West Virginia is currently home to 325 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Morgantown, Charleston, Huntington and Wheeling. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy
NCT05617807
Recruiting
Standard arthroscopy has been the gold standard for treatment of meniscus tears since the 1980's. The purpose of this study is to analyze the clinical outcomes of using the smaller diameter Nanoscope for partial menisectomy. The authors hypothesize that the Nanoscopic partial menisectomy patients will have less pain and return function faster than standard arthroscopy.
Gender:
ALL
Ages:
65 years and below
Trial Updated:
03/18/2024
Locations: Marshall Orthopaedics - Teays Valley, Scott Depot, West Virginia
Conditions: Meniscus Tear
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I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
NCT04488081
Recruiting
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: COVID-19
Register for Updates
LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Homozygous Familial Hypercholesterolemia
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Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
NCT06294314
Recruiting
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
02/27/2024
Locations: Marshall University, Huntington, West Virginia
Conditions: Anterior Cruciate Ligament Rupture
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IBS Skin Patch Test Food Allergy Study
NCT06288672
Recruiting
Participants with IBS are skin patch tested (no needles) to 80 different foods and food additives, compounded for patch testing, in search of food allergies. The testing requires 3 office visits within a 4 or 5 day period. The patches are taped to the back at Visit #. At Visit #2 48 hours later, the patches are removed from the skin and the outside border of each patch is marked with a felt tip marker. At Visit #3 (final visit) 1 or 2 days later, the patch test reading is performed by the doctor... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2024
Locations: Shepherd Allergy, Barboursville, West Virginia
Conditions: Irritable Bowel Syndrome
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Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
NCT06246526
Recruiting
This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia
Conditions: Pain, Chronic Pain, Neuropathic Pain
Register for Updates
LE as a Marker for Periprosthetic Joint Infection
NCT05440032
Recruiting
Testing and comparison of a novel point-of-care electrochemical assay to detect and help diagnose periprosthetic joint infection on the hip and knee to the standard of care test
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Prosthetic-joint Infection
Register for Updates
Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry
NCT03716193
Recruiting
This protocol will take measurements of a variety of tumors involving the skin in order to assess changes in tumor oxygen from hyperoxygenation therapy and standard cancer-directed treatments, to demonstrate the clinical feasibility of using in vivo Electron Paramagnetic Resonance (EPR) Oximetry to obtain clinically useful measurements of tumor oxygen levels from cancer patients.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/10/2024
Locations: Todd Tenenholz, Morgantown, West Virginia
Conditions: Skin Lesion, Skin Cancer, Skin Melanoma, Tumor Skin
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OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
NCT05405374
Recruiting
The objective of this clinical study is to compare OSTEOAMP SELECT Fibers to Infuse Bone Graft, in terms of effectiveness and safety, when used as a bone graft substitute in in skeletally mature patients qualified for 2-lumbar interbody fusion (LIF) by means of an intra-patient control model.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
08/25/2023
Locations: West Virginia University, Morgantown, West Virginia
Conditions: Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
Register for Updates
Pregabalin vs. Gabapentin on Reducing Opioid Usage
NCT04705480
Recruiting
This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: Charleston Area Medical Center"s Level 1 Trauma Center, Charleston, West Virginia
Conditions: Analgesics, Gabapentin, Injuries, Narcotics, Pain, Trauma
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Huntington, West Virginia
Conditions: Ulcerative Colitis
Register for Updates
Convalescent Plasma Collection and Treatment in Pediatrics and Adults
NCT04376034
Recruiting
This is a prospective study, involving contacting potential plasma donors and the use of their plasma to help fight off infections of those suffering from COVID19 in accordance to collection guidelines for plasma and FDA IND requirement. This study will include up to 240 participants potentially receiving convalescent plasma and up to 1000 potential donors. There are 3 basic arms to the study: mild, moderate and severe/critical severity. All 3 severity groups are eligible for enrollment, but mi... Read More
Gender:
ALL
Ages:
31 days and above
Trial Updated:
05/01/2020
Locations: WVU Medicine, Morgantown, West Virginia
Conditions: COVID19, Coronavirus Infection, Coronavirus, Virus Diseases, RNA Virus Infections
Register for Updates