Arizona is currently home to 1790 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Phoenix, Tucson, Scottsdale and Mesa. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Stress Hydrocortisone In Pediatric Septic Shock
NCT03401398
Recruiting
SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive hydrocortisone prescribed for children with fluid and vasoactive-inotropic refractory septic shock. It is hypothesized that adjunctive hydrocortisone will significantly reduce the proportion of children with poor outcomes, defined as death or severely impaired health-related quality of life (HRQL), as assessed at 28 days follo... Read More
Gender:
All
Ages:
Between 1 month and 17 years
Trial Updated:
02/02/2023
Locations: University of Arizona Medical Centre, Tucson, Arizona
Conditions: Septic Shock
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Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+
NCT05502055
Recruiting
Study Rationale: Older adults who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have worse health than non-LGBTQ+ older adults. They and their care partners face greater barriers to getting healthcare and support from friends and family. This is because of lifelong stigma, discrimination, and isolation often separated from their families. Parkinson disease (PD) is a disease that usually appears in older age, so there may be many LGBTQ+ elders with PD, but there is currently... Read More
Gender:
All
Ages:
All
Trial Updated:
01/30/2023
Locations: Creighton University Phoenix, Phoenix, Arizona
Conditions: Parkinson Disease, Sexual Orientation
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A Study of ZN-c3 in Participants With Solid Tumors
NCT04158336
Recruiting
This is a Phase 1 open-label, multicenter study of ZN-c3 monotherapy which consists of Dose Escalation, a Food Effect Cohort, and Dose Expansion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Site 0102, Tucson, Arizona
Conditions: Solid Tumor
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Improving Hypertension Medication Adherence for Older Adults
NCT05610059
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/26/2023
Locations: University of Arizona, Tucson, Arizona
Conditions: Aging, Medication Adherence, Hypertension
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Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)
NCT04502316
Recruiting
The purpose of this registry is to develop valid scientific evidence of the safety and benefit of Barostim Therapy in the commercial setting in patients with heart failure with reduced ejection fraction (HFrEF) that were recently implanted with the Barostim System.
Gender:
All
Ages:
All
Trial Updated:
01/21/2023
Locations: Chan Heart Rhythm Institute, Mesa, Arizona
Conditions: Heart Failure
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Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC
NCT05199818
Recruiting
The phase 3 study is to compare the efficacy and safety of palonosetron, a long-acting 5-HT3 receptor antagonist, by buccal film delivery compared to IV injection for the prevention of chemotherapy-induced nausea and vomiting. Subjects receive a single dose of palonosetron prior to moderately emetogenic chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/19/2023
Locations: Ironwood Cancer & Research Centers, Chandler, Arizona
Conditions: Chemotherapy-induced Nausea and Vomiting
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Mitochondrial Methylation in Type 2 Diabetes
NCT04126551
Recruiting
The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
01/13/2023
Locations: Clinical and Translational Research Center (CaTS), Tucson, Arizona
Conditions: Obesity, Diabetes Mellitus, Type 2, Insulin Resistance, Overweight
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Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma
NCT04840069
Recruiting
The purpose of the this study is to see if the use of a PET scan with 18F-fluciclovine (PET or Fluciclovine PET) in addition to the normal radiation planning imaging procedures (MRI and CT scan) will help determine the areas where the radiation therapy is to be delivered. It is also a goal of the study to determine if subjects live longer when treatment plans for radiation therapy are designed using a Fluciclovine PET scan, as well as MRI and CT scans. We will also collect information on if and... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: St. Joseph's Hospital and Medical Center, Phoenix, Arizona
Conditions: Newly Diagnosed Glioblastoma
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Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia
NCT04527224
Recruiting
This study is an open-label, single-arm study to evaluate the safety and efficacy of Astrostem-V, allogenic adipose tissue derived mesenchymal stem cells (AdMSC), in patients with COVID-19 pneumonia. After each subject completes 12-Weeks visit (Visit 12) and the data management team confirms all individual data have no issue, the individual database will be locked and the blinding will be open for the statistical analysis.
Gender:
All
Ages:
Between 19 years and 80 years
Trial Updated:
01/09/2023
Locations: Medical Advancement Center of Arizona, Phoenix, Arizona
Conditions: Covid19 Pneumonia
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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
NCT04373564
Recruiting
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (G... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
01/08/2023
Locations: Scottsdale Medical Imaging, LLC, Scottsdale, Arizona
Conditions: Motor Function, Cognitive Function, Contrast Media
Register for Updates
Safety & Effectiveness of TENS Weight Management Compared to a Sham
NCT05675384
Recruiting
This is a multicenter, randomized, blinded, parallel group, controlled study intended to evaluate the safety and effectiveness of treating overweight and Class 1 obese patients with the Elira System (TENS active treatment) combined with a moderate intensity lifestyle follow-up compared to participants using the sham (control) device combined with a moderate intensity lifestyle follow-up
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
01/06/2023
Locations: Honor Health, Scottsdale, Arizona
Conditions: Obesity, Mild
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A Study of a Multi-Modal Sensor Patch for Real-Time Physiological Monitoring and Inference
NCT05581290
Recruiting
The purpose of this research is to validate the prototype AI-Flex device. Researchers at Mayo Clinic developed a new a flexible multi-modal bio-sensing device, AI-Flex, with integrated artificial intelligence (AI) capability. Integration of sensing and AI analysis on the same device removes the need for data storage on the cloud for later analysis. The goal of the device is to allow real-time monitoring of patient health and timely intervention based on patient health condition. It is hoped that... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/05/2023
Locations: Imon Banerjee, Phoenix, Arizona
Conditions: Cardiac Disease
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