Washington is currently home to 1679 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Seattle, Spokane, Tacoma and Bellevue. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Investigation of Medical Management to Prevent Episodes of Diverticulitis Trial
NCT05681559
Recruiting
This is a randomized trial (n=75) of a Mediterranean style Food Pattern and versus standardized guidance on fiber intake for patients with diverticulitis to evaluate the feasibility of this dietary intervention including willingness to randomize and adherence to a Med-style dietary pattern. The investigators will employ state-of-the-art behavioral interventions in the form of electronic feedback to improve health-related behaviors and support dietary customization based on participants' budget,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Harborview Medical Center, Seattle, Washington
Conditions: Diverticulitis
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Desara ® One Single Incision Sling 522 Study
NCT04772131
Recruiting
A post-market study to compare the safety and effectiveness of the Desara® One Single Incision Sling (SIS), when compared to that of an FDA cleared transobturator sling over a period of 36 months.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Stress Urinary Incontinence
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mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation
NCT06023316
Recruiting
The purpose of this Phase I study is to conduct a pilot clinical trial using a mobile app-connected, wire-free surface electromyography (sEMG) system, called mGain, that provides biofeedback-based therapy in individuals with upper limb weakness due to neurologic injury or with upper limb amputation. Our overarching hypothesis is that the mGain wireless sEMG device and mobile therapeutic gaming environment will demonstrate improved adherence to therapy when compared to standard of care and will b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: Orthocare Innovations, LLC, Edmonds, Washington
Conditions: Upper Limb Weakness Due to Central Neurologic Injury, Upper Limb Weakness Due to Peripheral Neurologic Injury, Upper Limb Weakness Due to Nerve Reconstruction, Upper Limb Weakness Due to Tendon Transfer Surgery, Stroke, Upper Limb Amputation
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Analysis of Human Movement With Assistive Devices
NCT05729061
Recruiting
The purpose of this research is to evaluate how people move about in different settings with different assistive devices or components, and to understand how people interact with different assistive technologies. Individuals that have limb weakness, limb paralysis, limb loss, and movement disorders are often provided assistive devices such as prostheses and orthoses to assist with mobility or use assistive technologies for purposes such as to regain muscle strength or retrain movements. It is im... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
10/06/2023
Locations: Orthocare Innovations, LLC, Edmonds, Washington
Conditions: Limb Loss, Limb Weakness, Limb Paralysis, Movement Disorders
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Smart Ankle-Foot Orthosis to Improve Stroke Outcomes: Smart AFO
NCT05619484
Recruiting
The Smart Ankle-Foot Orthosis (Smart AFO) system is an investigational system that combines a diagnostic ankle-foot orthosis with a mobile application to assist clinicians in optimizing an AFO user's gait by adjusting AFO stiffness and range of motion settings, and quantifying functional walking improvements in post-stroke individuals. The purpose of the clinical testing is to evaluate the Smart AFO system with its target users: post-stroke AFO users and orthotists. This may include, but is not... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: Orthocare Innovations, LLC, Edmonds, Washington
Conditions: Stroke
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Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA)
NCT03420014
Recruiting
The present study is an open-label, randomized, controlled, two-arm multi-center study of the efficacy of L19TNF treatment in combination with doxorubicin versus doxorubicin alone in metastatic leiomyosarcoma patients.
Gender:
ALL
Ages:
Between 16 years and 100 years
Trial Updated:
10/06/2023
Locations: Seattle Cancer Care Alliance 825 Eastlake Ave. E. Seattle, WA 98109 Mail Stop CE2-128, Seattle, Washington
Conditions: Leiomyosarcoma
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LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
NCT04759664
Recruiting
The study evaluates the efficacy and safety of two strengths of LUT014 Gel topically applied once a day for 4 weeks, compared to placebo, in metastatic colorectal cancer (mCRC) patients who developed Grade 2 or non-infected Grade 3 EGFRI induced acneiform lesions
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: Providence Regional Cancer Partnership, Everett, Washington
Conditions: EGFRI Induced Acneiform Lesions
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The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
NCT06072976
Recruiting
This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
Gender:
ALL
Ages:
Between 0 days and 55 years
Trial Updated:
10/03/2023
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease, Omphalocele, Midgut Volvulus
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OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
NCT03747458
Recruiting
This is a 16-Week Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of OPN-375 186 μg Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps followed by a 12-Week Open-Label Treatment Phase. The total planned number of subjects is approximately 120 adolescents (12-17 years of age) who will be randomly assigned to receive 1 of 2 study treatments using a 2:1 ratio (OPN-375 186 μg: Placebo). For the PK sub-study, up to 14 subjec... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/22/2023
Locations: Spokane ENT, Spokane Valley, Washington
Conditions: Bilateral Nasal Polyposis
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Whole Genome Sequencing (WGS) on IVF Embryos and Individual Patients
NCT05739890
Recruiting
This research project aims to utilise recent advances in whole genome sequencing of preimplantation genetic diagnosis embryos to investigate the impact of paternal age on de novo mutation rates in IVF embryos. Embryos that are deemed unsuitable for transfer following preimplantation genetic testing for monogenic/single gene disorders (PGT-M) due to the detection of genetic abnormalities will be utilized for this study. These embryos will undergo re-biopsy, and both the biopsied samples as well a... Read More
Gender:
ALL
Ages:
Between 18 years and 48 years
Trial Updated:
09/21/2023
Locations: Poma Fertility, Kirkland, Washington
Conditions: Fertility Issues, Single-Gene Defects
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Comparison Neuromuscular Blockade Monitors
NCT05006807
Recruiting
The overall objective of this research is to evaluate different laboratory-built and commercially available sensors used to measure the effects of neuromuscular blocking drugs on neuromuscular function during surgery, by measuring evoked thumb twitch response to ulnar nerve stimulation (also known as "twitch monitoring"). The specific aim is to compare mechanomyography, which is the "gold standard" laboratory measurement to assess neuromuscular blockade, to the sensors used in commercially avail... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/18/2023
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: Neuromuscular Blockade
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Effects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A
NCT04131036
Recruiting
The investigators propose to study longitudinal joint and bone density changes in patients with severe Hemophilia A. Per current standard of care, most patients are on prophylactic FVIII replacement therapy intravenously several times weekly with a goal of keeping the trough \>1% FVIII. Recent phase 3 data suggest superior bleed protection with emicizumab prophylaxis every 1-2 weeks. It is the purpose of this study to longitudinally assess joint health and bone density over 3 years and to compar... Read More
Gender:
MALE
Ages:
16 years and above
Trial Updated:
08/31/2023
Locations: Washington Center for Bleeding Disorders at Washington Institute for Coagulation, Seattle, Washington
Conditions: Hemophilia A
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