Mind Body Syndrome Therapy for Chronic Pain
NCT04689646
Recruiting
The goal of this study is to determine if a mind-body intervention can help people suffering from chronic back pain. The study is a randomized, partially blinded trial examining the effectiveness of a mind body intervention in reducing disability from back pain and alleviating back pain in participants as compared to usual care and an active control (second mind body intervention). The investigators will secondarily investigate whether the intervention alleviates anxiety related to the pain and... Read More
Gender:
ALL
Ages:
Between 18 years and 67 years
Trial Updated:
08/09/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Chronic Pain, Chronic Pain Syndrome
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Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment
NCT06108089
Recruiting
Tumor hypoxia is one of the physiological factors for treatment resistance and likely contributes to poor overall survival among patients with head and neck cancer (HNC). Identifying hypoxic features of HNC may allow the personalizing treatment plan. The investigators propose multiparametric Hypoxia MR (HMR) imaging using diffusion, perfusion, and oxygenation as non-invasive, in-vivo imaging components of a hypoxia phenotype. Assessing the hypoxia phenotypes' expression will be critically import... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Head and Neck Cancer, Hypoxia, Magnetic Resonance Imaging, Cancer Neck
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Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
NCT04838678
Recruiting
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function. The study will involve measuring sympathetic nervous system activity and blood flow during common laboratory physiological stress protocols (e.g. hypoxia, exercise), and in response to infusion of drugs that cause vasodilation or vasoconstriction.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/09/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Hypertension, Obesity
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Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection
NCT06112353
Recruiting
The purpose of this research study is to see the outcome of Sugammadex versus Neostigmine with Glycopyrrolate in colorectal surgery as it relates to its effects on post-surgical time (in hours) to first bowel movement and tolerance for solid food (GI-2 recovery) following bowel resection surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: UC Irvine Medical Center, Orange, California
Conditions: Intestinal Disease
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Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention
NCT05032781
Recruiting
Ischemic stroke is the leading cause of long-term disability in the United States. Endovascular intervention with mechanical thrombectomy has become the standard of care for acute large vessel occlusion (LVO) stroke since multiple clinical trials demonstrated improved long-term clinical outcomes with treatment. However, despite high rates of successful vessel recanalization and thus reperfusion of ischemic brain tissue in current practice, many patients continue to suffer debilitating strokes an... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/09/2024
Locations: North Shore University Hospital, Manhasset, New York
Conditions: Stroke, Ischemic
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Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
NCT06195059
Recruiting
The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Heart Failure, Pulmonary Vascular Disease
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The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
NCT05067998
Recruiting
Herbal Medicine is known as the medicinal use of herbal substances as a means of treating different conditions in the human body to ensure that the body remains in optimal health and wellness. These substances are known to contain very active ingredients in it and as such is also a very potent means of managing diseases and ailments in the body. Herbal medicine has always been a standby source of getting relief from various conditions over centuries, however, it can be categorically said that t... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
08/09/2024
Locations: Health for Life Holistic Wellness Center LLC, Dover, Delaware
Conditions: Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain, Hypertension,Essential
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Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities
NCT06274359
Recruiting
While the COVID-19 pandemic has highlighted health disparities, Black children have unduly suffered and died from seasonal influenza for decades. Through sustained partnership with Black community stakeholders, novel community-engaged research methods, and an innovative intervention approach, this proposal will explore, develop, and test a Digital Storytelling intervention to reduce influenza vaccination disparities in Black children aged 6 months to 5 years. This project will advance our unders... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/09/2024
Locations: Denver Health Eastside Clinic, Denver, Colorado +1 locations
Conditions: Influenza
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Imaging SV2A in Mood Disorders
NCT02734602
Recruiting
This study is designed to examine SV2A density in MDD and PTSD as a correlate of synaptic density, and to determine whether ketamine administration will reverse the synaptic loss in vivo in human subjects. To our knowledge, this is the first human study to examine SV2A in vivo in MDD and PTSD and to use the first known drug (ketamine) that rapidly reverses synaptic loss to determine whether ketamine administration could restore some of the structural changes associated with depression and PTSD.... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/08/2024
Locations: PET Center, New Haven, Connecticut
Conditions: Major Depressive Disorder, Post-Traumatic Stress Disorder
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Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma
NCT05208307
Recruiting
This phase II trial studies the effect of belantamab mafodotin, pomalidomide, and dexamethasone in treating patents with high-risk myeloma. Belantamab mafodotin is a monoclonal antibody, called belantamab, linked to a chemotherapy drug, called mafodotin. Belantamab is a form of targeted therapy because it attaches to specific molecules on the surface of cancer cells, known as BCMA receptors, and delivers mafodotin to kill them. Chemotherapy drugs, such as pomalidomide, work in different ways to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: Emory University/Winship Cancer Institute, Atlanta, Georgia
Conditions: Plasma Cell Myeloma
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Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
NCT06295367
Recruiting
This clinical trial evaluates the effect of Cost Communication and Financial Navigation (CostCOM) intervention on adherence to care and financial burden in cancer patients. Many cancer patients experience financial hardship due to high medical out of pocket costs (OOPC), changes in employment, income and insurance. Financial hardship can lead to a delay or a stop in cancer care, and is linked to poor quality of life. Financial navigation programs, such as CostCOM, provide financial counseling, e... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/08/2024
Locations: Fairbanks Memorial Hospital, Fairbanks, Alaska +180 locations
Conditions: Malignant Solid Neoplasm
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ROCKIF Trial: Re-sensitization of Carboplatin-resistant Ovarian Cancer With Kinase Inhibition of FAK
NCT03287271
Recruiting
The purpose of the study is to investigate the combination VS-6063, carboplatin, and paclitaxel. in the treatment of patients with ovarian cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: University of California San Diego, San Diego, California
Conditions: Ovarian Cancer
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