There are currently 716 clinical trials in Milwaukee, Wisconsin looking for participants to engage in research studies. Trials are conducted at various facilities, including Medical College of Wisconsin, Children's Hospital of Wisconsin, Aurora Saint Luke's Medical Center and Aurora Sinai Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Intervention to Improve Diabetes Outcomes in Older African American Women With Multi-Caregiving Burden
NCT04831697
Recruiting
This is a two arm, pilot randomized control trial (RCT) in which 60 African American women (AAW), 40-64 years of age, with HbA1c ≥8% and multi-caregiving responsibilities will be recruited from communities in Milwaukee, Wisconsin and randomized to either: 1) an individual-based, social support, health educator-facilitated intervention to address multi-caregiving responsibilities (n=30), or 2) individual-based, health educator-facilitated diabetes education and skills training and general health... Read More
Gender:
Female
Ages:
Between 40 years and 64 years
Trial Updated:
05/18/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Type 2 Diabetes
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Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency
NCT04565015
Recruiting
The purpose of this study is to evaluate the pharmacokinetics and safety of Immune Globulin Intravenous (Human) GC5107 in pediatric subjects with Primary Humoral Immunodeficiency (PHID).
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
05/15/2023
Locations: University of Wisconsin, Milwaukee, Wisconsin
Conditions: Primary Immune Deficiency
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Cardiometabolic Health in Transgender Males
NCT04977765
Recruiting
Transgender individuals are those with a gender identity opposite the sex they were assigned at birth. Approximately 1% of the population is transgender, equating to ~60,000 transgender Wisconsinites. A transgender boy or man is someone with a 46,XX karyotype and typical female genitalia but a male gender identity and desire for more male-typical gender expression. Gender-affirming testosterone (hormonal) treatment (GAHT) is the cornerstone of masculinizing therapy for transgender men and boys,... Read More
Gender:
All
Ages:
Between 12 years and 30 years
Trial Updated:
05/12/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Transgender, Transgenderism
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EMST in Patients Undergoing CRT for HNCA
NCT03916809
Recruiting
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on maintenance of safe and efficient oropharyngeal swallow function in persons with cancer of the head and neck (HNCA) undergoing treatment with radiation therapy or chemoradiotherapy (RT/CRT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Wisconsin Milwaukee, Milwaukee, Wisconsin +1 locations
Conditions: Head and Neck Neoplasms, Deglutition Disorders
Register for Updates
The Feasibility and Examination of the Effects of Floatation-based REST on a Community Sample With PTSD
NCT04368689
Recruiting
This project is being done to explore the effects floating has on individuals who have a history of trauma with stress related symptoms.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/08/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Post-Traumatic Stress Disorders
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Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water
NCT05736302
Recruiting
The purpose of this study is to validate previously developed physical function-clustered specific machine-learned accelerometer algorithms to estimate total daily energy expenditure (TDEE) in individuals with general movement and functional limitations.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Wisconsin-Milwaukee, Milwaukee, Wisconsin
Conditions: Movement Disorders, Energy Metabolism
Register for Updates
Venetoclax to Augment Epigenetic Modification and Chemotherapy
NCT05317403
Recruiting
The investigator is testing the addition of venetoclax to 5-azacitidine and vorinostat followed by standard chemotherapy to enhance treatment response in AML patients.
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
04/28/2023
Locations: Children's Wisconsin, Milwaukee, Wisconsin
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
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KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
NCT03662126
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition of MDM2 is a novel mechanism of action in MF. This study will be conducted in 2 phases. Phase 2 will determine the KRT-232 recommended dose and dosing schedule; Phase 3 will test KRT-232 vs Best Available Therapy (BAT). Patients in the Phase 3 part of the study will be randomized 2:1 to receive ei... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: Medical College of Wisconsin - Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Post-Essential Thrombocythemia MF (Post-ET-MF)
Register for Updates
A Study of DF6002 Alone and in Combination With Nivolumab
NCT04423029
Recruiting
The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab in participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2023
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Solid Tumors
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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
NCT04174157
Recruiting
Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and a selective dysfunction of motor neurons. SMA is an autosomal recessive, early childhood disease with an incidence of 1:10,000 live births. SMA is the leading cause of infant mortality due to genetic diseases. Until recently, the mainstay of treatment for these patients was supportive medical care. Howe... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Children's Hospital of Wisconsin, Milwaukee, Wisconsin
Conditions: Spinal Muscular Atrophy (SMA)
Register for Updates
Age of Blood in Sickle Cell Transfusion
NCT03704922
Recruiting
The Investigators hypothesize that older red cell units trigger phagocytosis and activation of circulating macrophages with a downstream immunomodulatory cascade and release of excess Non Transferrin Bound Iron(NTBI) that leads to increased rates of infection in adults with Sickle Cell Disease(SCD). To test this hypothesis, the study staff will perform a randomized prospective clinical trial. In aim 1, the study staff will determine the biochemical differences between ≥30 day-old versus ≤10 day... Read More
Gender:
All
Ages:
Between 16 years and 60 years
Trial Updated:
04/17/2023
Locations: Versiti Wisconsin, Milwaukee, Wisconsin
Conditions: Sickle Cell Disease
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Promoting Healing Of Nerves Through Electrical Stimulation
NCT04662320
Recruiting
This study is evaluating a new therapeutic use of electrical stimulation to promote nerve healing and improve functional recovery following surgical intervention for nerve compression. A single dose of the therapeutic stimulation is delivered as part of the surgical intervention to address compression of the ulnar nerve at the elbow.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/20/2023
Locations: Medical College of Wisconsin - Hand Center, Milwaukee, Wisconsin
Conditions: Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies
Register for Updates