There are currently 546 clinical trials in Madison, Wisconsin looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Wisconsin, University of Wisconsin Hospital and Clinics, University of Wisconsin - Madison and University of Wisconsin Carbone Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy
NCT05820711
Recruiting
The goal of this clinical research study is to evaluate the safety and tolerability of injecting certain cells that you produce in your bone marrow called mesenchymal stem cells (MSCs) into your salivary glands. Participants will have head and neck cancer that was treated with radiation therapy, and in this study will: Undergo a collection of bone marrow using a needle; Donate saliva; Undergo a salivary gland ultrasound; and, Complete questionnaires that ask about dry mouth Participants can e... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
02/21/2024
Locations: University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Conditions: Head and Neck Cancer, Xerostomia
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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
NCT04831580
Recruiting
This is a randomized controlled trial to compare survival for patients who undergi robotic assisted laparoscopy versus open radical hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: University of Wisconsin Clinical Science Center, Madison, Wisconsin
Conditions: Cervical Cancer
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A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer
NCT05154487
Recruiting
This is a 2 stage multi-center study designed to evaluate the efficacy of the combination of alpelisib and fulvestrant in patients with PIK3CA-mutated ER-positive endometrioid endometrial cancers by estimating the objective response rate (ORR). Treatment will continue until either unacceptable toxicity, progression of disease, or investigator/patient request for withdrawal.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: University of Wisconsin Clinical Science Center, Madison, Wisconsin
Conditions: Endometroid Endometrial Cancer
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Vowel Space Expansion Sensorimotor Adaptation
NCT06233513
Recruiting
The purpose of this research study is to understand how the brain processes and controls speech in healthy people. The investigators are doing this research because it will help identify the mechanisms that allow people to perceive their own speech errors and to learn new speech sounds. 117 participants will be enrolled into this part of the study and can expect to be on study between 1 day (Experiment 1) and 4 weeks (Experiment 2).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/19/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Speech
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Post Market Clinical Evaluation of Gamma 4
NCT05523635
Recruiting
This is a prospective, multi-center, non-randomized, post-market clinical investigation of the Gamma 4 System. Neither subjects nor investigators are blinded to treatment. It is anticipated that a total of 100 subjects will be enrolled at five sites. Total duration of enrollment, 12 month follow-up and analysis is expected to take approximately 30 months. The clinical investigation has been designed to follow the surgeon's standard of care for subjects treated with a cephalomedullary nail for f... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: SSM Health - Madison, Madison, Wisconsin
Conditions: Femoral Fracture
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Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
NCT05929703
Recruiting
The goal of this clinical trial is to compare the Hospital Elder Life Program (HELP) with a family-augmented version of HELP (FAM-HELP), that includes family members and care partners, for the prevention of delirium in older patients during hospital admission. The main objectives of the trial are the following: To compare the effectiveness of FAM-HELP and HELP in reducing both the incidence of delirium and its severity. To compare the effectiveness of FAM-HELP and HELP in improving patient- and... Read More
Gender:
All
Ages:
70 years and above
Trial Updated:
02/14/2024
Locations: Meriter Hospital, Madison, Wisconsin
Conditions: Delirium, Neurocognitive Disorders, Mild Cognitive Impairment, Alzheimer Disease, Aging, Family Support, Family Members, Caregiver Burden, Implementation Science, Patient Satisfaction
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TOTAL: A Multisite RCT
NCT05346575
Recruiting
Nearly 8 in 10 Veterans meet criteria for overweight/obesity. Three evidence-based treatment options are available within VA (behavioral weight management [MOVE!], obesity medications, and bariatric surgery). However, all treatments are significantly underutilized. This study will evaluate the effectiveness of a novel intervention designed to increase obesity treatment initiation and subsequently weight loss within VA. The intervention, Teaching Obesity Treatment Options to Adult Learners (TOTA... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
02/14/2024
Locations: William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison, Wisconsin
Conditions: Obesity, Overweight
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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
NCT02418442
Recruiting
Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Registry will form the basis for future CARRA studies. In particular, this observational registry will be used to answer pressing questions about therapeutics used to treat pediatric rheumatic diseases, including safety questions.
Gender:
All
Ages:
21 years and below
Trial Updated:
02/13/2024
Locations: University of Wisconsin, American Family Children's Hospital, Madison, Wisconsin
Conditions: Rheumatic Joint Disease
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Evaluating Mobility Interventions in the Real World
NCT04275973
Recruiting
This study is intended to test the comparative biomechanical benefits of different lower-limb prostheses and orthoses using data collected over extended periods of everyday life using wearable sensors. Investigator seek to improve physical health, functional activity level, independence, workforce participation, and mental health in participants with lower limb amputation and other lower-limb impairments. Investigator seek to study the similarities and differences in participants' movement using... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/13/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Lower Limb Amputation, Drop Foot
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Intervention to Improve the Delivery of Follow-up Care for Low-Risk Breast Cancer
NCT05609435
Recruiting
This study tests a novel intervention designed to optimize needed survivorship care for low-risk breast cancer survivors while reducing burdensome care with limited health benefits. This study examines whether the intervention, titled REASSURE, improves survivors' preparedness for survivorship. Up to 110 participants will be on study for up to 18 months.
Gender:
Female
Ages:
Between 18 years and 95 years
Trial Updated:
02/13/2024
Locations: UW Health Oncology Clinics, Madison, Wisconsin
Conditions: Breast Cancer
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IN.PACT™ AV Access Post-Approval Study (PAS002)
NCT04543539
Recruiting
Long-term safety will be summarized
Gender:
All
Ages:
21 years and above
Trial Updated:
02/12/2024
Locations: University of Wisconsin-Madison - Meriter Hospital, Madison, Wisconsin
Conditions: Arteriovenous Fistula, Arteriovenous Fistula Stenosis, Arteriovenous Fistula Occlusion, Fistula
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Fully Automated High-Throughput Quantitative MRI of the Liver
NCT05294471
Recruiting
The purpose of this research is to see if a new automated magnetic resonance imaging (MRI) method will be able to improve the images taken of the liver. Participants will have either known or suspected liver disease, known or suspected iron overload syndrome, or be a healthy adult. Participants will be in the research study for one day.
Gender:
All
Ages:
7 years and above
Trial Updated:
02/09/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Healthy, Iron Overload, Liver Fat
Register for Updates