West Virginia is currently home to 346 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Kidney Transplant Rejection
Register for Updates
Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study
NCT03901807
Recruiting
Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Septic Shock, Endotoxemia
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Appalachian Mind Health Initiative
NCT04120285
Recruiting
We propose to carry out a treatment experiment in which we evaluate the extent to which randomizing primary care clinicians have access to remote internet-based Cognitive Behavior Therapy (eCBT) in rural West Virginia (WV) and Kentucky (KY) will help improve treatment of patients with Major Depressive Disorder (MDD). WV and KY are two of the most rural states in America and mental health treatment resources are low; especially in rural parts of the state.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2023
Locations: Upper Kanawha Clinic, Cedar Grove, West Virginia
Conditions: Major Depressive Disorder
Register for Updates
An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder
NCT04157062
Recruiting
The purpose of this study is to understand the role of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing opioid and other substance use and craving and improving thinking skills.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/30/2023
Locations: West Virginia University School of Medicine, Morgantown, West Virginia
Conditions: Opioid-use Disorder, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder
Register for Updates
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
NCT04165564
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Pulmonary Disease
Register for Updates
Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities
NCT04340531
Recruiting
This phase IV trial examines the effectiveness of a multi-level smoking cessation program for high-risk women in rural communities. Cigarette smoking is a major risk factor for cervical cancer in women. Rural primary care practices and providers often lack the electronic health record support to pre-identify smokers for services, as well as lack the necessary counseling training and access to comprehensive cessation programs. Implementing evidence-based smoking cessation programs in rural Appala... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
05/10/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Tobacco-Related Carcinoma
Register for Updates
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
NCT02685605
Recruiting
INTRAGO II resembles a multicentric, prospective, randomized, 2-arm, open-label clinical phase III trial which tests if the median progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM) can be improved by the addition of intraoperative radiotherapy (IORT) to standard radiochemotherapy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/09/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Glioblastoma
Register for Updates
A Prospective Real-World Multi-Center Post-Market Observational Evaluation of Supersaturated O2 Therapy Using the TherOx® Downstream® System
NCT05156996
Recruiting
The purpose of this study is to collect real-world data on the TherOx DownStream System® to assess the effectiveness and cost- effectiveness of SSO2 Therapy, compared with PCI alone for treatment of patients with acute anterior MI.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2023
Locations: Charleston Area Medical Center, Charleston, West Virginia
Conditions: Anterior Acute Myocardial Infarction (AMI)
Register for Updates
Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
NCT05507151
Recruiting
Endoscopic weight loss procedures, also termed endoscopic sleeve gastroplasty (ESG), has been proposed as a non-surgical procedure for managing obesity and offers a standard weight loss approach. Realizing there is a knowledge gap in applying ESG to morbidly obese patients with NAFLD, the investigators propose studying the efficacy of weight control and functional outcomes of ESG. This prospective pilot study is aimed to study the safety profiles, quality of life, and changes and improvements in... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/27/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Nonalcoholic Fatty Liver Disease
Register for Updates
The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations
NCT04253899
Recruiting
Patients admitted at Marshall Health - Cabell Huntington Hospital with the diagnosis of acute perforated appendicitis or appendicular abscess larger than 3cm will be admitted and treated with percutaneous drainage and the IV antibiotics for 3 days. If the patient becomes afebrile and has a normal WBC, the patient will stay in the hospital for a single day with oral antibiotics and then will be discharged to continue oral antibiotics for seven more days. If the patient is febrile or has elevated... Read More
Gender:
All
Ages:
All
Trial Updated:
04/03/2023
Locations: Marshall University School of Medicine, Huntington, West Virginia
Conditions: Perforated Appendicitis
Register for Updates
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
NCT02781883
Recruiting
The primary objectives of this study are to assess: (1) whether the combination of BP1001 plus venetoclax plus decitabine provides greater efficacy (Complete Remission [CR], Complete Remission with incomplete hematologic recovery [CRi], Complete Remission with partial hematologic recovery [CRh], than venetoclax plus decitabine alone (by historical comparison) in participants with untreated AML that cannot or elect not to be treated with more intensive chemotherapy; (2) whether BP1001-based treat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: West Virginia University/Mary Babb Randolph Cancer Center, Morgantown, West Virginia
Conditions: Acute Myeloid Leukemia (AML)
Register for Updates
Blue Light Cystoscopy With Cysview® Registry
NCT02660645
Recruiting
Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: Charleston Area Medical Center, Charleston, West Virginia
Conditions: Bladder Cancer
Register for Updates