There are currently 973 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama-Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
NCT05124808
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
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Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
NCT04396002
Recruiting
Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. More... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/06/2024
Locations: University of Alabama Birmingham, Birmingham, Alabama
Conditions: Primary Open Angle Glaucoma
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Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: University of Alabama, Birmingham, Alabama
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
NCT06263426
Recruiting
This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Hiv
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Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis
NCT05898477
Recruiting
The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.
Gender:
ALL
Ages:
All
Trial Updated:
06/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Lymphoma, Hemophagocytic Lymphohistiocytoses
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Histiocytic Disorder Follow-up Study
NCT05915208
Recruiting
The purpose of the study is to describe the burden of chronic health conditions, psychological dysfunction, chronic pain, healthcare utilization, worse health-related quality of life, overall mortality, and cause-specific mortality among individuals with histiocytic disorders
Gender:
ALL
Ages:
Between 0 years and 89 years
Trial Updated:
06/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Histiocytosis, Langerhans Cell Histiocytosis, Erdheim-Chester Disease, Rosai Dorfman Disease, Xanthogranuloma, Malignant Histiocytoses
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Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Children's of Alabama, Birmingham, Alabama
Conditions: Bronchiolitis Acute Viral
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Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
NCT06131021
Recruiting
Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak evidence on the use of systemic antibiotics and large heterogeneity across small scale studies, suggesting that larger pragmatic clinical trials would benefit clinical decision making. This will be a prospective, randomized, placebo-controlled trial, stratified by practic... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
05/30/2024
Locations: University of Alabame, Birmingham, Alabama
Conditions: Periodontitis, Periodontal Diseases, Periodontal Pocket
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Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
NCT03884374
Recruiting
This mechanistic clinical trial proposes to test whether a five-day course of mindfulness meditation training (MMT) and tDCS, and their combination, can enhance pain modulatory balance and pain-related brain function, reduce clinical pain, among African Americans and non-Hispanic whites with knee osteoarthritis (OA). This approach will provide evidence that targeting stress and pain-related brain function will reduce OA-related pain and ethnic group differences therein.
Gender:
ALL
Ages:
Between 45 years and 85 years
Trial Updated:
05/28/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Osteoarthritis of Knee
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Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia
NCT04380610
Recruiting
The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients
Gender:
ALL
Ages:
Between 5 years and 50 years
Trial Updated:
05/28/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Sickle Cell Disease, Renal Disease, Glomerular Disease
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Minds and Mentors Program- R33
NCT05363371
Recruiting
The proposed research effort will: The purpose of this study is as follows: 1. Test the effectiveness of the Minds and Mentors Program in a group treatment trial in which individuals using medications for opioid use disorder (MOUD) will be randomized in blocks of five to receive either the Minds and Mentors Program (n=120) or Twelve Step Facilitation (n=120). 2. Determine whether the MiMP: a) improves adherence to MOUD b) reduces the rate of relapse and cravings c) decreases self-reported anxi... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/26/2024
Locations: Birmingham Veteran Affairs Medical Center, Birmingham, Alabama +1 locations
Conditions: Opioid Use Disorder, Substance Use Disorders, Medication Assisted Treatment
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A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
NCT05757102
Recruiting
The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compared with FF/VI after 24 weeks of treatment.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
05/24/2024
Locations: GSK Investigational Site, Birmingham, Alabama
Conditions: Asthma
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