West Virginia is currently home to 338 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder
NCT04157062
Recruiting
The purpose of this study is to understand the role of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing opioid and other substance use and craving and improving thinking skills.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/30/2023
Locations: West Virginia University School of Medicine, Morgantown, West Virginia
Conditions: Opioid-use Disorder, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder
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Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities
NCT04340531
Recruiting
This phase IV trial examines the effectiveness of a multi-level smoking cessation program for high-risk women in rural communities. Cigarette smoking is a major risk factor for cervical cancer in women. Rural primary care practices and providers often lack the electronic health record support to pre-identify smokers for services, as well as lack the necessary counseling training and access to comprehensive cessation programs. Implementing evidence-based smoking cessation programs in rural Appala... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
05/10/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Tobacco-Related Carcinoma
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Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
NCT05507151
Recruiting
Endoscopic weight loss procedures, also termed endoscopic sleeve gastroplasty (ESG), has been proposed as a non-surgical procedure for managing obesity and offers a standard weight loss approach. Realizing there is a knowledge gap in applying ESG to morbidly obese patients with NAFLD, the investigators propose studying the efficacy of weight control and functional outcomes of ESG. This prospective pilot study is aimed to study the safety profiles, quality of life, and changes and improvements in... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/27/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Nonalcoholic Fatty Liver Disease
Register for Updates
The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations
NCT04253899
Recruiting
Patients admitted at Marshall Health - Cabell Huntington Hospital with the diagnosis of acute perforated appendicitis or appendicular abscess larger than 3cm will be admitted and treated with percutaneous drainage and the IV antibiotics for 3 days. If the patient becomes afebrile and has a normal WBC, the patient will stay in the hospital for a single day with oral antibiotics and then will be discharged to continue oral antibiotics for seven more days. If the patient is febrile or has elevated... Read More
Gender:
All
Ages:
All
Trial Updated:
04/03/2023
Locations: Marshall University School of Medicine, Huntington, West Virginia
Conditions: Perforated Appendicitis
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Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
NCT02781883
Recruiting
The primary objectives of this study are to assess: (1) whether the combination of BP1001 plus venetoclax plus decitabine provides greater efficacy (Complete Remission [CR], Complete Remission with incomplete hematologic recovery [CRi], Complete Remission with partial hematologic recovery [CRh], than venetoclax plus decitabine alone (by historical comparison) in participants with untreated AML that cannot or elect not to be treated with more intensive chemotherapy; (2) whether BP1001-based treat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: West Virginia University/Mary Babb Randolph Cancer Center, Morgantown, West Virginia
Conditions: Acute Myeloid Leukemia (AML)
Register for Updates
Blue Light Cystoscopy With Cysview® Registry
NCT02660645
Recruiting
Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: Charleston Area Medical Center, Charleston, West Virginia
Conditions: Bladder Cancer
Register for Updates
Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling
NCT03412643
Recruiting
This is a prospective, single arm, open label, multicenter interventional study designed to evaluate the efficacy of neoadjuvant chemotherapy with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determined by the Celcuity CELx HER2 Signaling Function (HSF) testing.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/03/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: HER2-negative Breast Cancer
Register for Updates
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME)
NCT05387837
Recruiting
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in subjects with Neovascular (wet) Age-Related Macular Degeneration (AMD) or subjects with Diabetic Macular Edema (DME)
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: West Virginia University Eye Institute, Morgantown, West Virginia
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Register for Updates
Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device
NCT04839705
Recruiting
A prospective, multicenter, single arm, interventional study. The target patient population for this study are adult subjects with WNBAs of the anterior and posterior intracranial circulation. The primary effectiveness outcome of the study is adequate intracranial aneurysm occlusion on the 1 year angiogram as adjudicated by a core laboratory.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Wide Neck Bifurcation Intracranial Aneurysms
Register for Updates
Pregabalin vs. Gabapentin on Reducing Opioid Usage
NCT04705480
Recruiting
This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: Charleston Area Medical Center"s Level 1 Trauma Center, Charleston, West Virginia
Conditions: Analgesics, Gabapentin, Injuries, Narcotics, Pain, Trauma
Register for Updates
Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)
NCT05137314
Recruiting
The purpose of this study is to learn about the safety and effects of PLG0206 for treating periprosthetic joint infections (PJI) in conjunction with the DAIR (debridement, antibiotics and implant retention) surgical procedure for patients with periprosthetic joint infections (PJI) after total knee arthroplasty (TKA) .
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
12/21/2022
Locations: WVU, Morgantown, West Virginia
Conditions: Joint Infection
Register for Updates
Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
NCT05422742
Recruiting
The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional profile, in comparison to a group treated with SRP only and to periodontally-healthy subjects.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2022
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Periodontitis
Register for Updates