:
Between 16 years and 60 years
Trial Updated:
08/04/2025
Locations: Canberra Hospital, Garran, Australian Capital Territory +139 locations
Canberra Hospital, Garran, Australian Capital Territory
Nepean Cancer Care Centre at Nepean Hospital, Kingswood, New South Wales
Westmead Institute for Cancer Research at Westmead Hospital, Westmead, New South Wales
Princess Alexandra Hospital, Brisbane, Queensland
Peter MacCallum Cancer Centre, East Melbourne, Victoria
St. Vincent's Hospital - Melbourne, Fitzroy, Victoria
Royal Perth Hospital, Perth, Western Australia
Ziekenhuis Netwerk Antwerpen Middelheim, Antwerp, Not set
AZ Sint-Jan, Brugge, Not set
Institut Jules Bordet, Brussels, Not set
Hopital Universitaire Erasme, Brussels, Not set
Cliniques Universitaires Saint-Luc, Brussels, Not set
Centre Hospitalier Universitaire Brugmann, Brussels, Not set
Centre Hospitalier Notre Dame - Reine Fabiola, Charleroi, Not set
Universitair Ziekenhuis Antwerpen, Edegem, Not set
Algemeen Ziekenhuis Sint Lucas, Ghent, Not set
Hopital de Jolimont, Haine Saint Paul, Not set
U.Z. Gasthuisberg, Leuven, Not set
Centre Hospitalier Regional de la Citadelle, Liege, Not set
H. Hartziekenhuis - Roeselaere, Roeselare, Not set
Clinique Universitaire De Mont-Godinne, Yvoir, Not set
Tom Baker Cancer Centre - Calgary, Calgary, Alberta
Cross Cancer Institute at University of Alberta, Edmonton, Alberta
CancerCare Manitoba, Winnipeg, Manitoba
Centre Hospitalier De Dunkerque - CHD, Winnipeg, Manitoba
Moncton Hospital, Moncton, New Brunswick
Doctor H. Bliss Murphy Cancer Centre, St. Johns, Newfoundland and Labrador
Nova Scotia Cancer Centre, Halifax, Nova Scotia
Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario
London Regional Cancer Program at London Health Sciences Centre, London, Ontario
Ottawa Hospital Regional Cancer Centre - General Campus, Ottawa, Ontario
Northeastern Ontario Regional Cancer Centre, Sudbury, Ontario
Edmond Odette Cancer Centre at Sunnybrook, Toronto, Ontario
Princess Margaret Hospital, Toronto, Ontario
Windsor Regional Cancer Centre at Windsor Regional Hospital, Windsor, Ontario
Hopital Charles Lemoyne, Greenfield Park, Quebec
Maisonneuve-Rosemont Hospital, Montreal, Quebec
Hopital Notre-Dame du CHUM, Montreal, Quebec
CHUM - Hotel Dieu Hospital, Montreal, Quebec
McGill Cancer Centre at McGill University, Montreal, Quebec
Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec
Hopital du Saint-Sacrement - Quebec, Quebec City, Quebec
Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon, Saskatchewan
University Hospital Rebro, Zagreb, Not set
Thomayer's University Hospital, Prague, Not set
Centre Hospitalier d'Annecy, Annecy, Not set
Centre Hospitalier de la Cote Basque, Bayonne, Not set
Centre Hospitalier Regional de Besancon - Hopital Jean Minjoz, Besancon, Not set
Institut Bergonie, Bordeaux, Not set
Polyclinique Bordeaux Nord Aquitaine, Boucher, Not set
C.H. Bourg En Bresse, Bourg En Bresse, Not set
CHU de Caen, Caen, Not set
Polyclinique Du Parc, Caen, Not set
Centre Regional Francois Baclesse, Caen, Not set
Centre Hospitalier Regional de Chambery, Chambery, Not set
Hopital d'Instruction des Armees Percy, Clamart, Not set
Hopital Antoine Beclere, Clamart, Not set
CHR Clermont Ferrand, Hotel Dieu, Clermont-Ferrand, Not set
Hopital Louis Pasteur, Colmar, Not set
Centre Hospitalier Sud Francilien - Site Corbeil, Corbeil, Not set
Centre Hospitalier Universitaire Henri Mondor, Creteil, Not set
Hopital Du Bocage, Dijon, Not set
Institut Prive de Cancerologie, Grenoble, Not set
Hopital Andre Mignot, Le Chesnay, Not set
Hopital Saint Antoine Lille, Lille, Not set
Centre Hospitalier Regional et Universitaire de Lille, Lille, Not set
Centre Hospital Regional Universitaire de Limoges, Limoges, Not set
Centre Leon Berard, Lyon, Not set
Hopital Edouard Herriot - Lyon, Lyon, Not set
Marseille Institute of Cancer - Institut J. Paoli and I. Calmettes, Marseille, Not set
Centre Hospitalier de Meaux, Meaux, Not set
Centre Hospitalier Marc Jacquet, Melun, Not set
Hopital Notre-Dame de Bon Secours, Metz, Not set
Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle, Montpellier, Not set
Centre Hospitalier de Mulhouse, Mulhouse, Not set
Centre Antoine Lacassagne, Nice, Not set
Hopital de l'Archet CHU de Nice, Nice, Not set
Hotel Dieu de Paris, Paris, Not set
Institut Curie Hopital, Paris, Not set
Hopital Saint-Louis, Paris, Not set
Hopital Saint Antoine, Paris, Not set
CHU Pitie-Salpetriere, Paris, Not set
Hopital Cochin, Paris, Not set
Hopital Necker, Paris, Not set
Hopital Haut Leveque, Pessac, Not set
Centre Hospitalier Lyon Sud, Pierre Benite, Not set
Hopital Rene Dubos, Pontoise, Not set
Institut Jean Godinot, Reims, Not set
Hopital Sud, Rennes, Not set
Centre Henri Becquerel, Rouen, Not set
Centre Rene Huguenin, Saint Cloud, Not set
CHU Sainte-Etienne - Hopital Bellevue, Saint Etienne, Not set
Hopital de Saint Germain-en-Laye, Saint Germain-en-Laye, Not set
Hopital Universitaire Hautepierre, Strasbourg, Not set
Hopital Foch, Suresnes, Not set
Centre Hospitalier Valence, Valence, Not set
Centre Hospitalier de Valenciennes, Valenciennes, Not set
CHU de Nancy - Hopitaux de Brabois, Vandoeuvre-Les-Nancy, Not set
Hopital Paul Brousse, Villejuif, Not set
Institut Gustave Roussy, Villejuif, Not set
National Institute of Oncology, Budapest, Not set
HagaZiekenhuis - Locatie Leyenburg, 's-Gravenhage, Not set
Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, Not set
Meander Medisch Centrum, Amersfoort, Not set
Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Not set
Onze Lieve Vrouwe Gasthuis, Amsterdam, Not set
Academisch Medisch Centrum at University of Amsterdam, Amsterdam, Not set
Reinier de Graaf Group - Delft, Delft, Not set
Medisch Spectrum Twente, Enschede, Not set
University Medical Center Groningen, Groningen, Not set
Atrium Medical Centre - Heerlen, Heerlen, Not set
Leiden University Medical Center, Leiden, Not set
Academisch Ziekenhuis Maastricht, Maastricht, Not set
Universitair Medisch Centrum St. Radboud - Nijmegen, Nijmegen, Not set
Saint Laurentius Ziekenhuis, Roermond, Not set
Daniel Den Hoed Cancer Center at Erasmus Medical Center, Rotterdam, Not set
University Medical Center Utrecht, Utrecht, Not set
Auckland City Hospital, Auckland, Not set
Waikato Hospital, Hamilton, Not set
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology - Warsaw, Warsaw, Not set
Hospital de la Santa Cruz i Sant Pau, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital Universitari Germans Trias i Pujol, Barcelona, Not set
Sahlgrenska University Hospital, Gothenburg (Goteborg), Not set
University Hospital of Linkoping, Linkoping, Not set
Lund University Hospital, Lund, Not set
Karolinska University Hospital - Huddinge, Stockholm, Not set
Umea Universitet, Umea, Not set
Uppsala University Hospital, Uppsala, Not set
Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust, Birmingham, England
Raigmore Hospital, Birmingham, England
Kent and Canterbury Hospital, Canterbury, England
Hull Royal Infirmary, Hull, England
Kettering General Hosptial, Kettering, England
Leicester Royal Infirmary, Leicester, England
Middlesex Hospital, London, England
Mount Vernon Cancer Centre at Mount Vernon Hospital, Northwood, England
Nottingham City Hospital NHS Trust, Nottingham, England
Cancer Research Centre at Weston Park Hospital, Sheffield, England
Staffordshire General Hospital, Stafford, England
Conditions: Lymphoma
An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma
Recruiting
The purpose of this study is to compare the efficacy and safety of glofitamab in combination with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone (Pola-R-CHP) vs Pola-R-CHP in participants with previously untreated CD20-positive large B-cell lymphoma (LBCL).
The purpose of this study is to compare the efficacy and safety of glofitamab in combination with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone (Pola-R-CHP) vs Pola-R-CHP in participants with previously untreated CD20-positive large B-cell lymphoma (LBCL). Read Less
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/01/2025
Locations: Alaska Oncology & Hematology, LLC, Anchorage, Alaska +273 locations
Alaska Oncology & Hematology, LLC, Anchorage, Alaska
Kaiser Permanente - Anaheim (E. La Palma), Anaheim, California
University of California, San Francisco-Fresno, Clovis, California
City of Hope National Medical Center, Duarte, California
City of Hope - Lennar Foundation Cancer Center, Irvine, California
Scripps Clinic Torrey Pines, La Jolla, California
Valkyrie Clinical Trials, Los Angeles, California
UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California
Kaiser Permanente - Oakland, Oakland, California
Kaiser Permanente - Roseville, Roseville, California
Kaiser Permanente - San Francisco (2238 Geary), San Francisco, California
Kaiser Permanente - Santa Clara, Santa Clara, California
Stanford Univ School of Med, Stanford, California
Kaiser Permanente Medical Ctr, Vallejo, California
Kaiser Permanente - Walnut Creek, Walnut Creek, California
University of Colorado Cancer Center, Aurora, Colorado
Rocky Mountain Cancer Center - Denver, Littleton, Colorado
Yale University School Of Medicine, New Haven, Connecticut
Medstar Franklin Square Medical Center, Washington, District of Columbia
Miami Cancer Institute of Baptist Health, Inc., Miami, Florida
Memorial Cancer Institute at Memorial West, Pembroke Pines, Florida
Hawaii Cancer Care, Honolulu, Hawaii
Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois
NorthShore Center for Advanced Imaging, Evanston, Illinois
Illinois Cancer Care, Peoria, Illinois
Springfield Clinic, Springfield, Illinois
University of Iowa, Iowa City, Iowa
Ascension Via Christi Research, Wichita, Kansas
Ochsner Medical Center, New Orleans, Louisiana
Louisiana State University Health Sciences Center, Shreveport, Louisiana
Massachusetts General Hospital, Boston, Massachusetts
Dana Farber Cancer Institute, Boston, Massachusetts
Boston Medical Center, Boston, Massachusetts
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Health System, Novi, Michigan
M Health Fairview University of Minnesota Medical Center, Minneapolis, Minnesota
St. Luke's Hospital, Chesterfield, Missouri
University of Missouri Health Care, Columbia, Missouri
Washington University School of Medicine, Saint Louis, Missouri
St. Vincent Frontier Cancer Center, Billings, Montana
University of Nebraska Medical Center, Omaha, Nebraska
MSKCC at Basking Ridge, Basking Ridge, New Jersey
Astera Cancer Care East Brunswick, East Brunswick, New Jersey
MSK Monmouth, Middletown, New Jersey
MSK Bergen, Montvale, New Jersey
Montefiore Medical Center - Montefiore Medical Park, Bronx, New York
Montefiore Medical Center, Bronx, New York
New York Cancer & Blood Specialists, Bronx, New York
NYU Langone Hospital?Brooklyn, Brooklyn, New York
MSK Commack, Commack, New York
Memorial Sloan Kettering Cancer Center, Harrison, New York
NYU Long Island Hospital, Mineola, New York
New York Cancer and Blood Specialists - New Hyde Park, New Hyde Park, New York
New York University Medical Center PRIME, New York, New York
Memorial Sloan Kettering Cancer Center David H Koch Center for Cancer Care, New York, New York
Weill Cornell Medical College-New York Presbyterian Hospital, New York, New York
New York Cancer and Blood Specialists-Central Park Hematology & Oncology, New York, New York
University of Rochester Medical Center, Rochester, New York
North Shore Hematology Oncology Association PC, Shirley, New York
MSK Nassau, Uniondale, New York
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Levine Cancer Institute, Charlotte, North Carolina
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Oncology Hematology Care Inc - Cincinnati - USOR, Cincinnati, Ohio
Willamette Valley Cancer Insitute and Research Center, Springfield, Oregon
Kimmel Cancer Center Thomas Jefferson University, Philadelphia, Pennsylvania
Fox Chase Cancer Center, Philadelphia, Pennsylvania
West Penn Hospital, Pittsburgh, Pennsylvania
Avera Cancer Institute, Sioux Falls, South Dakota
Greco-Hainesworth Tennessee Oncology Centers for Research, Chattanooga, Tennessee
West Cancer Center & Research Institute, Germantown, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
Tennessee Oncology, Nashville, Tennessee
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Texas Oncology, Fort Worth, Texas
Harris Health System Smith Clinic, Houston, Texas
O'Quinn Medical Tower at McNair Campus, Houston, Texas
USOR - Texas Oncology - San Antonio Northeast, San Antonio, Texas
University of Vermont, Burlington, Vermont
Virginia Cancer Specialists, Fairfax, Virginia
Virginia Oncology Associates, Newport News, Virginia
Swedish Cancer Institute - Edmonds Campus, Edmonds, Washington
Swedish Cancer Institute - Issaquah, Issaquah, Washington
Swedish Medical Center, Seattle, Washington
University of Washington - Seattle Cancer Care Alliance, Seattle, Washington
West Virginia University, Morgantown, West Virginia
Univ of Wisconsin Hosp & Clin, Madison, Wisconsin
Instituto Alexander Fleming, Buenos Aires, Not set
FUNDALEU, Buenos Aires, Not set
Hospital Aleman de Buenos Aires, Buenos Aires, Not set
Sanatorio Allende, Cordoba, Not set
Hospital Austral, Pilar, Not set
Concord Repatriation General Hospital, Concord, New South Wales
Prince of Wales Hospital- Department of Hematology, Randwick, New South Wales
Townsville Hospital, Douglas, Queensland
Princess Alexandra Hospital Woolloongabba, Woolloongabba, Queensland
Flinders Medical Centre, Bedford Park, South Australia
Royal Hobart Hospital, Hobart, Tasmania
Eastern Health, Box Hill, Victoria
St Vincent's Hospital Melbourne, Fitzroy, Victoria
Barwon Health, Geelong, Victoria
Peter Maccallum Cancer Centre, Melbourne, Victoria
Sir Charles Gairdner Hospital, Nedlands, Western Australia
Institut Jules Bordet, Anderlecht, Not set
UZ Brussel, Brussel, Not set
UZ Antwerpen, Edegem, Not set
UZ Gent, Gent, Not set
AZ Groeninge, Kortrijk, Not set
CHU de Liège (Sart Tilman), Liège, Not set
Hospital Erasto Gaertner, Curitiba, Paraná
Instituto D'Or Pesquisa e Ensino, Sao Paulo, São Paulo
Hospital das Clinicas - FMUSP, Oncologia, Sao Paulo, São Paulo
Eastern Health - General Hospital, St. John's, Newfoundland and Labrador
Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia
Royal Victoria Regional Health Centre, Barrie, Ontario
William Osler Health Centre - Brampton Civic Hospital, Brampton, Ontario
The Ottawa Hospital - General Campus, Ottawa, Ontario
Health Sciences North, Sudbury, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec
CHA Hopital de I enfant-Jesus, Quebec City, Quebec
Centre Integre Universitaire de Sante et de Services Sociaux de la Mauricie-et-du-Centre-du-Quebec, Trois-rivieres, Quebec
Beijing Cancer Hospital, Beijing, Not set
Peking University Third Hospital, Beijing, Not set
The First Hospital of Jilin University, Changchun City, Not set
Hunan Cancer Hospital, Changsha CITY, Not set
West China Hospital, Sichuan University, Chengdu, Not set
Sichuan Provincial People's Hospital, Chengdu, Not set
Second Affiliated Hospital of Third Military Medical University, Chongqing, Not set
Fujian Cancer Hospital, Fuzhou, Not set
Southern Medical University Nanfang Hospital, Guangdong Province Guangzhou City, Not set
Sun yat-sen University Cancer Center, Guangzhou, Not set
Zhujiang Hospital, Southern Medical University, Guangzhou, Not set
Harbin Medical University Cancer Hospital, Harbin, Not set
Anhui Province Cancer Hospital, Hefei City, Not set
Shandong Cancer Hospital, Jinan, Not set
Jiangxi Cancer Hospital, Nanchang City, Not set
Jiangsu Cancer Hospital, Nanjing City, Not set
Guangxi Cancer Hospital of Guangxi Medical University, Nanning, Not set
Fudan University Shanghai Cancer Center, Shanghai City, Not set
Shengjing Hospital of China Medical University, Shenyang City, Not set
First Hospital of China Medical University, Shenyang, Not set
First Affiliated Hospital of Soochow University, Suzhou, Not set
Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences, Tianjin City, Not set
Tianjin Cancer Hospital, Tianjin, Not set
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, Not set
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, Not set
The First Affiliated Hospital of Xiamen University, Xiamen, Not set
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set
Aalborg Universitetshospital, Aalborg, Not set
Aarhus Universitetshospital Skejby, Aarhus N, Not set
Regionshospitalet Gødstrup, Herning, Not set
CHRU de Lille - Hopital Claude Huriez, Lille, Not set
Hospices Civils de Lyon, Lyon, Not set
Institut Paoli Calmettes, Marseille, Not set
CHU Montpellier, Montpellier, Not set
CHU de Nantes - Hotel Dieu, Nantes, Not set
CHU de Bordeaux, Pessac, Not set
CHU DE RENNES - CHU Pontchaillou, Rennes, Not set
Centre Henri Becquerel, Rouen, Not set
CHU Strasbourg Hpital Hautepierre, Strasbourg, Not set
IUCT Oncopole, Toulouse, Not set
Charité Universitätsmedizin Berlin, Berlin, Not set
Staedisches Klinikum Brandenburg, Brandenburg an der Havel, Not set
Klinikum Chemnitz gGmbH, Klinik f. Innere Medizin III, Chemnitz, Not set
Universitätsklinikum Düsseldorf, Düsseldorf, Not set
Universitätsklinikum Erlangen, Medizinische Klinik 5, Hämatologie und Internistische Onkologie, Erlangen, Not set
Universitätsklinikum Essen, Essen, Not set
Universitätsklinikum Frankfurt, Frankfurt, Not set
UKE Universitätsklinikum Hamburg-Eppendorf, Hamburg, Not set
Westpfalz-Klinikum GmbH, Kaiserslautern, Not set
Städtisches Krankenhaus Kiel GmbH, Kiel, Not set
Universitätsklinikum Köln, Koeln, Not set
Universitaetsklinikum Schleswig Holstein - Campus Luebeck, Luebeck, Not set
Otto von Guericke Uni Magdeburg Uniklinik, Magdeburg, Not set
Klinikum rechts der Isar der TU München, III. Medizinische Klinik, München, Not set
Universitätsklinikum Münster, Münster, Not set
Klinikum Ernst von Bergman, Potsdam, Not set
Universitaet Rostock, Zentrum Innere Medizin, Rostock, Not set
Klinikum Stuttgart Katharinenhospital, Stuttgart, Not set
Universitätsklinikum Ulm, Ulm, Not set
Universitätsklinikum Würzburg, Würzburg, Not set
Istituto Nazionale Tumori Irccs Fondazione g. Pascale, Napoli, Campania
Policlinico S.Orsola-Malpighi, Bologna, Emilia-Romagna
A.O. Universitaria Policlinico Di Modena, Modena, Emilia-Romagna
A.O. Universitaria S. Martino Di Genova, Genova, Liguria
Asst Papa Giovanni Xxiii, Bergamo, Lombardia
Fond. IRCCS Istituto Nazionale Tumori, Milano, Lombardia
Istituto Clinico Humanitas, Rozzano, Lombardia
A. O. U. Policlinico G. Rodolico, Catania, Sicilia
USL 4 di Prato - Nuovo Ospeale di Prato, Prato, Toscana
Ospedale San Bortolo, Vicenza, Veneto
Anjo Kosei Hospital, Aichi, Not set
Aichi Cancer Center, Aichi, Not set
Nagoya University Hospital, Aichi, Not set
Chiba Cancer Center, Chiba, Not set
National Cancer Center Hospital East, Chiba, Not set
National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set
Kyushu University Hospital, Fukuoka, Not set
Gifu University Hospital, Gifu, Not set
Hokkaido University Hospital, Hokkaido, Not set
Kobe City Medical Center General Hospital, Hyogo, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Tokai University Hospital, Kanagawa, Not set
University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set
Tohoku University Hospital, Miyagi, Not set
Okayama University Hospital, Okayama, Not set
Osaka Metropolitan University Hospital, Osaka, Not set
Kansai Medical University Hospital, Osaka, Not set
Kindai University Hospital, Osaka, Not set
Shimane University Hospital, Shimane, Not set
National Cancer Center Hospital, Tokyo, Not set
Komagome Hospital, Tokyo, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
Keio University Hospital, Tokyo, Not set
Yamagata University Hospital, Yamagata, Not set
Inje university Haeundae Paik Hospital, Busan, Not set
Pusan National University Hospital, Busan, Not set
Keimyung University Dongsan Medical Center, Daegu, Not set
Chungnam National University Hospital, Daejeon, Not set
National Cancer Center, Goyang-si, Not set
Chonnam National University Hwasun Hospital, Jeollanam-do, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul St Mary's Hospital, Seoul, Not set
Yeouido St. Mary's Hospital, Seoul, Not set
Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)
Inst. Nacional de Cancerologia, Mexico City, Mexico CITY (federal District)
Hospital General de Mexico, Mexico, Tlaxcala
Hospital de Especialidades Centro Medico Nacional La Raza, Mexico City, Not set
Szpital Specjalistyczny Podkarpacki O?rodek Onkologiczny, Brzozów, Not set
Uniwersyteckie Centrum Kliniczne, Gda?sk, Not set
Pratia Onkologia Katowice, Katowice, Not set
?wi?tokrzyskie Centrum Onkologii SPZOZ, Kielce, Not set
PRATIA MCM Kraków, Kraków, Not set
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu, Wroc?aw, Not set
Auxilio Mutuo Cancer Center, San Juan, Not set
Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, LA Coruna
Hospital Quiron de Madrid, Pozuelo de Alarcon, Madrid
Clinica Universitaria de Navarra, Pamplona, Navarra
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
Clinica Universidad de Navarra Madrid, Madrid, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
Universitaetsspital Basel, Basel, Not set
Chang Gung Medical Foundation - Chai Yi, Chai Yi, Not set
Chang Gung Medical Foundation - Kaohsiung;Oncology, Kaoisung, Not set
E-Da Cancer Hospital, Kaoshiung, Not set
China Medical University Hospital, Taichung, Not set
Chi-Mei Hospital, Liouying, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
Abdurrahman Yurtarslan Onkoloji Training and Research Hospital, Ankara, Not set
Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi, Ankara, Not set
Istanbul VKV American Hospital, Istanbul, Not set
Marmara University Pendik Training and Research Hospital, Istanbul, Not set
Kocaeli Univesity Medical Faculty, Izmit, Not set
Barnet Hospital, Barnet, Not set
Blackpool Victoria Hospital, Blackpool, Not set
East Kent Hospitals University NHS Foundation Trust, Canterbury, Not set
Royal Devon and Exeter Hospital, Exeter, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
Leeds Teaching Hosp NHS Trust, Leeds, Not set
Leicester Royal Infirmary, Leicester, Not set
University College London Hospitals NHS Foundation Trust - University College Hospital, London, Not set
Guy'S Hospital, London, Not set
Newcastle University, Newcastle, Not set
Nottingham University Hospitals NHS Trust, Nottingham, Not set
Churchill Hospital - Oxford Cancer & Haematology Centre, Oxford, Not set
Southampton General Hospital, Southampton, Not set
Conditions: Large B-Cell Lymphoma
Acalabrutinib in Combination With R-CHOP for Previously Untreated Diffuse Large B-cell Lymphoma (DLBCL)
Active Not Recruiting
This study evaluates the addition of Acalabrutinib to current standard therapy of Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone (R-CHOP) for patients with previously untreated CD20 positive Diffuse Large B-cell Lymphoma (DLBCL) requiring full course chemoimmunotherapy.
All patients will receive one cycle of R-CHOP. Two thirds of patients (Arm B) will go on to receive a further 5 cycles (every 21 days) of R-CHOP with Acalabrutinib. Acalabrutinib will be taken orally twic... Read More
This study evaluates the addition of Acalabrutinib to current standard therapy of Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone (R-CHOP) for patients with previously untreated CD20 positive Diffuse Large B-cell Lymphoma (DLBCL) requiring full course chemoimmunotherapy.
All patients will receive one cycle of R-CHOP. Two thirds of patients (Arm B) will go on to receive a further 5 cycles (every 21 days) of R-CHOP with Acalabrutinib. Acalabrutinib will be taken orally twice daily continuously in 21 day cycles.
One third of patients (Arm A) will continue with 5 cycles of R-CHOP.
Patients will be followed up initially for 24 months and then for disease status and survival until 114 progression events have been observed. Read Less
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/31/2025
Locations: Colchester General Hospital, Colchester, Essex +32 locations
Colchester General Hospital, Colchester, Essex
East Kent Hospitals NHS Foundation Trust, Canterbury, Kent
Monklands Hospital, Airdrie, Not set
Victoria Hospital, Blackpool, Not set
University Hospital Dorset NHS Foundation Trust (Bournemouth and Poole Hospitals), Bournemouth, Not set
Queens Hospital, Burton On Trent, Not set
Addenbrooke's Hospital, Cambridge, Not set
Royal Derby Hospital, Derby, Not set
Royal Devon and Exeter Hospital, Exeter, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
Ipswich Hospital, Ipswich, Not set
St James Hospital, Leeds, Not set
Leicester Royal Infirmary, Leicester, Not set
Chase Farm and Barnet Hospitals, London, Not set
Lewisham and Greenwich NHS Trust, London, Not set
University College London Hospital, London, Not set
Maidstone Hospital, Maidstone, Not set
The Christie Hospital, Manchester, Not set
Milton Keynes University Hospital, Milton Keynes, Not set
Freeman Hospital, Newcastle, Not set
Norfolk and Norwich University Hospital, Norwich, Not set
Nottingham City Hospital, Nottingham, Not set
Royal Oldham Hospital, Oldham, Not set
Churchill Hospital, Oxford, Not set
Derriford Hospital, Plymouth, Not set
Queen Alexandra Hospital, Portsmouth, Not set
Queen's Hospital, Romford, Not set
Southampton General Hospital, Southampton, Not set
Royal Stoke University Hospital, Stoke-on-Trent, Not set
Singleton Hospital, Swansea, Not set
Torbay Hospital, Torquay, Not set
Royal Cornwall Hospital, Truro, Not set
Worthing and St Richards Hospitals, Worthing, Not set
Conditions: Diffuse Large B Cell Lymphoma
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
Recruiting
The study is a global, multi-center safety and efficacy trial of epcoritamab, an antibody also known as EPKINLY™ and GEN3013 (DuoBody®-CD3xCD20). Epcoritamab will be tested either in
Relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) as:
* Monotherapy, or
* Combination therapy:
* epcoritamab + venetoclax
* epcoritamab + pirtobrutinib
In Non-United States (US) Participants Only: Treatment-naïve (TN) high risk (HR) (CLL):
• epcoritamab + pirtobrutinib
Combination therapy for Ri... Read More
The study is a global, multi-center safety and efficacy trial of epcoritamab, an antibody also known as EPKINLY™ and GEN3013 (DuoBody®-CD3xCD20). Epcoritamab will be tested either in
Relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) as:
* Monotherapy, or
* Combination therapy:
* epcoritamab + venetoclax
* epcoritamab + pirtobrutinib
In Non-United States (US) Participants Only: Treatment-naïve (TN) high risk (HR) (CLL):
• epcoritamab + pirtobrutinib
Combination therapy for Richter's Syndrome (RS):
* epcoritamab + lenalidomide
* epcoritamab + R-CHOP (i.e., rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine \[Oncovin®\] and prednisone).
The study includes participants with R/R or TN HR CLL (non-US participants only)/small lymphocytic lymphoma (SLL) and participants with RS.
The trial consists of two parts, a dose-escalation phase (phase Ib) and an expansion phase (phase II). Participants with RS are only included in the expansion phase.
Epcoritamab will be injected subcutaneously (under the skin). Standard-of-care and combination treatments (venetoclax, pirtobrutinib, lenalidomide, and R-CHOP) will be given either orally (by mouth) or intravenously (in a vein).
Study details include:
* Study duration will be up to 5 years after the last participant's first treatment in the trial.
* The treatment duration for each participant will be between 12 months (1 year) and 24 months (2 years), depending upon the treatment arm assigned.
* The visit frequency will be either weekly, every other week, or monthly, depending upon the part of the study.
All participants will receive active drug; no one will be given placebo. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: O'Neal Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama +86 locations
O'Neal Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama
University of California Davis Medical Center Sacramento, California, California
City of Hope National Medical Center, Duarte, California
Cedars-Sinai Medical Center, Los Angeles, California
David Geffen School of Medicine, Los Angeles, California
Stanford Cancer Center, Palo Alto, California
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida
Memorial Healthcare System, Pembroke Pines, Florida
National Institutes of Health, Bethesda, Maryland
Massachusetts General Hospital, Boston, Massachusetts
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Henry Ford Medical Group, Detroit, Michigan
Hackensack Meridian Hospital, Hackensack, New Jersey
Northwell Health Cancer Institute, Lake Success, New York
Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Duke University Medical Center, Durham, North Carolina
University of Cincinnati, Cincinnati, Ohio
The Ohio State University Comprehensive Cancer Center, Columbus, Ohio
University of Pennsylvania School of medicine, Philadelphia, Pennsylvania
The University of Texas Southwestern Medical Centre, Dallas, Texas
The University of Texas MD Anderson Cancer Center, Houston, Texas
Fred Hutchinson Cancer Research Center, Seattle, Washington
St. George Hospital, Kogarah, New South Wales
Flinders Medical Centre, Bedford Park, South Australia
Barwon Health, Geelong, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria
Alfred Health, Melbourne, Victoria
AZ Sint-Jan, Bruges, Not set
Universitair Ziekenhuis Gent, Gent, Not set
UZ Leuven, Leuven, Not set
Vseobecna Fakultni Nemocnice, Praha, Nové Město
Fakultni nemocnice Hradec Kralove, Hradec Králové, Nový Hradec Králové
Fakultni Nemocnice Ostrava, Ostrava, Poruba
Fakultni nemocnice Brno, Brno, Not set
Fakultni nemocnice Olomouc, Olomouc, Not set
Rigshospitalet, København, Hovedstaden
Aalborg University Hospital, Aalborg, Not set
Odense University Hospital, Odense, Not set
Roskilde Sygehus, Roskilde, Not set
Vejle Sygehus, Vejle, Not set
Århus University Hospital, Århus, Not set
CHU de Montpellier Hôpital Saint Eloi, Montpellier, Cedex 5
CHU Hôpital Haut-Lévêque Bordeaux, Pessac, Gironde
CHU Hôpital de Brabois Nancy, Vandœuvre-lès-Nancy, Meurthe et Moselle
Hôpital Privé du Confluent, Nantes, Pays de la Loire
CHU Clermont Ferrand, Clermont Ferrand cedex, Puy de Dome
Hôpital Saint-Louis, Paris, Not set
Hôpital Universitaire Pitié-Salpêtrière, Paris, Not set
Universitaetsklinikum Ulm, Ulm, Baden Wuerttemberg
Universitaetsklinikum Schleswig-Holstein- Karl-Lennart-Krebscentrum, Kiel, Not set
Universitaetsklinikum Koeln, Koeln, Not set
Bnai Zion Medical Center, Haifa, Not set
Hadassah University Hospital - Ein Kerem, Jerusalem, Not set
Rabin Medical Center-Beilinson Campus, Petah Tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Not set
Istituto di Candiolo, Torino, Candiolo
AOU Arcispedale Sant'Anna, Ferrara, Cona
IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST, Meldola, Forli - Cesena
IRCCS Policlinico Universitario Agostino Gemelli, Roma, Lazio
AOU Policlinico Sant'Orsola Malpighi IRCCS, Bologna, Not set
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, Not set
Ospedale San Raffaele, Milano, Not set
Ospedale Maggiore di Novara, Novara, Not set
AOU Policlinico Umberto I, Roma, Not set
AOU Città della Salute e della Scienza di Torino, Torino, Not set
Maastricht University Medical Center, Maastricht, Limburg
Albert Schweitzer Ziekenhuis, Dordwijk, Dordrecht, South Holland
Amsterdam UMC, Amsterdam, Not set
Universitair Medisch Centrum Groningen, Groningen, Not set
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Pratia Medical Center Katowice (Centrum Medyczne Pratia Katowice), Katowice, Not set
Pratia Malopolskie Medical Center Krakow (Pratia Małopolskie Centrum Medyczne Krakow), Kraków, Not set
Aidport sp z o.o., Skorzewo, Not set
ICO Badalona - Hospital Universitario Germans Trias Pujol, Badalona, Barcelona
AOC Arcispedale Saint'Anna, Coaña, Ferarra
Hospital Clinico Universitario de Valencia, Valencia, València
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Universitario Ramón y Cajal, Madrid, Not set
Hospital Universitario Fundacion Jiménez Díaz, Madrid, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Royal Cornwall Hospital, Truro, Cornwall
Nottingham University Hospitals City Campus, Nottingham, Nottinghamshire
St. James s University Hospital, Leeds, West Yorkshire
Barts Hospital, London, Not set
Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Treatment-naïve High Risk Chronic Lymphocytic Leukemia, Richter's Syndrome
A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma
Recruiting
This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma. Follicular lymphoma is a type of non-Hodgkin lymphoma or NHL. Participants with follicular lymphoma that has come back after treatment (called "relapsed") or did not respond to treatment (called "refractory") are eligible to take part only in Part 1A of the study.
This study is made up of 3 parts: Part 1A (non-randomiz... Read More
This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma. Follicular lymphoma is a type of non-Hodgkin lymphoma or NHL. Participants with follicular lymphoma that has come back after treatment (called "relapsed") or did not respond to treatment (called "refractory") are eligible to take part only in Part 1A of the study.
This study is made up of 3 parts: Part 1A (non-randomized), Part 1B and Part 2 (randomized - controlled).
The aim of Part 1A and Part 1B of the study is to see how safe and tolerable the study drug in combination with chemotherapy is and to determine the dose and schedule of the study drug to be combined with chemotherapy to be used in Part 2 of the study.
The aim of Part 2 of the study is to assess how effective the combination of the study drug with chemotherapy is in comparison with the combination of rituximab and chemotherapy (the current standard-of-care for NHL). Standard-of-care means the usual medication expected and used when receiving treatment for a condition.
The study is looking at several other research questions, including:
* What side effects may happen from taking the study drug
* How much study drug is in the blood at different times
* Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)
* The impact from the study drug on quality-of-life and ability to complete routine daily activities Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2025
Locations: Boca Raton Clinical Research (BRCR) Global, Plantation, Florida +145 locations
Boca Raton Clinical Research (BRCR) Global, Plantation, Florida
Investigative Clinical Research of Indiana, Noblesville, Indiana
University of Kentucky, Lexington, Kentucky
Henry Ford Health System, Detroit, Michigan
Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan
Clinical Research Alliance Inc, Westbury, New York
Center for Oncology and Blood Disorders, Houston, Texas
Community Cancer Trials of Utah, Ogden, Utah
Prohealth Care Inc, Waukesha, Wisconsin
Liverpool Hospital, Liverpool, New South Wales
Calvary Mater Newcastle, Waratah, New South Wales
Pindara Private Hospital, Benowa, Queensland
Karl Landsteiner University Hospital St. Poelten, Saint Poelten, Lower Austria
Medical University of Graz, Graz, Styria
Landeskrankenhaus Hochsteiermark, Leoben, Styria
Kepler University Hospital, Linz, Upper Austria
Innsbruck Medical University, Innsbruck, Not set
Universitatsklinik fur Kinder und Jungendheilkunde, Vienna, Not set
Klinikum Wels-Grieskirchen, Wels, Not set
Verenigde Ziekenhuizen van Waas en Durme, Sint Niklaas, Oost Vlaanderen
Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital, Gent, Oost-Vlaanderen
Algemeen Ziekenhuis St Jan Brugge Oostende Av, Bruges, West Flanders
AZ Groeninge, Kortrijk, West Flanders
Institut Jules Bordet, Brussels, Not set
Centre Hospitalier Regional de la Citadelle, Liege, Not set
Hospital Santa Izabel - Santa Casa de Misericordia da Bahia, Salvador, Bahia
Hospital Sao Rafael, Salvador, Bahia
Ensino e Terapia de Inovacao Clinica Amo (Etica), Salvador, Bahia
Hospital Sirio Libanes Brasilia, Brasilia, Distrito Federal
Instituto DOr de Pesquisa e Ensino Df Star, Brasília, Distrito Federal
Instituto Mario Pena de Ensino Pesquisa e Inovacao, Belo Horizonte, Minas Gerais
Centro Oncologico do Triangulo (COT) - Uberlandia, Uberlandia, Minas Gerais
Hospital Erasto Gaertner, Curitiba, Parana
Liga Norte Riograndense Contra o Cancer, Natal, Rio Grande Do Norte
Instituto Tacchini de Pesquisa em Saude, Bento Goncalves, Rio Grande Do Sul
Instituto do Cancer em Hospital Sao Vicente de Paulo, Passo Fundo, Rio Grande Do Sul
Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul
Centro de Hematologia e Oncologia, Joinville, Santa Catarina
Animi Unidade de Tratamento Oncologico Ltda, Lages, Santa Catarina
Fundacao Pio XII Hospital de Amor, Barretos, Sao Paulo
Amaral Carvalho Hospital, Jau, Sao Paulo
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, Sao Paulo
Instituto Nacional dCancer Jose Alencar Gomes da Silva, Rio de Janeiro, Not set
Instituto Nacional de Cancer Jose Alencar Gomes da Silva, Rio de Janeiro, Not set
Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set
AC Camargo Cancer Center, Sao Paulo, Not set
Clinical Hospital of Medicine School at Sao Paulo University, Sao Paulo, Not set
Casa de Saude Santa Marcelina, Sao Paulo, Not set
Hospital Clinico Universidad de Los Andes, Santiago, Las Condes
Pontificia Universidad Catolica de Chile, Santiago, Region Metropolitana
Centro Oncologia de Precision Universidad Mayor, Santiago, Region Metropolitana
Inmunocel, Santiago, Region Metropolitana
University Hospital Hradec Kralove, Hradec Kralove, North Central Czech Republic
University Hospital Brno, Brno, South Moravian
Cannes Hospital (Centre Hospitalier Cannes Simone Veil), Cannes, Alpes Maritimes
CHRU de Tours, Tours, Centre Val De Loire
Institut de Cancerologie du Gard, Nimes, Gard
Hopital Victor Dupouy Argenteuil, Argenteuil, Ile De France
Centre Hospitalier de Mont-de-Marsan, Mont de Marsan, Nouvelle Aquitaine
Nantes University Hospital, Nantes, Pays De La Loire
The Novo Hospital North West Val Deoise, Cergy Pontoise, Pontoise
Centre Hospitalier Universitaire de Grenoble, Grenoble, Not set
Centre Hospitalier Emile Roux, Le Puy-en-Velay, Not set
Centre Hospitalier de Lens (Centre Hospitalier Dr Schaffner dLens), Lens, Not set
Hopital Saint Louis, Paris, Not set
Centre Hospitalier Universitaire de Bordeaux - Groupe Hospitalier Sud - Hôpital Haut Lévêque, Pessac, Not set
Centre Hospitalier de Saint Nazaire, Saint Nazaire, Not set
CHU de Saint-Etienne, Saint-Etienne, Not set
Stadtisches Krankenhaus Kiel, Kiel, Not set
MVZ fuer Haematologie und Onkologie Rhein-Kreis GmbH, Neuss, Not set
Shaare Zedek Medical Center, Jerusalem, Yerushalayim
Soroka University Medical Center, Be'er Sheva, Not set
Rambam Health Care Campus, Haifa, Not set
Hadassah Medical Center, Jerusalem, Not set
Rabin Medical Center, Petah Tikva, Not set
The Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Assuta Medical Centers, Tel Aviv, Not set
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Forli Cesena
Azienda Ospedaliera Ordine Mauriziano Torino, Presidio Umberto I of Turin, Torino, Piemonte
Azienda Ospedaliera Universitario Policlinico Palermo, Palermo, Sicily
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Not set
Istituto Europeo di Oncologia, Milano, Not set
ASST Grande Ospedale Metropolitano Niguarda - Main Address, Milan, Not set
A.O.U. di Modena, Modena, Not set
Federico II University, Napoli, Not set
Azienda Ospedaliera di Perugia, Perugia, Not set
University of Pisa, Section of Hematology, Pisa, Not set
Azienda Ospedaliera Regionale San Carlo, Potenza, Not set
UO Ematologia Ravenna, Ravenna, Not set
Azienda Unita Sanitaria Locale Irccs Arcispedale Santa Maria Nuova, Reggio Emilia, Not set
Azienda Osperdaliero-Universitaria Policlinico Umberto 1, Rome, Not set
Azienda Sanitaria Universitaria del Friuli Centrale, Udine, Not set
Matopolskie Centrum Medyczne S.C., Krakow, Malopolskie
Aidport, Skorzewo, Wielkopolska
Szpital Uniwersytecki Nr2 Bydgoszcz, Bydgoszcz, Not set
Uniwersyteckie Centrum Kliniczne, Building of the Non-Invasive Medicine Center, Gdansk, Not set
Pratia Onkologia Katowice, Katowice, Not set
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. Mikolaja Kopernika w Lodzi (Copernicus Memorial Hospital), Lodz, Not set
Centrum Innowacyjnych Terapii Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set
Szpital Szpecjalistyczny w Walbrzychu, Walbrzych, Not set
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warszawa, Warszawa, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Andalusia
Hospital Universitario Central de Asturias, Oviedo, Asturias
Parc Tauli Sabadell Hospital Universitari, Sabadell, Barcelona
Hospital Universitari Mutua Terrassa, Terrassa, Barcelona
Cruces University Hospital (Hospital Universitario Cruces), Barakaldo, Bizkaia
Hospital General Universitario Doctor Balmis Alicante, Alicante, Comunidad Valenciana
Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, Madrid
Hospital Universitario Quiron Salud Madrid, Pozuelo de Alarcon, Madrid
Hospital Universitario de Navarra, Pamplona, Navarra
Hospital Universitario Lucus Augusti, Lugo, Not set
Clinica Universidad de Navarra - Madrid, Madrid, Not set
Hospital Universitario Infanta Leonor, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Complexo Hospitalario Universitario de Ourense, Ourense, Not set
Clinica Universidad de Navarra- Pamplona, Pamplona, Not set
Hospital Universitario de Salamanca, Salamanca, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital General Universitario de Toledo, Toledo, Not set
Instituto Valenciano de Oncologia, Valencia, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
Chang Gung Memorial Hospital Kaohsiung, Kaohsiung City, Not set
Kaohsiung Medical University Hospital, Kaohsiung, Not set
Taipei Medical University - Shuang Ho Hospital, New Taipei City, Not set
Taipei Veterans General Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Taipei Medical University Multipal Wan Fang University, Taipei, Not set
Chulalongkorn University, Bangkok, Krung Thep Maha Nakhon [Bangko]
Khon Kaen University, Khon Kaen, Not set
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Yenimahalle, Ankara
Gazi University, Ankara, Central Anatolia
VM Medical Park Mersin Hospital, Mezitli, Mersin
Sakarya University, Sakarya, Serdivan
Tekirdag Namik Kemal University Hospital, Tekirdag, Suleymanpasa
Liv Hospital Ankara, Ankara, Not set
VKV American Hopital, Istanbul, Not set
Istanbul University, Istanbul, Not set
Erci̇yes Uni̇versi̇ty, Kayseri, Not set
Ondokuz Mayıs University, Samsun, Not set
Zonguldak Bulent Ecevit University, Zonguldak, Not set
Royal Cornwall Hospital, Truro, Cornwall
The Hillingdon Hospitals NHS Foundation Trust, Uxbridge, London
University Hospitals Birmingham NHS Foundation Trust, Birmingham, West Midlands
NHS Grampian: Aberdeen Royal Infirmary, Aberdeen, Not set
Conditions: Follicular Lymphoma (FL)
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
Active Not Recruiting
The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.
The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma. Read Less
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/22/2025
Locations: UCSF Medical Center at Mission Bay, San Francisco, California +16 locations
UCSF Medical Center at Mission Bay, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
University of Chicago - Comer Children's Hospital, Chicago, Illinois
Dana-Farber Cancer Institute, Boston, Massachusetts
Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Texas Childrens Hospital, Houston, Texas
Perth Children's Hospital, Perth, Western Australia
UZ Gent, Gent, Oost-Vlaanderen
Centre Leon Berard, Lyon, Rhône-Alpes
Institut Curie, Paris CEDEX 05, Not set
Universitätsklinikum Köln, Köln, Not set
Istituto Nazionale dei Tumori, Milano, Lombardie
National Cancer Center Hospital, Chuo-ku, Tokyo
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]
Hospital Infantil Universitario Niño Jesús, Madrid, Not set
Alder Hey Children's Hospital, Liverpool, Not set
Conditions: Neuroblastoma
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor
Active Not Recruiting
This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol (NCT05999994) which is a platform to accelerate the development of new treatments for pediatric and young adult participants with cancer. Your participation in this trial could last 12 months or longer, d... Read More
This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol (NCT05999994) which is a platform to accelerate the development of new treatments for pediatric and young adult participants with cancer. Your participation in this trial could last 12 months or longer, depending on how you and your tumor respond. Read Less
Gender:
ALL
Ages:
Between 12 months and 29 years
Trial Updated:
07/18/2025
Locations: Phoenix Children's Hospital, Phoenix, Arizona +21 locations
Phoenix Children's Hospital, Phoenix, Arizona
Children's Hospital of Los Angeles, Los Angeles, California
Children's National Medical Center, Washington, District of Columbia
Washington University, Saint Louis, Missouri
Memorial Sloan Kettering Cancer Center, New York, New York
Children's Hospital of Philadelphia (CHOP), Philadelphia, Pennsylvania
Royal Children's Hospital, Parkville, Victoria
Universitaetsklinikum Freiburg, Freiburg, Baden-Württemberg
Universitaetsklinikum Essen, Essen, Nordrhein-Westfalen
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Lombardia
Humanitas, Rozzano, Milano
Ospedale Pediatrico Bambino Gesù, Rome, Roma
Azienda Ospedaliera di Padova, Padova, Veneto
National Cancer Center Hospital, Chuo-ku, Tokyo
Kyushu University Hospital, Fukuoka, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
University College London Hospital, London, London, City Of
Royal Marsden Hospital (Sutton), London, Sutton
Royal Manchester Children's Hospital, Manchester, Not set
The Christie, Manchester, Not set
Conditions: Desmoplastic Small Round Cell Tumor
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma
Recruiting
This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin lymphoma or NHL).
This study will be made up of two parts: Part 1 (non-randomized) and Part 2 (randomized - controlled).
The aim of Part 1 of the study is to see how safe and tolerable the study drug is when given alone.
The aim of Part 2 of the study is to see how the study drug works compared... Read More
This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin lymphoma or NHL).
This study will be made up of two parts: Part 1 (non-randomized) and Part 2 (randomized - controlled).
The aim of Part 1 of the study is to see how safe and tolerable the study drug is when given alone.
The aim of Part 2 of the study is to see how the study drug works compared to rituximab (called the "comparator drug") and chemotherapy (the current standard of care for NHL). Standard of care means the usual medication expected and used when receiving treatment for a condition.
The study is looking at several other research questions, including:
* What side effects may happen from taking the study drug
* How much study drug is in the blood at different times
* Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)
* How the study drug affects quality of life and ability to complete routine daily activities. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: University of Arizona Cancer Center, Tucson, Arizona +186 locations
University of Arizona Cancer Center, Tucson, Arizona
David Geffen School of Medicine at UCLA, Los Angeles, California
UC Irvine Health, Orange, California
Investigative Clinical Research of Indiana, Noblesville, Indiana
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Karmanos Cancer Institute, Detroit, Michigan
Hattiesburg Clinic, Hattiesburg, Mississippi
Icahn School of Medicine at Mt Sinai, New York, New York
Stony Brook University Hospital, Stony Brook, New York
Clinical Research Alliance Inc, Westbury, New York
University of North Carolina, Chapel Hill, North Carolina
Levine Cancer Institute, Charlotte, North Carolina
University Hospitals Cleveland Medical Center, Cleveland, Ohio
Vanderbilt University Medical Center, Nashville, Tennessee
Center for Oncology and Blood Disorders, Houston, Texas
HOPE Cancer Center of East Texas, Tyler, Texas
Huntsman Cancer Institute - Oncology Division, Salt Lake City, Utah
University of Virginia, Charlottesville, Virginia
Virginia Commonwealth University, Richmond, Virginia
Prohealth Care Inc, Waukesha, Wisconsin
Ingham Institute, Liverpool, New South Wales
Icon Cancer Centre - Wesley, Auchenflower, Queensland
Flinders Medical Centre, Bedford Park, South Australia
Monash Health, Clayton, Victoria
Epworth Freemasons, East Melbourne, Victoria
St Vincent's Hospital - Melbourne, Fitzroy, Victoria
Alfred Hospital and Monash University, Melbourne, Victoria
Ordensklinikum Linz, Linz, Osterreich
Ordensklinikum Linz Gmbh, Elisabethinen, Linz, Not set
Uniklinikum Salzburg (LKH) Universitatsklinik fur Innere Medizin III, Salzburg, Not set
Medical University of Vienna, Vienna, Not set
Hanusch Krankenhaus, Vienna, Not set
AZ St.-Elisabeth Herentals vzw, Herentals, Antwerp
Hopital De Jolimont, Haine-Saint-Paul, Hainaut
Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital, Gent, Oost-Vlaanderen
Ziekenhuis Netwerk Antwerpen Stuivenberg, Antwerp, Not set
Institut Jules Bordet, Brussels, Not set
Ensino e Terapia de Inovacao Clinica Amo (Etica), Salvador, Bahia
Instituto Mario Pena de Ensino Pesquisa e Inovacao, Belo Horizonte, Minas Gerais
Liga Norte Riograndense Contra o Cancer, Natal, Rio Grande Do Norte
Instituto do Cancer em Hospital Sao Vicente de Paulo, Passo Fundo, Rio Grande Do Sul
Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul
Centro de Hematologia e Oncologia, Joinville, Santa Catarina
Animi Unidade de Tratamento Oncologico Ltda, Lages, Santa Catarina
Fundacao Pio XII Hospital de Amor, Barretos, Sao Paulo
Amaral Carvalho Hospital, Jau, Sao Paulo
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo, Ribeirao Preto, Sao Paulo
Instituto DOr de Pesquisa e Ensino Df Star, Brasilia, Not set
Instituto Nacional de Cancer Jose Alencar Gomes da Silva, Rio de Janeiro, Not set
Instituto Americas, Rio de Janeiro, Not set
Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set
AC Camargo Cancer Center, Sao Paulo, Not set
Clinical Hospital of Medicine School at Sao Paulo University, Sao Paulo, Not set
Casa de Saude Santa Marcelina, Sao Paulo, Not set
Tom Baker Cancer Center, Calgary, Alberta
Saint John Regional Hospital, Saint John, New Brunswick
Cisss de la Monteregie-Centre, Greenfield Park, Quebec
CHU de Quebec - Universite Laval, Quebec City, Quebec
Ciusss de Lestrie - Centre Hospitalier Universitaire de Sherbrooke (CHUS), Sherbrooke, Quebec
Fundacion Arturo Lopez Perez, Santiago, Region Metropolitana
Inmunocel, Santiago, Region Metropolitana
Clinica Alemana de Santiago, Santiago, Region Metropolitana
Centro Oncologia de Precision Universidad Mayor, Santiago, Not set
University Hospital Hradec Kralove, Hradec Kralove, Not set
University Hospital Kralovske Vinohrady, Prague, Not set
Vseobecna Fakultni Nemocnice, Praha, Not set
Centre Hospitalier Universitaire (CHU) Rennes, Rennes, Bretagne
Centre Hospitalier Regional Universitaire de Tours, Tours, Centre Val De Loire
Hopital Victor Dupouy Argenteuil, Argenteuil, Ile De France
Gustave Roussy, Villejuif, Ile De France
Nantes University Hospital, Nantes, Pays De La Loire
Hopital de la Conception, Marseille, Provence-Alpes-Cote d'Azur
Centre Hospitalier Universitaire Angers, Angers, Not set
Institut Paoli Calmettes, Marseille, Not set
Hopital Saint Louis, Paris, Not set
Hopital Saint-Antoine, Paris, Not set
Centre Hospitalier Universitaire (CHU) de Poitiers, Poitiers, Not set
Institut de Cancerologie Strasbourg Europe (ICANS), Strasbourg, Not set
University Hospital Wurzburg, Würzburg, Bavaria
Kliniken Ostalb Stauferklinikum Schwab Gmund, Mutlangen, Gmund
Clinic Frankfurt (Oder), Frankfurt, Hesse
Universitatsmedizin der Johannes-Gutenberg Universitat Mainz, Mainz, Rheinland-Pfalz
Hematological Praxis Dresden, Dresden, Sachsen
Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set
University Hospital Carl Gustav Carus, Dresden, Not set
Stadtisches Krankenhaus Kiel, Kiel, Not set
Samson Assuta Ashdod University Hospital, Ashdod, Not set
Bnai Zion Medical Center, Haifa, Not set
Hadassah Medical Center, Jerusalem, Not set
Galilee Medical Center, Nahariya, Not set
Rabin Medical Center, Petah-Tikva, Not set
Chaim Sheba Medical Center, Ramat-Gan, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Istituto Romagnolo Per Lo Studio Dei Tumori, Meldola, Forli Cesena
Irccs Aou Di Bologna- Policlinico Di Sant'Orsola Malpighi, Bologna, Italia
Pia Fondazione Panico, Tricase, Lecce
IRCCS Ospedale Policlinico San Martino, Genoa, Liguria
Candiolo Cancer Institute, FPO, IRCCS, Candiolo, Torino
UOC Ematologia e Terapia Cellulare - PO Mazzoni AST Ascoli Piceno, Ascoli Piceno, Not set
Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set
Istituto Europeo di Oncologia, Milano, Not set
Federico II University, Napoli, Not set
AOU Maggiore della Carita-SCDU Ematologia, Novara, Not set
UO Ematologia Ravenna, Ravenna, Not set
Santa Maria della Misericordia, Udine, Not set
Ospedale dell'Angelo - Varese, Varese, Not set
Center for Hematologic Malignancy, Goyang, Gyeonggi-do
St. Vincents Hospital - The Catholic University of Korea, Suwon-si, Gyeonggi-do
Ajou University Hospital, Suwon-si, Gyeonggi-do
Dong-A University Hospital, Busan, Not set
Pusan National University Hospital, Busan, Not set
Jeonbuk National University Hospital, Jeonju, Not set
Seoul St. Mary's Hospital, Seoul, Not set
Uniwersytecki Szpital Kliniczny, Wroclaw, Dolnoslaskie
Specjalistyczny Szpital im A. Sokolowskiego w Walbrzychu, Walbrzych, Lower Silesian
Pratia MCM Krakow, Krakow, Malopolska
Uniwersyteckie Centrum Kliniczne, Gdansk, Pomorskie
Cm Pratia Poznan, Skorzewo Poznan, Wielkopolska
Aidport, Skorzewo, Wielkopolska
Pratia Onkologia Katowice, Katowice, Not set
Copernicus Memorial Hospital, Lodz, Not set
Centrum Innowacyjnych Terapii Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warszawa, Warszawa, Not set
University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruna
Hospital Universitario Virgen De La Victoria Malaga, Malaga, Andalucia
Hospital Universitario Virgen Macarena, Sevilla, Andalucia
Hospital Universitario Central De Asturias, Oviedo, Asturias
Son Espases University Hospital, Palma, Balearic Islands
Cruces University Hospital (Hospital Universitario Cruces), Barakaldo, Bizkaia
Hospital Universitario Marques de Valdecilla, Santander, Cantabria
Complejo Hospitalario Universitario de a Coruna, A Coruna, Galicia
Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Madrid
Hospital Clinico Universitario Virgen De La Arrixaca, El Palmar, Murcia
Hospital Universitario de Navarra, Pamplona, Navarra
University Hospital Vall d'Hebron, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Virgen De Las Nieves De Granada, Granada, Not set
Gregorio Maranon, Madrid, Not set
Clinica Universidad de Navarra, Madrid, Not set
Fundacion Jimenez Diaz University Hospital, Madrid, Not set
University Hospital & Research Institute, Madrid, Not set
Hospital Universitario HM Sanchinarro, Servicio de Hematologia, Madrid, Not set
Morales Meseguer Hospital, Murcia, Not set
Complexo Hospitalario Universitario de Ourense, Ourense, Not set
Hospital Universitario de Salamanca, Salamanca, Not set
Hospital Universitario Virgen de Valme, Sevilla, Not set
University Hospital Virgen del Rocio, Seville, Not set
Hospital General Universitario de Toledo, Toledo, Not set
Hospital Clinico Universitario Valencia, Valencia, Not set
Hospital Universitari and Politecnic La Fe, Valencia, Not set
Hospital Clinico Lozano Blesa, Zaragoza, Not set
Kantonsspital Baden, Baden, Aargau
Cantonal Hospital St Gallen, St Gallen, Saint Gallen
Kantonsspital Winterthur Medical Oncology, Winterthur, Schweiz
University Hospital Basel, Basel, Not set
Inselspital Bern University Hospital, Bern, Not set
Chang Gung Medical Foundation Chia Yi Branch, Puzi City, Chiayi County
Chang Gung Memorial Hospital Linkou, Taoyuan City, Guishan District
Changhua Christian Hospital, Changhua City, Not set
Chung-Ho Memorial Hospital, Kaohsiung, Not set
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set
Taipei Medical University-Shuang Ho Hospital, New Taipei City, Not set
Taichung General Veterans Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
Tri-Service General Hospital, Taipei City, Not set
National Taiwan University Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Taipei Municipal Wan Fang Hospital, Taipei, Not set
Ankara University Faculty of Medicine, Mamak, Ankara
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Yenimahalle, Ankara
Gazi University, Ankara, Central Anatolia
VM Medical Park Mersin Hospital, Mezitli, Mersin
Tekirdag Namik Kemal University Hospital, Tekirdag, Suleymanpasa
Liv Hospital Ankara, Ankara, Not set
VKV American Hopital, Istanbul, Not set
Istanbul University Istanbul Faculty of Medicine, Istanbul, Not set
Ege University, Izmir, Not set
Erci̇yes Uni̇versi̇ty, Kayseri, Not set
Sakarya University Medical Faculty, Sakarya, Not set
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi, Samsun, Not set
Zonguldak Bulent Ecevit University, Zonguldak, Not set
Royal Cornwall Hospital NHS Trust, Truro, Cornwall
Derriford Hospital and the Royal Eye Infirmary, Plymouth, Devon
University Hospitals Dorset, Bournemouth, Dorset
Beatson West of Scotland Cancer Centre, Glasgow, Lanarkshire
Norfolk and Norwich University Hospital, Norwich, Norfolk
Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, Not set
Conditions: Follicular Lymphoma (FL)
A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
Recruiting
This is a Phase III, 2-arm, randomised, open-label, multicentre, global study assessing the efficacy and safety of neoadjuvant Dato-DXd plus durvalumab followed by adjuvant durvalumab with or without chemotherapy compared with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab with or without chemotherapy in participants with previously untreated TNBC or hormone receptor-low/HER2-negative breast cancer.
This is a Phase III, 2-arm, randomised, open-label, multicentre, global study assessing the efficacy and safety of neoadjuvant Dato-DXd plus durvalumab followed by adjuvant durvalumab with or without chemotherapy compared with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab with or without chemotherapy in participants with previously untreated TNBC or hormone receptor-low/HER2-negative breast cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Research Site, Daphne, Alabama +355 locations
Research Site, Daphne, Alabama
Research Site, Goodyear, Arizona
Research Site, Phoenix, Arizona
Research Site, Tucson, Arizona
Research Site, Jonesboro, Arkansas
Research Site, Rogers, Arkansas
Research Site, Bakersfield, California
Research Site, Fullerton, California
Research Site, Irvine, California
Research Site, Los Angeles, California
Research Site, Los Angeles, California
Research Site, Newport Beach, California
Research Site, Orange, California
Research Site, Santa Barbara, California
Research Site, Santa Rosa, California
Research Site, Sylmar, California
Research Site, Torrance, California
Research Site, Van Nuys, California
Research Site, Aurora, Colorado
Research Site, Fort Collins, Colorado
Research Site, Longmont, Colorado
Research Site, Bridgeport, Connecticut
Research Site, New Haven, Connecticut
Research Site, Newark, Delaware
Research Site, Fort Myers, Florida
Research Site, Jacksonville, Florida
Research Site, Jacksonville, Florida
Research Site, Port Saint Lucie, Florida
Research Site, Saint Petersburg, Florida
Research Site, Tallahassee, Florida
Research Site, West Palm Beach, Florida
Research Site, Atlanta, Georgia
Research Site, Atlanta, Georgia
Research Site, Chicago Ridge, Illinois
Research Site, Dyer, Indiana
Research Site, Des Moines, Iowa
Research Site, Edgewood, Kentucky
Research Site, Louisville, Kentucky
Research Site, Baton Rouge, Louisiana
Research Site, Annapolis, Maryland
Research Site, Boston, Massachusetts
Research Site, Detroit, Michigan
Research Site, Grand Rapids, Michigan
Research Site, Traverse City, Michigan
Research Site, Burnsville, Minnesota
Research Site, Minneapolis, Minnesota
Research Site, Columbia, Missouri
Research Site, Saint Louis, Missouri
Research Site, Omaha, Nebraska
Research Site, Henderson, Nevada
Research Site, Camden, New Jersey
Research Site, East Brunswick, New Jersey
Research Site, New Brunswick, New Jersey
Research Site, Santa Fe, New Mexico
Research Site, Commack, New York
Research Site, New York, New York
Research Site, Charlotte, North Carolina
Research Site, Durham, North Carolina
Research Site, Winston-Salem, North Carolina
Research Site, Blue Ash, Ohio
Research Site, Canton, Ohio
Research Site, Eugene, Oregon
Research Site, Portland, Oregon
Research Site, Horsham, Pennsylvania
Research Site, Philadelphia, Pennsylvania
Research Site, Pittsburgh, Pennsylvania
Research Site, Providence, Rhode Island
Research Site, Chattanooga, Tennessee
Research Site, Nashville, Tennessee
Research Site, Nashville, Tennessee
Research Site, Austin, Texas
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, Dallas, Texas
Research Site, El Paso, Texas
Research Site, Flower Mound, Texas
Research Site, Fort Worth, Texas
Research Site, Houston, Texas
Research Site, Irving, Texas
Research Site, San Antonio, Texas
Research Site, Webster, Texas
Research Site, Fairfax, Virginia
Research Site, Norfolk, Virginia
Research Site, Richmond, Virginia
Research Site, Roanoke, Virginia
Research Site, Winchester, Virginia
Research Site, Tacoma, Washington
Research Site, Madison, Wisconsin
Research Site, Darlinghurst, Not set
Research Site, East Melbourne, Not set
Research Site, Heidelberg, Not set
Research Site, Herston, Not set
Research Site, Nedlands, Not set
Research Site, Waratah, Not set
Research Site, Feldkirch, Not set
Research Site, Graz, Not set
Research Site, Innsbruck, Not set
Research Site, Linz, Not set
Research Site, Salzburg, Not set
Research Site, Antwerpen, Not set
Research Site, Brasschaat, Not set
Research Site, Charleroi, Not set
Research Site, Gent, Not set
Research Site, Leuven, Not set
Research Site, Libramont-Chevigny, Not set
Research Site, Brasilia, Not set
Research Site, Curitiba, Not set
Research Site, Fortaleza, Not set
Research Site, Londrina, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Ribeirão Preto, Not set
Research Site, Santo Andre, Not set
Research Site, São Paulo, Not set
Research Site, Taubaté, Not set
Research Site, Vitória, Not set
Research Site, Plovdiv, Not set
Research Site, Shumen, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Vratza, Not set
Research Site, Calgary, Alberta
Research Site, Abbotsford, British Columbia
Research Site, Vancouver, British Columbia
Research Site, St. John's, Newfoundland and Labrador
Research Site, Barrie, Ontario
Research Site, London, Ontario
Research Site, Oshawa, Ontario
Research Site, Toronto, Ontario
Research Site, Levis, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Sherbrooke, Quebec
Research Site, St-Jerome, Quebec
Research Site, Saskatoon, Saskatchewan
Research Site, Montreal, Not set
Research Site, Ottawa, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Bengbu, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Jinan, Not set
Research Site, Kunming, Not set
Research Site, Linhai, Not set
Research Site, Nanchang, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Nanjing, Not set
Research Site, Nanning, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Shenyang, Not set
Research Site, Shijiazhuang, Not set
Research Site, Suining, Not set
Research Site, Suzhou, Not set
Research Site, Tianjin, Not set
Research Site, Urumqi, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Xintai, Not set
Research Site, Zhaoqing, Not set
Research Site, Zhengzhou, Not set
Research Site, Avignon, Not set
Research Site, Bayonne, Not set
Research Site, Caen Cedex 5, Not set
Research Site, Clermont Ferrand, Not set
Research Site, Limoges, Not set
Research Site, Lyon, Not set
Research Site, Marseille, Not set
Research Site, Montpellier, Not set
Research Site, Nice, Not set
Research Site, Paris, Not set
Research Site, Reims Cedex, Not set
Research Site, Saint Herblain, Not set
Research Site, Toulouse, Not set
Research Site, Vandoeuvre les Nancy, Not set
Research Site, Villejuif Cedex, Not set
Research Site, Augsburg, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Dessau-Roßlau, Not set
Research Site, Dresden, Not set
Research Site, Erlangen, Not set
Research Site, Essen, Not set
Research Site, Esslingen am Neckar, Not set
Research Site, Frankfurt am Main, Not set
Research Site, Freiburg, Not set
Research Site, Freiburg, Not set
Research Site, Hamburg, Not set
Research Site, Hannover, Not set
Research Site, Hannover, Not set
Research Site, Heidelberg, Not set
Research Site, Kiel, Not set
Research Site, Mainz, Not set
Research Site, Mannheim, Not set
Research Site, München, Not set
Research Site, München, Not set
Research Site, Münster, Not set
Research Site, Trier, Not set
Research Site, Ulm, Not set
Research Site, Hong Kong, Not set
Research Site, Hong Kong, Not set
Research Site, Kwai Chung, Not set
Research Site, Budapest, Not set
Research Site, Kecskemét, Not set
Research Site, Miskolc, Not set
Research Site, Nyíregyháza, Not set
Research Site, Salgótarján, Not set
Research Site, Szekszárd, Not set
Research Site, Bengaluru, Not set
Research Site, Dehradun, Not set
Research Site, Delhi, Not set
Research Site, Delhi, Not set
Research Site, Kolkata, Not set
Research Site, Kolkata, Not set
Research Site, Marg Jaipur, Not set
Research Site, Nagpur, Not set
Research Site, Nashik, Not set
Research Site, Puducherry, Not set
Research Site, Thiruvananthapuram, Not set
Research Site, Vadodara, Not set
Research Site, Empoli, Not set
Research Site, Lucca, Not set
Research Site, Macerata, Not set
Research Site, Milano, Not set
Research Site, Modena, Not set
Research Site, Napoli, Not set
Research Site, Padova, Not set
Research Site, Roma, Not set
Research Site, Rozzano, Not set
Research Site, Torino, Not set
Research Site, Tricase, Not set
Research Site, Udine, Not set
Research Site, Akashi-shi, Not set
Research Site, Akita-shi, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Chiba-shi, Not set
Research Site, Chuo-ku, Not set
Research Site, Chuo-ku, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Fukushima-shi, Not set
Research Site, Gifu-shi, Not set
Research Site, Hidaka-shi, Not set
Research Site, Hirakata-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Hiroshima-shi, Not set
Research Site, Isehara-shi, Not set
Research Site, Kashiwa, Not set
Research Site, Koto-ku, Not set
Research Site, Kumamoto-shi, Not set
Research Site, Kurume-shi, Not set
Research Site, Kyoto-shi, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Okayama, Not set
Research Site, Osaka-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Shinagawa-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Sunto-gun, Not set
Research Site, Tsu-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Daegu, Not set
Research Site, Goyang-si, Not set
Research Site, Seongnam, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, George Town, Not set
Research Site, Kuala Lumpur, Not set
Research Site, Kuala Lumpur, Not set
Research Site, Kuching, Not set
Research Site, Selangor, Not set
Research Site, Bialystok, Not set
Research Site, Bydgoszcz, Not set
Research Site, Gdańsk, Not set
Research Site, Gdynia, Not set
Research Site, Kraków, Not set
Research Site, Tomaszów Mazowiecki, Not set
Research Site, Warszawa, Not set
Research Site, Wroclaw, Not set
Research Site, Łódź, Not set
Research Site, Singapore, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Granada, Not set
Research Site, Hospitalet deLlobregat, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Santiago de Compostela, Not set
Research Site, Sevilla, Not set
Research Site, Zaragoza, Not set
Research Site, Baden, Not set
Research Site, Basel, Not set
Research Site, Bern, Not set
Research Site, Frauenfeld, Not set
Research Site, Genolier, Not set
Research Site, Rennaz, Not set
Research Site, Changhua, Not set
Research Site, Kaohsiung, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Dusit, Not set
Research Site, Muang, Not set
Research Site, Songkhla, Not set
Research Site, Adapazari, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Istanbul, Not set
Research Site, Kayseri, Not set
Research Site, Samsun, Not set
Research Site, Birmingham, Not set
Research Site, Cardiff, Not set
Research Site, Edinburgh, Not set
Research Site, Guildford, Not set
Research Site, Lancaster, Not set
Research Site, London, Not set
Research Site, Northampton, Not set
Research Site, Oxford, Not set
Research Site, Taunton, Not set
Research Site, Hanoi, Not set
Research Site, Ho Chi Minh city, Not set
Research Site, Vinh, Not set
Conditions: Breast Cancer
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
Active Not Recruiting
The purpose of this study is to compare the efficacy of Bortezomib, Lenalidomide and Dexamethasone (VRd) induction followed by a single administration of ciltacabtagene autoleucel (cilta-cel) versus VRd induction followed by Lenalidomide and Dexamethasone (Rd) maintenance in newly diagnosed multiple myeloma participants for whom ASCT is not planned as initial therapy in terms of Progression Free Survival (PFS).
The purpose of this study is to compare the efficacy of Bortezomib, Lenalidomide and Dexamethasone (VRd) induction followed by a single administration of ciltacabtagene autoleucel (cilta-cel) versus VRd induction followed by Lenalidomide and Dexamethasone (Rd) maintenance in newly diagnosed multiple myeloma participants for whom ASCT is not planned as initial therapy in terms of Progression Free Survival (PFS). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: UCSF, San Francisco, California +135 locations
UCSF, San Francisco, California
Yale Cancer Center, New Haven, Connecticut
University of Miami Health System, Miami, Florida
AdventHealth Cancer Institute, Orlando, Florida
University of Iowa Hospitals and Clinics, Iowa City, Iowa
University of Kentucky, Lexington, Kentucky
Norton Cancer Institute, Louisville, Kentucky
University Of Maryland Medical Center, Baltimore, Maryland
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Cancer Institute, Detroit, Michigan
Columbia University Medical Center, New York, New York
Memorial Sloan-Kettering Cancer Center, New York, New York
New York Presbyterian-Weill Cornell Medical College, New York, New York
Levine Cancer Institute, Charlotte, North Carolina
Thomas Jefferson University, Philadelphia, Pennsylvania
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
University of Virginia, Charlottesville, Virginia
Medical College Of Wisconsin, Milwaukee, Wisconsin
Hospital Aleman, Buenos Aires, Not set
Hospital Italiano de Buenos Aires, Buenos Aires, Not set
Hospital Privado Universitario De Cordoba, Cordoba, Not set
Royal Prince Alfred Hospital, Camperdown, Not set
St Vincents Hospital Melbourne, Fitzroy, Not set
Austin Health, Heidelberg, Not set
Royal Brisbane and Womens Hospital, Herston, Not set
Alfred Health, Melbourne, Not set
Peter MacCallum Cancer Centre, Melbourne, Not set
Fiona Stanley Hospital, Murdoch, Not set
Calvary Mater Newcastle Hospital, Waratah, Not set
Western Sydney Local Health District, Westmead, Not set
Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie, Graz, Not set
Krankenhaus der Elisabethinen Linz, Linz, Not set
LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Not set
Medical University of Vienna Universitatsklinik fur Innere Medizin I, Vienna, Not set
Universitair Ziekenhuis - Antwerpen, Antwerp, Not set
AZ St.-Jan Brugge-Oostende AV, Brugge, Not set
UZ Gent, Gent, Not set
UZ Leuven, Leuven, Not set
Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman, Liege, Not set
Hospital Sao Rafael, Salvador, Not set
Fundacao Antonio Prudente A C Camargo Cancer Center, Sao Paulo, Not set
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Sao Paulo, Not set
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta
Vancouver General Hospital, Vancouver, British Columbia
Juravinski Cancer Centre, Hamilton, Ontario
Princess Margaret Cancer Centre University Health Network, Toronto, Ontario
Hopital Maisonneuve Rosemont, Montreal, Quebec
Fakultni nemocnice Brno, Brno, Not set
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set
Fakultni Nemocnice Ostrava, Ostrava - Poruba, Not set
Vseobecna fakultni nemocnice v Praze, Praha 2, Not set
Aarhus University Hospital, Aarhus C, Not set
Rigshospitalet, Copenhagen, Not set
Odense Universitetshospital, Odense C, Not set
Helsinki University Hospital, Helsinki, Not set
Oulu University Hospital, Oulu, Not set
Turku University Hospital, Turku, Not set
Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez, Lille Cedex, Not set
C.H.U. Hotel Dieu - France, Nantes, Not set
Hopital Saint Louis, Paris cedex 10, Not set
CHU Poitiers - Hopital la Miletrie, Poitiers, Not set
Institut Universitaire du cancer de Toulouse-Oncopole, Toulouse cedex 9, Not set
Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Not set
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Not set
Universitatsklinikum Freiburg, Freiburg, Not set
Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Not set
Universitaetsklinikum Leipzig, Leipzig, Not set
Universitatsmedizin der Johannes Gutenberg Universitat Mainz, Mainz, Not set
Klinikum Großhadern der Ludwig-Maximilians-Universität, München, Not set
Universitaetsklinikum Regensburg, Regensburg, Not set
Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany, Tubingen, Not set
Universitatsklinikum Wurzburg, Wuerzburg, Not set
Alexandra General Hospital of Athens, Athens, Not set
Attikon University General Hospital of Attica, Athens, Not set
G.Papanikolaou, Thessaloniki, Not set
Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely, Budapest, Not set
Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set
St James Hospital, Dublin, Not set
Hadassah University Hospita Ein Kerem, Jerusalem, Not set
Sheba Medical Center Tel Hashomer, Ramat Gan, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Juntendo University Hospital, Bunkyo Ku, Not set
Kyushu University Hospital, Fukuoka, Not set
Hyogo Medical University Hospital, Hyôgo, Not set
Kanazawa University Hospital, Kanazawa, Not set
University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set
Nagoya City University Hospital, Nagoya, Not set
Okayama University Hospital, Okayama, Not set
Hokkaido University Hospital, Sapporo, Not set
Tohoku University Hospital, Sendai, Not set
Japanese Red Cross Medical Center, Shibuya, Not set
Chonnam National University Hwasun Hospital, Jeollanam-do, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set
VU Medisch Centrum, Amsterdam, Not set
University Medical Center Groningen, Groningen, Not set
UMC Radboud, Nijmegen, Not set
Erasmus MC, Rotterdam, Not set
Oslo universitetssykehus HF, Rikshospitalet, Oslo, Not set
Uniwersyteckie Centrum Kliniczne, Gdansk, Not set
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz w Gliwicach, Gliwice, Not set
Centrum Onkologii Ziemi Lubelskiej im sw Jana z Dukli, Lublin, Not set
Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set
Instytut Hematologii i Transfuzjologii, Warszawa, Not set
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu, Wroclaw, Not set
Instituto Portugues de Oncologia, Lisboa, Not set
Instituto Portugues de Oncologia, Porto, Not set
Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set
Hosp Univ Vall D Hebron, Barcelona, Not set
Instituto Catalan Deoncologia Hospital Duran I Reynals, L'Hospitalet de Llobregat, Not set
Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set
Hosp. Univ. 12 de Octubre, Madrid, Not set
Hosp. Univ. Virgen de La Arrixaca, Murcia, Not set
Clinica Univ. de Navarra, Pamplona, Not set
Hosp Clinico Univ de Salamanca, Salamanca, Not set
Hosp. Univ. Marques de Valdecilla, Santander, Not set
Hosp. Virgen Del Rocio, Sevilla, Not set
Hosp. Univ. I Politecni La Fe, Valencia, Not set
Sahlgrenska University Hospital, Goteborg, Not set
Universitetssjukhuset, Linköping, Not set
Skane University Hospital, Lund, Not set
Universitatsspital Basel, Basel, Not set
Inselspital Universitatsspital Bern, Bern, Not set
Kantonsspital St Gallen, St. Gallen, Not set
University Hospitals Birmingham NHS Trust,, Birmingham, Not set
Bristol Royal Infirmary, Bristol, Not set
Leeds Teaching Hospitals NHS Trust, Leeds, Not set
University College Hospital, London, Not set
Kings College Hospital, London, Not set
Manchester Royal Infirmary, Manchester, Not set
The Royal Marsden NHS Trust Sutton, Surrey, Not set
Conditions: Multiple Myeloma
Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)
Completed
The goal of this clinical study is to test how well the study drug, brexucabtagene autoleucel (KTE-X19), works in participants with relapsed/refractory (r/r) mantle cell lymphoma (MCL).
The goal of this clinical study is to test how well the study drug, brexucabtagene autoleucel (KTE-X19), works in participants with relapsed/refractory (r/r) mantle cell lymphoma (MCL). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Banner MD Anderson Cancer Center, Gilbert, Arizona +39 locations
Banner MD Anderson Cancer Center, Gilbert, Arizona
Stanford University, Palo Alto, California
University California Los Angeles (UCLA), Santa Monica, California
Sarah Cannon- Denver, Denver, Colorado
University of Miami, Miami, Florida
Moffitt Cancer Center, Tampa, Florida
Emory University, Atlanta, Georgia
University of Chicago, Chicago, Illinois
Loyola University Medical Center, Maywood, Illinois
Advocate Aurora Health - Advocate Lutheran General Hospital, Park Ridge, Illinois
Dana Farber Cancer Institute, Boston, Massachusetts
Karmanos Cancer Institute, Detroit, Michigan
Hackensack University Medical Center, Hackensack, New Jersey
University of Rochester, Rochester, New York
Duke University, Durham, North Carolina
Cleveland Clinic - Taussig Cancer Institute, Cleveland, Ohio
Ohio State University, Columbus, Ohio
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Sarah Cannon - Tenessee, Nashville, Tennessee
Vanderbilt University, Nashville, Tennessee
Baylor Cancer Hospital, Dallas, Texas
MD Anderson Cancer Center, Houston, Texas
Swedish Cancer Institute, Seattle, Washington
CHU de Montpellier, Montpellier CEDEX 05, Not set
Hospital Saint Louis, Paris, Not set
Hopital Haut-Leveque, Pessac, Not set
Centre Hospitalier Lyon Sud, Pierre Benite, Not set
CHU de Rennes, Rennes, Not set
Johannes Gutenberg University Hospital-University Mainz, Mainz, Not set
Munich University of Technology-Medical Faculty- Ethics Committee, München, Not set
Universitaetsklinikum Wuerzburg, Wuerzburg, Not set
Academisch Medisch Centrum, Amsterdam, Not set
University Medical Center Groningen, Groningen, Not set
Erasmus MC, Rotterdam, Not set
Hospital Universitari Vall D'Hebron, Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Hospital Universitario de Salamanca, Salamanca, Not set
Queen Elizabeth University Hospital, Glasgow, Not set
Kings College Hospital, London, Not set
Manchester Royal Infirmary, Manchester, Not set
Conditions: Relapsed/Refractory Mantle Cell Lymphoma
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