There are currently 872 clinical trials in Phoenix, Arizona looking for participants to engage in research studies. Trials are conducted at various facilities, including Phoenix Children's Hospital, GSK Investigational Site, Mayo Clinic Arizona and Mayo Clinic. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
NCT05812807
Recruiting
The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Cancer Center at Saint Joseph's, Phoenix, Arizona +1 locations
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma
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Avapritinib With Decitabine in Patients With SM-AHN
NCT06327685
Recruiting
Systemic mastocytosis with an associated hematologic neoplasm (SM-AHN) is a challenging disease to treat. Targeted KIT inhibitors have been approved for this indication based on their ability to control the mastocytosis portion of the disease, but patients frequently experience progression of the concomitant myeloid malignancy (i.e. the AHN). Using a combination approach to treat both aspects of the disease has the potential to provide enhanced disease control; however, overlapping toxicity is a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: Mayo Clinic - Arizona, Phoenix, Arizona
Conditions: Systemic Mastocytosis With an Associated Hematologic Neoplasm
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ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder
NCT05749055
Recruiting
The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/08/2024
Locations: IMA Clinical Research Phoenix, Phoenix, Arizona
Conditions: Generalized Anxiety Disorder
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Low Sodium Oxybate in Patients With Idiopathic Hypersomnia
NCT05837091
Recruiting
Low sodium oxybate has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of idiopathic hypersomnia. In this study, the researchers want to learn how low sodium oxybate impacts ability of people diagnosed with idiopathic hypersomnia to sleep for long periods of time. In addition, this study will use novel tools to determine when an individual is awake or asleep.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/08/2024
Locations: Mayo Clinic Arizona, Phoenix, Arizona
Conditions: Idiopathic Hypersomnia
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OCS™ Lung TOP Registry For Donor Lungs for Transplantation
NCT03639025
Recruiting
Single-arm, prospective, multi-center, post-approval U.S. registry
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: St. Joseph's Hospital and Medical Center, Phoenix, Arizona
Conditions: Lung Transplantation
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AMPLATZER PFO Occluder Post Approval Study
NCT03309332
Recruiting
The purpose of this single arm, multi-center study is to confirm the safety and effectiveness of the AMPLATZER™ PFO Occluder in the post Approval Setting.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/08/2024
Locations: St. Joseph's Hospital and Medical Center, Phoenix, Arizona
Conditions: Stroke, Patent Foramen Ovale
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Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma
NCT03889912
Recruiting
This study is researching an experimental drug called cemiplimab. The study is focused on Cutaneous Squamous Cell Carcinoma (CSCC) and Basal Cell Carcinoma (BCC). The aim of the study is to evaluate the safety and tolerability (how your body reacts to the drug) of cemiplimab (also known as REGN2810). The first part of the study tested several different doses of cemiplimab given weekly for 12 weeks. The study is also looking at several other research questions, including: What side effects ma... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Medical Dermatology Specialists, Phoenix, Arizona
Conditions: Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma
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A Study of AMDX-2011P in Participants With CAA
NCT05709314
Recruiting
The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P in participants with cerebral amyloid angiopathy (CAA).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Associated Retina Consultants, Phoenix, Arizona
Conditions: Cerebral Amyloid Angiopathy
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Neuropsychological and Behavioral Testing in Younger Patients With Cancer
NCT00772200
Recruiting
This research trial studies neuropsychological (learning, remembering or thinking) and behavioral outcomes in children and adolescents with cancer by collecting information over time from a series of tests.
Gender:
All
Ages:
1 month and above
Trial Updated:
04/05/2024
Locations: Phoenix Childrens Hospital, Phoenix, Arizona
Conditions: Childhood Malignant Neoplasm
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(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis
NCT05186753
Recruiting
This is a multi-part, randomized, double-blind, placebo-controlled Phase 2 clinical study comparing the safety and efficacy of bezuclastinib (CGT9486) plus best supportive care (BSC) with placebo plus BSC in patients with nonadvanced systemic mastocytosis (NonAdvSM), including indolent systemic mastocytosis and smoldering systemic mastocytosis, whose symptoms are not adequately controlled by BSC. This study will be conducted in three parts. Patients in Parts 1a, 1b and 2 will receive bezuclastin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Mayo Clinic Arizona, Phoenix, Arizona
Conditions: SSM, Mastocytosis, Indolent, Mastocytosis, Systemic, Mastocytosis
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Harmony TPV Post-Approval Study
NCT05077774
Recruiting
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (TPV) achieved by real-world implanters.
Gender:
All
Ages:
All
Trial Updated:
04/04/2024
Locations: Phoenix Children's, Phoenix, Arizona
Conditions: Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly, Pulmonary Regurgitation
Register for Updates
Pompe Pregnancy Sub-Registry
NCT00567073
Recruiting
This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the Pompe Registry, regardless of whether she is receiving disease-specific therapy (such as ERT with alglucosidase alfa or avalglucosidase alfa) and irrespective of the commercial product with which she may be treated. No experimental intervention is given; thus a patient will undergo clinical assessments and receive standa... Read More
Gender:
Female
Ages:
All
Trial Updated:
04/04/2024
Locations: Barrow Neurol Group Site Number : 840087, Phoenix, Arizona
Conditions: Glycogen Storage Disease Type II (GSD-II), Pompe Disease (Late-onset), Glycogenesis 2 Acid Maltase Deficiency
Register for Updates