Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary Bypass
Recruiting
This is a study to determine the safety and efficacy of liothyronine sodium/triiodothyronine (Triostat), a synthetic thyroid hormone, when given to infants with congenital heart disease during cardiopulmonary bypass surgery. Funding Source - FDA OOPD.
Gender:
All
Ages:
5 months and below
Trial Updated:
07/18/2018
Locations: Seattle Children's Hospital, Seattle, Washington
Conditions: Congenital Heart Defects
Trial Evaluating the Efficacy of Apremilast for the Treatment of Frontal Fibrosing Alopecia
Recruiting
This is open label single side study involvement 20 patient treated with Apremilast. Each enrolled patient may be evaluated at by a dermatologist using the Lichen Planopilaris Activity Index and Frontal Fibrosing Alopecia Index. Other measures include physician global assessment, dermatology quality of life and patients analogue score for pruritus. Pt will have visits at Week 0,2,4,8,12,16,20,24
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2018
Locations: Bellevue Dermatology, Bellevue, Washington
Conditions: Frontal Fibrosing Alopecia
A Registry Study of Breast Microseed Treatment
Recruiting
For women diagnosed with early stage breast cancer, lumpectomy followed by radiation is a common treatment option. Radiation treatment is typically delivered to the whole breast, five times per week, for anywhere from 3 to 8 weeks. The radiation helps kill any cancer cells that may have been left over following the surgery but causes skin burns. Many studies have demonstrated that radiation to the whole breast is not necessary, that it can be delivered to a portion of the breast where the cancer... Read More
Gender:
Female
Ages:
50 years and above
Trial Updated:
03/16/2018
Locations: Swedish Cancer Institute, Seattle, Washington
Conditions: Breast Neoplasms
Impact of Tecfidera on Gut Microbiota
Recruiting
Objectives: Dimethyl fumarate (DMF) therapy may cause a measureable change in bacterial species of the gut. The primary objectives of this study are: Determine whether a measureable change in bacterial species representation follows the institution of DMF. Determine whether a specific pattern of change in the microbiota phylotype with DMF therapy correlates to onset and severity of gastrointestinal disturbances (heartburn, nausea, flatulence, and diarrhea). Determine whether any instability of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2016
Locations: EvergreenHealth MS Center, Kirkland, Washington
Conditions: Multiple Sclerosis
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction
Recruiting
This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack in the prior 5 years, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/07/2016
Locations: Heart Clinics Northwest, Spokane, Washington
Conditions: Myocardial Infarction, Sudden Death