Utah is currently home to 1240 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Salt Lake City, Murray, Ogden and West Jordan. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Natural History, Diagnosis, and Outcomes for Leukodystrophies
Recruiting
The goals of this protocol is to diagnose, care for, and understand the clinical histories and outcomes of people with leukodystrophies.
Gender:
All
Ages:
All
Trial Updated:
11/24/2023
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Leukodystrophy
The Efficacy of the 2023-2024 Updated COVID-19 Vaccines Against COVID-19 Infection
Recruiting
The purpose of this research study is to find out how well two different 2023-2024 updated COVID-19 vaccines protect people from COVID-19 (the disease caused by the SARS-CoV-2 virus), and to determine if getting a 2023-2024 updated vaccine provides better protection from COVID-19 than not getting a vaccine. If the participant chooses to get a 2023-2024 updated COVID-19 vaccine as part of this study, they will have a 50/50 chance of receiving either the Novavax or Pfizer mRNA vaccine. If the pa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/22/2023
Locations: University of Utah School of Medicine, Salt Lake City, Utah
Conditions: COVID-19, Vaccine-Preventable Diseases, SARS CoV 2 Infection, Upper Respiratory Tract Infection, Upper Respiratory Disease
Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)
Recruiting
The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/22/2023
Locations: Clinical Study Site, Salt Lake City, Utah
Conditions: Lupus Nephritis, Immunoglobulin A Nephropathy
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Recruiting
This Phase 3 study is a randomized, double-blind, vehicle-controlled, multiple-center, parallel study to evaluate efficacy and safety of ENERGI-F703 GEL compared with vehicle control in subjects with Wagner Grade 1 to Grade 2 diabetic foot ulcers. Baseline target ulcer size (<16 cm2 vs ≥16 cm2 ) will be included as a stratification factor. Subjects will be randomized 1:1 to receive ENERGI-F703 GEL or vehicle control using an interactive web response system for randomization to automatically assi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Wasatch Clinical Research, Salt Lake City, Utah
Conditions: Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers
Recruiting
This is a Phase II, open-label, 2-arm, multicenter, international study designed to evaluate the efficacy of zenocutuzumab alone or in combination in patients with the following diagnoses: Group A: NRG1+ NSCLC Group B: mCRPC
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Utah Cancer Specialists, Salt Lake City, Utah
Conditions: NSCLC Harboring NRG1 Fusion, Metastatic Castration-resistant Prostate Cancer
MElanoma Research Lymph Node Prediction Implementation National_001
Recruiting
MERLIN_001 is a prospective registry study of a primary melanoma gene-signature to predict sentinel node (SN) status and to determine its prognostic value for more accurate staging of SN-negative melanoma patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Huntsman Cancer Institute, Salt Lake City, Utah
Conditions: Melanoma
CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes
Recruiting
This is a multicenter, cross-sectional, cohort study which will collect contemporary sweat chloride (SC) values from approximately 5000 Cystic Fibrosis (CF) patients prescribed and currently receiving commercially approved Cystic Fibrosis transmembrane conductance regulator (CFTR) modulator therapies.
Gender:
All
Ages:
4 months and above
Trial Updated:
11/21/2023
Locations: Primary Children's Cystic Fibrosis Center, Salt Lake City, Utah
Conditions: Cystic Fibrosis
RiLuzole to Reduce Atrial FIb Study Using Holter Monitoring
Recruiting
Atrial fibrillation (AF) is a growing clinical problem.1 AF is a highly dynamic condition involving episodes of sinus rhythm interspersed with periods of arrhythmia, becoming more difficult to terminate over time. AF carries a substantial cost, morbidity and mortality burden. There are two important approaches to the management of AF: 1). Controlling ventricular response rate without attempting to terminate or prevent AF (rate control), and 2). Attempting to control and maintain sinus rhythm (rh... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Atrial Fibrillation Paroxysmal
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
Recruiting
First, the investigators plan to use a retrospective analysis to determine the clinical landscape of neurofibromatosis (NF)1-associated malignant peripheral nerve sheath tumor (MPNST) and precursor lesions (e.g., atypical or nodular plexiform neurofibromas). A worldwide database will be established, collecting, in a standardized manner, histologic, immunohistochemical, molecular, radiographic, treatment, and related clinical data from centers worldwide with expertise in these NF1-related cancers... Read More
Gender:
All
Ages:
All
Trial Updated:
11/20/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Malignant Peripheral Nerve Sheath Tumors
Impact of Non-Exudative Type 1 MNV on AMD Progression
Recruiting
The overall goal of the proposed research project is to provide evidence that a specific subtype of neovascularization that may develop in eyes with age-related macular degeneration (AMD) prevents vision loss. This concept challenges the current view that the development of neovascularizations in AMD represents a harmful event in general. Notably, before the era of anti-vascular endothelial growths factor (VEGF) therapy, destruction and surgical removal of neovascular membranes have been tested... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
11/15/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Age-Related Macular Degeneration, Neovascularization, Choroidal
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body
Recruiting
This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy x-rays, gamma rays, or protons to kill tumor cells and shrink tumors. Drugs used in usual chemotherapy, such as leucovorin, 5-fluorouracil, oxaliplatin, and capecitabine, wor... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Farmington Health Center, Farmington, Utah
Conditions: Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Metastatic Esophageal Adenocarcinoma, Metastatic Gastric Adenocarcinoma, Oligometastatic Esophageal Adenocarcinoma, Oligometastatic Gastric Adenocarcinoma, Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IV Gastric Cancer AJCC v8, Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering
Recruiting
Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT is to control curve progression by applying compression on the convex side of the spine deformity. While there has been great initial enthusiasm about the technique as an alternate treatment option to spinal fusion for skeletally immature children with scoliosis, there is a need to better understan... Read More
Gender:
All
Ages:
18 years and below
Trial Updated:
11/14/2023
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Scoliosis Idiopathic