Washington is currently home to 1725 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Seattle, Spokane, Tacoma and Vancouver. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effectiveness of Remote Foot Temperature Monitoring
NCT05728411
Recruiting
Diabetic foot ulcers are common, debilitating, and costly complications of diabetes, disproportionately impacting Black and rural Veterans. Forty percent of individuals have an ulcer recurrence within a year of ulcer healing and 65% within 5 years. Monitoring plantar foot temperatures is one of the few interventions that reduces the risk of ulcer recurrence. Despite the evidence, adoption has been poor because the original procedures, including the use of handheld thermometers, were burdensome a... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
09/11/2024
Locations: VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington
Conditions: Diabetic Foot
Register for Updates
Pilot Trial of the RUBI Program for Autistic Adults
NCT06593613
Recruiting
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI intervention feasible and acceptable for autistic adults and their families? * Does the redesigned RUBI intervention reduce challenging behaviors and enhance the quality of life for autistic adults? * Rese... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Seattle Children's Autism Center, Seattle, Washington
Conditions: Autism Spectrum Disorder, Behavior, Parenting
Register for Updates
Neoadjuvant INBRX-106 (Hexavalent OX40 Agonist) in Combination With Pembrolizumab as a Chemotherapy-sparing Regimen for Stage II TNBC (Triple Negative Breast Cancer) Patients
NCT06353997
Recruiting
This is a Phase II trial to assess feasibility of pembrolizumab + INBRX-106 as a chemotherapy-sparing neoadjuvant therapy. One therapeutic arm is being evaluated to provide an informal comparison of pharmacodynamic and clinical effects of concurrent dosing schedule.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Swedish Cancer Institute, Seattle, Washington
Conditions: Triple Negative Breast Cancer
Register for Updates
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
NCT06005194
Recruiting
The purpose of this randomized controlled trial is to evaluate whether the InMotion intervention, delivered via telehealth (using a HIPAA-compliant video platform or phone), which uses evidence-based behavioral and motivational counseling to increase daily physical activity, is an effective treatment for Major Depressive Disorder (MDD) for people who are at least one year out from sustaining a traumatic brain injury (TBI). The first aim is to compare the efficacy of the InMotion intervention to... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
09/09/2024
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: TBI (Traumatic Brain Injury), Depressive Disorder, Major, Clinical Depression, Mood Depressed, Physical Inactivity
Register for Updates
Glaucoma Evaluation With the P200TE
NCT06305481
Recruiting
Images captured on the P200TE device on glaucoma patients
Gender:
ALL
Ages:
22 years and above
Trial Updated:
09/05/2024
Locations: Specialty Eyecare Centre, Bellevue, Washington
Conditions: Glaucoma
Register for Updates
Transcutaneous Stimulation for Neurological Populations
NCT04467437
Recruiting
The purpose of the study is to evaluate whether non-invasive stimulation over the spinal cord at the neck and/or lower back can improve walking function for people with neurologic conditions. Spinal stimulation has been used extensively for individuals with spinal cord injury, and has demonstrated improvements in function. This study will extend this work to other neurologic conditions, such as cerebral palsy and stroke, that also demonstrate similar impairments as spinal cord injury. The prima... Read More
Gender:
ALL
Ages:
Between 4 years and 70 years
Trial Updated:
09/05/2024
Locations: University of Washington, Seattle, Washington
Conditions: Neurological Disorder, Cerebral Palsy
Register for Updates
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis
NCT04370301
Recruiting
This initial cohort of this phase II trial studied the outcomes of using a JAK inhibitor prior to reduced intensity haploidentical (Haplo) transplantation for the treatment of primary or secondary myelofibrosis (MF). The primary risk of using Haplo HCT in patients with MF is graft failure. In the first cohort, all patients engrafted. There were no instances of graft failure. However, a large number of patients did have graft versus host disease as a complication of their transplant. JAK inhibito... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington
Conditions: Primary Myelofibrosis, Secondary Myelofibrosis
Register for Updates
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
ALL
Ages:
All
Trial Updated:
09/03/2024
Locations: Seattle Children's Hospital and Regional Medical Center, Seattle, Washington
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
Register for Updates
Neuroblastoma Biology Study
NCT01587300
Recruiting
Medical scientists want to find better ways to treat neuroblastoma and to find ways to prevent the tumor from growing back. To do this, they need more information about the characteristics of neuroblastoma cells. Therefore, they want to study samples of neuroblastoma tissues and neuroblastoma and normal cells in the blood and bone marrow that may be related to the growth of neuroblastoma cells. Doctors and other medical scientists also want to find better ways to detect and measure neuroblastoma... Read More
Gender:
ALL
Ages:
Between 31 days and 99 years
Trial Updated:
09/01/2024
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Neuroblastoma
Register for Updates
Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial
NCT06565416
Recruiting
The present study seeks to examine the implementation process of culturally tailoring screening and brief intervention for both chronic pain and opioid misuse/opioid use disorder in three American Indian and Alaska Native (AI/AN) serving clinics. The investigators also will assess staff perspectives on this implementation as well as a survey to understand clients at these sites who have chronic pain and opioid misuse/opioid use disorder.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/30/2024
Locations: Clinic Site B (blinded pending tribal approval), Toppenish, Washington
Conditions: Opioid Use Disorder, Opioid Misuse, Chronic Pain
Register for Updates
Real-world Experiences of Alcohol and Cognitions Over Time
NCT06579521
Recruiting
The goal of this clinical trial is to examine how alcohol affects young adults' attention in both laboratory and real-world settings through phone-based cognitive tasks. The main questions this trial is designed to answer are: * How well do the phone-based cognitive tasks capture alcohol's effects on attention? * Does the effect of alcohol on attention contribute to risk-taking? Participants will complete cognitive tasks to assess attention before and after consuming a standard amount of alcoh... Read More
Gender:
ALL
Ages:
Between 21 years and 25 years
Trial Updated:
08/27/2024
Locations: University of Washington, Seattle, Washington
Conditions: Alcohol Intoxication
Register for Updates
MDMA-Assisted Therapy for Pathological Narcissism
NCT06565494
Recruiting
This open-label, proof-of-concept pilot study will assess the efficacy and safety of midomafetamine (MDMA) - assisted therapy (AT) for participants diagnosed with pathological narcissism. As all participants will be allocated to a single group assignment, there will be no blinding, randomization, or comparator treatment. Participants will have a screening visit, a preparation period of 3 visits, a treatment period receiving MDMA-AT at 3 monthly visits, a 6 month follow up period coming in at one... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/26/2024
Locations: University of Washington, Seattle, Washington
Conditions: Narcissism
Register for Updates