There are currently 311 clinical trials in Norfolk, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital of the King's Daughters, Virginia Oncology Associates, Sentara Norfolk General Hospital and Eastern Virginia Medical School. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
NCT06346600
Recruiting
This is a Prospective, Non-interventional, Multicenter, Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD). All subject who completed the parent clinical study (NCT06213038 and NCT05986864) will undergo safety and efficacy assessments up to 5 years post study drug injection.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/03/2024
Locations: Wagner Macula & Retina Center, Norfolk, Virginia
Conditions: Neovascular (Wet) Age-related Macular Degeneration
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Ordered Eating and Acute Exercise
NCT06242015
Recruiting
There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of glucose-hyperglycemia-is a defining characteristic and risk factor for type 2 diabetes mellitus. Consuming a carbohydrate-rich food as the final food in a meal sequence has been shown to significantly reduce postprandial glucose excursions in both diabetes patients and in... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/01/2024
Locations: ODU Human Performance Laboratory, Norfolk, Virginia
Conditions: Glucose Metabolism Disorders, Hunger
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A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium
NCT05456425
Recruiting
The objective is to evaluate the safety and efficacy of low dose and high dose CBT-001 eye drop dosed twice daily for 24 months compared to vehicle in reducing conjunctival hyperemia and preventing pterygium progression in eyes with pterygia.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/29/2024
Locations: Wagner Macula & Retina Center, Norfolk, Virginia
Conditions: Pterygium
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Study of AC699 in Patients With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Locally Advanced or Metastatic Breast Cancer
NCT05654532
Recruiting
This clinical trial is evaluating a drug called AC699 in participants with estrogen receptor positive/human epidermal growth factor 2 negative (ER+/HER2-) locally advanced or metastatic breast cancer. The main goals of this study are to: * Identify the recommended dose of AC699 that can be given safely to participants * Evaluate the safety profile of AC699 * Evaluate the pharmacokinetics of AC699 * Evaluate the effectiveness of AC699
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Site 05, Norfolk, Virginia
Conditions: Breast Cancer
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Subscapularis Repair in Reverse Shoulder Arthroplasty
NCT05438914
Recruiting
This study will evaluate the subscapularis repair versus non-repair during a reverse shoulder arthroplasty (RSA).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/29/2024
Locations: Jordan Young Institute, Norfolk, Virginia
Conditions: Rotator Cuff Tear Arthropathy
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Digestive & Liver Disease Specialists, Norfolk, Virginia
Conditions: NASH - Nonalcoholic Steatohepatitis
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Use of Harmonic Scalpel to Decrease Lymphatic and Chest Tube Drainage After Lymph Node Dissection With Lobectomy.
NCT00591552
Recruiting
In an effort to elucidate whether the Harmonic Scalpel will improve sealing lymphatics and decrease lymphatic drainage thereby decreasing the length of time that chest tubes are required and minimizing length of stay; the Harmonic Scalpel will be compared to a control group which uses electrocautery. This study will assess these two different methods to determine if there is a notable decrease in the amount of drainage with one versus the other.
Gender:
ALL
Ages:
Between 20 years and 75 years
Trial Updated:
11/20/2023
Locations: Sentara Norfolk General Hospital/Sentara Heart Hospital, Norfolk, Virginia
Conditions: Lung Cancer
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Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT
NCT04858776
Recruiting
This is a study of a medical procedure that utilizes a commercially available catheter (the Bullfrog® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate injection) around the deep veins after DVT recanalization, where DVT symptoms were present for at least 14 days and no more than 60 days prior to recanalization. The goal of the study is to see if local anti-inflammation helps prevent re-thrombosis of the blood vessel and imp... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
10/17/2023
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Iliofemoral; Thrombosis
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Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies
NCT04311073
Recruiting
This is a Double-blinded randomized placebo-controlled trial based at Eastern Virginia Medical School. Subjects who are identified in clinic having menorrhagia or abnormal Uterine bleeding (AUB) due to uterine fibroids and meet inclusion criteria based on the ultrasound (US) or Magnetic Resonance Imaging (MRI), aged 18-45 undergoing laparoscopic or Robotic assisted myomectomies. A total of 50 women in each arm of the study with symptomatic fibroids. Patients will be randomized to receive a singl... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
09/07/2023
Locations: EasternVMC, Norfolk, Virginia
Conditions: Fibroid Uterus, Abnormal Uterine Bleeding, Myoma;Uterus
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A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception
NCT04143659
Recruiting
This is a Phase I multicenter, open-label, dose-ranging, three-dose PK and PD study of injectable LB administered as an IM or SQ injection at 40 mg, and subsequently at 50mg SQ and then 60 mg SQ depending on the preliminary pharmacokinetic and pharmacodynamic results obtained with 40 mg dosing.
Gender:
FEMALE
Ages:
Between 18 years and 40 years
Trial Updated:
08/11/2023
Locations: Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Healthy Women, Female Contraception
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Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: Sentara Heart Hospital, Norfolk, Virginia
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
Register for Updates