Washington is currently home to 1725 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Seattle, Spokane, Tacoma and Vancouver. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness
Recruiting
PROMISE aims to create a comprehensive nationwide registry of prostate cancer patients with germline pathogenic variants by prospectively screening approximately 5,000 subjects with a confirmed prostate cancer diagnosis, either through tissue biopsy, PSA greater than 100 ng/dL and/or radiographic evidence of disease and receiving systemic therapy for prostate cancer. Patients at all stages of disease will be welcome to participate in the PROMISE Registry. Participants will be recruited \& scree... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Prostate Cancer
Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Recruiting
Stuttering negatively impacts communication and reduces the overall quality of life and well-being of individuals who stutter. This study will provide a strong foundation for developing neural and behavioral interventions for stuttering. Participants will be asked to name pictures, read words/sentences silently or aloud, and listen to speech and nonspeech sounds while their speech, muscle, and brain signals are collected. Some participants may also receive brain stimulation while reading and spe... Read More
Gender:
ALL
Ages:
3 years and above
Trial Updated:
08/02/2024
Locations: Univeristy of Washington, Seattle, Washington
Conditions: Healthy Subjects, Stuttering, Developmental
Drug Excretion in Breast Milk
Recruiting
This is a prospective, non-randomized, phase I study design evaluating the in vivo activities and expression of OCT1 and BCRP in mammary gland of lactating women at three time points postpartum.
Gender:
ALL
Ages:
Between 14 days and 50 years
Trial Updated:
08/02/2024
Locations: University of Washington, Seattle, Washington
Conditions: Lactation, Postpartum, Drugs in Breast Milk, Mammary Drug Transporters, BCRP, OCT1
Non-Surgical Management of Knee Osteoarthritis in the Military Health System (MHS)
Recruiting
This study will compare two different treatment approaches for the management of knee osteoarthritis (OA). All subjects will receive a standardized approach consistent with the core set of recommendation from the Department of Defense (DoD) and Veterans Administration (VA) Clinical Practice Guidelines for Non-Surgical Management of Knee Osteoarthritis. Follow-up will occur over a 1 year period.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/30/2024
Locations: Madigan Army Medical Center, Tacoma, Washington
Conditions: Knee Osteoarthritis
A Crowd Sourcing Platform for Patients With Cancer
Recruiting
All4Cure aims to accelerate learning about cancer by sharing medical information and research results from cancer patients with fellow cancer patients, oncologists, and scientists on the All4Cure website with the hope that together patients, clinicians and researchers can cure cancer faster.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: All4Cure, Seattle, Washington
Conditions: Cancer
CHronic Nonbacterial Osteomyelitis International Registry
Recruiting
The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
07/27/2024
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*
Recruiting
To compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.
Gender:
ALL
Ages:
Between 6 years and 18 years
Trial Updated:
07/23/2024
Locations: Shriners Children's Spokane, Spokane, Washington
Conditions: Idiopathic Toe Walking
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Swedish Cancer Institute, Seattle, Washington
Conditions: Diffuse Large B-cell Lymphoma
Effective Caregiving for Neonatal Abstinence Syndrome: Testing an Instructional Mobile Technology Platform for High-Risk Pregnant Women
Recruiting
Most newborns experiencing Neonatal Abstinence Syndrome (NAS) require non-pharmacologic care, which entails, most importantly, maternal involvement with her newborn. To facilitate positive maternal-newborn interactions, mothers need to learn effective caregiving NAS strategies while they are pregnant, yet, an enormous gap exists in the early education of mothers on the symptoms and progression of NAS, in part because no interventions exist to prepare future mothers for the challenges of caring f... Read More
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
07/22/2024
Locations: Washington State University, Spokane, Washington
Conditions: Neonatal Abstinence Syndrome, Opioid-use Disorder
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
Recruiting
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure and heart rate, time to onset and to maximal response, and the duration of response; to assess the safety of the product in this population; and to character... Read More
Gender:
ALL
Ages:
Between 12 years and 16 years
Trial Updated:
07/22/2024
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Hypotension
MYLUNG Consortium Part 3: Observational Study
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Northwest Cancer Specialists, P.C., Vancouver, Washington
Conditions: Carcinoma, Non-Small-Cell Lung
Improving Surgical Outcomes With Early PT After ACDF
Recruiting
The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving outcomes after hospital discharge for ACDF surgery. The main question this clinical trial aims to answer are: * Whether early PT participants will demonstrate greater improvements in outcomes compared to delayed PT participants. * Whether improvements in handgrip strength, cervical endurance, and cervical range of motion will be associated... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/15/2024
Locations: Madigan Army Medical Center, Tacoma, Washington
Conditions: Cervical Spine Degeneration, ACDF Surgery