Utah is currently home to 1221 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Salt Lake City, Murray, Ogden and West Jordan. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort
NCT05295277
Recruiting
The purpose of this research use only (RUO) study is to detect genomic structural variants (SVs) in human DNA by Optical Genome Mapping (OGM) using the Bionano Genomics Saphyr system. SVs are a type of genetic alternation that includes deletions, duplications, and both balanced and unbalanced rearrangements (ex: inversions or translocations), as well as specific repeat expansions and contractions. The results of OGM analysis will be compared to prior clinical genetic test results to determine ho... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/04/2023
Locations: Lineagen (A Bionano Genomics Company), Salt Lake City, Utah
Conditions: Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly, Fragile X Syndrome, Facioscapulohumeral Muscular Dystrophy 1
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A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03988439
Recruiting
This study is to evaluate the safety, the systemic exposure, and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-118 lotion in pediatric participants with moderate to severe plaque psoriasis.
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
07/25/2023
Locations: Bausch Site 4, Murray, Utah
Conditions: Psoriasis
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Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain
NCT04902339
Recruiting
The primary aim of this pilot trial is to enhance the efficacy of the Mindfulness-Oriented Recovery Enhancement (MORE) intervention by adding neurofeedback (NF) of the Orbitofrontal Cortex (OFC) as an adjunct to the savoring component of MORE. We hypothesize that the use of NF to train OFC responses during savoring will amplify patients' ability to savor and thereby increase brain responsivity to natural rewards; such enhanced reward responding will in turn be associated with improvements in cli... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2023
Locations: Center on Mindfulness and Integrative Health Intervention Development, Salt Lake City, Utah
Conditions: Chronic Pain Syndrome, Opioid Use
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Ketamine Assisted Psychotherapy for Opioid Use Disorder
NCT04892251
Recruiting
This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2023
Locations: Center on Mindfulness and Integrative Health Intervention Development, Salt Lake City, Utah
Conditions: Opioid-use Disorder
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Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence (TEACH)
NCT05141396
Recruiting
The purpose of this trial is to evaluate if augmenting a usual audit and feedback implementation approach with telehealth-enabled support improves coordinated spontaneous awakening/breathing trials and patient outcomes for mechanically ventilated patients.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
06/29/2023
Locations: American Fork Hospital, American Fork, Utah
Conditions: Respiration, Artificial
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Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
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A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers
NCT05917015
Recruiting
This study is designed to determine if a dieatary supplement containing beta-glucan can reduce the incidence, severity and duration of upper respiratory tract infections among a group of highly trained athletes
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
06/14/2023
Locations: US Ski and Snowboard Center of Excellence, Park City, Utah
Conditions: Upper Respiratory Tract Infections, Mental Stress
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Heart Rate Variability Biofeedback Following Traumatic Brain Injury
NCT05913505
Recruiting
Individuals with mild traumatic brain injury will be randomly assigned to an active heart rate variability biofeedback condition and a sham condition. The investigators will use a randomized pre-post design that will consist of two data collection phases and a 5-week treatment condition. The heart rate variability biofeedback active condition is designed to increase heart rate oscillations (Osc+ condition) consistent with current best practices, while the sham control heart rate variability biof... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/12/2023
Locations: Brigham Young University, Provo, Utah
Conditions: Traumatic Brain Injury
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Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT01060371
Recruiting
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as Machado-Joseph disease and SCA 6). The diseases are rare, slowly progressive, cause increasingly severe neurological difficulties and are variable across and within genotypes. The purpose of this research study is to bring together a group of experts... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
05/30/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
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NETs: Protection or Harm in Neonatal Inflammation or Infection
NCT00747851
Recruiting
This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams) and PMNs from cord blood of healthy term infants will be isolated and stimulated with PAF, a biologically active phospholipid implicated in the pathogenesis of NEC. NEC, a disease of prematurity with an incidence of 10.1% of infants born weighing between 501 - 1500 grams... Read More
Gender:
ALL
Ages:
1 hour and below
Trial Updated:
05/05/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Necrotizing Enterocolitis (NEC)
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Stroke Rehabilitation, Functional Recovery, and Cost-effectiveness
NCT04279977
Recruiting
The investigators will determine the client and non-client variables associated with discharge to an inpatient rehabilitation facility vs. skilled nursing facility in individuals' post-stroke. The investigators will determine how these variables are associated with short-term (discharge from facility) and long-term (6-months post-stroke) function and quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Stroke
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JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT05490472
Recruiting
This study is to evaluate the safety and tolerability of JAB-2485 monotherapy in adult participants with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2023
Locations: University of Utah Huntsman Cancer Institute, Salt Lake City, Utah
Conditions: Solid Tumors, ER+ Breast Cancer, Triple Negative Breast Cancer, TNBC, ARID1A Gene Mutation, Small Cell Lung Cancer, SCLC
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