There are currently 662 clinical trials in Milwaukee, Wisconsin looking for participants to engage in research studies. Trials are conducted at various facilities, including Medical College of Wisconsin, Childrens Hospital of Wisconsin, Aurora Saint Luke's Medical Center and Aurora Sinai Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
External Pharyngeal Exerciser and Dysphagia
NCT05708898
Recruiting
The goal of this a clinical trial is to test the effect of a pharyngeal exerciser in rehabilitation of pharyngeal phase of swallowing in patients with dysphagia. The main question it aims to answer is: •Does application of pharyngeal exerciser improve swallowing as evidenced by need for prescribed intervention for dysphagia (maneuvers, exercises or dietary modification to prevent aspiration). Participants will: * Perform barium swallows in lateral view fluoroscopy * Over a six-week period, pe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Dysphagia
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Circulating Tumor DNA (ctDNA) in Locally Advanced Esophageal and Gastroesophageal (GE) Junction Adenocarcinoma
NCT05067842
Recruiting
This is an observational study to determine the feasibility of assessing tumor response utilizing ctDNA in patients of locally advanced esophageal and gastroesophageal junction (LA-EA/GEJ) cancer undergoing total neoadjuvant therapy (TNT) consisting of systemic chemotherapy (modified FOLFOX or FLOT/DFOX) followed by concurrent chemoradiation \[50.4 Gray (Gy) over approximately six weeks with concurrent radio sensitizing dose of carboplatin/paclitaxel\].
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/12/2024
Locations: Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Adenocarcinoma Esophagus
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Ascension, Milwaukee, Wisconsin +1 locations
Conditions: Homozygous Familial Hypercholesterolemia
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Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome
NCT05546814
Recruiting
The purpose of this project is to determine the direct impact of sodium supplementation in preterm infants and to see the overall improvement of their growth and health status. from this study will help us develop a better treatment for in the future.
Gender:
ALL
Ages:
Between 25 weeks and 30 weeks
Trial Updated:
03/11/2024
Locations: Children's wisconsin, Milwaukee, Wisconsin
Conditions: Preterm Birth
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Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
NCT06048159
Recruiting
This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Stroke, Aphasia
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Impact of Lp299v on Vascular Function in Patients With PASC
NCT05227170
Recruiting
Emerging data show that SARS-CoV-2 infection causes gut microbiome changes strongly associated with Post-Acute Sequelae of SARS-CoV-2 (PASC). The investigators and others have established that an orally ingested probiotic (Lactobacillus plantarum 299v, Lp299v) reduces circulating levels of cell-free mitochondrial DNA (cf-mtDNA), decreases toll-like receptor 9 (TLR9) activation \[and downstream interleukin (IL-6)\], and improves micro- and macrovascular (brachial artery) endothelial dysfunction \... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/11/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: COVID-19
Register for Updates
Ischemic Conditioning Improves Walking Function Post Stroke
NCT04038697
Recruiting
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking. Ischemic Conditioning (IC) is a non-invasive, simple procedure that improves motor function, exercise performance and cardiovascular function in healthy controls, but it has never been applied to the stroke population. We postulate that IC enhances the recruitment of motoneurons and results in positive neural adaptations, improves vascular endot... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/11/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin +1 locations
Conditions: Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
Register for Updates
Vascular Aging and Lp299v Study
NCT05296395
Recruiting
Emerging data suggest the gut microbiota regulates multiple mechanisms related to vascular aging, but no intervention targeting the gut microbiota has been tested in older adults without cardiovascular risk factors or cardiovascular disease. Early human data suggest an increase in potentially pathological gut metabolites such as trimethylamine-N-oxide (TMAO) are associated with older age, increased vascular stiffness, increased oxidative stress, and reduced nitric oxide (NO) bioavailability as e... Read More
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
03/11/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Vascular Aging
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Contingency Management for Drug Use: Does Age Matter?
NCT05521854
Recruiting
The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives. This will allow us to determine if older adults with substance use disorders (SUDs) are willing to engage with app-based incentives and whether they perform similarly to their younger counterparts. Because the study will leverage data from an existing study on app-based incentives, a small add-on study is... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Aurora Behavioral Health Services, Milwaukee, Wisconsin
Conditions: Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
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Vape-Free Text-Messaging: Pilot Study
NCT05906082
Recruiting
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
Gender:
ALL
Ages:
Between 18 years and 24 years
Trial Updated:
02/23/2024
Locations: University of Wisconsin-Milwaukee, Milwaukee, Wisconsin
Conditions: E-cigarette Use
Register for Updates
Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool
NCT05049330
Recruiting
Cervical spine injuries (CSI) are serious, but rare events in children. Spinal precautions (rigid cervical collar and immobilization on a longboard) in the prehospital setting may be beneficial for children with CSI, but are poorly studied. In contrast, spinal precautions for pediatric trauma patients without CSI are common and may be associated with harm. Spinal precautions result in well-documented adverse physical and physiological sequelae. Of substantial concern is that the mere presence of... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
02/21/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Cervical Spine Injury
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A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH
NCT04764474
Recruiting
An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Froedtert-Medical College of WI, Milwaukee, Wisconsin
Conditions: Isocitrate Dehydrogenase Gene Mutation
Register for Updates