There are currently 72 active clinical trials seeking participants for Type 1 Diabetes research studies. The states with the highest number of trials for Type 1 Diabetes participants are California, Texas, Colorado and Florida.
Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes
NCT06144554
Recruiting
This is a decentralized observational clinical registry to collect real-world evidence related to the safety and effectiveness of the Omnipod 5 system in children and adults with Type 1 Diabetes.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
05/14/2025
Locations: Circuit Clinical, Buffalo, New York
Conditions: Type 1 Diabetes
Register for Updates
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
NCT06338553
Recruiting
The goal of this study is to determine how a drug class called glucagon-like peptide-1 receptor agonists (GLP-1Ra) affects people during an early stage of Type 1 Diabetes undergoing clinical teplizumab treatment. This study involves giving participants a liquid meal under different conditions and observing how their bodies respond, focusing on blood sugar levels, insulin effectiveness, and blood vessel function. The meal tests are followed by two post-treatment tests, one with the GLP-1Ra drug a... Read More
Gender:
ALL
Ages:
Between 12 years and 50 years
Trial Updated:
05/13/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Type 1 Diabetes
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Improving Transition Care for Adolescents and Young Adults With Type 1 Diabetes
NCT05639088
Recruiting
The purpose of this research study is to evaluate a transition preparation program designed for adolescents and young adults (AYAs) with type 1 diabetes (T1D). This transition program will support AYAs as they prepare to transition from pediatric to adult endocrinology medical care and will also include a caregiver. Results from this study will inform clinical recommendations regarding self-management best practices for AYAs with T1D prior to transitioning to adult medical care.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
05/12/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Type 1 Diabetes
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Acetazolamide in Persons With Type 1 Diabetes - Crossover Trial
NCT06981234
Recruiting
The goal of this study is to learn about the effect of the study drug acetazolamide in individuals with Type 1 Diabetes. Specifically, whether acetazolamide provides benefits to the kidneys while minimizing any side effects of the drug. These changes will be measured by laboratory tests that tell us how well the kidneys are functioning.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: UC San Diego Altman Clinical & Translational Research Institute, La Jolla, California
Conditions: Type 1 Diabetes
Register for Updates
Safety and Feasibility of a Machine-Learning Bolus Priming Added to Existing Control Algorithm
NCT06728059
Recruiting
A randomized crossover trial assessing glycemic control using Reinforcement Learning trained Bolus Priming System (BPS_RL) added to the the Automated Insulin Delivery as Adaptive NETwork (AIDANET algorithm) compared to the original AIDANET algorithm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: University of Virginia Center for Diabetes Technology, Charlottesville, Virginia
Conditions: Type 1 Diabetes
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Safety Evaluation of MiniMed™ 780G System With DS5 CGM in Children
NCT06604871
Recruiting
The purpose of this study is to evaluate the safety of the MiniMed 780G insulin pump used in combination with the DS5 CGM in type 1 pediatric subjects (2-6 years of age) in a home setting.
Gender:
ALL
Ages:
Between 2 years and 6 years
Trial Updated:
05/06/2025
Locations: Stanford University, Palo Alto, California +7 locations
Conditions: Type 1 Diabetes
Register for Updates
Commercial or Open Source Closed Loop Impact on Pregnancy Study
NCT06654713
Recruiting
The goal of this observational study is to better understand what happens when pregnant people with type 1 diabetes (T1D) use automated insulin delivery (AID) systems. The main questions this study aims to answer are: * What are the maternal and neonatal outcomes with AID system use in pregnancy? * What are the glycemic outcomes with AID system use in pregnancy? * What are the behavioral and emotional outcomes with AID system use in pregnancy? Researchers will compare pregnant people who use c... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Type 1 Diabetes, Pregnancy, High Risk, Insulin Dependent Diabetes, Pregnancy Related
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An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
NCT06832410
Recruiting
This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/06/2025
Locations: University of Pittsburgh Medical Center Montefiore, Pittsburgh, Pennsylvania +2 locations
Conditions: Type 1 Diabetes, Kidney Transplant
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Description of Patients With Type 1 Diabetes Treated With Teplizumab
NCT06892002
Recruiting
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the destruction of pancreatic β cells. T1D pathogenesis progresses through several stages: Stage 1 T1D includes the presence of β cell autoimmunity and thus presence of islet autoantibodies, without the presence of dysglycemia and symptoms. Stage 2 T1D includes the presence of islet autoantibodies and dysglycemia, also with no symptoms. Stage 3 T1D includes presence of islet autoantibodies, overt hyperglycemia, and symptoms... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/06/2025
Locations: Atlanta Diabetes Associates, Atlanta, Georgia +4 locations
Conditions: Type 1 Diabetes
Register for Updates
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
NCT06914895
Recruiting
The main purpose of this study is to find out how well and how safely tirzepatide works in adults who have type 1 diabetes and obesity or overweight. Participation in the study will last about 49 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2025
Locations: Sansum Diabetes Research Institute, Goleta, California +147 locations
Conditions: Type 1 Diabetes, Obesity, Overweight
Register for Updates
Denosumab for Type 1 Diabetes
NCT06524960
Recruiting
Type 1 diabetes (T1D) arises from abnormal immune cell-mediated injury to beta cells that make insulin. The injured beta cells can then no longer make the needed amount of insulin to stay healthy. However, in the early stages of T1D, some beta cells are still alive and functioning. Treatment to protect the beta cells against injury at this time could slow the progress of disease. Denosumab is an approved treatment for osteoporosis (a disease that thins and weakens the bones), high blood calcium... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/24/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +2 locations
Conditions: Type 1 Diabetes
Register for Updates
BEAD-T1D: Building the Evidence to Address Disengagement in Type 1 Diabetes
NCT05488119
Recruiting
Youth with public insurance underutilize diabetes care, particularly diabetes technology which is associated with improvement in diabetes-specific outcomes. Thus, we urgently need studies to understand and increase diabetes technology utilization. This proposed research will (1) improve representation of youth in the literature, (2) address the gap in knowledge of barriers and promoters in youth, and (3) identify and address factors associated with diabetes technology uptake and utilization.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/22/2025
Locations: Stanford University, Stanford, California
Conditions: Type 1 Diabetes
Register for Updates