There are currently 967 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama-Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
STROKE STAT (Stroke Severity-based Triage to Accelerate Treatment)
NCT04978480
Recruiting
Acute stroke systems of care should emulate trauma systems which deliver the full range of care to all injured patients by means of organized, coordinated efforts in defined geographic areas. Just as trauma systems have proven ability to save lives of the most severely injured patients, clinicians should have a stroke system able to provide care to patients with the most severe strokes. The most severe type of acute ischemic stroke is due to proximal large vessel occlusion (LVO). Mechanical thro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stroke
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Common Factors Group Psychotherapy for General Mental Health Concerns
NCT06614842
Recruiting
The current research will investigate the impact of general psychotherapy using common factors (i.e., techniques and communication skills that are common to all major forms of psychotherapy) to investigate whether mental health professionals can treat a variety of mental health concerns utilizing this general form of psychotherapy as opposed to specific forms of psychotherapy that may require specific trainings or education.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Major Depression, Generalized Anxiety, Stress Disorder, Post Traumatic, Stress, Mental Disorders
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Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis
NCT02038166
Recruiting
The purpose of this study is to determine if acquired (partial) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) deficiency contributes substantially to the pathogenic mechanisms underlying Chronic Rhinosinusitis (CRS), creating a localized environment that impairs mucociliary clearance (MCC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Rhinosinusitis
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The Impact of a Virtual Magic Trick Training Program
NCT05664841
Recruiting
The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism. Benefits of participating in a 6-week virtual MTTP will be evaluated using validated assessments to measure social-emotional competencies.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Autism, Pervasive Developmental Disorder
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Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
NCT04368559
Recruiting
The purpose of this pivotal study is to determine if intravenous Rezafungin is efficacious and safe in the prevention of invasive fungal diseases when compared to the standard antimicrobial regimen.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Candidemia, Mycoses, Fungal Infection, Fungemia, Invasive Candidiasis, Pneumocystis, Mold Infection, Invasive Fungal Disease, Prophylaxis of Invasive Fungal Infections, Aspergillus
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Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients with Chronic Spontaneous Urticaria (CSU)
NCT06162728
Recruiting
This trial will be performed as a three-part dose escalating clinical trial where Parts 1 is open label and Parts 2 and 3 are randomized, double-blinded, and placebo-controlled. The trial is intended to determine the safety and tolerability and assess the preliminary efficacy of briquilimab in adult participants with chronic spontaneous urticaria (CSU), who remain symptomatic despite treatment with H1 antihistamines and omalizumab. Additionally, pharmacokinetic (PK) properties of briquilimab, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Site 118, Birmingham, Alabama
Conditions: Chronic Spontaneous Urticaria
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Video Telehealth Exercise Training in Cystic Fibrosis
NCT04680403
Recruiting
The purpose of this research study is to begin an exercise program for patients with a cystic fibrosis (CF) exacerbation.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
01/31/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
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Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy
NCT04889430
Recruiting
The purpose of this Phase 3 study is to determine whether iptacopan (LNP023) is efficacious and safe for the treatment of aHUS in adult patients who are treatment naive to complement inhibitor therapy.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: Uni Of Alabama At Birmingham, Birmingham, Alabama
Conditions: Atypical Hemolytic Uremic Syndrome
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The Presence of a Therapy Dog Reduces Pain and Anxiety During Pediatric Elbow Pin Removal
NCT05830201
Recruiting
The purpose of this research study is to assess whether the presence of therapy dogs can reduce pain and anxiety in children ages 3 to 10 having pins removed from their elbow.
Gender:
ALL
Ages:
Between 3 years and 10 years
Trial Updated:
01/31/2025
Locations: UAB, Birmingham, Alabama
Conditions: Elbow Injury
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PYLARIFY® PET/CT or PET/MRI in Men with Favorable Intermediate Risk (FIR) Prostate Cancer
NCT06074510
Recruiting
The purpose of this study is to learn whether PYLARIFY PET imaging (study scan) can safely and accurately detect the presence or absence of prostate cancer growing beyond the prostate gland in men with favorable intermediate risk prostate cancer. Participants will receive a single dose of PYLARIFY injection followed by a single whole-body PET/CT or PET/MRI scan acquired at 1 to 2 hours after PYLARIFY injection. Participants with positive study scan results that are suspicious for prostate cance... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Prostate Cancer
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Vestibular Balance Therapy Intervention for Children
NCT05741515
Recruiting
The goal of this within groups clinical trial is to determine the feasibility of a home-based vestibular balance therapy program for children with vestibular hypofunction. The main questions to be answered are: 1) what is the intervention's feasibility and 2) what is the intervention's preliminary impact on function? Participants will receive a comprehensive battery of vestibular function and balance tests, then an 8-week home-based intervention to be done 5 times/week with weekly checks from th... Read More
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
01/30/2025
Locations: UAB, Birmingham, Alabama
Conditions: Vestibulocochlear Nerve Diseases, Vestibular Disorder, Bilateral Vestibular Loss
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Multi-Center Clean Air Randomized Controlled Trial in COPD
NCT06376994
Recruiting
This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/30/2025
Locations: University of Alabama, Lung Health Center, Birmingham, Alabama
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Register for Updates