Cyclophosphamide Treatment Options in United Kingdom

A collection of 244 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the United Kingdom . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

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A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma

NCT01974440

Completed

The purpose of this study is to evaluate the efficacy and safety of PCI-32765 (ibrutinib) administered in combination with either bendamustine and rituximab (BR) or rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in adult participants with previously treated indolent Non-Hodgkin lymphoma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Not set, Gilbert, Arizona +134 locations

Not set, Gilbert, Arizona

Not set, Campbell, California

Not set, Duarte, California

Not set, La Jolla, California

Not set, Los Angeles, California

Not set, Orange, California

Not set, Ocala, Florida

Not set, Chicago, Illinois

Not set, Maywood, Illinois

Not set, Indianapolis, Indiana

Not set, Westwood, Kansas

Not set, Lexington, Kentucky

Not set, Lafayette, Louisiana

Not set, Scarborough, Maine

Not set, Baltimore, Maryland

Not set, Bethesda, Maryland

Not set, Boston, Massachusetts

Not set, Ann Arbor, Michigan

Not set, Battle Creek, Michigan

Not set, Detroit, Michigan

Not set, Saint Louis Park, Minnesota

Not set, Denville, New Jersey

Not set, New York, New York

Not set, Hickory, North Carolina

Not set, Pinehurst, North Carolina

Not set, Bend, Oregon

Not set, Pittsburgh, Pennsylvania

Not set, Sioux Falls, South Dakota

Not set, Houston, Texas

Not set, Lubbock, Texas

Not set, Spokane, Washington

Not set, Green Bay, Wisconsin

Not set, Buenos Aires, Not set

Not set, Ciudad Autonoma Buenos Aires, Not set

Not set, Cordoba, Not set

Not set, La Capital, Not set

Not set, Mendoza, Not set

Not set, Santa Fe, Not set

Not set, Adelaide, Not set

Not set, Fitzroy, Not set

Not set, Heidelberg, Not set

Not set, South Brisbane, Not set

Not set, Wahroonga, Not set

Not set, Westmead, Not set

Not set, Anderlecht, Not set

Not set, Edegem, Not set

Not set, Gent, Not set

Not set, Leuven, Not set

Not set, Namur, Not set

Not set, Wilrijk, Not set

Not set, Porto Alegre, Not set

Not set, Rio De Janeiro, Not set

Not set, Salvador, Not set

Not set, Sao Paulo, Not set

Not set, Beijing, Not set

Not set, Chengdu, Not set

Not set, Guangzhou, Not set

Not set, Hangzhou, Not set

Not set, Harbin, Not set

Not set, Nanjing, Not set

Not set, Shanghai, Not set

Not set, Tianjin, Not set

Not set, Nice Cedex 2, Not set

Not set, Paris, Not set

Not set, Pessac, Not set

Not set, Pierre Benite, Not set

Not set, Rennes, Not set

Not set, Berlin, Not set

Not set, Gießen, Not set

Not set, Göttingen, Not set

Not set, Ludwigshafen, Not set

Not set, Magdeburg, Not set

Not set, Mainz, Not set

Not set, Munchen, Not set

Not set, Wiesbaden, Not set

Not set, Hadera, Not set

Not set, Haifa, Not set

Not set, Jerusalem, Not set

Not set, Nahariya, Not set

Not set, Netanya, Not set

Not set, Petah Tikva, Not set

Not set, Ramat Gan, Not set

Not set, Chuo Ku, Not set

Not set, Hiroshima shi, Not set

Not set, Isehara, Not set

Not set, Kobe, Not set

Not set, Nagoya-shi, Not set

Not set, Osaka Sayama shi, Not set

Not set, Sapporo-shi, Not set

Not set, Sendai shi, Not set

Not set, Suita-shi, Not set

Not set, Tokyo, Not set

Not set, Jeollanam-do, Not set

Not set, Seoul, Not set

Not set, Gdynia, Not set

Not set, Olsztyn, Not set

Not set, Warszawa, Not set

Not set, Bayamon, Not set

Not set, Ponce, Not set

Not set, San Juan, Not set

Not set, Krasnodar, Not set

Not set, Moscow, Not set

Not set, Nizny Novgorod, Not set

Not set, Petrozavodsk, Not set

Not set, Pyatigorsk, Not set

Not set, Rostov-On-Don, Not set

Not set, St. Petersburg, Not set

Not set, Syktyvkar, Not set

Not set, Volgograd, Not set

Not set, Barcelona, Not set

Not set, Madrid, Not set

Not set, Pozuelo de Alarcon, Not set

Not set, Salamanca, Not set

Not set, Göteborg, Not set

Not set, Linköping, Not set

Not set, Luleå, Not set

Not set, Uppsala, Not set

Not set, Ankara, Not set

Not set, Antalya, Not set

Not set, Istanbul, Not set

Not set, Izmir, Not set

Not set, Kayseri, Not set

Not set, Cherkasy, Not set

Not set, Ivano-Frankivsk, Not set

Not set, Khmelnitskiy, Not set

Not set, Kiev, Not set

Not set, Lviv, Not set

Not set, Uzhgorod, Not set

Not set, Glasgow, Not set

Not set, London, Not set

Not set, Newcastle upon Tyne, Not set

Not set, Plymouth, Not set

Not set, Portsmouth, Not set

Not set, Sutton, Not set

Not set, Swansea, Not set

Conditions: Lymphoma

Learn More ›

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

NCT03384654

Completed

The purpose of this study is to evaluate the efficacy of daratumumab in addition to standard chemotherapy in pediatric participants with relapsed/refractory B-cell acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LL) and T-cell ALL/LL as measured by the complete response (CR) rate.

Gender:

ALL

Ages:

Between 1 year and 30 years

Trial Updated:

05/22/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +52 locations

University of Alabama at Birmingham, Birmingham, Alabama

Phoenix Children's Hospital, Phoenix, Arizona

UCSF Benioff Children's Hospital Oakland, Oakland, California

Children's Hospital Orange County, Orange, California

Stanford University, Palo Alto, California

Children's Hospital Colorado, Aurora, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Children'S Healthcare Of Atlanta/Emory Univ. Dept. Of Pediatrics, Atlanta, Georgia

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Johns Hopkins University, Baltimore, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

C.S. Mott Children's Hospital, Ann Arbor, Michigan

Washington Univeristy School of Medicine/ Pediatrics, Saint Louis, Missouri

Newark Beth Israel Medical Center, Newark, New Jersey

New York University Langone Medical Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Stony Brook University Medical Center, Stony Brook, New York

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Dell Children's Medical Center of Central Texas/Children's Blood and Cancer Center, Austin, Texas

UT Southwestern Medical Center, Dallas, Texas

Baylor College of Medicine, Houston, Texas

University of Utah Primary Children's Medical Center, Salt Lake City, Utah

Medical College Of Wisconsin, Milwaukee, Wisconsin

Universitair Ziekenhuis Gent - UZ GENT, Gent, Not set

CHU de Bordeaux, Hopital des Enfants, Bordeaux, Not set

IHOPE - Hospices civils de Lyon, Lyon, Not set

Hopital trousseau- APHP, Paris, Not set

Hôpital Robert Debré, Paris, Not set

Hôpital D'Enfants, Vandoeuvre les Nancy, Not set

Charite-Universitätsmedizin Berlin - Berlin, Berlin, Not set

Medizinische Hochschule Hannover, Hannover, Not set

Universitatsklinikum Munster, Münster, Not set

Schneider Children's Medical Center, Petach Tiquva, Not set

Istituto Giannina Gaslini, Genova, Not set

Fondazione MBBM, ASST Monza, Monza, Not set

Ospedale Pediatrico Bambin Gesù, Roma, Not set

AOU Città della Salute e della Scienza di Torino, Presidio Ospedale Infantile Regina Margherita, Torino, Not set

Princess Maxima Center, Utrecht, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp. Sant Joan de Deu, Esplugues de Llobregat, Not set

Hosp. Infantil Univ. Nino Jesus, Madrid, Not set

Hosp. Univ. I Politecni La Fe, Valencia, Not set

Karolinska University Hospital, Stockholm, Not set

Bristol Royal Hospital for Children, Bristol, Not set

Royal Hospital for Sick Children, Glasgow, Not set

Leeds Children's Hospital, Leeds, Not set

University College London Hospitals, London, Not set

Great Ormond Street Hospital, London, Not set

Royal Manchester Children's Hospital, Manchester, Not set

Royal Marsden Hospital, Surrey, Not set

Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma

Learn More ›

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

NCT03201965

Completed

The purpose of this study is to evaluate the efficacy and safety of daratumumab plus cyclophosphamide, bortezomib and dexamethasone (CyBorD) compared with CyBorD alone in treatment of newly diagnosed amyloid light chain (AL) amyloidosis participants.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Mayo Clinic Arizona, Phoenix, Arizona +139 locations

Mayo Clinic Arizona, Phoenix, Arizona

City of Hope, Duarte, California

University of California San Francisco, San Francisco, California

Stanford University, Stanford, California

University of Colorado, Aurora, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Mayo Clinic, Jacksonville, Florida

Winship Cancer Institute Emory University, Atlanta, Georgia

University of Maryland, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Boston University Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

Washington University School Of Medicine, Saint Louis, Missouri

Columbia University Medical Center, New York, New York

Weill Cornell Medical College, New York, New York

University of Rochester Medical Center, Rochester, New York

Levine Cancer Institute, Charlotte, North Carolina

Wake Forest University Health Sciences - Cardiovascular Medicine, Winston-Salem, North Carolina

Cleveland Clinic, Cleveland, Ohio

The Ohio State University, Columbus, Ohio

Oregon Health And Science University, Portland, Oregon

University of Pennsylvania Medical Center, Philadelphia, Pennsylvania

Sarah Cannon Research Institute, Nashville, Tennessee

Vanderbilt University Medical Center, Nashville, Tennessee

University of Texas, MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Seattle Cancer Care Alliance, Seattle, Washington

Box Hill Hospital, Box Hill, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Westmead Hospital, Westmead, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Institut Jules Bordet, Anderlecht, Not set

UZ Gent, Gent, Not set

Az Groeninge, Kortrijk, Not set

Universitair Ziekenhuis Leuven, Leuven, Not set

Hospital das Clinicas de Porto Alegre, Porto Alegre, Not set

Sociedade Pernambucana de Combate ao Cancer, Recife, Not set

Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI), Rio de Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set

Instituto de Assistencia Medica ao Servidor Publico Estadual IAMSPE, Sao Paulo, Not set

Clinica Sao Germano, São Paulo, Not set

Hospital Das Clinicas Da Faculdade De Medicina Da USP, São Paulo, Not set

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Alberta Health Services, Edmonton, Alberta

Vancouver General Hospital, Vancouver, British Columbia

London Health Sciences Center, London, Ontario

University Health Network UHN Princess Margaret Cancer Centre, Toronto, Ontario

McGill University Health Centre, Montreal, Quebec

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Aarhus University Hospital, Aarhus N, Not set

Dep. of Hematology, Rigshospitalet, Copenhagen, Not set

Odense Universitets Hospital, Odense, Not set

CHU Dijon, Dijon, Not set

Hopital Claude Huriez, Lille cedex, Not set

CHU de Limoges - Fédération Hépatologie, Limoges, Not set

Institut Paoli Calmettes, Marseille, Not set

Chu Hotel Dieu, Nantes cedex 01, Not set

Hopital Saint Louis, PARIS cedex 10, Not set

Centre hospitalier Lyon-Sud, Pierre - Bénite cedex, Not set

CHU De Poitiers, Poitiers, Not set

CHU Rangueil, Toulouse, Not set

CHU Bretonneau, Tours cedex, Not set

CHU de Nancy_ Hopital Brabois, Vandoeuvre les Nancy, Not set

Charite Campus Benjamin Franklin, Berlin, Not set

Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Not set

Universitatsklinikum Essen, Essen, Not set

HOPA-Hämatologisch-Onkologische Praxis Altona MVZ GmbH, Hamburg, Not set

Universitaetsklinikum Heidelberg Medizinische Klinik V, Heidelberg, Not set

Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,, Tübingen, Not set

Universitätsklinikum Würzburg Med. Klinik U. Poliklinik Ii, Würzburg, Not set

Alexandra General Hospital of Athens, Athens, Not set

University General Hospital of Rio, Patra, Not set

Semmelweis Egyetem I.Belgyogyaszati Klinika, Budapest, Not set

Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely, Budapest, Not set

Carmel Hospital, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Sheba Medical Center, Ramat-Gan, Not set

Sourasky Medical Center, Tel-Aviv, Not set

Assaf Ha'Rofeh Medical Center, Zerifin, Not set

Policlinico di Bari, Bari, Not set

Istituto di Ematologia Seràgnoli azienda ospedaliera univeristaria Policlinico S.Orsola-Malpighi, Bologna, Not set

Casa di Cura La Maddalena, Palermo, Not set

Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Dipartimento Di Biotecnologie Cellulari Ed Ematologia-Università ''La Sapienza'',Policlinico Umberto I, Roma, Not set

A.O.U. Città della Salute e della Scienza, Torino, Not set

Fukushima Medical University Hospital, Fukushima, Not set

Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Not set

Teine Keijinkai Hospital, Hokkaido, Not set

Kanazawa University Hospital, Kanazawa, Not set

Kumamoto University Hospital, Kumamoto-City, Not set

Kyoto Kuramaguchi Medical Center, Kyoto, Not set

Shinshu University Hospital, Matsumoto, Not set

Matsuyama Red Cross Hospital, Matsuyama, Not set

Nagoya City University Hospital, Nagoya, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Japanese Red Cross Medical Center, Shibuya, Not set

Tokushima University Hospital, Tokushima, Not set

Pusan National University Hospital, Busan, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

Centro de Investigación Farmacéutica Especializada, Guadalajara, Not set

Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Not set

Haga ziekenhuis, Den Haag, Not set

UMCG, Groningen, Not set

Erasmus MC, Rotterdam, Not set

UMC Utrecht, Utrecht, Not set

Maxima Medisch Centrum, Veldhoven, Not set

Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich, Chorzow, Not set

SKPP UM w Poznaniu, Poznan, Not set

Instytut Hematologii i Transfuzjologii, Warszawa, Not set

Inst. Cat. D'Oncologia-Badalona, Badalona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp Univ Fund Jimenez Diaz, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. de Canarias, San Cristóbal de La Laguna, Not set

Hosp. Univ. Dr. Peset, Valencia, Not set

South Elvsborg Hospital, Boras, Not set

Skanes universitetssjukhus, Lund, Not set

Ankara Universitesi Tip Fakultesi Cebeci Hastanesi, Ankara, Not set

Akdeniz University Medical Faculty, Antalya, Not set

Ondokuz Mayis Universitesi Tip Fakultesiy, Atakum, Not set

Istanbul University Istanbul Medical Faculty, Istanbul, Not set

Dokuz Eylul Universitesi Tip Fakultesi, Izmir, Not set

Erciyes University Medical Faculty, Talas, Not set

University Hospitals Birmingham NHS Trust,, Birmingham, Not set

University College Hospital, London, Not set

Conditions: Amyloidosis

Learn More ›

A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)

NCT04504825

Active Not Recruiting

AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous system and digestive tract. The primary purpose of this study is to determine whether CAEL-101, a monoclonal antibody that removes AL amyloid deposits from tissues and organs, improves... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Research Site, Duarte, California +89 locations

Research Site, Duarte, California

Research Site, Palo Alto, California

Research Site, San Francisco, California

Research Site, Weston, Florida

Research Site, Indianapolis, Indiana

Research Site, New Orleans, Louisiana

Research Site, Boston, Massachusetts

Research Site, Detroit, Michigan

Research Site, Rochester, Minnesota

Research Site, Saint Louis, Missouri

Research Site, New York, New York

Research Site, Rochester, New York

Research Site, Winston-Salem, North Carolina

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Portland, Oregon

Research Site, Philadelphia, Pennsylvania

Research Site, Nashville, Tennessee

Research Site, Dallas, Texas

Research Site, Houston, Texas

Research Site, Salt Lake City, Utah

Research Site, Seattle, Washington

Research Site, Milwaukee, Wisconsin

Research Site, Box Hill, Not set

Research Site, Brisbane, Not set

Research Site, Westmead, Not set

Research Site, Linz, Not set

Research Site, Vienna, Not set

Research Site, Anderlecht, Not set

Research Site, Leuven, Not set

Research Site, Porto Alegre, Not set

Research Site, Ribeirão Preto, Not set

Research Site, S.J. Do Rio Preto, Not set

Research Site, Salvador, Not set

Research Site, Calgary, Alberta

Research Site, Edmonton, Alberta

Research Site, Toronto, Ontario

Research Site, Beijing, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Wenzhou, Not set

Research Site, Wuhan, Not set

Research Site, Ostrava - Poruba, Not set

Research Site, Prague, Not set

Research Site, Caen, Not set

Research Site, Creteil, Not set

Research Site, Limoges, Not set

Research Site, Marseille, Not set

Research Site, Paris, Not set

Research Site, Pessac, Not set

Research Site, Pierre-Benite, Not set

Research Site, Poitiers, Not set

Research Site, Rennes, Not set

Research Site, Toulouse, Not set

Research Site, Tours, Not set

Research Site, Berlin, Not set

Research Site, Duesseldorf, Not set

Research Site, Essen, Not set

Research Site, Hamburg, Not set

Research Site, Heidelberg, Not set

Research Site, Wuerzburg, Not set

Research Site, Athens, Not set

Research Site, Rio, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Tel Hashomer, Not set

Research Site, Napoli, Not set

Research Site, Pavia, Not set

Research Site, Pisa, Not set

Research Site, Roma, Not set

Research Site, Fukushima-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Shibuya-ku, Not set

Research Site, Seoul, Not set

Research Site, Groningen, Not set

Research Site, Utrecht, Not set

Research Site, Gdańsk, Not set

Research Site, Poznan, Not set

Research Site, Warszawa, Not set

Research Site, Barcelona, Not set

Research Site, Gijón, Not set

Research Site, Majadahonda, Not set

Research Site, Pamplona, Not set

Research Site, Sevilla, Not set

Research Site, London, Not set

Conditions: AL Amyloidosis

Learn More ›

A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)

NCT04512235

Active Not Recruiting

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/22/2025

Locations: Research Site, Scottsdale, Arizona +109 locations

Research Site, Scottsdale, Arizona

Research Site, Duarte, California

Research Site, Palo Alto, California

Research Site, San Francisco, California

Research Site, Jacksonville, Florida

Research Site, Weston, Florida

Research Site, Indianapolis, Indiana

Research Site, New Orleans, Louisiana

Research Site, Baltimore, Maryland

Research Site, Boston, Massachusetts

Research Site, Detroit, Michigan

Research Site, Rochester, Minnesota

Research Site, Saint Louis, Missouri

Research Site, New York, New York

Research Site, Rochester, New York

Research Site, Chapel Hill, North Carolina

Research Site, Durham, North Carolina

Research Site, Winston-Salem, North Carolina

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Portland, Oregon

Research Site, Philadelphia, Pennsylvania

Research Site, Nashville, Tennessee

Research Site, Dallas, Texas

Research Site, Houston, Texas

Research Site, Salt Lake City, Utah

Research Site, Seattle, Washington

Research Site, Madison, Wisconsin

Research Site, Milwaukee, Wisconsin

Research Site, Box Hill, Not set

Research Site, Murdoch, Not set

Research Site, Westmead, Not set

Research Site, Woolloongabba, Not set

Research Site, Linz, Not set

Research Site, Vienna, Not set

Research Site, Anderlecht, Not set

Research Site, Leuven, Not set

Research Site, Porto Alegre, Not set

Research Site, Ribeirão Preto, Not set

Research Site, Salvador, Not set

Research Site, Calgary, Alberta

Research Site, Toronto, Ontario

Research Site, Beijing, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Shanghai, Not set

Research Site, Suzhou, Not set

Research Site, Wenzhou, Not set

Research Site, Wuhan, Not set

Research Site, Ostrava Poruba, Not set

Research Site, Prague, Not set

Research Site, Caen, Not set

Research Site, Creteil, Not set

Research Site, Dijon, Not set

Research Site, Lille, Not set

Research Site, Limoges, Not set

Research Site, Marseille, Not set

Research Site, Paris, Not set

Research Site, Pessac, Not set

Research Site, Pierre Benite, Not set

Research Site, Poitiers, Not set

Research Site, Rennes, Not set

Research Site, Toulouse, Not set

Research Site, Tours, Not set

Research Site, Berlin, Not set

Research Site, Düsseldorf, Not set

Research Site, Essen, Not set

Research Site, Hamburg, Not set

Research Site, Heidelberg, Not set

Research Site, Wuerzburg, Not set

Research Site, Athens, Not set

Research Site, Rio, Not set

Research Site, Thessaloniki, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Petah Tikva, Not set

Research Site, Tel Aviv, Not set

Research Site, Tel Hashomer, Not set

Research Site, Brescia, Not set

Research Site, Fukushima-shi, Not set

Research Site, Kanazawa-shi, Not set

Research Site, Kashiwa-shi, Not set

Research Site, Kita-ku, Not set

Research Site, Kumamoto-shi, Not set

Research Site, Matsumoto-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Shibuya-ku, Not set

Research Site, Seoul, Not set

Research Site, Gdańsk, Not set

Research Site, Warszawa, Not set

Research Site, St. Petersburg, Not set

Research Site, Barcelona, Not set

Research Site, Gijón, Not set

Research Site, Granada, Not set

Research Site, Madrid, Not set

Research Site, Majadahonda, Not set

Research Site, Pamplona, Not set

Research Site, Salamanca, Not set

Research Site, Sevilla, Not set

Research Site, Valencia, Not set

Research Site, Glasgow, Not set

Research Site, London, Not set

Conditions: AL Amyloidosis

Learn More ›

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

NCT02303821

Completed

The purpose of Phase 1b of this study is to: * Asses the safety, tolerability and activity of carfilzomib, alone and in combination with induction chemotherapy, in children with relapsed or refractory acute lymphoblastic leukemia (ALL). * Determine the maximum tolerated dose (MTD) and to recommend a phase 2 dose of carfilzomib in combination with induction chemotherapy. The purpose of Phase 2 of this study is to compare the rate of complete remission (CR) of carfilzomib in combination with vin... Read More

Gender:

ALL

Ages:

Between 1 month and 21 years

Trial Updated:

05/16/2025

Locations: University of California San Francisco Benioff Childrens Hospital Oakland, Oakland, California +121 locations

University of California San Francisco Benioff Childrens Hospital Oakland, Oakland, California

Childrens Hospital of Orange County, Orange, California

Childrens Hospital Colorado, Aurora, Colorado

Childrens Healthcare of Atlanta, Egleston, Atlanta, Georgia

Lurie Childrens Hospital of Chicago, Chicago, Illinois

The Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore, Maryland

Childrens Hospital and Clinics of Minnesota, Minneapolis, Minnesota

Childrens Mercy Hospital, Kansas City, Missouri

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Childrens Hospital of New York Presbyterian, New York, New York

Levine Childrens Hospital at Carolinas Medical Center d/b/a Atrium Health, Charlotte, North Carolina

Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio

The Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Childrens Hospital, Columbus, Ohio

Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Judes Childrens Research Hospital, Memphis, Tennessee

Childrens Medical Center, Dallas, Texas

Texas Childrens Hospital West Tower, Houston, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

University of Utah Medical Center Primary Childrens Medical Center, Salt Lake City, Utah

West Virginia University Medicine Childrens, Morgantown, West Virginia

Medical College of Wisconsin, Milwaukee, Wisconsin

Hospital Aleman, Ciudad Autonoma de Buenos Aires, Buenos Aires

Hospital Italiano de Buenos Aires, Ciudad Autonoma de Buenos Aires, Buenos Aires

Hospital Universitario Austral, Pilar, Buenos Aires

Sydney Childrens Hospital, Randwick, New South Wales

The Childrens Hospital at Westmead, Westmead, New South Wales

Queensland Childrens Hospital, South Brisbane, Queensland

The Royal Childrens Hospital, Parkville, Victoria

Perth Childrens Hospital, Nedlands, Western Australia

St Anna Kinderspital, Wien, Not set

Hospital São Rafael - IDOR, Salvador, Bahia

Hospital da Crianca de Brasília, Brasília, Distrito Federal

Liga Paranaense do Combate ao Cancer - Hospital Erasto Gaertner, Curitba, Paraná

Hospital Pequeno Principe, Curitiba, Paraná

Instituto de Medicina Integral Professor Fernando Figueira, Recife, Pernambuco

Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Hospital da Crianca Santo Antonio Irmandade Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Fundacao Pio 12 Hospital de Amor de Barretos, Barretos, São Paulo

Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo, Ribeirao Preto, São Paulo

Itaci Instituto de Tratamento do Cancer Infantil, Sao Paulo, São Paulo

Beneficencia Portuguesa de Sao Paulo, São Paulo, Not set

University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna-ISUL EAD, Sofia, Not set

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Hospital Luis Calvo Mackenna, Santiago de Chile, Not set

Hospital Roberto del Rio, Santiago, Not set

Sociedad de Oncologia y Hematologia del Cesar, Valledupar, Cesar

Clinica Imbanaco S.A.S, Cali, Valle Del Cauca

Fakultni nemocnice Brno, Brno, Not set

University Hospital Rigshospitalet, Kobenhavn O, Not set

Centre Hospitalier Universitaire de Bordeaux - Hopital Pellegrin, Bordeaux Cedex, Not set

Centre Hospitalier Regional Universitaire de Lille, Lille, Not set

Hopital Armand Trousseau, Paris, Not set

Hopital Robert Debre, Paris, Not set

Centre Hospitalier Universitaire de Toulouse - Hopital des enfants, Toulouse Cedex 9, Not set

Centre Hospitalier Universitaire de Nancy - Hopital Enfants de Brabois, Vandoeuvre les Nancy Cedex, Not set

Agia Sofia Children Hospital, Athens, Not set

Agia Sofia Children Hospital, Goudi, Not set

General Children Hospital Panagioti and Aglaias Kyriakou, Goudi, Not set

General University Hospital of Patras Panagia i Voithia, Patra, Not set

Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Not set

Hong Kong Childrens Hospital, Kowloon Bay, Not set

Sheba Medical Center, Tel Hashomer, Not set

Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari, Bari, Not set

Azienda Ospedaliera Universitaria Policlinico Vittorio Emanuele Presidio Ospedaliero G Rodolico, Catania, Not set

IRCCS Istituto Giannina Gaslini, Genova, Not set

Fondazione IRCCS San Gerardo dei Tintori, Monza (MB), Not set

Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon, Napoli, Not set

Azienda Ospedaliera di Padova, Padova, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

IRCCS Ospedale Pediatrico Bambino Gesu, Roma, Not set

Azienda Ospedaliera Citta della Salute e della Scienza Torino Ospedale Infantile Regina Margherita, Torino, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Pusan National University Yangsan Hospital, Yangsan-si, Gyeongsangnam-do, Not set

BRCR Global Mexico, Mexico, Distrito Federal

Instituto Nacional de Pediatria, Mexico, Distrito Federal

BRCR Global Mexico, Guadalajara, Jalisco

BRCR Global Mexico, Puebla, Not set

Prinses Maxima Centrum voor Kinderoncologie, Utrecht, Not set

Oslo Universitetssykehus Rikshospitalet, Oslo, Not set

Uniwersytecki Szpital Dzieciecy w Krakowie, Krakow, Not set

CSK Uniwersytetu Medycznego w Lodzi Uniwersyteckie Centrum Pediatrii im Marii Konopnickiej, Lodz, Not set

Uniwersytecki szpital dzieciecy, Lublin, Not set

Uck wum dzieciecy szpital kliniczny im jozefa polikarpa brudzinskiego, Warszawa, Not set

Uniwersytecki Szpital Kliniczny im Jana Mikulicza-Radeckiego we Wroclawiu, Wroclaw, Not set

SPSK nr 1 im Prof Stanislawa Szyszko Slaskiego Uniwersytetu Medycznego w Katowicach, Zabrze, Not set

Centro Hospitalar Universitario de Coimbra, Coimbra, Not set

Instituto Portugues de Oncologia de Lisboa Francisco Gentil, EPE, Lisboa, Not set

Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set

Institutul Clinic Fundeni, Bucharest, Not set

Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca, Cluj Napoca, Not set

Spitalul Clinic de Urgenta pentru Copii Louis Turcanu Timisoara, Timisoara, Not set

FSBI N N Blokhin Russian Oncology Research Center Ministry of Health of Russian Federation, Moscow, Not set

FSBI FSCC of pediatric hematology, oncology and immunology n a Dmitry Rogachev, Moscow, Not set

SBEI of HPE Saint Petersburg State Medical University na academic I P Pavlov of MoH of RF, Saint Petersburg, Not set

King Fahad Medical City, Riyadh, Not set

National University Hospital, Singapore, Not set

KK Womens and Childrens Hospital, Singapore, Not set

Chris Hani Baragwanath Hospital, Johannesburg, Not set

Hospital Sant Joan de Deu, Esplugues de Llobregat, Cataluña

Hospital Universitario Infantil Niño Jesus, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Karolinska Universitetssjukhuset Solna, Solna, Not set

National Taiwan University Hospital, Taipei, Not set

Mackay Memorial Hospital Taipei Branch, Taipei, Not set

Linkou Chang Gung Memorial Hospital, Taoyuan, Not set

King Chulalongkorn Memorial Hospital, Bangkok, Not set

Phramongkutklao Hospital, Bangkok, Not set

Ramathibodi Hospital, Bangkok, Not set

Siriraj Hospital, Bangkok, Not set

Acibadem Adana Hastanesi, Adana, Not set

Ankara Universitesi Tip Fakultesi Hastanesi, Ankara, Not set

Ankara Bilkent Sehir Hastanesi, Ankara, Not set

Medical Park Antalya Hastanesi, Antalya, Not set

Bursa Uludag Universitesi Tip Fakultesi, Bursa, Not set

Medical Park Bahcelievler Hastanesi, Istanbul, Not set

Medipol Mega Universite Hastanesi, Istanbul, Not set

Ege Universitesi Tip Fakultesi, Izmir, Not set

Erciyes Universitesi Tip Fakultesi Mustafa Eraslan ve Fevzi Mercan Cocuk Hastanesi, Kayseri, Not set

The Royal Marsden NHS Foundation Trust, Sutton, Not set

Conditions: Acute Lymphoblastic Leukemia (ALL)

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A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Patients With Previously Untreated Diffuse Large B-cell Lymphoma

NCT06091865

Active Not Recruiting

This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with diffuse large B-cell lymphoma (DLBCL) that have not been treated before (called "previously untreated"). Patients with DLBCL that have come back after treatment (called "relapsed"), or have not responded to treatment (called "refractory"), can also participate in this study. This study will be made up of Part 1A, Part 1B... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/12/2025

Locations: David Geffen School of Medicine at UCLA, Los Angeles, California +148 locations

David Geffen School of Medicine at UCLA, Los Angeles, California

University of California Irvine Medical Center, Orange, California

University of California (UC) Davis, Sacramento, California

Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana

St Vincent Ascension at Peyton Manning Childrens Hospital, Indianapolis, Indiana

Investigative Clinical Research of Indiana, Noblesville, Indiana

University of Kentucky, Lexington, Kentucky

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Henry Ford Health System, Detroit, Michigan

Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Stony Brook University Hospital, Stony Brook, New York

Clinical Research Alliance Inc, Westbury, New York

Duke University Medical Center, Durham, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Center for Oncology and Blood Disorders, Houston, Texas

Community Cancer Trials of Utah, Ogden, Utah

Prohealth Care Inc, Waukesha, Wisconsin

Liverpool Hospital, Liverpool, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Icon Cancer Centre - Wesley, Auchenflower, Queensland

Pindara Private Hospital, Benowa, Queensland

Epworth Freemasons, East Melbourne, Victoria

Landeskrankenhaus Hochsteiermark, Leoben, Styria

Kepler University Hospital, Linz, Upper Austria

Medical University Graz, Graz, Not set

Medical University of Vienna, Vienna, Not set

Hanusch Krankenhaus, Vienna, Not set

Klinikum Wels-Grieskirchen, Wels, Not set

AZ St.-Elisabeth Herentals vzw, Herentals, Antwerp

Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital, Gent, Oost-Vlaanderen

Az Delta, Roeselare, West Vlaanderen

Institut Jules Bordet, Brussels, Not set

Centre Hospitalier Regional de Verviers, Verviers, Not set

Hospital Clinico Universidad de Los Andes, Santiago, Las Condes

Inmunocel, Santiago, Region Metropolitana

Clinica Alemana de Santiago, Santiago, Not set

University Hospital Hradec Kralove, Hradec Kralove, East Bohemia

University Hospital Kralovske Vinohrady, Prague, Not set

Vseobecna Fakultni Nemocnice V Praze, Praha, Not set

Centre Hospitalier Universitaire (CHU) Rennes, Rennes, Bretagne

CHRU de Tours, Tours, Centre Val De Loire

Polyclinique Bordeaux Nord Aquitaine, Bordeaux Cedex, Gironde

Hopital Victor Dupouy Argenteuil, Argenteuil, Ile De France

Avicenne Hospital, Bobigny, Ile De France

Hopital Saint Vincent-de-Paul, Lille, Nord

CHU de Poitiers, Poitiers, Nouvelle Aquitaine

Centre Hospitalier Universitaire (CHU) de Bordeaux, Pessac, Nouvelle-Aquitaine

Nantes University Hospital, Nantes, Pays De La Loire

Centre Hospitalier Metropole Savoie, Chambery, Savoie

Gustave Roussy, Villejuif, Val De Marne / Ile De France

Centre Hospitalier Universitaire Angers, Angers, Not set

Change Annecy, Metz Tessy, Not set

CHU Nimes Institut de Cancerologie, Nimes, Not set

Assistance Publique-Hopitaux de Paris (AP-HP), Paris, Not set

CHU de Saint-Etienne, Saint-Etienne, Not set

Robert-Bosch-Krankenhaus, Stuttgart, Baden-Wurttemberg

Kliniken Ostalb Stauferklinikum Schwab Gmund, Mutlangen, Gmund

Clinic Frankfurt (Oder), Frankfurt, Hesse

University Hospital Essen, Essen, Nordrhein Westfalen

Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz KoeR, Mainz, Rheinland-Pfalz

Hematological Praxis Dresden, Dresden, Sachsen

University Hospital Carl Gustav Carus, Dresden, Not set

Stadtisches Krankenhaus Kiel, Kiel, Not set

Beaumont Hospital, Dublin, Leinster

St James Hospital and Trinity College Dublin, Dublin, Not set

The Chaim Sheba Medical Center, Tel-Hashomer, Tel Aviv

Samson Assuta Ashdod University Hospital, Ashdod, Not set

Bnai Zion Medical Center, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Galilee Medical Center, Nahariya, Not set

The Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola (fc), Forli Cesena

ASST Monza Ospedale San Gerardo, Monza, Lombardy

Istituto Europeo di Oncologia, Milano, Not set

A.O.U. di Modena, Modena, Not set

Federico II University, Napoli, Not set

AOU Maggiore della Carita, Novara, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Azienda Ospedaliera di Perugia, Perugia, Not set

Ospedale Santa Maria delle Croci, Ravenna, Not set

Hematology - Città della Salute e della Scienza di Torino, Turin, Not set

Santa Maria della Misericordia, Udine, Not set

St. Vincent Hospital - The Catholic University of Korea, Suwon-si, Gyeonggi-do

Gachon University Gil Medical Center, Incheon, Namdong-Gu

Inje University Busan Paik Hospital, Busan, Not set

Dong-A University Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Yeyungnam University Medical Center, Daegu, Not set

Keimyung University Dongsan Hospital, Daegu, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Yeouido St. Marys Hospital, Seoul, Not set

Seoul St Marys Hospital, Seoul, Not set

Hospital Ampang, Ampang, Pahang

Hospital Tg Ampuan Afzan, Kuantan, Pahang

Hospital Queen Elizabeth, Kota Kinabalu, Sabah

Subang Jaya Medical Center, Subang Jaya, Selangor

University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Uniwersytecki Szpital Kliniczny, Wroclaw, Dolnoslaskie

Matopolskie Centrum Medyczne S.C., Krakow, Malopolskie

Pratia Poznan Medical Center, Poznan, Wielkopolska

Szpital Uniwersytecki Nr2 Bydgoszcz, Bydgoszcz, Not set

Uniwersyteckie Centrum Kliniczne, Building of the Non-Invasive Medicine Center, Gdansk, Not set

Centrum Innowacyjnych Terapii Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set

Szpital Szpecjalistyczny w Walbrzychu, Walbrzych, Not set

National University Hospital Singapore, Singapore, Not set

National Cancer Centre of Singapore, Singapore, Not set

Tan Tock Seng Hospital, Singapore, Not set

Hospital Clinico Universitario Santiago de Compostela, Santiago de Compostela, A Coruna

Hospital Universitario Central De Asturias, Oviedo, Asturias

Son Espases University Hospital, Palma, Balearic Islands

Hospital Universitari Parc Tauli, Sabadell, Barcelona

Hospital Universitari Mutua Terrassa, Terrassa, Barcelona

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Madrid

Hospital Universitario de Navarra, Pamplona, Navarra

Hospital Sant Pau, Barcelona, Not set

Hospital Virgen De Las Nieves De Granada, Granada, Not set

Hospital Universitario Infanta Leonor, Madrid, Not set

Hospital Universitario Ramon y Cajal, Madrid, Not set

Fundacion Jimenez Diaz University Hospital, Madrid, Not set

Hospital Universitario HM Sanchinarro, Servicio de Hematologia, Madrid, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital General Universitario de Toledo, Toledo, Not set

Instituto Valenciano de Oncologia, Valencia, Not set

University Hospital Doctor Peset, Valencia, Not set

Changhua Christian Hospital, Changhua City, Not set

Taipei Medical University - Shuang Ho Hospital, New Taipei City, Not set

Chang Gung Medical Foundation Chia Yi Branch, Puzi City, Not set

National Taiwan University Hospital, Taipei City, Not set

Wanfang Hospital, Taipei, Not set

Chang Gung Memorial Hospital- Linkou Branch, Taoyuan, Not set

Chulalongkorn University, Bangkok, Krung Thep Maha Nakhon [Bangko]

Sriraj Hospital, Bangkok, Not set

Chaing Mai University, Chiang Mai, Not set

Faculty of Medicine, Khon Kaen, Not set

Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Yenimahalle, Ankara

VM Medical Park Mersin Hospital, Mezitli, Mersin

Tekirdag Namik Kemal University Hospital, Tekirdag, Suleymanpasa

Gazi Universitesi, Besevler, Not set

Istanbul University Istanbul Faculty of Medicine, Istanbul, Not set

Ege University, Izmir, Not set

Dokuz Eylul University, Izmir, Not set

Sakarya Universty Medical Faculty, Sakarya, Not set

Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi, Samsun, Not set

NHS Grampian: Aberdeen Royal Infirmary, Aberdeen, Not set

The Hillingdon Hospitals NHS Foundation Trust, Uxbridge, Not set

Conditions: Diffuse Large B-cell Lymphoma (DLBCL)

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Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma

NCT05371093

Active Not Recruiting

The goal of this clinical study is test how well the study drug, axicabtagene ciloleucel, works in participants with relapsed/refractory follicular lymphoma

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/07/2025

Locations: City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte, California +51 locations

City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte, California

Stanford Health Care, Stanford, California

Moffitt Cancer Center, Tampa, Florida

The University of Kansas Hospital, Westwood, Kansas

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

Novant Health Cancer Institute Hematology - Charlotte, Charlotte, North Carolina

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

TriStar Centennial Medical Center - Cell Processing, Nashville, Tennessee

Henry-Joyce Cancer Clinic, Nashville, Tennessee

The University of Texas MD Anderson Cancer Center, Houston, Texas

Virginia Commonwealth University, Richmond, Virginia

Hopital Henri Mondor, Créteil, Not set

CHU de Dijon, Dijon, Not set

Hôpital Claude Huriez-CHU de Lille, Lille cedex, Not set

Institut Paoli-Calmettes, Marseille, Not set

Hopital Saint Eloi, Montpellier, Not set

Hopital Pitie-Salpetriere, Paris, Not set

CHU Bordeaux - Hospital Haut-Leveque - Centre Francois Magendie, Pessac, Not set

Centre Hospitalier Lyon Sud, Pierre Benite, Not set

CHU de Poitiers, Poitiers, Not set

Hopital Pontchaillou - CHU Rennes, Rennes, Not set

Centre Henri Becquerel, Rouen, Not set

Universitatsmedizin Gottingen, Göttingen, Not set

Universitatsklinikum Koln Klinik I fur Innere Medizin, Wuerzburg, Not set

ASST Papa Giovanni XXIII, Bergamo, Not set

Azienda Ospedallero-Universitaria di Bologna Policlinico Sant'Orsola-Malpighi, Bologna, Not set

Fondazione IRCCS - Istituto Nazionale Tumori, Milano, Not set

Ospedale San Raffaele, Milano, Not set

Arcispedale Santa Maria Nuova, Reggio Emilia, Not set

Istituto Clinico Humanitas-IRCCS, Rozzano, Not set

Hyogo Medical University Hospital, Hyogo, Not set

University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set

Tohoku University Hospital, Miyagi, Not set

Okayama University Hospital, Okayama, Not set

Osaka University Hospital, Osaka, Not set

Hospital Universitari Vall d'Hebrón, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Instituto Catalan de Oncologia - Hospital Duran i Reynolds (ICO L'Hospitalet), Barcelona, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital 12 de Octubre, Madrid, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clínico Universitario de Valencia, Valencia, Not set

University Hospital Birmingham NHS Foundation Trust, Birmingham, Not set

Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set

University College London Hospitals NHS Foundation Trust, London, Not set

King's College Hospital NHS Foundation Trust, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Oxford University Hospitals NHS Foundation Trust, Oxford, Not set

The University Hospital Southampton NHS Foundation Trust, Southampton, Not set

The Royal Marsden NHS Foundation Trust, Sutton, Not set

Conditions: Relapsed/Refractory Follicular Lymphoma

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A Trial Looking at Rituximab and Chemotherapy as a Treatment for Follicular Lymphoma in Elderly Patients

NCT01303887

Completed

The purpose of this study is to determine whether R-FC is more beneficial that R-CVP in the treatment of older patients (aged 60 or over) with Follicular Lymphoma (FL).

Gender:

ALL

Ages:

60 years and above

Trial Updated:

04/16/2025

Locations: Aberdeen Royal Infirmary, Aberdeen, Not set +72 locations

Aberdeen Royal Infirmary, Aberdeen, Not set

Ysbyty Gwynedd, Bangor, Not set

Birmingham Heartlands, Birmingham, Not set

Royal Bournemouth Hospital, Bournemouth, Not set

Bradford Royal Infirmary, Bradford, Not set

Frenchay Hospital, Bristol, Not set

Queen's Hospital, Burton, Burton-upon-Trent, Not set

Addenbrookes Hospital, Cambridge, Not set

Kent and Canterbury Hospital, Canterbury, Not set

Velindre Hospital, Cardiff, Not set

Countess of Chester, Chester, Not set

Leighton Hospital, Crewe, Not set

Trafford General Hospital, Davyhulme, Not set

Russels Hall Hospital, Dudley, Not set

Royal Devon & Exeter Hospital, Exeter, Not set

Falkirk & District Royal Infirmary, Falkirk, Not set

Queen Elizabeth Hospital, Gateshead, Not set

Medway Maritime Hospital, Gillingham, Not set

Beatson Oncology Centre, Glasgow, Not set

Royal Alexandra Hospital, Glasgow, Not set

Harrogate District Foundation Trust, Harrogate, Not set

Northwick Park Hospital, Harrow, Not set

Princess Royal Hospital, Bromley, Hayes, Not set

Huddersfield Royal Infirmary, Huddersfield, Not set

Castle Hill Hospital, Hull, Not set

Raigmore Hospital,, Inverness, Not set

Ipswich Hospital, Ipswich, Not set

Kettering General Hospital, Kettering, Not set

The Queen Elizabeth Hospital, Kings Lynn, Kings Lynn, Not set

St James University Hospital, Leeds, Not set

Leicester Royal Infirmary, Leicester, Not set

Royal Liverpool University Hospital, Liverpool, Not set

University Hospital Aintree, Liverpool, Not set

Altnagelvin Hospital, Londonderry, Not set

Guys & St Thomas Hospital, London, Not set

Kings College Hospital, London, Not set

Royal Free Hospital, London, Not set

St Bartholomews Hospital, London, Not set

University College Hospital, London, Not set

Luton & Dunstable Hospital, Luton, Not set

Kent Oncology Centre, Maidstone, Not set

Manchester Royal Infirmary, Manchester, Not set

The Christie Hospital, Manchester, Not set

Royal Victoria Infirmary, Newcastle upon Tyne, Not set

Northampton General Hospital, Northampton, Not set

Mount Vernon Hospital, Northwood, Not set

Nottingham City Hospital, Nottingham, Not set

Derriford Hospital, Plymouth, Not set

Whiston Hospital, Prescot, Not set

Queens Hospital, Romford, Not set

Salford Royal Hospital, Salford, Not set

Salisbury District Hospital, Salisbury, Not set

Diana Princess of Wales Hospital, Scunthorpe, Not set

Royal Hallamshire Hospital, Sheffield, Not set

Wexham Park Hospital, Slough, Not set

South Tyneside District General Hospital, South Shields, Not set

Basingstoke and North Hampshire Hospital, Southampton, Not set

Southampton General Hospital, Southampton, Not set

St Richards Hospital, Southampton, Not set

Glan Clwyd Hospital, St Asaph, Not set

Stafford District General Hospital, Stafford, Not set

Lister Hospital, Stevenage, Not set

Sunderland Royal Hospital, Sunderland, Not set

Great Western Hospital, Swindon, Not set

Torbay District General Hospital, Torquay, Not set

Royal Cornwall Hospital, Truro, Not set

Hillingdon Hospital, Uxbridge, Not set

Pinderfields General Hospital, Wakefield, Not set

West Herts, Watford, Not set

Arrowe Park Hospital, Wirral, Not set

Worcestershire Acute Hospitals NHS Trust, Worcester, Not set

Worthing Hospital, Worthing, Not set

York District Hospital, York, Not set

Conditions: Follicular Lymphoma

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A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation

NCT06045806

Active Not Recruiting

The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/09/2025

Locations: Local Institution - 0131, Los Angeles, California +100 locations

Local Institution - 0131, Los Angeles, California

Local Institution - 0126, Orange, California

Local Institution - 0113, Sacramento, California

Colorado Blood Cancer Institute, Denver, Colorado

Yale University School of Medicine, New Haven, Connecticut

AdventHealth Orlando, Orlando, Florida

Local Institution - 0121, Atlanta, Georgia

Local Institution - 0104, Atlanta, Georgia

Local Institution - 0151, Boston, Massachusetts

Ascension Providence Hospital, Southfield, Michigan

M Health Fairview Clinics and Surgery Center, Minneapolis, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Columbia University Irving Medical Center, New York, New York

Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Local Institution - 0132, Philadelphia, Pennsylvania

Local Institution - 0124, Austin, Texas

Local Institution - 0109, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 0007, Camperdown, New South Wales

Local Institution - 0005, Brisbane, Queensland

Local Institution - 0004, Melbourne, Victoria

Local Institution - 0006, Melbourne, Victoria

Local Institution - 0008, Melbourne, Victoria

Local Institution - 0011, Murdoch, Western Australia

Local Institution - 0089, Salzburg, Not set

Local Institution - 0090, Wien, Not set

Local Institution - 0083, Anderlecht, Bruxelles-Capitale, Région De

Local Institution - 0084, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0144, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0133, Edmonton, Alberta

Local Institution - 0001, Hamilton, Ontario

Local Institution - 0134, Montreal, Quebec

Local Institution - 0070, Odense, Syddanmark

Local Institution - 0047, Pessac, Aquitaine

Institut Paoli-Calmettes, Marseille, Bouches-du-Rhône

Hopital Claude Huriez - CHU de Lille, Lille, Nord

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Pays-de-la-Loire

Local Institution - 0046, Pierre-Bénite, Rhône

Henri Mondor Hospital, Créteil, Val-de-Marne

Local Institution - 0028, Villejuif, Val-de-Marne

Local Institution - 0029, Poitiers, Vienne

Local Institution - 0082, Paris, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Local Institution - 0031, Paris, Île-de-France

Local Institution - 0072, Heidelberg, Baden-Württemberg

Local Institution - 0078, Ulm, Baden-Württemberg

Local Institution - 0077, Nuremberg, Bayern

Local Institution - 0073, Köln, Nordrhein-Westfalen

Local Institution - 0087, Leipzig, Sachsen

Local Institution - 0079, Dresden, Not set

Local Institution - 0115, Essen, Not set

Local Institution - 0076, Hamburg, Not set

Local Institution - 0074, Wuerzburg, Not set

Local Institution - 0063, Patras, Achaḯa

Local Institution - 0061, Athens, Attikí

Local Institution - 0062, Chaidari, Attikí

Local Institution - 0060, Thessaloniki, Thessaloníki

Local Institution - 0055, Be'er Sheva, HaDarom

Local Institution - 0058, Petah-Tikva, HaMerkaz

Local Institution - 0057, Ramat Gan, HaMerkaz

Local Institution - 0088, Tel Aviv, Tell Abīb

Local Institution - 0056, Haifa, Not set

Local Institution - 0059, Jerusalem, Not set

Local Institution - 0064, Rozzano, Milano

Local Institution - 0065, Bologna, Not set

Local Institution - 0066, Roma, Not set

Nagoya City University Hospital, Nagoya, Aichi

Hokkaido University Hospital, Sapporo, Hokkaido

Hyogo Medical University Hospital, Nishinomiya, Hyogo

Kanazawa University Hospital, Kanazawa, Ishikawa

Local Institution - 0085, Isehara, Kanagawa

Japanese Red Cross Medical Center, Shibuya-ku, Tokyo

Chiba University Hospital, Chiba, Not set

Kyushu University Hospital, Fukuoka, Not set

Okayama University Hospital, Okayama, Not set

Local Institution - 0071, Shimotsuke, Not set

Chonnam National University Hwasun Hospital, Hwasun, Jeonranamdo

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Local Institution - 0038, Seoul, Seoul Teugbyeolsi

Local Institution - 0043, Seoul, Seoul Teugbyeolsi

Asan Medical Center, Seoul, Seoul-teukbyeolsi

Local Institution - 0069, Oslo, Not set

Local Institution - 0027, Lublin, Lubelskie

Local Institution - 0095, Warsaw, Mazowieckie

Local Institution - 0023, Warsaw, Mazowieckie

Local Institution - 0026, Gdańsk, Not set

Local Institution - 0024, Poznań, Not set

Local Institution - 0022, Gliwice, Śląskie

Local Institution - 0091, Bucharest, Not set

Local Institution - 0020, Badalona, Barcelona [Barcelona]

Local Institution - 0017, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Local Institution - 0012, Pamplona, Navarra

Local Institution - 0021, Madrid, Not set

Local Institution - 0013, Salamanca, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Local Institution - 0093, Birmingham, England

Local Institution - 0080, London, London, City Of

Local Institution - 0094, London, London, City Of

Conditions: Multiple Myeloma

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CARPALL: Immunotherapy with CD19+CD22 CAR T-cells for CD19+ and CD22+ Acute Lymphoblastic Leukaemia

NCT02443831

Recruiting

This study aims to evaluate the safety, efficacy and duration of response of CD19+CD22 Chimeric Antigen Receptor (CAR) redirected autologous T-cells in children with high risk, relapsed CD19+ and CD22+ acute lymphoblastic leukaemia

Gender:

ALL

Ages:

24 years and below

Trial Updated:

03/26/2025

Locations: Great Ormond Street Hospital, London, Not set +2 locations

Conditions: Acute Lymphoblastic Leukemia

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Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

NCT01085617

Completed

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. It is not yet known which r... Read More

Gender:

ALL

Ages:

Between 25 years and 65 years

Trial Updated:

03/25/2025

Locations: UCL Cancer Institute, London, England

Conditions: Leukemia, Mucositis, Oral Complications

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