West Virginia is currently home to 318 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Prospective Evaluation of Xerava Prophylaxis in Hematological Malignancy Patients With Prolonged Neutropenia
NCT05537896
Recruiting
Antibacterial prophylaxis is recommended in patients at high risk of infection, specifically patients undergoing acute leukemia induction therapy or hematopoietic stem cell transplant (HSCT) who are expected to have profound neutropenia (ANC\<100 neutrophils/milliliter) for more than seven days. Xerava™ (eravacycline) has a broad spectrum of activity including many multi-drug resistant strains of bacteria. It is not an agent used for treatment of febrile neutropenia, making eravacycline a very a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Aaron Cumpston, Morgantown, West Virginia
Conditions: Hematological Malignancy, Neutropenia
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Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)
NCT06087276
Recruiting
The goal of this clinical study is to compare ulixacaltamide and placebo treatment in essential tremor. The main question it aims to answer is: • Is ulixacaltamide a safe and efficacious treatment for patients with essential tremor? Participants will be asked to participate in one of two clinical studies where they will be treated with either ulixacaltamide or placebo for a period of up to 12 weeks. After the controlled study completion, they will be eligible to participate in a long-term, ope... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/03/2024
Locations: United BioSource LLC, Morgantown, West Virginia
Conditions: Essential Tremor
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Registry of Arthrex Hand and Wrist Products
NCT05046600
Recruiting
A Multi-Center, Prospective Registry to Evaluate the Continued Safety and Effectiveness of Hand and Wrist Products
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Ulnar/Radial Collateral Ligament Reconstruction, Ligament Repair or Reconstruction, Small Bone Fragments and Arthrodesis, Scapholunate Ligament Reconstruction, Carpal Fusion (Arthrodesis) of the Hand, Digital Tendon Transfers, Carpometacarpal Joint Arthroplasty
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Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy
NCT05617807
Recruiting
Standard arthroscopy has been the gold standard for treatment of meniscus tears since the 1980's. The purpose of this study is to analyze the clinical outcomes of using the smaller diameter Nanoscope for partial menisectomy. The authors hypothesize that the Nanoscopic partial menisectomy patients will have less pain and return function faster than standard arthroscopy.
Gender:
ALL
Ages:
65 years and below
Trial Updated:
03/18/2024
Locations: Marshall Orthopaedics - Teays Valley, Scott Depot, West Virginia
Conditions: Meniscus Tear
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I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
NCT04488081
Recruiting
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: COVID-19
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Homozygous Familial Hypercholesterolemia
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Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
NCT06294314
Recruiting
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
02/27/2024
Locations: Marshall University, Huntington, West Virginia
Conditions: Anterior Cruciate Ligament Rupture
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IBS Skin Patch Test Food Allergy Study
NCT06288672
Recruiting
Participants with IBS are skin patch tested (no needles) to 80 different foods and food additives, compounded for patch testing, in search of food allergies. The testing requires 3 office visits within a 4 or 5 day period. The patches are taped to the back at Visit #. At Visit #2 48 hours later, the patches are removed from the skin and the outside border of each patch is marked with a felt tip marker. At Visit #3 (final visit) 1 or 2 days later, the patch test reading is performed by the doctor... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2024
Locations: Shepherd Allergy, Barboursville, West Virginia
Conditions: Irritable Bowel Syndrome
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Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
NCT06246526
Recruiting
This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia
Conditions: Pain, Chronic Pain, Neuropathic Pain
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LE as a Marker for Periprosthetic Joint Infection
NCT05440032
Recruiting
Testing and comparison of a novel point-of-care electrochemical assay to detect and help diagnose periprosthetic joint infection on the hip and knee to the standard of care test
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Prosthetic-joint Infection
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Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry
NCT03716193
Recruiting
This protocol will take measurements of a variety of tumors involving the skin in order to assess changes in tumor oxygen from hyperoxygenation therapy and standard cancer-directed treatments, to demonstrate the clinical feasibility of using in vivo Electron Paramagnetic Resonance (EPR) Oximetry to obtain clinically useful measurements of tumor oxygen levels from cancer patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/10/2024
Locations: Todd Tenenholz, Morgantown, West Virginia
Conditions: Skin Lesion, Skin Cancer, Skin Melanoma, Tumor Skin
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OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
NCT03747458
Recruiting
This is a 16-Week Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of OPN-375 186 μg Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps followed by a 12-Week Open-Label Treatment Phase. The total planned number of subjects is approximately 120 adolescents (12-17 years of age) who will be randomly assigned to receive 1 of 2 study treatments using a 2:1 ratio (OPN-375 186 μg: Placebo). For the PK sub-study, up to 14 subjec... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/22/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Bilateral Nasal Polyposis
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