Oregon is currently home to 1214 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Closed Loop Context Aware AID
NCT06676657
Recruiting
An artificial pancreas (AP) is a control system for automatic insulin delivery. The investigators have implemented a high blood sugar detection and dosing algorithm for use within an AP control system. If a high blood sugar pattern is detected, correction insulin will be calculated and delivered. The investigators will test how well the new algorithm manages glucose compared to the AP control system without high blood sugar detection and dosing. This type of algorithm may improve glucose control... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/08/2025
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Type 1 Diabetes
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Collaboration Oriented Approach to Controlling High Blood Pressure
NCT06124716
Recruiting
Hypertension is a significant contributor to poor cardiovascular outcomes. Self-management support tools can increase patient behaviors to improve blood pressure. The investigators created a clinical decision support app, called COACH, to integrate home blood pressure data and goals into EHR reporting and workflow with communications informed by behavioral economics principles to support shared decision-making. The study aims to measure the effectiveness of the COACH intervention in a pragmatic... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/08/2025
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Hypertension, Multiple Chronic Conditions
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Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
NCT05591027
Recruiting
This clinical trial is focused on determining whether biological signatures of target engagement by a Centella asiatica water extract product administered orally for 6 weeks can be measured in comparison to placebo. This study will also assess the safety and tolerability of the Centella asiatica water extract product.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
04/08/2025
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Mild Cognitive Impairment, Alzheimer's Disease
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The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis
NCT05564936
Recruiting
ME\&MG is a standalone software (digital solution) running on patients smartphones, connected to a web portal for physicians. It is intended to be used as an unsupervised digital self-assessment tool for the monitoring of disabilities in patients living with MG. ME\&MG contains digital active tests for the assessment of ptosis, breathing, dysarthria, upper- and lower-limb (arms and legs) weakness, treatment follow-up, and validated e-questionnaires related to daily activities, pain, fatigue, sl... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: OHSU, Portland, Oregon
Conditions: Myasthenia Gravis
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Cardiac Implantable Electronic Device (CIED) Research Study
NCT05061862
Recruiting
The study is designed to collect data on Cardiovascular Implantable Electronic Device (CIED) information, implant procedure details, and/or patient characteristics to support development of future CIED products and procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: Oregon Health & Science University Hospital, Portland, Oregon
Conditions: Arrhythmias, Cardiac, Bradycardia, Tachycardia
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Glycemic Metrics and Patterns in People With and Without Prediabetes
NCT06921902
Recruiting
The FreeStyle Libre 3 Continuous Glucose Monitoring (FSL3) System is used to characterize the glycemic profiles of people with and without a prediabetes diagnosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/04/2025
Locations: Diabetes and Obesity Care, Bend, Oregon
Conditions: Pre Diabetes
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A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)
NCT06072430
Recruiting
This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relative hypovolemia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Oregon Health & Science University (OHSU), Portland, Oregon
Conditions: Septic Shock, Sepsis, Hypovolemia
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Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
NCT05705492
Recruiting
This phase II trial tests how well olanzapine works in managing cancer cachexia in patients experiencing esophagogastric, hepatopancreaticobiliary, colorectal, or lung cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) or that has spread from where it first started (primary site) to other places in the body (metastatic) -associated appetite loss while receiving non-curative cancer therapy. Loss of appetite ("anorexia") i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: OHSU Knight Cancer Institute, Portland, Oregon
Conditions: Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma, Advanced Esophageal Carcinoma, Metastatic Esophageal Carcinoma, Locally Advanced Biliary Tract Carcinoma, Locally Advanced Colorectal Carcinoma, Locally Advanced Esophageal Carcinoma, Locally Advanced Gastric Carcinoma, Metastatic Colorectal Carcinoma (mCRC), Advanced Lung Carcinoma
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FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy
NCT05135091
Recruiting
This clinical trial is designed to test whether a single image-guided intracerebral administration of inhibitory nerve cells, called interneurons (NRTX-1001), into subjects with drug-resistant unilateral mesial temporal lobe epilepsy (MTLE), with or without mesial temporal sclerosis (MTS), is safe (frequency of adverse events) and effective (seizure frequency). NRTX-1001 comprises human interneurons that secrete a neurotransmitter, gamma-aminobutyric acid (GABA).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/03/2025
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Mesial Temporal Lobe Epilepsy
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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT05040360
Recruiting
This phase II trial studies the effect of capecitabine and temozolomide after surgery in treating patients with high-risk well-differentiated pancreatic neuroendocrine tumors. Chemotherapy drugs, such as capecitabine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving capecitabine and temozolomide after surgery could prevent or delay the return of cancer in patients wit... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Saint Charles Health System, Bend, Oregon
Conditions: Metastatic Malignant Neoplasm in the Liver, Pancreatic Neuroendocrine Tumor, Stage I Pancreatic Neuroendocrine Tumor AJCC v8, Stage II Pancreatic Neuroendocrine Tumor AJCC v8, Stage III Pancreatic Neuroendocrine Tumor AJCC v8
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Identifying and Caring for Individuals With Inherited Cancer Syndrome
NCT04494945
Recruiting
This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and ovarian cancer or Lynch syndromes) instead of only testing people whose families are known to be high risk.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Providence Portland Medical Center, Portland, Oregon
Conditions: Hereditary Neoplastic Syndrome, Lynch Syndrome, Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
NCT03723928
Recruiting
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual approach to monitoring disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Saint Alphonsus Medical Center-Baker City, Baker City, Oregon
Conditions: Anatomic Stage IV Breast Cancer AJCC v8, Estrogen Receptor Positive, HER2/Neu Negative, Progesterone Receptor Positive, Prognostic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29
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