There are currently 403 clinical trials in Scottsdale, Arizona looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic in Arizona, Mayo Cliinic - Scottsdale, Mayo Clinic and Mayo Clinic Arizona. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer
NCT05068752
Recruiting
The purpose of this research is to determine the benefit of two oral chemotherapy drugs, Vemurafenib and Sorafenib, in individuals with KRAS mutated pancreatic cancer who have progressed on standard chemotherapy.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/18/2023
Locations: HonorHealth Research Institute, Scottsdale, Arizona
Conditions: Pancreas Cancer
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A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors
NCT03129139
Recruiting
A Phase I, Multicenter, Open-label, Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of Minnelide™Capsules given daily for 21 days followed by 7 days off schedule in patients with Advanced Solid Tumors
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: HonorHealth Research Institute, Scottsdale, Arizona
Conditions: Advanced Cancer, Gastric Cancer, Breast Cancer, Pancreatic Cancer, Prostate Cancer Metastatic, Colo-rectal Cancer, Solid Tumor, Solid Carcinoma, Solid Carcinoma of Stomach, Cancer of Stomach
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PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
NCT04683315
Recruiting
This is an open-label, phase II study in patients with resectable and borderline resectable pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/15/2023
Locations: HonorHealth Medical Group, Scottsdale, Arizona
Conditions: Pancreatic Cancer
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Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations
NCT04042831
Recruiting
This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene mutations. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/11/2023
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona
Conditions: Bile Duct Adenocarcinoma, Fanconi Anemia Complementation Group Gene Mutation, Metastatic Bile Duct Carcinoma, PTEN Gene Deletion
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Understanding the Challenges, Behavioral Patterns, and Preferences Towards Participation in Clinical Trials in Minority Patient Populations for the Development of a Personalized Clinical Trial Educational Platform to Increase Participation in Clinical Trials Among Underserved Cancer Patients
NCT04630431
Recruiting
This clinical trial investigates the challenges, behavioral patterns, and preferences towards participation in clinical trials in minority patient populations in order to develop a personalized clinical trial educational platform to increase participation in clinical trials among underserved cancer patients. Learning more about patients' understanding of clinical trials may help identify barriers that limit patient's participation. Information gathered from this trial will be used to develop edu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
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A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
NCT05071300
Recruiting
The purpose of this study is to evaluate the safety and tolerability of extended dosing with Eplontersen in participants with hereditary transthyretin-mediated amyloid polyneuropathy (hATTR-PN).
Gender:
All
Ages:
18 years and above
Trial Updated:
10/04/2023
Locations: Mayo Clinic, Scottsdale, Arizona
Conditions: Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
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Dupilumab and Milk OIT for the Treatment of Cow's Milk Allergy
NCT04148352
Recruiting
This is a phase 2, multicenter, randomized, double-blind, parallel group, 2 arm study in approximately 40 subjects aged 4 to 50 years, inclusive, who are allergic to cow's milk. The primary objective is to assess whether dupilumab as an adjunct to milk oral immunotherapy (OIT) compared to placebo improves the safety of milk OIT and rates of desensitization, defined as an increase in the proportion of subjects who pass a double-blind placebo-controlled food challenge (DBPCFC) to at least 2040 mg... Read More
Gender:
All
Ages:
Between 4 years and 50 years
Trial Updated:
10/02/2023
Locations: Mayo Clinic, Scottsdale, Arizona
Conditions: Allergies Food Milk
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L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer
NCT04203641
Recruiting
This study will evaluate the safety and tolerability of escalating doses of L-DOS47 in combination with doxorubicin, as well as preliminary anti-tumor activity in patients with previously treated advanced pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: Scottsdale Healthcare Hospitals DBA HonorHealth, Scottsdale, Arizona
Conditions: Pancreas Cancer
Register for Updates
A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors
NCT05329103
Recruiting
This is a first-in-human, dose escalation, repeat-dose, multi-center, open-label study evaluating safety, tolerability, PK, and preliminary antitumor activity of PEEL-224 in patients with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: HonorHealth Research Institiute, Scottsdale, Arizona
Conditions: Advanced Solid Tumor
Register for Updates
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
NCT05033288
Recruiting
This study compares carbon ion therapy, surgery, and proton therapy to determine if one has better disease control and fewer side effects. There are three types of radiation treatment used for pelvic bone sarcomas: surgery with or without photon/proton therapy, proton therapy alone, and carbon ion therapy alone. The purpose of this study is to compare quality of life among patients treated for pelvic bone sarcomas across the world, and to determine if carbon ion therapy improves quality of life... Read More
Gender:
All
Ages:
15 years and above
Trial Updated:
09/18/2023
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona
Conditions: Bone Sarcoma, Chondrosarcoma, Chordoma, Ewing Sarcoma of Bone, Pelvic Rhabdomyosarcoma
Register for Updates
Noninterventional Study Evaluating Parkinson's Disease Diary Use
NCT05363046
Recruiting
This study aims to evaluate the impact of the frequency of assessments on the variability over time, reliability, and compliance for the Parkinson's disease (PD) diary in patients with PD in whom medications do not provide adequate control of symptoms.
Gender:
All
Ages:
Between 39 years and 70 years
Trial Updated:
09/12/2023
Locations: Mayo Clinic Neurology, Scottsdale, Arizona
Conditions: Parkinson's Disease
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ORB-011 In Patients With Advanced Solid Tumors
NCT05947474
Recruiting
The goal of this clinical research study is to determine if an investigational new drug, named ORB-011, developed by Orionis Biosciences is safe and can be tolerated in people diagnosed with an advanced solid tumor. The study also aims to find the biologically optimal dose of the study medicine by assessing the safety and potential activity in the treatment of solid tumors. There are three phases to this study: screening, treatment and end of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2023
Locations: Honor Health Research Institute, Scottsdale, Arizona
Conditions: Advanced Solid Cancer
Register for Updates