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Carboplatin Treatment Options in Canada
A collection of 334 research studies where Carboplatin is the interventional treatment. These studies are located in the Canada . Carboplatin is used for conditions such as Non-Small Cell Lung Cancer, Ovarian Cancer and Lung Cancer.
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A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Recruiting
The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer.
The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2025
Locations: Southern Cancer Center, PC, Daphne, Alabama +190 locations
Southern Cancer Center, PC, Daphne, Alabama
Local Institution - 0283, Hot Springs, Arkansas
Florida Cancer Specialists - South, Fort Myers, Florida
Mid Florida Hematology and Oncology Center, Orange City, Florida
Florida Cancer Specialists - North, Saint Petersburg, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital, Marietta, Georgia
Illinois Cancer Care, Peoria, Illinois
Local Institution - 0037, Minneapolis, Minnesota
University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
Duke Cancer Institute, Durham, North Carolina
Oncology Hematology Care, Cincinnati, Ohio
Local Institution - 0239, Cleveland, Ohio
Sanford Cancer Center, Sioux Falls, South Dakota
Local Institution - 0307, Knoxville, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
Texas Oncology - Central/South Texas, Austin, Texas
Texas Oncology - Northeast Texas, Tyler, Texas
Oncology & Hematology Associates of Southwest Virginia, Inc., Roanoke, Virginia
Local Institution - 0339, Edmonds, Washington
Swedish Medical Center, Seattle, Washington
Local Institution - 0007, Tacoma, Washington
Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Buenos Aires
Hospital Italiano de Buenos Aires, ABB, Ciudad Autónoma De Buenos Aires
Local Institution - 0100, Buenos Aires, Ciudad Autónoma De Buenos Aires
Clinica Adventista Belgrano, Caba, Ciudad Autónoma De Buenos Aires
Instituto Médico Río Cuarto, Río Cuarto, Córdoba
GenesisCare - Campbelltown, Campbelltown, New South Wales
Nepean Hospital, Penrith, New South Wales
Gallipoli Medical Research Ltd, Brisbane, Queensland
Grampians Health, Ballarat Central, Victoria
St. John of God Murdoch Hospital, Murdoch, Western Australia
Klinikum Wels-Grieskirchen GmbH, Wels, Oberösterreich
Medizinische Universität Graz, Graz, Steiermark
Kepler Universitätsklinikum, Linz, Not set
Landeskrankenhaus Rankweil, Rankweil, Not set
Local Institution - 0250, Wien, Not set
Local Institution - 0198, Brussels, Bruxelles-Capitale, Région De
UZ Gent, Gent, Oost-Vlaanderen
VITAZ, Sint-Niklaas, Oost-Vlaanderen
Local Institution - 0180, Leuven, Vlaams-Brabant
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, Not set
Local Institution - 0166, Fortaleza, Ceará
Local Institution - 0165, Porto Alegre, Rio Grande Do Sul
Local Institution - 0169, Porto Alegre, Rio Grande Do Sul
Local Institution - 0170, Santa Cruz do Sul, Rio Grande Do Sul
Local Institution - 0163, Itajaí, Santa Catarina
Local Institution - 0178, Barretos, São Paulo
Local Institution - 0111, Sao Paulo, São Paulo
Local Institution - 0289, Edmonton, Alberta
CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski, Rimouski, Quebec
IUCPQ, Quebec, Not set
Orlandi Oncologia, Santiago, Región Metropolitana De Santiago
Fundacion Arturo Lopez Perez (FALP), Santiago, Región Metropolitana De Santiago
Pontificia Universidad Catolica de Chile, Santiago, Región Metropolitana De Santiago
Bradfordhill, Santiago, Región Metropolitana De Santiago
Oncocentro Apys, Viña del Mar, Valparaíso
Beijing Cancer hospital, Beijing, Beijing
Beijing Chest Hospital,Capital Medical University, Beijing, Beijing
Chongqing University Cancer Hospital, Chongqing, Chongqing
Fujian Cancer Hospital, Fuzhou, Fujian
Local Institution - 0212, Xiamen, Fujian
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong
Local Institution - 0227, Harbin, Heilongjiang
Local Institution - 0208, Wuhan, Hubei
Hubei Cancer Hospital, Wuhan, Hubei
Local Institution - 0216, Changsha, Hunan
Local Institution - 0233, Nanchang, Jiangxi
Jilin Province Tumor Hospital, Changchun, Jilin
Local Institution - 0235, Shenyang, Liaoning
Xi'an International Medical Center Hospital, Xi'an, Shaanxi
Shandong Cancer Hospital, Jinan, Shandong
Local Institution - 0206, Shanghai, Shanghai
Zhongshan Hospital,Fudan University, Shanghai, Shanghai
Sichuan Cancer hospital, Chengdu, Sichuan
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang
Shanghai East Hospital, Shanghai, Not set
Masarykuv onkologicky ustav, Brno, Brno-město
Nemocnice AGEL Ostrava - Vitkovice a.s., Ostrava, Ostrava Město
Fakultni Thomayerova nemocnice, Prague, Praha 4
Fakultni nemocnice Olomouc, Olomouc, Not set
Hôpital Arnaud de Villeneuve - CHU Montpellier, Montpellier, Hérault
Chu Grenoble Alpes, La Tronche, Isère
CHU Lille - Institut Coeur Poumon, Lille Cedex, Nord
L Hopital Nord Ouest, Gleize, Rhône
Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône
Centre Hospitalier Intercommunal de Créteil, Créteil, Val-de-Marne
Gustave Roussy, Villejuif, Val-de-Marne
Assistance Publique Hôpitaux de Marseille - Hôpital Nord, Marseille, Not set
Institut Curie, Paris, Not set
Centre Hospitalier de Cornouaille Quimper - Concarneau, Quimper, Not set
Krankenhaus Nordwest GmbH, Frankfurt, Hessen
Pius Hospital Oldenburg, Oldenburg, Niedersachsen
Klinikum Köln-Merheim, Köln, Nordrhein-Westfalen
Krankenhaus Martha-Maria Halle-Dölau, Halle, Sachsen-Anhalt
Local Institution - 0257, Bad Berka, Thüringen
Local Institution - 0263, Berlin, Not set
Asklepios Klinik Gauting GmbH, Gauting, Not set
LungenClinic Grosshansdorf, Grosshansdorf, Not set
Thoraxklinik-Heidelberg gGmbH, Heidelberg, Not set
Robert Bosch Krankenhaus GmbH, Stuttgart, Not set
Errikos Dunant Hospital Center, Athens, Attikí
Thoracic General Hospital of Athens "I Sotiria", Athens, Attikí
"Theagenio" Cancer Hospital of Thessaloniki, Thessaloniki, Kentrikí Makedonía
European Interbalkan Medical Center, Thessaloniki, Thessaloníki
University General Hospital of Larissa, Larissa, Thessalía
Local Institution - 0278, New Delhi, Delhi
Local Institution - 0274, Bengaluru, Karnataka
Local Institution - 0271, Madurai, Tamil Nadu
Local Institution - 0277, Varanasi, Uttar Pradesh
Local Institution - 0273, Kolkata, West Bengal
Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Lombardia
Istituto Nazionale Tumori Regina Elena, Rome, Roma
AO Santa Maria della Misericordia, Perugia, Umbria
Casa di Cura Dott. Pederzoli, Peschiera del Garda, Verona
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set
Istituto Europeo di Oncologia IRCCS, Milano, Not set
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime
Kurume University Hospital, Kurume, Fukuoka
Hokkaido University Hospital, Sapporo, Hokkaido
Kobe City Medical Center General Hospital, Kobe-shi, Hyogo
Kanazawa University Hospital, Kanazawa, Ishikawa
Kanagawa Cardiovascular and Respiratory Center, Yokohama, Kanagawa
Sendai Kousei Hospital, Sendai, Miyagi
Nara Medical University Hospital, Kashihara city, Nara
Kurashiki Central Hospital, Kurashiki, Okayama
Kansai Medical University Hospital, Hirakata, Osaka
Kindai University Hospital- Osakasayama Campus, Osaka Sayama, Osaka
Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Osaka
Saitama Medical University International Medical Center, Hidaka, Saitama
Saitama Prefectural Cancer Center, Ina-machi, Saitama
Hamamatsu University Hospital, Hamamatsu, Shizuoka
Nippon Medical School Hospital, Bunkyo-ku, Tokyo
The Cancer Institute Hospital of JFCR, Koto, Tokyo
Fukushima Medical University, Fukushima, Not set
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do [Chungbuk]
Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do
Ajou University Hospital, Suwon-si, Kyǒnggi-do
Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul]
Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]
Keimyung University Dongsan Hospital, Daegu, Taegu-Kwangyǒkshi
Local Institution - 0311, Kuching, Sarawak
Local Institution - 0310, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Local Institution - 0312, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Local Institution - 0148, Pachuca, Hidalgo
Local Institution - 0146, Guadalajara, Jalisco
Local Institution - 0147, Monterrey, Nuevo León
Local Institution - 0145, Puebla, Not set
Amsterdam UMC, locatie VUmc, Amsterdam, Noord-Holland
Ziekenhuis Rijnstate, Arnhem, Not set
University Medical Center Groningen, Groningen, Not set
Szpital Specjalistyczny w Prabutach Spolka z o.o., Prabuty, Pomorskie
Przychodnia Lekarska KOMED, Konin, Wielkopolskie
Pratia Poznań, Poznań, Wielkopolskie
Centrum Onkologii im. Prof. Franciszka Lukaszczyka, Bydgoszcz, Not set
Instytut Centrum Zdrowia Matki Polki, Łódź, Łódzkie
SC Memorial Healthcare International SRL, Bucharest, București
Institutul Oncologic Bucuresti, Bucharest, București
SC Radiotherapy Center Cluj SRL, Florești, Cluj
Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj
Institutul Oncologic Cluj, Cluj, Not set
S.C. Centrul de Oncologie Euroclinic S.R.L., Iași, Not set
Institutul Regional de Oncologie, Iași, Not set
CHUS - Hospital Clinico Universitario, Santiago de Compostela, A Coruña [La Coruña]
Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]
Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya [Cataluña]
Hospital Universitario de Jaen, Jaen, Jaén
Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De
Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad De
Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De
Hospital General Universitario de Valencia, Valencia, Valenciana, Comunitat
Local Institution - 0299, Sevilla, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Kantonsspital Graubünden, Chur, Not set
Kantonsspital Winterthur, Winterthur, Not set
UniversitätsSpital Zürich, Zürich, Not set
Local Institution - 0158, Cigli, İzmir
Local Institution - 0154, Adana, Not set
Local Institution - 0157, Ankara, Not set
Local Institution - 0177, Ankara, Not set
Local Institution - 0153, Istanbul, Not set
Local Institution - 0197, London, London, City Of
James Cook University Hospital, Central Middlesbrough, Middlesbrough
Aberdeen Royal Infirmary, Aberdeen, Not set
Local Institution - 0108, Leicester, Not set
The Christie NHS Foundation Trust, Manchester, Not set
The Clatterbridge Cancer Centre, Wirral, Not set
Conditions: Extensive-Stage Small Cell Lung Cancer
Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer
Recruiting
This phase II trial tests the addition of BMS-986016 (relatlimab) to the usual immunotherapy after initial treatment for nasopharyngeal cancer that has come back after a period of improvement (recurrent) or that has spread from where it first started (primary site) to other places in the body (metastatic). Relatlimab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. The usual approach of treatment is initial treatment with chemotherapy such as the co... Read More
This phase II trial tests the addition of BMS-986016 (relatlimab) to the usual immunotherapy after initial treatment for nasopharyngeal cancer that has come back after a period of improvement (recurrent) or that has spread from where it first started (primary site) to other places in the body (metastatic). Relatlimab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. The usual approach of treatment is initial treatment with chemotherapy such as the combination of cisplatin (or carboplatin) and gemcitabine, along with immunotherapy such as nivolumab. After the initial treatment is finished, patients may continue to receive additional immunotherapy. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Gemcitabine is a chemotherapy drug that blocks the cells from making deoxyribonucleic acid (DNA) and may kill cancer cells. Giving BMS-986016 in addition to the usual immunotherapy after initial treatment may extend the time without the tumor cells growing or spreading longer than the usual approach in patients with recurrent or metastatic nasopharyngeal cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2025
Locations: Kaiser Permanente Dublin, Dublin, California +72 locations
Kaiser Permanente Dublin, Dublin, California
Kaiser Permanente-Fremont, Fremont, California
Kaiser Permanente-Fresno, Fresno, California
Keck Medicine of USC Koreatown, Los Angeles, California
Los Angeles General Medical Center, Los Angeles, California
USC / Norris Comprehensive Cancer Center, Los Angeles, California
Kaiser Permanente-Modesto, Modesto, California
USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California
Kaiser Permanente-Oakland, Oakland, California
Stanford Cancer Institute Palo Alto, Palo Alto, California
Kaiser Permanente-Roseville, Roseville, California
Kaiser Permanente Downtown Commons, Sacramento, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
Kaiser Permanente-South Sacramento, Sacramento, California
Kaiser Permanente-San Francisco, San Francisco, California
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California
Kaiser Permanente San Leandro, San Leandro, California
Kaiser San Rafael-Gallinas, San Rafael, California
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California
Kaiser Permanente-Santa Rosa, Santa Rosa, California
Kaiser Permanente-South San Francisco, South San Francisco, California
Kaiser Permanente-Vallejo, Vallejo, California
Kaiser Permanente-Walnut Creek, Walnut Creek, California
Emory University Hospital Midtown, Atlanta, Georgia
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho
Northwestern University, Chicago, Illinois
University of Illinois, Chicago, Illinois
Carle at The Riverfront, Danville, Illinois
Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois
Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois
Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
Northwestern Medicine Orland Park, Orland Park, Illinois
Carle Cancer Center, Urbana, Illinois
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
Heartland Oncology and Hematology LLP, Council Bluffs, Iowa
Methodist Jennie Edmundson Hospital, Council Bluffs, Iowa
Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ, Council Bluffs, Iowa
Mercy Hospital South, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Community Hospital of Anaconda, Anaconda, Montana
Billings Clinic Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Logan Health Medical Center, Kalispell, Montana
Community Medical Center, Missoula, Montana
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska
Nebraska Methodist Hospital, Omaha, Nebraska
Oncology Associates PC, Omaha, Nebraska
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma
Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
ProHealth D N Greenwald Center, Mukwonago, Wisconsin
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin
University Health Network-Princess Margaret Hospital, Toronto, Ontario
Chinese University of Hong Kong-Prince of Wales Hospital, Shatin, Not set
National University Hospital Singapore, Singapore, Not set
National Cancer Centre Singapore, Singapore, Not set
Conditions: Metastatic Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Carcinoma, Stage IV Nasopharyngeal Carcinoma AJCC v8
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Not Yet Recruiting
A Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI Therapy
A Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI Therapy Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/31/2025
Locations: Local Institution - 0154, Orange, California +147 locations
Local Institution - 0154, Orange, California
Local Institution - 0139, Edwards, Colorado
Local Institution - 0085, Gainesville, Florida
Local Institution - 0143, Columbus, Georgia
Local Institution - 0153, Chicago, Illinois
Local Institution - 0067, Boston, Massachusetts
Local Institution - 0091, Saint Louis, Missouri
Local Institution - 0090, New York, New York
Local Institution - 0158, New York, New York
Local Institution - 0186, Rochester, New York
Local Institution - 0087, Cleveland, Ohio
Local Institution - 0038, Portland, Oregon
Local Institution - 0205, Philadelphia, Pennsylvania
Local Institution - 0088, Pittsburgh, Pennsylvania
Local Institution - 0093, Nashville, Tennessee
Local Institution - 0025, Houston, Texas
Local Institution - 0173, San Antonio, Texas
Local Institution - 0145, Charlottesville, Virginia
Local Institution - 0138, Richmond, Virginia
Local Institution - 0008, Ciudad Autónoma de Buenos Aires, Buenos Aires
Local Institution - 0004, ABB, Ciudad Autónoma De Buenos Aires
Local Institution - 0094, Cordoba, Córdoba
Local Institution - 0161, Auderghem, Bruxelles-Capitale, Région De
Local Institution - 0022, Yvoir, Namur
Local Institution - 0023, Gent, Oost-Vlaanderen
Local Institution - 0024, Sint-Niklaas, Oost-Vlaanderen
Local Institution - 0190, Calgary, Alberta
Local Institution - 0183, Toronto, Ontario
Local Institution - 0184, Chicoutimi, Quebec
Local Institution - 0185, Montreal, Quebec
Local Institution - 0006, Santiago, Región Metropolitana De Santiago
Local Institution - 0005, Santiago, Región Metropolitana De Santiago
Local Institution - 0007, Santiago, Región Metropolitana De Santiago
Local Institution - 0244, Beijing, Beijing
Local Institution - 0243, Wuhan, Hubei
Local Institution - 0257, Shenyang, Liaoning
Local Institution - 0258, Taiyuan, Shanxi
Local Institution - 0229, Valledupar, Cesar
Local Institution - 0228, Bogotá, Cundinamarca
Local Institution - 0227, Montería, Córdoba
Local Institution - 0226, Cali, Valle Del Cauca
Local Institution - 0014, Strasbourg, Alsace
Local Institution - 0017, Toulouse, Haute-Garonne
Local Institution - 0018, La Tronche, Isère
Local Institution - 0170, Saint Herblain, Loire-Atlantique
Local Institution - 0010, Lille, Nord-Pas-de-Calais
Local Institution - 0162, Bron, Rhône
Local Institution - 0019, Villejuif, Val-de-Marne
Local Institution - 0012, Marseille, Not set
Local Institution - 0011, Paris, Not set
Local Institution - 0015, Paris, Not set
Local Institution - 0207, Esslingen, Baden-Württemberg
Local Institution - 0238, Esslingen, Baden-Württemberg
Local Institution - 0212, Stuttgart, Baden-Württemberg
Local Institution - 0236, Donauwörth, Bayern
Local Institution - 0209, Oldenburg, Niedersachsen
Local Institution - 0213, Köln, Nordrhein-Westfalen
Local Institution - 0208, Chemnitz, Sachsen
Local Institution - 0211, Berlin, Not set
Local Institution - 0215, Gauting, Not set
Local Institution - 0210, Heidelberg, Not set
Local Institution - 0054, Athens, Attikí
Local Institution - 0060, Chaidari, Attikí
Local Institution - 0062, Thessaloniki, Thessaloníki
Local Institution - 0070, New Delhi, Delhi
Local Institution - 0083, Ahmedabad, Gujarat
Local Institution - 0072, Gurugram, Haryana
Local Institution - 0069, Bengaluru, Karnataka
Local Institution - 0077, Mumbai, Maharashtra
Local Institution - 0071, Mumbai, Maharashtra
Local Institution - 0078, Howrah, West Bengal
Local Institution - 0028, Ravenna, Emilia-Romagna
Local Institution - 0036, Aviano, Friuli-Venezia Giulia
Local Institution - 0031, Orbassano, Piemonte
Local Institution - 0137, Avellino, Not set
Local Institution - 0032, Milano, Not set
Local Institution - 0034, Napoli, Not set
Local Institution - 0029, Parma, Not set
Local Institution - 0196, Nagoya, Aichi
Local Institution - 0191, Kashiwa, Chiba
Local Institution - 0203, Toon, Ehime
Local Institution - 0201, Kurume, Fukuoka
Local Institution - 0217, Sapporo, Hokkaido
Local Institution - 0199, Nishinomiya, Hyogo
Local Institution - 0193, Yokohama, Kanagawa
Local Institution - 0192, Sendai, Miyagi
Local Institution - 0200, Kurashiki, Okayama
Local Institution - 0198, Hirakata, Osaka
Local Institution - 0204, Osaka-sayama, Osaka
Local Institution - 0194, Ina-machi, Saitama
Local Institution - 0197, Hamamatsu, Shizuoka
Local Institution - 0195, Nagaizumi-cho,Sunto-gun, Shizuoka
Local Institution - 0202, Koto-ku, Tokyo
Local Institution - 0089, Cheongju-si, Chungcheongbuk-do [Chungbuk]
Local Institution - 0043, Goyang-si, Kyǒnggi-do
Local Institution - 0044, Seongnam, Kyǒnggi-do
Local Institution - 0046, Suwon-si, Kyǒnggi-do
Local Institution - 0095, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0045, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0092, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0042, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0225, Mexico City, Distrito Federal
Local Institution - 0224, Oaxaca de Juarez, Oaxaca
Local Institution - 0222, Chihuahua, Not set
Local Institution - 0223, Mexico City, Not set
Local Institution - 0163, Harderwijk, Gelderland
Local Institution - 0216, Amsterdam, Noord-Holland
Local Institution - 0164, Amsterdam, Noord-Holland
Local Institution - 0103, Drammen, Buskerud
Local Institution - 0106, Bergen, Hordaland
Local Institution - 0105, Oslo, Not set
Local Institution - 0220, Lublin, Lubelskie
Local Institution - 0231, Gdynia, Pomorskie
Local Institution - 0219, Bydgoszcz, Not set
Local Institution - 0120, Bucharest, București
Local Institution - 0123, Bucharest, București
Local Institution - 0132, Florești, Cluj
Local Institution - 0130, Craiova, Dolj
Local Institution - 0115, Bucharest, Not set
Local Institution - 0133, Cluj, Not set
Local Institution - 0124, Iași, Not set
Local Institution - 0119, Iași, Not set
Local Institution - 0263, Singapore, Not set
Local Institution - 0262, Singapore, Not set
Local Institution - 0177, Barcelona, Catalunya [Cataluña]
Local Institution - 0175, Madrid, Madrid, Comunidad De
Local Institution - 0206, Madrid, Madrid, Comunidad De
Local Institution - 0176, Madrid, Madrid, Comunidad De
Local Institution - 0181, Majadahonda, Madrid, Comunidad De
Local Institution - 0178, Málaga, Not set
Local Institution - 0182, Sevilla, Not set
Local Institution - 0180, València, Not set
Local Institution - 0179, Zaragoza, Not set
Local Institution - 0188, Baden, Aargau
Local Institution - 0187, st.Gallen, Sankt Gallen
Local Institution - 0189, Bellinzona, Not set
Local Institution - 0053, Kaohsiung, Not set
Local Institution - 0050, Taichung, Not set
Local Institution - 0049, Tainan, Not set
Local Institution - 0048, Taipei, Not set
Local Institution - 0047, Taipei, Not set
Local Institution - 0160, Taipei, Not set
Local Institution - 0265, Bangkok, Krung Thep Maha Nakhon
Local Institution - 0264, Bangkok, Not set
Local Institution - 0266, Songkhla, Not set
Local Institution - 0110, Glasgow, Glasgow City
Local Institution - 0061, London, Kensington And Chelsea
Local Institution - 0140, London, London, City Of
Conditions: Non-Small Cell Lung Cancer
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Recruiting
This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuximab is a monoclonal antibody that binds to a molecule called GD2, which is found on the surface of neuroblastoma cells, but is not present on many healthy or normal cells in the body. When dinutuximab bi... Read More
This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuximab is a monoclonal antibody that binds to a molecule called GD2, which is found on the surface of neuroblastoma cells, but is not present on many healthy or normal cells in the body. When dinutuximab binds to the neuroblastoma cells, it helps signal the immune system to kill the tumor cells. This helps the cells of the immune system kill the cancer cells, this is a type of immunotherapy. When chemotherapy and immunotherapy are given together, during the same treatment cycle, it is called chemoimmunotherapy. This clinical trial randomly assigns patients to receive either standard chemotherapy and surgery or chemoimmunotherapy (chemotherapy plus dinutuximab) and surgery during Induction therapy. Chemotherapy drugs administered during Induction include, cyclophosphamide, topotecan, cisplatin, etoposide, vincristine, and doxorubicin. These drugs work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing or by stopping them from spreading. Upon completion of 5 cycles of Induction therapy, a disease evaluation is completed to determine how well the treatment worked. If the tumor responds to therapy, patients receive a tandem transplantation with stem cell rescue. If the tumor has little improvement or worsens, patients receive chemoimmunotherapy on Extended Induction. During Extended Induction, dinutuximab is given with irinotecan, temozolomide. Patients with a good response to therapy move on to Consolidation therapy, when very high doses of chemotherapy are given at two separate points to kill any remaining cancer cells. Following, transplant, radiation therapy is given to the site where the cancer originated (primary site) and to any other areas that are still active at the end of Induction. The final stage of therapy is Post-Consolidation. During Post-Consolidation, dinutuximab is given with isotretinoin, with the goal of maintaining the response achieved with the previous therapy. Adding dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy may be better at treating children with newly diagnosed high-risk neuroblastoma. Read Less
Gender:
ALL
Ages:
30 years and below
Trial Updated:
07/31/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +158 locations
Children's Hospital of Alabama, Birmingham, Alabama
USA Health Strada Patient Care Center, Mobile, Alabama
Banner Children's at Desert, Mesa, Arizona
Phoenix Childrens Hospital, Phoenix, Arizona
Banner University Medical Center - Tucson, Tucson, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Kaiser Permanente Downey Medical Center, Downey, California
City of Hope Comprehensive Cancer Center, Duarte, California
Loma Linda University Medical Center, Loma Linda, California
Miller Children's and Women's Hospital Long Beach, Long Beach, California
Children's Hospital Los Angeles, Los Angeles, California
Cedars Sinai Medical Center, Los Angeles, California
Mattel Children's Hospital UCLA, Los Angeles, California
Valley Children's Hospital, Madera, California
UCSF Benioff Children's Hospital Oakland, Oakland, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Lucile Packard Children's Hospital Stanford University, Palo Alto, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
UCSF Medical Center-Mission Bay, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
Connecticut Children's Medical Center, Hartford, Connecticut
Yale University, New Haven, Connecticut
Alfred I duPont Hospital for Children, Wilmington, Delaware
Children's National Medical Center, Washington, District of Columbia
Broward Health Medical Center, Fort Lauderdale, Florida
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Nicklaus Children's Hospital, Miami, Florida
AdventHealth Orlando, Orlando, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Saint Mary's Medical Center, West Palm Beach, Florida
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia
Lurie Children's Hospital-Chicago, Chicago, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois
Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Riley Hospital for Children, Indianapolis, Indiana
Blank Children's Hospital, Des Moines, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
Wesley Medical Center, Wichita, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Maine Children's Cancer Program, Scarborough, Maine
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
Sinai Hospital of Baltimore, Baltimore, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Dana-Farber Cancer Institute, Boston, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Bronson Methodist Hospital, Kalamazoo, Michigan
Corewell Health Children's, Royal Oak, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Hackensack University Medical Center, Hackensack, New Jersey
Morristown Medical Center, Morristown, New Jersey
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Saint Joseph's Regional Medical Center, Paterson, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Albany Medical Center, Albany, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
Roswell Park Cancer Institute, Buffalo, New York
NYU Langone Hospital - Long Island, Mineola, New York
The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
University of Rochester, Rochester, New York
New York Medical College, Valhalla, New York
Mission Hospital, Asheville, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Novant Health Presbyterian Medical Center, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
East Carolina University, Greenville, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Broadway Medical Center, Fargo, North Dakota
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Rainbow Babies and Childrens Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Nationwide Children's Hospital, Columbus, Ohio
Dayton Children's Hospital, Dayton, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Legacy Emanuel Children's Hospital, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
The Children's Hospital at TriStar Centennial, Nashville, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Dell Children's Medical Center of Central Texas, Austin, Texas
Driscoll Children's Hospital, Corpus Christi, Texas
Medical City Dallas Hospital, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
El Paso Children's Hospital, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Covenant Children's Hospital, Lubbock, Texas
UMC Cancer Center / UMC Health System, Lubbock, Texas
Children's Hospital of San Antonio, San Antonio, Texas
Methodist Children's Hospital of South Texas, San Antonio, Texas
University of Texas Health Science Center at San Antonio, San Antonio, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Virginia Cancer Center, Charlottesville, Virginia
Naval Medical Center - Portsmouth, Portsmouth, Virginia
Seattle Children's Hospital, Seattle, Washington
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
Children's Hospital of Wisconsin, Milwaukee, Wisconsin
Sydney Children's Hospital, Randwick, New South Wales
The Children's Hospital at Westmead, Westmead, New South Wales
Queensland Children's Hospital, South Brisbane, Queensland
Royal Children's Hospital, Parkville, Victoria
Perth Children's Hospital, Perth, Western Australia
Alberta Children's Hospital, Calgary, Alberta
University of Alberta Hospital, Edmonton, Alberta
British Columbia Children's Hospital, Vancouver, British Columbia
CancerCare Manitoba, Winnipeg, Manitoba
IWK Health Centre, Halifax, Nova Scotia
McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario
Children's Hospital, London, Ontario
Children's Hospital of Eastern Ontario, Ottawa, Ontario
Hospital for Sick Children, Toronto, Ontario
The Montreal Children's Hospital of the MUHC, Montreal, Quebec
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec
Jim Pattison Children's Hospital, Saskatoon, Saskatchewan
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set
Starship Children's Hospital, Grafton, Auckland
Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Recruiting
The purpose of this study is to assess the safety and efficacy of pembrolizumab (MK-3475) combination therapy in participants with metastatic castration resistant prostate cancer (mCRPC). There will be ten cohorts in this study: Cohort A will receive pembrolizumab + olaparib, Cohort B will receive pembrolizumab + docetaxel + prednisone, Cohort C will receive pembrolizumab + enzalutamide, Cohort D will receive pembrolizumab + abiraterone + prednisone Cohort E will receive pembrolizumab+lenvatinib... Read More
The purpose of this study is to assess the safety and efficacy of pembrolizumab (MK-3475) combination therapy in participants with metastatic castration resistant prostate cancer (mCRPC). There will be ten cohorts in this study: Cohort A will receive pembrolizumab + olaparib, Cohort B will receive pembrolizumab + docetaxel + prednisone, Cohort C will receive pembrolizumab + enzalutamide, Cohort D will receive pembrolizumab + abiraterone + prednisone Cohort E will receive pembrolizumab+lenvatinib, Cohort F will receive pembrolizumab+lenvatinib, Cohort G will receive pembrolizumab/vibostolimab coformulation (MK-7684A), Cohort H will receive pembrolizumab/vibostolimab coformulation, Cohort I will receive pembrolizumab+carboplatin+etoposide in Arm 1 and carboplatin+etoposide in Arm 2 and Cohort J will receive belzutifan in Arm1 and Pembrolizumab+belzutifan in Arm 2. Outcome measures will be assessed individually for each cohort. Read Less
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/31/2025
Locations: Call for Information (Investigational Site 0005), Los Angeles, California +26 locations
Call for Information (Investigational Site 0005), Los Angeles, California
Call for Information (Investigational Site 2041), Aurora, Colorado
Call for Information (Investigational Site 2083), Baltimore, Maryland
Call for Information (Investigational Site 2091), Cleveland, Ohio
Call for Information (Investigational Site 2027), Portland, Oregon
Call for Information (Investigational Site 2094), Portland, Oregon
Call for Information (Investigational Site 0008), Pittsburgh, Pennsylvania
Call for Information (Investigational Site 2065), Charleston, South Carolina
Call for Information (Investigational Site 0019), Myrtle Beach, South Carolina
Call for Information (Investigational Site 0016), Seattle, Washington
MSD Australia, North Ryde, Not set
Merck Canada, Kirkland, Quebec
MSD Denmark, Glostrup, Not set
MSD Finland Oy, Espoo, Not set
MSD France, Paris, Not set
MSD Sharp & Dohme GmbH, München, Not set
MSD Ireland (Human Health) Ltd., Dublin, Not set
MSD Italia S.r.l., Rome, Not set
MSD Comercializadora, S. de R.L. de C.V., Mexico City, Not set
Merck Sharp & Dohme BV, Haarlem, Not set
Merck Sharp & Dohme (New Zealand) Ltd.,, Auckland, Not set
MSD Polska Sp. Z o.o., Warsaw, Not set
Merck Sharp and Dohme de Espana S.A., Madrid, Not set
MSD Sweden, Stockholm, Not set
Merck Sharp & Dohme (I.A.) Corp., Taipei, Not set
Merck Sharp & Dohme Ilaclari Ltd. Sti, Istanbul, Not set
Merck Sharp & Dohme Ltd., London, Not set
Conditions: Metastatic Castration-Resistant Prostate Cancer
Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer
Active Not Recruiting
The study will first determine the optimal dose of inupadenant to be given in combination with carboplatin and pemetrexed to patients that progressed after receiving first line anti-PD(L)1 treatment for locally advanced or metastatic non-small cell lung cancer. The efficacy and safety of the combination is then compared to standard of care carboplatin and pemetrexed in the same populations.
The study will first determine the optimal dose of inupadenant to be given in combination with carboplatin and pemetrexed to patients that progressed after receiving first line anti-PD(L)1 treatment for locally advanced or metastatic non-small cell lung cancer. The efficacy and safety of the combination is then compared to standard of care carboplatin and pemetrexed in the same populations. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: Highlands Oncology Group, Fayetteville, Arkansas +20 locations
Highlands Oncology Group, Fayetteville, Arkansas
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Algemeen Ziekenhuis Sint-Lucas, Gent, Not set
Jessa Ziekenhuis, Hasselt, Not set
AZ Delta, Roeselare, Not set
William Osler Health System, Brampton, Ontario
Vseobecna Fakultni Nemocnice, Praha 3, Not set
CHU de Caen, Caen, Not set
Hopital de la Timone Centre d'Essais Précoces en Cancérologie de Marseille (CEPCM), Marseille, Not set
CHU Nantes, Nantes, Not set
Istituto Nazionale dei Tumori, Milano, Not set
Gruppo Humanitas - Istituto Clinico Humanitas, Rozzano, Not set
Hospital Universitari Son Espases, Palma De Mallorca, Illes Balears
Hospital Infanta Cristina (Hospital Universitario de Badajoz), Badajoz, Not set
Hospital Universitario Vall d'Hebron, Barcelona, Not set
Centro Oncologico de Galicia, Coruña, Not set
Althaia Hospital, Manresa, Not set
Complejo Hospitalario Universitario de Ourense, Ourense, Not set
Complejo Hospitalario de Navarra (CHN), Pamplona, Not set
Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set
Centre Hospitalier Universitaire Vaudois, Lausanne, Not set
Conditions: Metastatic NSCLC - Non-Small Cell Lung Cancer, Locally Advanced NSCLC - Non-Small Cell Lung Cancer
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Recruiting
The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want to know if giving intismeran autogene and pembrolizumab after surgery can help prevent the cancer from coming back in people with non-small cell lung cancer (NSCLC) whose tumors did not respond completely to treatment before surgery (neoadjuvant treatment).
The goal of this study is to learn if people who receive intismeran autogene and pembrolizumab after surgery are cancer-free longer than people who receive placebo and pembrolizumab. Researchers want to know if giving intismeran autogene and pembrolizumab after surgery can help prevent the cancer from coming back in people with non-small cell lung cancer (NSCLC) whose tumors did not respond completely to treatment before surgery (neoadjuvant treatment). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: Banner MD Anderson Cancer Center ( Site 0181), Gilbert, Arizona +151 locations
Banner MD Anderson Cancer Center ( Site 0181), Gilbert, Arizona
Providence St. Jude Medical Center ( Site 0106), Fullerton, California
UCSF Medical Center at Mission Bay ( Site 0178), San Francisco, California
UCHealth Memorial Hospital Central ( Site 0125), Colorado Springs, Colorado
Banner MD Anderson Cancer Center at North Colorado Medical Center ( Site 0207), Greeley, Colorado
Beacon Cancer Care ( Site 0127), Post Falls, Idaho
The University of Chicago Medical Center ( Site 0118), Chicago, Illinois
Massachusetts General Hospital ( Site 0136), Boston, Massachusetts
Dana Farber Cancer Hospital ( Site 0155), Boston, Massachusetts
Ellis Fischel Cancer Center ( Site 0133), Columbia, Missouri
Lake Regional Hospital-Cancer Center ( Site 0123), Osage Beach, Missouri
Montefiore Medical Center ( Site 0160), Bronx, New York
Roswell Park Cancer Institute ( Site 0184), Buffalo, New York
Hematology-Oncology Associates of CNY ( Site 0164), East Syracuse, New York
Icahn School of Medicine at Mount Sinai ( Site 0116), New York, New York
Memorial Sloan Kettering Cancer Center ( Site 0137), New York, New York
SUNY Upstate Cancer Center ( Site 0140), Syracuse, New York
Westchester Medical Center ( Site 0196), Valhalla, New York
University of Cincinnati Medical Center ( Site 0119), Cincinnati, Ohio
St. Lukes Hospital and Health Network ( Site 0186), Bethlehem, Pennsylvania
Thompson Cancer Survival Center ( Site 0168), Knoxville, Tennessee
MD Anderson Cancer Center ( Site 0150), Houston, Texas
Memorial Hermann Cancer Center ( Site 0172), Houston, Texas
O'Quinn Medical Tower at McNair Campus ( Site 0131), Houston, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0148), Tyler, Texas
Swedish Cancer Institute ( Site 0143), Seattle, Washington
Virginia Mason Franciscan Health - St. Michael Cancer Center ( Site 0192), Silverdale, Washington
CEMIC ( Site 2454), Caba., Buenos Aires
Fundacion Intecnus ( Site 2456), San Carlos de Bariloche, Rio Negro
Centro Médico IPAM ( Site 2452), Rosario, Santa Fe
Instituto Medico Especializado Alexander Fleming ( Site 2457), Buenos Aires, Not set
Instituto Oncologico de Cordoba -IONC ( Site 2455), Cordoba, Not set
Calvary Mater Newcastle ( Site 2106), Waratah, New South Wales
Tasman Oncology Research ( Site 2104), Southport, Queensland
Princess Alexandra Hospital ( Site 2102), Wooloongabba, Queensland
Grampians Health ( Site 2101), Ballarat, Victoria
One Clinical Research ( Site 2103), Nedlands, Western Australia
Cliniques Universitaires Saint-Luc ( Site 1203), Bruxelles, Bruxelles-Capitale, Region De
Jessa Ziekenhuis ( Site 1204), Hasselt, Limburg
UZ Gent ( Site 1201), Gent, Oost-Vlaanderen
CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA ( Site 2502), Fortaleza, Ceara
Liga Norte Riograndense Contra o Cancer ( Site 2513), Natal, Rio Grande Do Norte
Hospital Tacchini ( Site 2506), Bento Goncalves, Rio Grande Do Sul
Hospital de Clínicas de Passo Fundo ( Site 2504), Passo Fundo, Rio Grande Do Sul
Hospital Moinhos de Vento ( Site 2510), Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora Da Conceicao ( Site 2512), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 2507), Santa Cruz do Sul, Rio Grande Do Sul
Hospital de Amor - Barretos ( Site 2511), Barretos, Sao Paulo
Instituto Nacional de Câncer - INCA ( Site 2501), Rio de Janeiro, Not set
MBAL Uni Hospital ( Site 1253), Panagyurishte, Pazardzhik
MHAT - Heart and Brain ( Site 1252), Pleven, Not set
Queen Elizabeth II Health Sciences Centre ( Site 1101), Halifax, Nova Scotia
Hamilton Health Sciences - Juravinski Site ( Site 1104), Hamilton, Ontario
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 1105), Kingston, Ontario
Lakeridge Health ( Site 1107), Oshawa, Ontario
McGill University Health Centre ( Site 1103), Montréal, Quebec
IUCPQ ( Site 1112), Québec, Quebec
FALP ( Site 2551), Santiago., Region M. De Santiago
Orlandi Oncologia ( Site 2555), Santiago, Region M. De Santiago
Clínica RedSalud Vitacura ( Site 2556), Santiago, Region M. De Santiago
Bradfordhill ( Site 2552), Santiago, Region M. De Santiago
ONCOCENTRO APYS ( Site 2554), Viña del Mar, Valparaiso
IMAT S.A.S ( Site 2602), Monteria, Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 2603), Bogota, Distrito Capital De Bogota
Hospital Universitario San Ignacio ( Site 2610), Bogota, Distrito Capital De Bogota
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 2604), Bogota, Distrito Capital De Bogota
Oncologos del Occidente ( Site 2608), Pereira, Risaralda
Fundacion Valle del Lili- CIC ( Site 2601), Cali, Valle Del Cauca
Oulun yliopistollinen sairaala ( Site 1301), Oulu, Pohjois-Pohjanmaa
Turku University Hospital ( Site 1303), Turku, Varsinais-Suomi
CHU Besançon ( Site 1358), Besancon, Franche-Comte
Institut De Cancerologie De L Ouest ( Site 1357), Saint Herblain, Loire-Atlantique
CENTRE LEON BERARD ( Site 1351), Lyon CEDEX 08, Rhone
Marienhaus Klinikum Mainz ( Site 1403), Mainz, Rheinland-Pfalz
UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 1452), Patras, Achaia
Errikos Dunant Hospital Center ( Site 1457), Athens, Attiki
THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 1451), Athens, Attiki
Metropolitan Hospital ( Site 1459), Athens, Attiki
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1460), Chaidari, Attiki
University General Hospital of Herakleion ( Site 1458), Herakleion., Irakleio
University General Hospital of Larissa-Oncology Clinic ( Site 1453), Larissa, Thessalia
Papageorgiou General Hospital of Thessaloniki ( Site 1454), Thessaloniki, Not set
Petz Aladár Megyei Oktató Kórház ( Site 1502), Gyor, Gyor-Moson-Sopron
Debreceni Egyetem Altalanos Orvostudomanyi Kar Tudogyogyaszati Tanszek ( Site 1508), Debrecen, Hajdu-Bihar
Mátrai Gyógyintézet ( Site 1504), Mátraháza, Heves
Reformatus Pulmonologiai Centrum-Onkopulmonologiai Jarobeteg Centrum ( Site 1505), Törökbálint, Pest
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1507), Kaposvár, Somogy
Orszagos Koranyi Pulmonologiai Intezet ( Site 1501), Budapest, Not set
Rambam Health Care Campus ( Site 1603), Haifa, Not set
Shaare Zedek Medical Center ( Site 1601), Jerusalem, Not set
Hadassah Medical Center ( Site 1605), Jerusalem, Not set
Sheba Medical Center ( Site 1602), Ramat Gan, Not set
Hospital of the University of Occupational and Environmental Health, Japan ( Site 1166), Kitakyushu, Fukuoka
St. Marianna University Hospital ( Site 1159), Kawasaki, Kanagawa
Kindai University Hospital ( Site 1162), Osakasayama, Osaka
National Cancer Center Hospital ( Site 1156), Chuo, Tokyo
Tokyo Medical University Hospital ( Site 1157), Shinjuku, Tokyo
Chiba University Hospital ( Site 1154), Chiba, Not set
National Hospital Organization Kyushu Cancer Center ( Site 1167), Fukuoka, Not set
Fukushima Medical University Hospital ( Site 1151), Fukushima, Not set
Hiroshima University Hospital ( Site 1165), Hiroshima, Not set
Wakayama Medical University Hospital ( Site 1163), Wakayama, Not set
National Cancer Center ( Site 2305), Goyang-si, Kyonggi-do
The Catholic University of Korea St. Vincent s Hospital ( Site 2301), Suwonsi, Kyonggi-do
Ajou University Hospital ( Site 2306), Suwon, Kyonggi-do
Seoul National University Hospital ( Site 2303), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 2302), Seoul, Not set
Samsung Medical Center ( Site 2304), Seoul, Not set
Seoul St. Mary's Hospital ( Site 2307), Seoul, Not set
Medisch Centrum Leeuwarden ( Site 1702), Leeuwarden, Fryslan
Radboudumc ( Site 1706), Nijmegen, Gelderland
Dunedin Hospital ( Site 2202), Dunedin, Otago
Aliada ( Site 2753), Lima, Not set
Detecta Clínica ( Site 2751), Lima, Not set
Krakowski Szpital Specjalistyczny im. Jana Pawla II ( Site 1756), Krakow, Malopolskie
Instytut Gruźlicy i Chorób Płuc w Warszawie ( Site 1764), Warszawa, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1759), Przemysl, Podkarpackie
Uniwersyteckie Centrum Kliniczne ( Site 1758), Gdansk, Pomorskie
Swietokrzyskie Centrum Onkologii. ( Site 1754), Kielce, Swietokrzyskie
Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie ( Site 1760), Olsztyn, Warminsko-mazurskie
Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 1763), Poznan, Wielkopolskie
Centrul Medical Medicover Victoria ( Site 1802), Bucharest, Bucuresti
Institutul Regional de Oncologie ( Site 1804), Iasi, Not set
National Cancer Centre Singapore ( Site 2251), Singapore, Central Singapore
Tan Tock Seng Hospital ( Site 2252), Singapore, Central Singapore
Hospital Clinic de Barcelona ( Site 1919), Barcelona, Cataluna
Complejo Hospitalario Universitario A Coruna ( Site 1916), A Coruña, La Coruna
Hospital Universitario Quiron Madrid ( Site 1913), Pozuelo de Alarcon, Madrid
Hospital Insular de Gran Canaria ( Site 1911), Canarias, Not set
Hospital General Universitario Gregorio Maranon ( Site 1912), Madrid, Not set
Hospital Quiron Malaga ( Site 1914), Malaga, Not set
Karolinska Universitetssjukhuset Solna ( Site 1951), Stockholm, Stockholms Lan
Chung Shan Medical University Hospital ( Site 2351), Taichung, Not set
China Medical University Hospital ( Site 2358), Taichung, Not set
National Cheng Kung University Hospital ( Site 2354), Tainan, Not set
National Taiwan University Cancer Center (NTUCC) ( Site 2360), Taipei, Not set
Mackay Memorial Hospital ( Site 2355), Taipei, Not set
Taipei Medical University Hospital ( Site 2352), Taipei, Not set
Koo Foundation Sun Yat-Sen Cancer Center ( Site 2359), Taipei, Not set
Taipei Veterans General Hospital ( Site 2357), Taipei, Not set
Chang Gung Memorial Hospital ( Site 2361), Taoyuan, Not set
Hacettepe Universite Hastaneleri ( Site 2001), Sıhhiye, Ankara
Namık Kemal University Medical Faculty ( Site 2007), Tekirdag, Tekirdas
Ankara Bilkent Sehir Hastanesi ( Site 2002), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi ( Site 2003), Istanbul, Not set
Bristol Haematology and Oncology Centre ( Site 2072), Bristol, Bristol, City Of
St Bartholomews Hospital ( Site 2052), London, London, City Of
Royal Free Hospital ( Site 2074), London, London, City Of
Guys Hospital ( Site 2057), London, London, City Of
Nottingham City Hospital ( Site 2058), Nottingham, Nottinghamshire
St James University Hospital ( Site 2055), Leeds, Not set
The Clatterbridge Cancer Centre ( Site 2069), Wirral, Not set
Conditions: Carcinoma, Non-Small-Cell Lung
AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).
Recruiting
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted thoracic tumors. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced MTAP-deleted thoracic... Read More
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted thoracic tumors. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced MTAP-deleted thoracic tumors. Read Less
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/30/2025
Locations: Comprehensive Blood and Cancer Center, Bakersfield, California +78 locations
Comprehensive Blood and Cancer Center, Bakersfield, California
City of Hope National Medical Center, Duarte, California
Translational Research in Oncology US Inc, Trio Central Pharmacy, Los Angeles, California
University of California Irvine, Orange, California
University of California Los Angeles, Santa Monica, California
Rocky Mountain Cancer Centers, Denver, Colorado
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut
HealthPartners Institute, Saint Paul, Minnesota
Saint Lukes Hospital of Kansas City, Kansas City, Missouri
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
Roswell Park Cancer Institute, Buffalo, New York
New York University Grossman School of Medicine, New York, New York
Perlmutter Cancer Center at New York University Langone Hospital----Long Island, New York, New York
Upstate University Hospital, Syracuse, New York
Hightower Clinical, Oklahoma City, Oklahoma
Fox Chase Cancer Center, Philadelphia, Pennsylvania
University of Tennessee Medical Center Knoxville, Knoxville, Tennessee
United States Oncology Regulatory Affairs Corporate Office, Nashville, Tennessee
Texas Oncology - Dallas Fort Worth, Dallas, Texas
US Oncology Research Investigational Products Center, Dallas, Texas
Oncology Consultants Cancer Center, Houston, Texas
Texas Oncology Northeast Texas, Tyler, Texas
Virginia Cancer Specialists PC, Fairfax, Virginia
Northwest Medical Specialties, PLLC, Tacoma, Washington
Instituto Argentino de Diagnóstico y Tratamiento, Ciudad Automona De Buenos Aires, Buenos Aires
Cemic, Ciudad Autonoma Buenos Aires, Not set
Orange Health Service, Orange, New South Wales
The Queen Elizabeth Hospital, Woodville South, South Australia
Medizinische Universitaet Graz, Graz, Not set
Medizinische Universitaet Innsbruck, Innsbruck, Not set
Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, Not set
Oncosite Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, Rio Grande Do Sul
Beneficencia Portuguesa de Sao Paulo - Bp, Sao Paulo, São Paulo
Fund Fac Reg Med Sao Jose Rio Preto, São José do Rio Preto, São Paulo
Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp, São Paulo, Not set
Princess Margaret Cancer Centre, Toronto, Ontario
Mengchao Hepatobiliary hospital of Fujian Medical University, Fuzhou, Fujian
Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei
Jilin Cancer Hospital, Changchun, Jilin
West China Hospital of Sichuan University, Chengdu, Sichuan
Beijing Cancer Hospital, Beijing, Not set
Institut Bergonie, Bordeaux, Not set
Hopital de la Timone, Marseille, Not set
Institut de Cancerologie de l Ouest Rene Gauducheau, Saint Herblain, Not set
Gustave Roussy, Villejuif, Not set
Universitaetsklinikum Essen, Essen, Not set
Thoraxklinik Heidelberg, Heidelberg, Not set
Universitaetsklinikum Wuerzburg, Wuerzburg, Not set
Alexandra Hospital, Athens, Not set
Saint Luke Hospital, Thessaloniki, Not set
General Hospital Of Thessaloniki Papageorgiou, Thessaloniki, Not set
Queen Mary Hospital, The University of Hong Kong, Hong Kong, Not set
Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Alessandria, Not set
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Not set
IRCCS Istituto Clinico Humanitas, Rozzano (MI), Not set
Centro Ricerche Cliniche Di Verona Societa responsabilita limitata, Verona, Not set
Aichi Cancer Center, Nagoya-shi, Aichi
National Cancer Center Hospital East, Kashiwa-shi, Chiba
Shizuoka Cancer Center, Sunto-gun, Shizuoka
Wakayama Medical University Hospital, Wakayama-shi, Wakayama
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Radboud Universitair Medisch Centrum, Nijmegen, Not set
Uniwersyteckie Centrum Kliniczne, Gdansk, Not set
Narodowy Instytut Onkologii im Marii Slodowskiej Curie Panstwowy Instytut Badawczy, Gliwice, Not set
Futuremeds spolka z ograniczona odpowiedzialnoscia, Kraków, Not set
Instytut Centrum Zdrowia Matki Polki, Lodz, Not set
Centrum Medyczne Hope Clinic Sebastian Szklener, Lublin, Not set
Hospital Universitari Vall d Hebron, Barcelona, Cataluña
Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña
Hospital Universitario 12 de Octubre, Madrid, Not set
National Cheng Kung University Hospital, Tainan, Not set
Taipei Veterans General Hospital, Taipei, Not set
Adana Sehir Egitim ve Arastirma Hastanesi, Adana, Not set
Hacettepe Universitesi Tip Fakultesi Hastanesi, Ankara, Not set
Ankara Bilkent Sehir Hastanesi, Ankara, Not set
Conditions: Thoracic Tumors, Non-small Cell Lung Cancer
Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006)
Active Not Recruiting
The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, versus (vs) pembrolizumab plus maintenance pemetrexed for the treatment of non-squamous NSCLC. The study's 2 primary hypotheses are: 1. Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance pemetrexed with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent clinical review (BICR) and 2. Pembrolizu... Read More
The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, versus (vs) pembrolizumab plus maintenance pemetrexed for the treatment of non-squamous NSCLC. The study's 2 primary hypotheses are: 1. Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance pemetrexed with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent clinical review (BICR) and 2. Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance pemetrexed with respect to overall survival (OS). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: Alabama Oncology Bruno Cancer Center ( Site 0001), Birmingham, Alabama +177 locations
Alabama Oncology Bruno Cancer Center ( Site 0001), Birmingham, Alabama
Northwest Alabama Cancer Center, PC ( Site 0002), Muscle Shoals, Alabama
Disney Family Cancer Center ( Site 0005), Burbank, California
Boca Raton Regional Hospital ( Site 0018), Boca Raton, Florida
Mid-Florida Cancer Centers ( Site 0022), Orange City, Florida
Moffitt Cancer Center ( Site 0024), Tampa, Florida
Columbus Regional Research Institute ( Site 0098), Columbus, Georgia
Mount Sinai Hospital Medical Center ( Site 0032), Chicago, Illinois
Oncology of Northshore ( Site 0033), Rolling Meadows, Illinois
Methodists Hospitals/Premier Oncology Hematology Associates ( Site 0036), Merrillville, Indiana
Medstar Good Samaritan Hospital ( Site 0040), Baltimore, Maryland
Barbara Ann Karmanos Cancer Institute ( Site 0041), Detroit, Michigan
Hattiesburg Clinic ( Site 0045), Hattiesburg, Mississippi
Frontier Oncology ( Site 0080), Billings, Montana
Bozeman Health Deaconness Cancer Center ( Site 0046), Bozeman, Montana
Waverly Hematology Oncology ( Site 0081), Cary, North Carolina
Thompson Cancer Survival Center ( Site 2812), Knoxville, Tennessee
University of Tennessee Medical Center Knoxville ( Site 0060), Knoxville, Tennessee
Renovatio Clinical ( Site 0062), The Woodlands, Texas
Cancer Care Northwest ( Site 0071), Spokane Valley, Washington
Hospital Italiano Regional del Sur ( Site 0509), Bahia Blanca, Buenos Aires
Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 0511), Ciudad Autonoma de Buenos Aires, Buenos Aires
Hospital Britanico de Buenos Aires ( Site 0500), Ciudad autónoma de Buenos Aires, Buenos Aires
Instituto Medico Rio Cuarto ( Site 0501), Rio Cuarto., Cordoba
Centro Oncológico de Rosario ( Site 0507), Rosario, Santa Fe
Centro Medico San Roque ( Site 0506), San Miguel de Tucuman, Tucuman
Clínica Universitaria Reina Fabiola ( Site 0505), Cordoba, Not set
Sanatorio Privado San Geronimo S.R.L ( Site 0510), Santa Fe, Not set
Liverpool Hospital ( Site 1201), Liverpool, New South Wales
Southern Medical Day Care Centre ( Site 1200), Wollongong, New South Wales
Townsville General Hospital ( Site 1202), Townsville, Queensland
Monash Cancer Centre ( Site 1205), Clayton, Victoria
Ordensklinikum Linz GmbH Elisabethinen ( Site 1307), Linz, Oberosterreich
Klinikum Wels-Grieskirchen ( Site 1304), Wels, Oberosterreich
Innsbruck LKH ( Site 1302), Innsbruck, Tirol
Social Medical Center - Otto Wagner Hospital ( Site 1301), Vienna, Wien
Krankenhaus Nord - Klinik Floridsdorf ( Site 1300), Wien, Not set
Hospital Sao Rafael ( Site 0212), Salvador, Bahia
Instituto do Cancer do Ceara ( Site 0201), Fortaleza, Ceara
Oncologica do Brasil ( Site 0210), Belem, Para
Hospital Tacchini ( Site 0208), Bento Goncalves, Rio Grande Do Sul
Irmandade da Santa Casa de Misericordia de Porto Alegre ( Site 0209), Porto Alegre, Rio Grande Do Sul
Saint Gallen Instituto de Oncologia ( Site 0206), Santa Cruz do Sul, Rio Grande Do Sul
YNOVA Pesquisa Clinica ( Site 0215), Florianopolis, Santa Catarina
Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 0202), Itajai, Santa Catarina
Centro de Hematologia e Oncologia ( Site 0205), Joinville, Santa Catarina
Hospital de Base de Sao Jose de Rio Preto ( Site 0204), Sao Jose Rio Preto, Sao Paulo
Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0203), Rio de Janeiro, Not set
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0200), Sao Paulo, Not set
BP - A Beneficencia Portuguesa de São Paulo-Medical Oncology ( Site 0214), Sao Paulo, Not set
Hospital Paulistano - Amil Clinical Research ( Site 0207), Sao Paulo, Not set
Lions Gate Hospital ( Site 0106), North Vancouver, British Columbia
BC Cancer - Victoria ( Site 0109), Victoria, British Columbia
Queen Elizabeth II Health Sciences Centre ( Site 0107), Halifax, Nova Scotia
Waterloo Regional Health Network (WRHN) ( Site 0117), Kitchener, Ontario
Stronach Regional Cancer Centre ( Site 0101), Newmarket, Ontario
Health Sciences North Research Institute ( Site 0115), Sudbury, Ontario
CISSS de la Monteregie-Centre ( Site 0114), Greenfield Park, Quebec
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0105), Montreal, Quebec
CIUSSS Ouest de l Ile - St-Mary s Hospital ( Site 0110), Montreal, Quebec
Centre de Sante et des Services Sociaux de Rimouski-Neigette ( Site 0104), Rimouski, Quebec
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0103), Sherbrooke, Quebec
Fundacion Colombiana de Cancerologia Clinica Vida ( Site 0604), Medellin, Antioquia
Clinica de la Costa S.A.S. ( Site 0608), Barranquilla, Atlantico
Administradora Country S.A. ( Site 0603), Bogota, Distrito Capital De Bogota
Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 0601), Bogotá, Distrito Capital De Bogota
Institut De Cancerologie De Lorraine ( Site 1409), Vandoeuvre les Nancy, Ain
Centre Hospitalier De Chauny ( Site 1411), Chauny, Aisne
CHU Caen ( Site 1406), Caen, Calvados
CHU Angers ( Site 1405), Angers, Maine-et-Loire
Hopital Robert Schuman ( Site 1402), Vantoux, Moselle
Centre Jean Perrin ( Site 1407), Clermont Ferrand, Puy-de-Dome
Centre Hospitalier de Pau ( Site 1412), Pau, Pyrenees-Atlantiques
CHU de Rouen ( Site 1403), Rouen, Seine-Maritime
Hopital d'Instruction des Armees Begin ( Site 1413), Saint-Mande, Val-de-Marne
Studienzentrum Aschaffenburg ( Site 1525), Aschaffenburg, Bayern
Klinikum Bogenhausen Staedt. Klinikum Muenchen GmbH ( Site 1523), Muenchen, Bayern
Klinikum der LMU ( Site 1500), Munich, Bayern
Universitaetsklinikum Regensburg ( Site 1512), Regensburg, Bayern
Klinikum Wuerzburg Mitte gGmbH ( Site 1509), Wuerzburg, Bayern
Universitaetsklinikum Frankfurt ( Site 1513), Frankfurt, Hessen
Pneumologische Lehrklinik Universitaet Goettingen ( Site 1501), Immenhausen, Hessen
Universitaetsmedizin Goettingen ( Site 1507), Goettingen, Niedersachsen
Universitaetsklinikum Bonn ( Site 1524), Bonn, Nordrhein-Westfalen
Kliniken Essen Mitte ( Site 1517), Essen, Nordrhein-Westfalen
InVo-Institut fuer Versorgungsforschung in der Onkologie ( Site 1514), Koblenz, Rheinland-Pfalz
Helios Klinikum Erfurt GmbH ( Site 1502), Erfurt, Thuringen
Katholisches Marienkrankenhaus gGmbH ( Site 1522), Hamburg, Not set
National Hospital Organization Nagoya Medical Center ( Site 0806), Nagoya, Aichi
Aichi Cancer Center ( Site 0803), Nagoya, Aichi
National Cancer Center Hospital East ( Site 0801), Kashiwa, Chiba
Kanazawa University Hospital ( Site 0811), Kanazawa, Ishikawa
Kanagawa Cancer Center ( Site 0807), Yokohama, Kanagawa
Sendai Kousei Hospital ( Site 0812), Sendai, Miyagi
Kansai Medical University Hospital ( Site 0804), Hirakata, Osaka
National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0813), Sakai, Osaka
Shizuoka Cancer Center ( Site 0802), Suntogun, Shizuoka
National Hospital Organization Kyushu Medical Center ( Site 0805), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 0808), Niigata, Not set
Okayama University Hospital ( Site 0810), Okayama, Not set
Osaka International Cancer Institute ( Site 0809), Osaka, Not set
Cancer Institute Hospital of JFCR ( Site 0800), Tokyo, Not set
Chungbuk National University Hospital ( Site 1002), Cheongju si, Chungbuk
National Cancer Center ( Site 1006), Goyang-si, Kyonggi-do
The Catholic University of Korea St. Vincent s Hospital ( Site 1003), Suwon, Kyonggi-do
Ajou University Hospital ( Site 1004), Suwon, Kyonggi-do
Gyeongsang National University Hospital ( Site 1005), Jinju, Kyongsangnam-do
Asan Medical Center ( Site 1007), Songpa-gu, Seoul
Seoul National University Hospital ( Site 1000), Seoul, Not set
Korea University Guro Hospital ( Site 1008), Seoul, Not set
MidCentral DHB Palmerston North Hospital ( Site 1102), Palmerston North, Manawatu-Wanganui
Capital & Coast District Health Board - Wellington Hospital ( Site 1101), Wellington, Not set
Wielospecjalistyczny Szpital SPZOZ w Zgorzelcu ( Site 2404), Zgorzelec, Dolnoslaskie
Krakowski Szpital Specjalistyczny im Jana Pawla II ( Site 2420), Krakow, Malopolskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 2418), Warszawa, Mazowieckie
Szpital Rejonowy im. dr Jozefa Rostka ( Site 2402), Raciborz, Slaskie
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie ( Site 2417), Olsztyn, Warminsko-mazurskie
Przychodnia Lekarska Komed ( Site 2416), Konin, Wielkopolskie
MED-POLONIA Sp. z o.o. ( Site 2419), Poznan, Wielkopolskie
MEMORIAL HEALTHCARE INTERNATIONAL S.R.L. ( Site 2502), Bucharest, Bucuresti
Cardiomed SRL Cluj-Napoca ( Site 2504), Cluj Napoca, Cluj
S.C. Radiotherapy Center Cluj S.R.L ( Site 2507), Cluj-Napoca, Cluj
Ovidius Clinical Hospital OCH ( Site 2501), Ovidiu, Constanta
S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 2508), Craiova, Dolj
Policlinica Oncomed SRL ( Site 2505), Timisoara, Timis
Spitalul PDR Medlife ( Site 2509), Brasov, Not set
Moscow Regional Oncological Dispensary ( Site 2028), Balashikha, Moskovskaya Oblast
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 2000), Moscow, Moskva
First Moscow State Medical University n.a. I.M.Sechenov ( Site 2024), Moscow, Moskva
Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2009), Moscow, Moskva
FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 2006), Moscow, Moskva
Nizhniy Novgorod Region Oncology Dispensary ( Site 2026), Nizhniy Novgorod, Nizhegorodskaya Oblast
Budgetary Healthcare Institution of Omsk Region Clinical Oncology Dispensary-Chemotherapy #1 ( Site 2010), Omsk, Omskaya Oblast
SBHI Samara Regional Clinical Oncology Dispensary ( Site 2016), Samara, Samarskaya Oblast
SBHI Leningrad Regional Clinical Hospital ( Site 2002), Saint Petersburg, Sankt-Peterburg
SPb Central Clinical Railway Hospital ( Site 2003), Saint Petersburg, Sankt-Peterburg
National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 2004), Saint Petersburg, Sankt-Peterburg
SPb SBHI City Clinical Oncological Dispensary ( Site 2001), Saint Petersburg, Sankt-Peterburg
Republican Clinical Oncology Dispensary of Tatarstan MoH named after professor M.Z. Sigal ( Site 2021), Kazan, Tatarstan, Respublika
Hospital Universitario Quiron Madrid ( Site 1701), Pozuelo de Alarcon, Madrid
Hospital Clinico Universitario de Valencia ( Site 1706), Valencia, Valenciana, Comunitat
Hospital del Mar ( Site 1702), Barcelona, Not set
Hospital Universitario Nuestra Senora de Valme ( Site 1703), Sevilla, Not set
Hospital Clinico Lozano Blesa ( Site 1700), Zaragoza, Not set
Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0907), Kaohsiung, Not set
China Medical University Hospital ( Site 0904), Taichung, Not set
National Cheng Kung University Hospital ( Site 0905), Tainan, Not set
National Taiwan University Hospital ( Site 0900), Taipei, Not set
Mackay Memorial Hospital ( Site 0902), Taipei, Not set
Chang Gung Medical Foundation.Linkou Branch ( Site 0903), Taoyuan, Not set
Namik Kemal Universitesi Tip Fakultesi ( Site 2100), Tekirdag, Tekirdas
Baskent Unv. Adana Uyg. ve Arast. Hastanesi ( Site 2101), Adana, Not set
Gazi Universitesi Tip Fakultesi ( Site 2104), Ankara, Not set
Ankara Bilkent Sehir Hastanesi ( Site 2105), Ankara, Not set
Bezmialem Vakif Univ. Tıp Fakultesi Hastanesi Tibbi Onkoloji Bolumu ( Site 2107), Istanbul, Not set
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 2103), Istanbul, Not set
Ege Universitesi Tip Fakultesi ( Site 2109), Izmir, Not set
Erciyes Universitesi Tip Fakultesi ( Site 2108), Kayseri, Not set
Ondokuz Mayıs Universitesi-Oncology department ( Site 2106), Samsun, Not set
Cherkasy Regional Oncology Dispensary ( Site 2211), Cherkasy, Cherkaska Oblast
Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council ( Site 2201), Dnipro, Dnipropetrovska Oblast
MI Precarpathian Clinical Oncology Center ( Site 2204), Ivano-Frankivsk, Ivano-Frankivska Oblast
Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 2212), Kharkiv, Kharkivska Oblast
CNPE "Regional Center of Oncology"-Thoracic organs ( Site 2205), Kharkiv, Kharkivska Oblast
PP PPC Acinus Medical and Diagnostic Centre ( Site 2209), Kropyvnitskiy, Kirovohradska Oblast
Medical Center Asklepion LLC ( Site 2234), Khodosivka, Kyivska Oblast
Medical Center Verum ( Site 2230), Kyiv, Kyivska Oblast
Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 2213), Kyiv, Kyivska Oblast
MI Odessa Regional Oncological Centre ( Site 2208), Odesa, Odeska Oblast
Central City Clinical Hospital ( Site 2207), Uzhgorod, Zakarpatska Oblast
Kyiv City Clinical Oncology Centre ( Site 2210), Kyiv, Not set
Barts Health NHS Trust - St Bartholomew s Hospital ( Site 1923), London, London, City Of
Chelsea and Westminster Hospital ( Site 1901), London, London, City Of
West Suffolk Hospitals NHS Trust ( Site 1919), Bury Saint Edmunds, Suffolk
Singleton Hospital ( Site 1909), Swansea, Wales
Colchester General Hospital ( Site 1911), Colchester, Worcestershire
Birmingham Heartlands Hospital ( Site 1910), Birmingham, Not set
Western General Hospital, Edinburgh ( Site 1924), Edinburg, Not set
Conditions: Carcinoma, Nonsquamous Non-small-cell Lung
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer
Active Not Recruiting
This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, an... Read More
This phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression is superior to induction with pembrolizumab, pemetrexed and carboplatin followed by pembrolizumab and pemetrexed maintenance in treating patients with stage IV non-squamous non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as pemetrexed, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. It is not yet known whether giving first-line pembrolizumab followed by pemetrexed and carboplatin with or without pembrolizumab works better in treating patients with non-squamous non-small cell cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: University of South Alabama Mitchell Cancer Institute, Mobile, Alabama +1098 locations
University of South Alabama Mitchell Cancer Institute, Mobile, Alabama
Anchorage Associates in Radiation Medicine, Anchorage, Alaska
Anchorage Radiation Therapy Center, Anchorage, Alaska
Alaska Breast Care and Surgery LLC, Anchorage, Alaska
Alaska Oncology and Hematology LLC, Anchorage, Alaska
Alaska Women's Cancer Care, Anchorage, Alaska
Anchorage Oncology Centre, Anchorage, Alaska
Katmai Oncology Group, Anchorage, Alaska
Providence Alaska Medical Center, Anchorage, Alaska
Fairbanks Memorial Hospital, Fairbanks, Alaska
Kingman Regional Medical Center, Kingman, Arizona
Cancer Center at Saint Joseph's, Phoenix, Arizona
University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
Mercy Hospital Fort Smith, Fort Smith, Arkansas
CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro, Arkansas
CARTI Cancer Center, Little Rock, Arkansas
Kaiser Permanente-Anaheim, Anaheim, California
Kaiser Permanente-Deer Valley Medical Center, Antioch, California
Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California
PCR Oncology, Arroyo Grande, California
Sutter Auburn Faith Hospital, Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California
Kaiser Permanente-Baldwin Park, Baldwin Park, California
Kaiser Permanente-Bellflower, Bellflower, California
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Tower Cancer Research Foundation, Beverly Hills, California
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California
Mills-Peninsula Medical Center, Burlingame, California
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California
Mercy Cancer Center - Carmichael, Carmichael, California
Mercy San Juan Medical Center, Carmichael, California
Eden Hospital Medical Center, Castro Valley, California
Sutter Davis Hospital, Davis, California
Kaiser Permanente Dublin, Dublin, California
21st Century Oncology - El Segundo, El Segundo, California
Mercy Cancer Center - Elk Grove, Elk Grove, California
Kaiser Permanente-Fontana, Fontana, California
Kaiser Permanente-Fremont, Fremont, California
Palo Alto Medical Foundation-Fremont, Fremont, California
Fresno Cancer Center, Fresno, California
Kaiser Permanente-Fresno, Fresno, California
Kaiser Permanente South Bay, Harbor City, California
Kaiser Permanente-Irvine, Irvine, California
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
Kaiser Permanente West Los Angeles, Los Angeles, California
Cedars Sinai Medical Center, Los Angeles, California
Fremont - Rideout Cancer Center, Marysville, California
Mercy Cancer Center, Merced, California
Memorial Medical Center, Modesto, California
Kaiser Permanente-Modesto, Modesto, California
Palo Alto Medical Foundation-Camino Division, Mountain View, California
Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California
Sutter Cancer Research Consortium, Novato, California
Kaiser Permanente Oakland-Broadway, Oakland, California
Kaiser Permanente-Oakland, Oakland, California
Kaiser Permanente-Ontario, Ontario, California
Saint Joseph Hospital - Orange, Orange, California
Palo Alto Medical Foundation Health Care, Palo Alto, California
VA Palo Alto Health Care System, Palo Alto, California
Kaiser Permanente - Panorama City, Panorama City, California
Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California
Kaiser Permanente- Marshall Medical Offices, Redwood City, California
Kaiser Permanente-Redwood City, Redwood City, California
Kaiser Permanente-Richmond, Richmond, California
Kaiser Permanente-Riverside, Riverside, California
Mercy Cancer Center - Rocklin, Rocklin, California
Rohnert Park Cancer Center, Rohnert Park, California
Kaiser Permanente-Roseville, Roseville, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Roseville Medical Center, Roseville, California
The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California
Kaiser Permanente Downtown Commons, Sacramento, California
Mercy Cancer Center - Sacramento, Sacramento, California
Sutter Medical Center Sacramento, Sacramento, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
Kaiser Permanente-South Sacramento, Sacramento, California
South Sacramento Cancer Center, Sacramento, California
Saint Helena Hospital, Saint Helena, California
Kaiser Permanente-San Diego Mission, San Diego, California
Kaiser Permanente-San Diego Zion, San Diego, California
Zuckerberg San Francisco General Hospital, San Francisco, California
California Pacific Medical Center-Pacific Campus, San Francisco, California
Kaiser Permanente-San Francisco, San Francisco, California
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California
Kaiser Permanente San Leandro, San Leandro, California
Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California
Kaiser Permanente-San Marcos, San Marcos, California
Kaiser San Rafael-Gallinas, San Rafael, California
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California
Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California
Mission Hope Medical Oncology - Santa Maria, Santa Maria, California
Kaiser Permanente-Santa Rosa, Santa Rosa, California
Sutter Pacific Medical Foundation, Santa Rosa, California
Kaiser Permanente Cancer Treatment Center, South San Francisco, California
Kaiser Permanente-South San Francisco, South San Francisco, California
Kaiser Permanente-Stockton, Stockton, California
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California
Cedars-Sinai Cancer - Tarzana, Tarzana, California
Torrance Memorial Physician Network - Cancer Care, Torrance, California
Torrance Memorial Medical Center, Torrance, California
Kaiser Permanente Medical Center-Vacaville, Vacaville, California
Kaiser Permanente-Vallejo, Vallejo, California
Sutter Solano Medical Center/Cancer Center, Vallejo, California
Kaiser Permanente-Walnut Creek, Walnut Creek, California
Kaiser Permanente-Woodland Hills, Woodland Hills, California
Woodland Memorial Hospital, Woodland, California
Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado
The Medical Center of Aurora, Aurora, Colorado
UCHealth University of Colorado Hospital, Aurora, Colorado
Boulder Community Foothills Hospital, Boulder, Colorado
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado
Rocky Mountain Cancer Centers - Centennial, Centennial, Colorado
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado
Saint Francis Cancer Center, Colorado Springs, Colorado
Cancer Center of Colorado at Sloan's Lake, Denver, Colorado
Kaiser Permanente-Franklin, Denver, Colorado
National Jewish Health-Main Campus, Denver, Colorado
The Women's Imaging Center, Denver, Colorado
AdventHealth Porter, Denver, Colorado
Colorado Blood Cancer Institute, Denver, Colorado
Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado
Rocky Mountain Cancer Centers-Midtown, Denver, Colorado
Saint Joseph Hospital - Cancer Centers of Colorado, Denver, Colorado
Rocky Mountain Cancer Centers-Rose, Denver, Colorado
Rose Medical Center, Denver, Colorado
Western Surgical Care, Denver, Colorado
Mercy Medical Center, Durango, Colorado
Southwest Oncology PC, Durango, Colorado
Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado
Rocky Mountain Cancer Centers - Swedish, Englewood, Colorado
Swedish Medical Center, Englewood, Colorado
The Melanoma and Skin Cancer Institute, Englewood, Colorado
Poudre Valley Hospital, Fort Collins, Colorado
Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado
Mountain Blue Cancer Care Center, Golden, Colorado
National Jewish Health-Western Hematology Oncology, Golden, Colorado
Saint Mary's Hospital and Regional Medical Center, Grand Junction, Colorado
Grand Valley Oncology, Grand Junction, Colorado
Banner North Colorado Medical Center, Greeley, Colorado
UCHealth Greeley Hospital, Greeley, Colorado
UCHealth Highlands Ranch Hospital, Highlands Ranch, Colorado
Good Samaritan Hospital - Cancer Centers of Colorado, Lafayette, Colorado
Kaiser Permanente-Rock Creek, Lafayette, Colorado
Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado
Saint Anthony Hospital, Lakewood, Colorado
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado
AdventHealth Littleton, Littleton, Colorado
Kaiser Permanente-Lone Tree, Lone Tree, Colorado
Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado
Sky Ridge Medical Center, Lone Tree, Colorado
Longmont United Hospital, Longmont, Colorado
Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado
Medical Center of the Rockies, Loveland, Colorado
Banner McKee Medical Center, Loveland, Colorado
AdventHealth Parker, Parker, Colorado
Rocky Mountain Cancer Centers-Parker, Parker, Colorado
Saint Mary Corwin Medical Center, Pueblo, Colorado
Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado
National Jewish Health-Northern Hematology Oncology, Thornton, Colorado
Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado
Intermountain Health Lutheran Hospital, Wheat Ridge, Colorado
Smilow Cancer Hospital-Derby Care Center, Derby, Connecticut
Smilow Cancer Hospital Care Center-Fairfield, Fairfield, Connecticut
Smilow Cancer Hospital Care Center - Guilford, Guilford, Connecticut
Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut
Smilow Cancer Center/Yale-New Haven Hospital, New Haven, Connecticut
Yale University, New Haven, Connecticut
Yale-New Haven Hospital North Haven Medical Center, North Haven, Connecticut
Smilow Cancer Hospital-Orange Care Center, Orange, Connecticut
Smilow Cancer Hospital Care Center at Long Ridge, Stamford, Connecticut
Stamford Hospital/Bennett Cancer Center, Stamford, Connecticut
Smilow Cancer Hospital-Torrington Care Center, Torrington, Connecticut
Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut
Smilow Cancer Hospital-Waterbury Care Center, Waterbury, Connecticut
Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut
Veterans Affairs Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut
Beebe Medical Center, Lewes, Delaware
Beebe South Coastal Health Campus, Millville, Delaware
Delaware Clinical and Laboratory Physicians PA, Newark, Delaware
Helen F Graham Cancer Center, Newark, Delaware
Medical Oncology Hematology Consultants PA, Newark, Delaware
Christiana Care Health System-Christiana Hospital, Newark, Delaware
Beebe Health Campus, Rehoboth Beach, Delaware
TidalHealth Nanticoke / Allen Cancer Center, Seaford, Delaware
Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware
MedStar Georgetown University Hospital, Washington, District of Columbia
MedStar Washington Hospital Center, Washington, District of Columbia
Sibley Memorial Hospital, Washington, District of Columbia
George Washington University Medical Center, Washington, District of Columbia
GenesisCare USA - Aventura FP, Aventura, Florida
GenesisCare USA - Aventura, Aventura, Florida
Mount Sinai Comprehensive Cancer Center at Aventura, Aventura, Florida
GenesisCare USA - Boca Raton FP02, Boca Raton, Florida
GenesisCare USA - Boca Ration FP06, Boca Raton, Florida
Holy Cross Hospital, Fort Lauderdale, Florida
GenesisCare USA - Gladiolus, Fort Myers, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Mayo Clinic in Florida, Jacksonville, Florida
GenesisCare USA - Key West, Key West, Florida
GenesisCare USA - Lakewood Ranch, Lakewood Ranch, Florida
Mount Sinai Medical Center, Miami Beach, Florida
GenesisCare USA - Palm Beach Gardens, Palm Beach Gardens, Florida
Sacred Heart Hospital, Pensacola, Florida
GenesisCare USA - Plantation, Plantation, Florida
Moffitt Cancer Center-International Plaza, Tampa, Florida
Moffitt Cancer Center - McKinley Campus, Tampa, Florida
Moffitt Cancer Center, Tampa, Florida
Good Samaritan Medical Center, West Palm Beach, Florida
Cleveland Clinic-Weston, Weston, Florida
University Cancer and Blood Center LLC, Athens, Georgia
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Emory Saint Joseph's Hospital, Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Augusta Oncology Associates PC-D'Antignac, Augusta, Georgia
Augusta Oncology Associates PC-Wheeler, Augusta, Georgia
Augusta University Medical Center, Augusta, Georgia
Northeast Georgia Medical Center Braselton, Braselton, Georgia
Atlanta VA Medical Center, Decatur, Georgia
Northside Hospital - Duluth, Duluth, Georgia
Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia
The Longstreet Clinic - Gainesville, Gainesville, Georgia
Northside Hospital - Gwinnett, Lawrenceville, Georgia
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia
Summit Cancer Care-Candler, Savannah, Georgia
Suburban Hematology Oncology Associates - Snellville, Snellville, Georgia
Lewis Hall Singletary Oncology Center, Thomasville, Georgia
South Georgia Medical Center/Pearlman Cancer Center, Valdosta, Georgia
Hawaii Cancer Care - Westridge, 'Aiea, Hawaii
Pali Momi Medical Center, 'Aiea, Hawaii
Queen's Cancer Center - Pearlridge, 'Aiea, Hawaii
Straub Pearlridge Clinic, 'Aiea, Hawaii
The Cancer Center of Hawaii-Pali Momi, 'Aiea, Hawaii
The Queen's Medical Center - West Oahu, 'Ewa Beach, Hawaii
Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii
Island Urology, Honolulu, Hawaii
Queen's Cancer Cenrer - POB I, Honolulu, Hawaii
Queen's Medical Center, Honolulu, Hawaii
Straub Clinic and Hospital, Honolulu, Hawaii
University of Hawaii Cancer Center, Honolulu, Hawaii
Hawaii Cancer Care Inc-Liliha, Honolulu, Hawaii
Hawaii Diagnostic Radiology Services LLC, Honolulu, Hawaii
Kuakini Medical Center, Honolulu, Hawaii
Queen's Cancer Center - Kuakini, Honolulu, Hawaii
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Straub Medical Center - Kahului Clinic, Kahului, Hawaii
Castle Medical Center, Kailua, Hawaii
Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Walter Knox Memorial Hospital, Emmett, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Idaho Urologic Institute-Meridian, Meridian, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho
Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho
OSF Saint Anthony's Health Center, Alton, Illinois
Rush-Copley Medical Center, Aurora, Illinois
Advocate Good Shepherd Hospital, Barrington, Illinois
Illinois CancerCare-Bloomington, Bloomington, Illinois
Loyola Center for Health at Burr Ridge, Burr Ridge, Illinois
Illinois CancerCare-Canton, Canton, Illinois
Memorial Hospital of Carbondale, Carbondale, Illinois
SIH Cancer Institute, Carterville, Illinois
Illinois CancerCare-Carthage, Carthage, Illinois
Centralia Oncology Clinic, Centralia, Illinois
Saint Mary's Hospital, Centralia, Illinois
Northwestern University, Chicago, Illinois
Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois
John H Stroger Jr Hospital of Cook County, Chicago, Illinois
Rush University Medical Center, Chicago, Illinois
Swedish Covenant Hospital, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Advocate Illinois Masonic Medical Center, Chicago, Illinois
AMG Crystal Lake - Oncology, Crystal Lake, Illinois
Carle at The Riverfront, Danville, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Illinois CancerCare-Dixon, Dixon, Illinois
Advocate Good Samaritan Hospital, Downers Grove, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
Crossroads Cancer Center, Effingham, Illinois
Advocate Sherman Hospital, Elgin, Illinois
Elmhurst Memorial Hospital, Elmhurst, Illinois
Illinois CancerCare-Eureka, Eureka, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
Freeport Memorial Hospital/Leonard C Ferguson Cancer Center, Freeport, Illinois
Illinois CancerCare-Galesburg, Galesburg, Illinois
Western Illinois Cancer Treatment Center, Galesburg, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
Advocate South Suburban Hospital, Hazel Crest, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
Edward Hines Jr VA Hospital, Hines, Illinois
UChicago Medicine AdventHealth Cancer Institute Hinsdale, Hinsdale, Illinois
Loyola Medicine Homer Glen, Homer Glen, Illinois
Duly Health and Care Joliet, Joliet, Illinois
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois
Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois
AMG Libertyville - Oncology, Libertyville, Illinois
Condell Memorial Hospital, Libertyville, Illinois
Illinois CancerCare-Macomb, Macomb, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
Loyola University Medical Center, Maywood, Illinois
Marjorie Weinberg Cancer Center at Loyola-Gottlieb, Melrose Park, Illinois
SSM Health Good Samaritan, Mount Vernon, Illinois
Edward Hospital/Cancer Center, Naperville, Illinois
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois
Advocate Christ Medical Center, Oak Lawn, Illinois
Northwestern Medicine Orland Park, Orland Park, Illinois
University of Chicago Medicine-Orland Park, Orland Park, Illinois
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois
Advocate Lutheran General Hospital, Park Ridge, Illinois
Illinois CancerCare-Pekin, Pekin, Illinois
Illinois CancerCare-Peoria, Peoria, Illinois
Methodist Medical Center of Illinois, Peoria, Illinois
Illinois CancerCare-Peru, Peru, Illinois
Valley Radiation Oncology, Peru, Illinois
Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois
Illinois CancerCare-Princeton, Princeton, Illinois
UW Health Carbone Cancer Center Rockford, Rockford, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Springfield Memorial Hospital, Springfield, Illinois
Southwest Illinois Health Services LLP, Swansea, Illinois
Carle Cancer Center, Urbana, Illinois
The Carle Foundation Hospital, Urbana, Illinois
Illinois CancerCare - Washington, Washington, Illinois
Rush-Copley Healthcare Center, Yorkville, Illinois
Reid Health, Richmond, Indiana
Mary Greeley Medical Center, Ames, Iowa
McFarland Clinic - Ames, Ames, Iowa
UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa
University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf, Iowa
McFarland Clinic - Boone, Boone, Iowa
Saint Anthony Regional Hospital, Carroll, Iowa
Mercy Hospital, Cedar Rapids, Iowa
Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa
Mercy Cancer Center-West Lakes, Clive, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa
Alegent Health Mercy Hospital, Council Bluffs, Iowa
Heartland Oncology and Hematology LLP, Council Bluffs, Iowa
Methodist Jennie Edmundson Hospital, Council Bluffs, Iowa
Greater Regional Medical Center, Creston, Iowa
Iowa Methodist Medical Center, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa
Broadlawns Medical Center, Des Moines, Iowa
Mercy Medical Center - Des Moines, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa
Iowa Lutheran Hospital, Des Moines, Iowa
McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa
Trinity Regional Medical Center, Fort Dodge, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
McFarland Clinic - Jefferson, Jefferson, Iowa
McFarland Clinic - Marshalltown, Marshalltown, Iowa
Siouxland Regional Cancer Center, Sioux City, Iowa
MercyOne Waterloo Cancer Center, Waterloo, Iowa
Methodist West Hospital, West Des Moines, Iowa
Mercy Medical Center-West Lakes, West Des Moines, Iowa
Cancer Center of Kansas - Chanute, Chanute, Kansas
Coffeyville Regional Medical Center, Coffeyville, Kansas
Cancer Center of Kansas - Dodge City, Dodge City, Kansas
Cancer Center of Kansas - El Dorado, El Dorado, Kansas
University of Kansas Clinical Research Center, Fairway, Kansas
Central Care Cancer Center - Garden City, Garden City, Kansas
Central Care Cancer Center - Great Bend, Great Bend, Kansas
HaysMed, Hays, Kansas
Cancer Center of Kansas-Independence, Independence, Kansas
University of Kansas Cancer Center-West, Kansas City, Kansas
Cancer Center of Kansas-Kingman, Kingman, Kansas
Lawrence Memorial Hospital, Lawrence, Kansas
Cancer Center of Kansas-Liberal, Liberal, Kansas
Cancer Center of Kansas-Manhattan, Manhattan, Kansas
Cancer Center of Kansas - McPherson, McPherson, Kansas
Cancer Center of Kansas - Newton, Newton, Kansas
The University of Kansas Cancer Center - Olathe, Olathe, Kansas
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas
Saint Luke's South Hospital, Overland Park, Kansas
Cancer Center of Kansas - Parsons, Parsons, Kansas
Freeman Physician Group of Pittsburg, Pittsburg, Kansas
Mercy Hospital Pittsburg, Pittsburg, Kansas
Cancer Center of Kansas - Pratt, Pratt, Kansas
Cancer Center of Kansas - Salina, Salina, Kansas
Salina Regional Health Center, Salina, Kansas
University of Kansas Health System Saint Francis Campus, Topeka, Kansas
Cancer Center of Kansas - Wellington, Wellington, Kansas
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas
Ascension Via Christi Hospitals Wichita, Wichita, Kansas
Cancer Center of Kansas - Wichita, Wichita, Kansas
Cancer Center of Kansas - Winfield, Winfield, Kansas
Flaget Memorial Hospital, Bardstown, Kentucky
Commonwealth Cancer Center-Corbin, Corbin, Kentucky
Saint Joseph Hospital, Lexington, Kentucky
Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky
Saint Joseph Hospital East, Lexington, Kentucky
Saint Joseph London, London, Kentucky
Jewish Hospital, Louisville, Kentucky
Saints Mary and Elizabeth Hospital, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
Saint Joseph Mount Sterling, Mount Sterling, Kentucky
Mercy Health - Paducah Cancer Center, Paducah, Kentucky
Jewish Hospital Medical Center South, Shepherdsville, Kentucky
West Jefferson Medical Center, Marrero, Louisiana
Ochsner LSU Health Monroe Medical Center, Monroe, Louisiana
Louisiana State University Health Science Center, New Orleans, Louisiana
University Medical Center New Orleans, New Orleans, Louisiana
Veteran's Administration Medical Center - New Orleans, New Orleans, Louisiana
LSU Health Sciences Center at Shreveport, Shreveport, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Lafayette Family Cancer Center-EMMC, Brewer, Maine
Greater Baltimore Medical Center, Baltimore, Maryland
MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore, Maryland
MedStar Good Samaritan Hospital, Baltimore, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
University of Maryland Shore Medical Center at Easton, Easton, Maryland
Christiana Care - Union Hospital, Elkton, Maryland
Beverly Hospital, Beverly, Massachusetts
Lahey Hospital and Medical Center, Burlington, Massachusetts
Addison Gilbert Hospital, Gloucester, Massachusetts
Lowell General Hospital, Lowell, Massachusetts
Lahey Medical Center-Peabody, Peabody, Massachusetts
Mercy Medical Center, Springfield, Massachusetts
Baystate Medical Center, Springfield, Massachusetts
Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care, Winchester, Massachusetts
UMass Memorial Medical Center - University Campus, Worcester, Massachusetts
Hickman Cancer Center, Adrian, Michigan
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
Bronson Battle Creek, Battle Creek, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health Medical Center - Canton, Canton, Michigan
Caro Cancer Center, Caro, Michigan
Chelsea Hospital, Chelsea, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Hematology Oncology Consultants-Clarkston, Clarkston, Michigan
Michigan Healthcare Professionals Clarkston, Clarkston, Michigan
Newland Medical Associates-Clarkston, Clarkston, Michigan
Henry Ford Health Saint John Hospital, Detroit, Michigan
Henry Ford River District Hospital, East China Township, Michigan
OSF Saint Francis Hospital and Medical Group, Escanaba, Michigan
Michigan Healthcare Professionals Farmington, Farmington Hills, Michigan
Cancer Hematology Centers - Flint, Flint, Michigan
Genesee Hematology Oncology PC, Flint, Michigan
Genesys Hurley Cancer Institute, Flint, Michigan
Hurley Medical Center, Flint, Michigan
Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan
Henry Ford Saint John Hospital - Academic, Grosse Pointe Woods, Michigan
Henry Ford Saint John Hospital - Breast, Grosse Pointe Woods, Michigan
Henry Ford Saint John Hospital - Van Elslander, Grosse Pointe Woods, Michigan
Bronson Methodist Hospital, Kalamazoo, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
Beacon Kalamazoo Cancer Center, Kalamazoo, Michigan
Ascension Borgess Hospital, Kalamazoo, Michigan
University of Michigan Health - Sparrow Lansing, Lansing, Michigan
Hope Cancer Clinic, Livonia, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Saint John Hospital - Macomb Medical, Macomb, Michigan
Henry Ford Warren Hospital - Breast Macomb, Macomb, Michigan
Michigan Healthcare Professionals Macomb, Macomb, Michigan
Michigan Healthcare Professionals Madison Heights, Madison Heights, Michigan
Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan
Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan
Trinity Health Muskegon Hospital, Muskegon, Michigan
Corewell Health Lakeland Hospitals - Niles Hospital, Niles, Michigan
Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan
Henry Ford Health Providence Novi Hospital, Novi, Michigan
Hope Cancer Center, Pontiac, Michigan
Michigan Healthcare Professionals Pontiac, Pontiac, Michigan
Newland Medical Associates-Pontiac, Pontiac, Michigan
Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan
Huron Medical Center PC, Port Huron, Michigan
Lake Huron Medical Center, Port Huron, Michigan
Corewell Health Reed City Hospital, Reed City, Michigan
Henry Ford Rochester Hospital, Rochester Hills, Michigan
MyMichigan Medical Center Saginaw, Saginaw, Michigan
Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan
Corewell Health Lakeland Hospitals - Saint Joseph Hospital, Saint Joseph, Michigan
Henry Ford Health Providence Southfield Hospital, Southfield, Michigan
Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan
MyMichigan Medical Center Tawas, Tawas City, Michigan
Munson Medical Center, Traverse City, Michigan
Michigan Healthcare Professionals Troy, Troy, Michigan
Advanced Breast Care Center PLLC, Warren, Michigan
Henry Ford Health Warren Hospital, Warren, Michigan
Henry Ford Madison Heights Hospital - Breast, Warren, Michigan
Henry Ford Warren Hospital - GLCMS, Warren, Michigan
Macomb Hematology Oncology PC, Warren, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan
University of Michigan Health - West, Wyoming, Michigan
Huron Gastroenterology PC, Ypsilanti, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Riverwood Healthcare Center, Aitkin, Minnesota
Mayo Clinic Health System in Albert Lea, Albert Lea, Minnesota
Essentia Health - Baxter Clinic, Baxter, Minnesota
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota
Fairview Ridges Hospital, Burnsville, Minnesota
Minnesota Oncology - Burnsville, Burnsville, Minnesota
Cambridge Medical Center, Cambridge, Minnesota
Mercy Hospital, Coon Rapids, Minnesota
Essentia Health - Deer River Clinic, Deer River, Minnesota
Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota
Essentia Health Cancer Center, Duluth, Minnesota
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota
Miller-Dwan Hospital, Duluth, Minnesota
Fairview Southdale Hospital, Edina, Minnesota
Essentia Health - Ely Clinic, Ely, Minnesota
Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota
Essentia Health - Fosston, Fosston, Minnesota
Unity Hospital, Fridley, Minnesota
Essentia Health Hibbing Clinic, Hibbing, Minnesota
Essentia Health - International Falls Clinic, International Falls, Minnesota
Mayo Clinic Health Systems-Mankato, Mankato, Minnesota
Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota
Saint John's Hospital - Healtheast, Maplewood, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
Hennepin County Medical Center, Minneapolis, Minnesota
Minneapolis VA Medical Center, Minneapolis, Minnesota
Health Partners Inc, Minneapolis, Minnesota
Monticello Cancer Center, Monticello, Minnesota
Essentia Health - Moose Lake Clinic, Moose Lake, Minnesota
New Ulm Medical Center, New Ulm, Minnesota
Essentia Health - Park Rapids, Park Rapids, Minnesota
Fairview Northland Medical Center, Princeton, Minnesota
North Memorial Medical Health Center, Robbinsdale, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota
Regions Hospital, Saint Paul, Minnesota
United Hospital, Saint Paul, Minnesota
Essentia Health Sandstone, Sandstone, Minnesota
Saint Francis Regional Medical Center, Shakopee, Minnesota
Lakeview Hospital, Stillwater, Minnesota
Sanford Thief River Falls Medical Center, Thief River Falls, Minnesota
Essentia Health Virginia Clinic, Virginia, Minnesota
Ridgeview Medical Center, Waconia, Minnesota
Rice Memorial Hospital, Willmar, Minnesota
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota
Sanford Cancer Center Worthington, Worthington, Minnesota
Fairview Lakes Medical Center, Wyoming, Minnesota
Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus, Mississippi
Baptist Cancer Center-Grenada, Grenada, Mississippi
Baptist Memorial Hospital and Cancer Center-Union County, New Albany, Mississippi
Baptist Memorial Hospital and Cancer Center-Oxford, Oxford, Mississippi
Singing River Hospital, Pascagoula, Mississippi
Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi
Mercy Oncology and Hematology - Clayton-Clarkson, Ballwin, Missouri
Central Care Cancer Center - Bolivar, Bolivar, Missouri
Parkland Health Center-Bonne Terre, Bonne Terre, Missouri
Cox Cancer Center Branson, Branson, Missouri
Mercy Cancer Center - Cape Girardeau, Cape Girardeau, Missouri
Saint Francis Medical Center, Cape Girardeau, Missouri
Saint Luke's Hospital, Chesterfield, Missouri
Parkland Health Center - Farmington, Farmington, Missouri
MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri
Freeman Health System, Joplin, Missouri
Mercy Hospital Joplin, Joplin, Missouri
University Health Truman Medical Center, Kansas City, Missouri
Saint Luke's Hospital of Kansas City, Kansas City, Missouri
The University of Kansas Cancer Center-South, Kansas City, Missouri
University of Kansas Cancer Center - North, Kansas City, Missouri
University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri
Saint Luke's East - Lee's Summit, Lee's Summit, Missouri
University of Kansas Cancer Center at North Kansas City Hospital, North Kansas City, Missouri
Lake Regional Hospital, Osage Beach, Missouri
Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri
Phelps Health Delbert Day Cancer Institute, Rolla, Missouri
Heartland Regional Medical Center, Saint Joseph, Missouri
Mercy Infusion Center - Chippewa, Saint Louis, Missouri
Mercy Hospital South, Saint Louis, Missouri
Missouri Baptist Medical Center, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri
Mercy Hospital Springfield, Springfield, Missouri
CoxHealth South Hospital, Springfield, Missouri
Missouri Baptist Sullivan Hospital, Sullivan, Missouri
BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri
Mercy Hospital Washington, Washington, Missouri
Community Hospital of Anaconda, Anaconda, Montana
Billings Clinic Cancer Center, Billings, Montana
Saint Vincent Healthcare, Billings, Montana
Saint Vincent Frontier Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Great Falls Clinic, Great Falls, Montana
Saint Peter's Community Hospital, Helena, Montana
Logan Health Medical Center, Kalispell, Montana
Saint Patrick Hospital - Community Hospital, Missoula, Montana
Community Medical Center, Missoula, Montana
Nebraska Medicine-Bellevue, Bellevue, Nebraska
Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska
Fred and Pamela Buffett Cancer Center - Kearney, Kearney, Nebraska
CHI Health Good Samaritan, Kearney, Nebraska
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska
Nebraska Methodist Hospital, Omaha, Nebraska
Oncology Associates PC, Omaha, Nebraska
Nebraska Medicine-Village Pointe, Omaha, Nebraska
Alegent Health Immanuel Medical Center, Omaha, Nebraska
Hematology and Oncology Consultants PC, Omaha, Nebraska
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska
Alegent Health Lakeside Hospital, Omaha, Nebraska
Creighton University Medical Center, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Midlands Community Hospital, Papillion, Nebraska
Carson Tahoe Regional Medical Center, Carson City, Nevada
Cancer and Blood Specialists-Henderson, Henderson, Nevada
Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada
Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada
Las Vegas Cancer Center-Henderson, Henderson, Nevada
OptumCare Cancer Care at Seven Hills, Henderson, Nevada
Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada
GenesisCare USA - Henderson, Henderson, Nevada
Las Vegas Urology - Green Valley, Henderson, Nevada
Las Vegas Urology - Pebble, Henderson, Nevada
Urology Specialists of Nevada - Green Valley, Henderson, Nevada
Las Vegas Urology - Pecos, Las Vegas, Nevada
Desert West Surgery, Las Vegas, Nevada
OptumCare Cancer Care at Charleston, Las Vegas, Nevada
University Medical Center of Southern Nevada, Las Vegas, Nevada
Hope Cancer Care of Nevada, Las Vegas, Nevada
Cancer and Blood Specialists-Shadow, Las Vegas, Nevada
Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada
Urology Specialists of Nevada - Central, Las Vegas, Nevada
GenesisCare USA - Las Vegas, Las Vegas, Nevada
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada
Sunrise Hospital and Medical Center, Las Vegas, Nevada
HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada
Las Vegas Prostate Cancer Center, Las Vegas, Nevada
Las Vegas Urology - Sunset, Las Vegas, Nevada
Urology Specialists of Nevada - Southwest, Las Vegas, Nevada
Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada
Ann M Wierman MD LTD, Las Vegas, Nevada
Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada
GenesisCare USA - Vegas Tenaya, Las Vegas, Nevada
HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada
Las Vegas Urology - Cathedral Rock, Las Vegas, Nevada
Las Vegas Urology - Smoke Ranch, Las Vegas, Nevada
OptumCare Cancer Care at MountainView, Las Vegas, Nevada
Urology Specialists of Nevada - Northwest, Las Vegas, Nevada
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada - Town Center, Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada
Summerlin Hospital Medical Center, Las Vegas, Nevada
Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
GenesisCare USA - Fort Apache, Las Vegas, Nevada
OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada
University Cancer Center, Las Vegas, Nevada
Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada
Renown Regional Medical Center, Reno, Nevada
Saint Mary's Regional Medical Center, Reno, Nevada
Radiation Oncology Associates, Reno, Nevada
New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Elliot Hospital, Manchester, New Hampshire
Solinsky Center for Cancer Care, Manchester, New Hampshire
Virtua Samson Cancer Center, Moorestown, New Jersey
Morristown Medical Center, Morristown, New Jersey
Inspira Medical Center Mullica Hill, Mullica Hill, New Jersey
Overlook Hospital, Summit, New Jersey
Virtua Voorhees, Voorhees, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Hematology Oncology Associates of Central New York-Auburn, Auburn, New York
Lourdes Hospital, Binghamton, New York
Montefiore Medical Center-Einstein Campus, Bronx, New York
Montefiore Medical Center-Weiler Hospital, Bronx, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
James J Peters VA Medical Center, Bronx, New York
Hematology Oncology Associates of CNY at Camillus, Camillus, New York
Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York
Glens Falls Hospital, Glens Falls, New York
Mount Sinai Chelsea, New York, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Mount Sinai West, New York, New York
Mount Sinai Hospital, New York, New York
Upstate Cancer Center at Oswego, Oswego, New York
University of Rochester, Rochester, New York
Stony Brook University Medical Center, Stony Brook, New York
State University of New York Upstate Medical University, Syracuse, New York
SUNY Upstate Medical Center-Community Campus, Syracuse, New York
Upstate Cancer Center at Verona, Verona, New York
Wilmot Cancer Institute at Webster, Webster, New York
Atrium Health Stanly/LCI-Albemarle, Albemarle, North Carolina
Mission Hospital, Asheville, North Carolina
AdventHealth Infusion Center Asheville, Asheville, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Atrium Health Pineville/LCI-Pineville, Charlotte, North Carolina
Levine Cancer Institute-SouthPark, Charlotte, North Carolina
Atrium Health University City/LCI-University, Charlotte, North Carolina
Levine Cancer Institute-Ballantyne, Charlotte, North Carolina
Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina
AdventHealth Infusion Center Haywood, Clyde, North Carolina
Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina
Durham VA Medical Center, Durham, North Carolina
Levine Cancer Institute - Rutherford, Forest City, North Carolina
Levine Cancer Institute-Gaston, Gastonia, North Carolina
Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina
East Carolina University, Greenville, North Carolina
Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina
AdventHealth Hendersonville, Hendersonville, North Carolina
Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina
ECU Health Oncology Kenansville, Kenansville, North Carolina
ECU Health Oncology Kinston, Kinston, North Carolina
Atrium Health Lincoln/LCI-Lincolnton, Lincolnton, North Carolina
Levine Cancer Institute - Union West, Matthews, North Carolina
Atrium Health Union/LCI-Union, Monroe, North Carolina
ECU Health Oncology Richlands, Richlands, North Carolina
WG Hefner VA Medical Center, Salisbury, North Carolina
Atrium Health Cleveland/LCI-Cleveland, Shelby, North Carolina
AdventHealth Infusion Center Weaverville, Weaverville, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota
Sanford South University Medical Center, Fargo, North Dakota
Southpointe-Sanford Medical Center Fargo, Fargo, North Dakota
Sanford Medical Center Fargo, Fargo, North Dakota
Sanford Broadway Medical Center, Fargo, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Essentia Health - Jamestown Clinic, Jamestown, North Dakota
UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio
Indu and Raj Soin Medical Center, Beavercreek, Ohio
Strecker Cancer Center-Belpre, Belpre, Ohio
Saint Elizabeth Boardman Hospital, Boardman, Ohio
Cleveland Clinic Mercy Hospital, Canton, Ohio
Dayton Physicians LLC-Miami Valley South, Centerville, Ohio
Miami Valley Hospital South, Centerville, Ohio
Geauga Hospital, Chardon, Ohio
Adena Regional Medical Center, Chillicothe, Ohio
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio
Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio
Bethesda North Hospital, Cincinnati, Ohio
TriHealth Cancer Institute-Westside, Cincinnati, Ohio
TriHealth Cancer Institute-Anderson, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Mount Carmel East Hospital, Columbus, Ohio
Columbus Oncology and Hematology Associates Inc, Columbus, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Grant Medical Center, Columbus, Ohio
The Mark H Zangmeister Center, Columbus, Ohio
Mount Carmel Health Center West, Columbus, Ohio
Doctors Hospital, Columbus, Ohio
Good Samaritan Hospital - Dayton, Dayton, Ohio
Miami Valley Hospital, Dayton, Ohio
Premier Blood and Cancer Center, Dayton, Ohio
Dayton Physician LLC - Englewood, Dayton, Ohio
Miami Valley Hospital North, Dayton, Ohio
Delaware Health Center-Grady Cancer Center, Delaware, Ohio
Grady Memorial Hospital, Delaware, Ohio
Columbus Oncology and Hematology Associates, Dublin, Ohio
Dublin Methodist Hospital, Dublin, Ohio
Mercy Cancer Center-Elyria, Elyria, Ohio
Armes Family Cancer Center, Findlay, Ohio
Blanchard Valley Hospital, Findlay, Ohio
Orion Cancer Care, Findlay, Ohio
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio
Dayton Physicians LLC-Atrium, Franklin, Ohio
Central Ohio Breast and Endocrine Surgery, Gahanna, Ohio
Dayton Physicians LLC-Wayne, Greenville, Ohio
Miami Valley Cancer Care and Infusion, Greenville, Ohio
Wayne Hospital, Greenville, Ohio
Mount Carmel Grove City Hospital, Grove City, Ohio
Zangmeister Center Grove City, Grove City, Ohio
Cleveland Clinic Cancer Center Independence, Independence, Ohio
Greater Dayton Cancer Center, Kettering, Ohio
First Dayton Cancer Care, Kettering, Ohio
Kettering Medical Center, Kettering, Ohio
Fairfield Medical Center, Lancaster, Ohio
Saint Rita's Medical Center, Lima, Ohio
OhioHealth Mansfield Hospital, Mansfield, Ohio
Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio
Marietta Memorial Hospital, Marietta, Ohio
OhioHealth Marion General Hospital, Marion, Ohio
Memorial Hospital, Marysville, Ohio
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio
UH Seidman Cancer Center at Landerbrook Health Center, Mayfield Heights, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights, Ohio
Knox Community Hospital, Mount Vernon, Ohio
Mount Carmel New Albany Surgical Hospital, New Albany, Ohio
Licking Memorial Hospital, Newark, Ohio
Newark Radiation Oncology, Newark, Ohio
University Hospitals Parma Medical Center, Parma, Ohio
Mercy Health - Perrysburg Hospital, Perrysburg, Ohio
Southern Ohio Medical Center, Portsmouth, Ohio
University Hospitals Portage Medical Center, Ravenna, Ohio
North Coast Cancer Care, Sandusky, Ohio
UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio
Springfield Regional Cancer Center, Springfield, Ohio
Springfield Regional Medical Center, Springfield, Ohio
Trinity's Tony Teramana Cancer Center, Steubenville, Ohio
Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio
Mercy Health - Saint Vincent Hospital, Toledo, Ohio
Mercy Health - Saint Anne Hospital, Toledo, Ohio
Mercy Health Sylvania Radiation Oncology Center, Toledo, Ohio
Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio
Dayton Physicians LLC - Troy, Troy, Ohio
Upper Valley Medical Center, Troy, Ohio
University Hospitals Sharon Health Center, Wadsworth, Ohio
South Pointe Hospital, Warrensville Heights, Ohio
Saint Joseph Warren Hospital, Warren, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
Saint Ann's Hospital, Westerville, Ohio
UH Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio
UHHS-Westlake Medical Center, Westlake, Ohio
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center, Wilmington, Ohio
Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio
Saint Elizabeth Youngstown Hospital, Youngstown, Ohio
Genesis Healthcare System Cancer Care Center, Zanesville, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma
Saint Alphonsus Cancer Care Center-Baker City, Baker City, Oregon
Saint Charles Health System, Bend, Oregon
Clackamas Radiation Oncology Center, Clackamas, Oregon
Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon
Bay Area Hospital, Coos Bay, Oregon
Providence Newberg Medical Center, Newberg, Oregon
Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon
Providence Willamette Falls Medical Center, Oregon City, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
Saint Charles Health System-Redmond, Redmond, Oregon
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania
UPMC Altoona, Altoona, Pennsylvania
UPMC Cancer Center-Bethel Park, Bethel Park, Pennsylvania
Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania
Bryn Mawr Hospital, Bryn Mawr, Pennsylvania
UPMC Camp Hill, Camp Hill, Pennsylvania
Carlisle Regional Cancer Center, Carlisle, Pennsylvania
Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania
Chambersburg Hospital, Chambersburg, Pennsylvania
WellSpan Medical Oncology and Hematology, Chambersburg, Pennsylvania
Pocono Medical Center, East Stroudsburg, Pennsylvania
Ephrata Cancer Center, Ephrata, Pennsylvania
Ephrata Community Hospital, Ephrata, Pennsylvania
UPMC Hillman Cancer Center Erie, Erie, Pennsylvania
Adams Cancer Center, Gettysburg, Pennsylvania
UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania
WellSpan Medical Oncology and Hematology, Hanover, Pennsylvania
UPMC Pinnacle Harrisburg, Harrisburg, Pennsylvania
UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania
Lehigh Valley Hospital-Hazleton, Hazleton, Pennsylvania
Sechler Family Cancer Center, Lebanon, Pennsylvania
UPMC Cancer Center at UPMC McKeesport, McKeesport, Pennsylvania
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania
Riddle Memorial Hospital, Media, Pennsylvania
Arnold Palmer Cancer Center Medical Oncology Norwin, N. Huntingdon, Pennsylvania
Paoli Memorial Hospital, Paoli, Pennsylvania
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Temple University Hospital, Philadelphia, Pennsylvania
Oncology Hematology Association, Pittsburgh, Pennsylvania
UPMC-Saint Margaret, Pittsburgh, Pennsylvania
UPMC-Mercy Hospital, Pittsburgh, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
UPMC-Passavant Hospital, Pittsburgh, Pennsylvania
UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania
Pottstown Hospital, Pottstown, Pennsylvania
UPMC Cancer Center at UPMC Northwest, Seneca, Pennsylvania
UPMC Cancer Center-Washington, Washington, Pennsylvania
Lankenau Medical Center, Wynnewood, Pennsylvania
Cancer Care Associates of York, York, Pennsylvania
WellSpan Health-York Cancer Center, York, Pennsylvania
WellSpan Health-York Hospital, York, Pennsylvania
UPMC Memorial, York, Pennsylvania
Kent Hospital, Warwick, Rhode Island
Smilow Cancer Hospital Care Center - Westerly, Westerly, Rhode Island
Saint Joseph's/Candler - Bluffton Campus, Bluffton, South Carolina
Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina
Ralph H Johnson VA Medical Center, Charleston, South Carolina
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Richland Hospital, Columbia, South Carolina
Gibbs Cancer Center-Gaffney, Gaffney, South Carolina
Tidelands Georgetown Memorial Hospital, Georgetown, South Carolina
Prisma Health Cancer Institute - Butternut, Greenville, South Carolina
Prisma Health Cancer Institute - Faris, Greenville, South Carolina
Prisma Health Greenville Memorial Hospital, Greenville, South Carolina
Prisma Health Cancer Institute - Eastside, Greenville, South Carolina
Self Regional Healthcare, Greenwood, South Carolina
Prisma Health Cancer Institute - Greer, Greer, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
South Carolina Cancer Specialists PC, Hilton Head Island, South Carolina
Carolina Regional Cancer Center, Myrtle Beach, South Carolina
Levine Cancer Institute-Rock Hill, Rock Hill, South Carolina
Prisma Health Cancer Institute - Seneca, Seneca, South Carolina
North Grove Medical Park, Spartanburg, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
Spartanburg Medical Center - Mary Black Campus, Spartanburg, South Carolina
SMC Center for Hematology Oncology Union, Union, South Carolina
Rapid City Regional Hospital, Rapid City, South Dakota
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
University Cancer Specialists - Alcoa, Alcoa, Tennessee
Bristol Regional Medical Center, Bristol, Tennessee
Memorial Hospital, Chattanooga, Tennessee
Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee
Vanderbilt-Ingram Cancer Center at Franklin, Franklin, Tennessee
Vanderbilt-Ingram Cancer Center Cool Springs, Franklin, Tennessee
Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee
Ballad Health Cancer Care - Kingsport, Kingsport, Tennessee
Wellmont Holston Valley Hospital and Medical Center, Kingsport, Tennessee
University of Tennessee - Knoxville, Knoxville, Tennessee
Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee
Vanderbilt Breast Center at One Hundred Oaks, Nashville, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Memorial GYN Plus, Ooltewah, Tennessee
Houston Methodist San Jacinto Hospital, Baytown, Texas
Saint Joseph Regional Cancer Center, Bryan, Texas
Dallas VA Medical Center, Dallas, Texas
Parkland Memorial Hospital, Dallas, Texas
UT Southwestern Simmons Cancer Center - RedBird, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Tarrant County Hospital District/JPS Health Network, Fort Worth, Texas
UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas
Houston Methodist Hospital, Houston, Texas
Methodist Willowbrook Hospital, Houston, Texas
Houston Methodist West Hospital, Houston, Texas
Houston Methodist Saint John Hospital, Nassau Bay, Texas
UT Southwestern Clinical Center at Richardson/Plano, Richardson, Texas
Houston Methodist Sugar Land Hospital, Sugar Land, Texas
Houston Methodist The Woodlands Hospital, The Woodlands, Texas
American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah
Sandra L Maxwell Cancer Center, Cedar City, Utah
Logan Regional Hospital, Logan, Utah
Intermountain Medical Center, Murray, Utah
McKay-Dee Hospital Center, Ogden, Utah
Utah Valley Regional Medical Center, Provo, Utah
Riverton Hospital, Riverton, Utah
Saint George Regional Medical Center, Saint George, Utah
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah
LDS Hospital, Salt Lake City, Utah
Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont
University of Vermont Medical Center, Burlington, Vermont
University of Vermont and State Agricultural College, Burlington, Vermont
Dartmouth Cancer Center - North, Saint Johnsbury, Vermont
Ballad Health Cancer Care - Bristol, Bristol, Virginia
University of Virginia Cancer Center, Charlottesville, Virginia
Augusta Health Center for Cancer and Blood Disorders, Fishersville, Virginia
Ballad Health Cancer Care - Norton, Norton, Virginia
Virginia Cancer Institute, Richmond, Virginia
VCU Massey Cancer Center at Stony Point, Richmond, Virginia
VCU Massey Comprehensive Cancer Center, Richmond, Virginia
VCU Community Memorial Health Center, South Hill, Virginia
Providence Regional Cancer System-Aberdeen, Aberdeen, Washington
MultiCare Auburn Medical Center, Auburn, Washington
Overlake Medical Center, Bellevue, Washington
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington
Highline Medical Center-Main Campus, Burien, Washington
Providence Regional Cancer System-Centralia, Centralia, Washington
Swedish Cancer Institute-Edmonds, Edmonds, Washington
Saint Elizabeth Hospital, Enumclaw, Washington
Providence Regional Cancer Partnership, Everett, Washington
Saint Francis Hospital, Federal Way, Washington
MultiCare Gig Harbor Medical Park, Gig Harbor, Washington
Swedish Cancer Institute-Issaquah, Issaquah, Washington
Kadlec Clinic Hematology and Oncology, Kennewick, Washington
Providence Regional Cancer System-Lacey, Lacey, Washington
Saint Clare Hospital, Lakewood, Washington
PeaceHealth Saint John Medical Center, Longview, Washington
Jefferson Healthcare, Port Townsend, Washington
Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington
MultiCare Good Samaritan Hospital, Puyallup, Washington
Valley Medical Center, Renton, Washington
Pacific Gynecology Specialists, Seattle, Washington
Swedish Medical Center-Ballard Campus, Seattle, Washington
Kaiser Permanente Washington, Seattle, Washington
Swedish Medical Center-Cherry Hill, Seattle, Washington
Swedish Medical Center-First Hill, Seattle, Washington
PeaceHealth United General Medical Center, Sedro-Woolley, Washington
Providence Regional Cancer System-Shelton, Shelton, Washington
Saint Michael Cancer Center, Silverdale, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - Valley, Spokane Valley, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown, Spokane, Washington
MultiCare Deaconess Cancer and Blood Specialty Center - North, Spokane, Washington
Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
MultiCare Tacoma General Hospital, Tacoma, Washington
Northwest Medical Specialties PLLC, Tacoma, Washington
PeaceHealth Southwest Medical Center, Vancouver, Washington
Providence Saint Mary Regional Cancer Center, Walla Walla, Washington
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington
Providence Regional Cancer System-Yelm, Yelm, Washington
West Virginia University Charleston Division, Charleston, West Virginia
Edwards Comprehensive Cancer Center, Huntington, West Virginia
Langlade Hospital and Cancer Center, Antigo, Wisconsin
Ascension Saint Elizabeth Hospital, Appleton, Wisconsin
Duluth Clinic Ashland, Ashland, Wisconsin
Northwest Wisconsin Cancer Center, Ashland, Wisconsin
SSM Health Dean Medical Group - Baraboo, Baraboo, Wisconsin
Ascension Southeast Wisconsin Hospital - Elmbrook Campus, Brookfield, Wisconsin
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin
Ascension Calumet Hospital, Chilton, Wisconsin
Aurora Saint Luke's South Shore, Cudahy, Wisconsin
HSHS Sacred Heart Hospital, Eau Claire, Wisconsin
Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin
Mayo Clinic Health System-Eau Claire Clinic, Eau Claire, Wisconsin
Mayo Clinic Health System Eau Claire Hospital-Luther Campus, Eau Claire, Wisconsin
Aurora Health Center-Fond du Lac, Fond Du Lac, Wisconsin
Ascension Saint Francis - Reiman Cancer Center, Franklin, Wisconsin
Aurora Health Care Germantown Health Center, Germantown, Wisconsin
Aurora Cancer Care-Grafton, Grafton, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin
Aurora BayCare Medical Center, Green Bay, Wisconsin
Essentia Health-Hayward Clinic, Hayward, Wisconsin
SSM Health Dean Medical Group - Janesville, Janesville, Wisconsin
Mercyhealth Hospital and Cancer Center - Janesville, Janesville, Wisconsin
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
Mayo Clinic Health System-Franciscan Healthcare, La Crosse, Wisconsin
SSM Health Dean Medical Group - South Madison Campus, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Holy Family Memorial Hospital, Manitowoc, Wisconsin
Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin
Saint Vincent Hospital Cancer Center at Marinette, Marinette, Wisconsin
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
Aspirus Medford Hospital, Medford, Wisconsin
Ascension Columbia Saint Mary's Hospital Ozaukee, Mequon, Wisconsin
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin
Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee, Wisconsin
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin
Aurora Sinai Medical Center, Milwaukee, Wisconsin
Marshfield Medical Center - Minocqua, Minocqua, Wisconsin
ProHealth D N Greenwald Center, Mukwonago, Wisconsin
Cancer Center of Western Wisconsin, New Richmond, Wisconsin
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin
Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin
Ascension Mercy Hospital, Oshkosh, Wisconsin
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin
Ascension All Saints Hospital, Racine, Wisconsin
Aurora Cancer Care-Racine, Racine, Wisconsin
Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin
HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin
Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin
Sheboygan Physicians Group, Sheboygan, Wisconsin
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin
Essentia Health-Spooner Clinic, Spooner, Wisconsin
Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin
Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin
Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin
Aurora Medical Center in Summit, Summit, Wisconsin
Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin
Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin
Aspirus Regional Cancer Center, Wausau, Wisconsin
Ascension Medical Group Southeast Wisconsin - Mayfair Road, Wauwatosa, Wisconsin
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin
Aurora West Allis Medical Center, West Allis, Wisconsin
Marshfield Medical Center - Weston, Weston, Wisconsin
Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin
Cheyenne Regional Medical Center-West, Cheyenne, Wyoming
Billings Clinic-Cody, Cody, Wyoming
Welch Cancer Center, Sheridan, Wyoming
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta
Cross Cancer Institute, Edmonton, Alberta
BCCA-Fraser Valley Cancer Centre, Surrey, British Columbia
BCCA-Vancouver Cancer Centre, Vancouver, British Columbia
Atlantic Health Sciences Corporation-Saint John Regional Hospital, Saint John, New Brunswick
Kingston Health Sciences Centre, Kingston, Ontario
Niagara Health System-Saint Catharines General, Saint Catharines, Ontario
Thunder Bay Regional Health Science Centre, Thunder Bay, Ontario
University Health Network-Princess Margaret Hospital, Toronto, Ontario
PEI Cancer Treatment Centre-Queen Elizabeth Hospital, Charlottetown, Prince Edward Island
The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec
CHA Hopital L'Enfant-Jesus, Quebec City, Quebec
FHP Health Center-Guam, Tamuning, Not set
Conditions: Lung Non-Squamous Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
Recruiting
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type 1. Selumetinib works by blocking some of the enzymes needed for cell growth and may kill tumor cells. Carboplatin and vincristine are chemotherapy drugs... Read More
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type 1. Selumetinib works by blocking some of the enzymes needed for cell growth and may kill tumor cells. Carboplatin and vincristine are chemotherapy drugs that work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. The overall goal of this study is to see if selumetinib works just as well as the standard treatment of CV for patients with LGG. Another goal of this study is to compare the effects of selumetinib versus CV in subjects with LGG to find out which is better. Additionally, this trial will also examine if treatment with selumetinib improves the quality of life for subjects who take it. Read Less
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/29/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +131 locations
Children's Hospital of Alabama, Birmingham, Alabama
Banner Children's at Desert, Mesa, Arizona
Phoenix Childrens Hospital, Phoenix, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Loma Linda University Medical Center, Loma Linda, California
Miller Children's and Women's Hospital Long Beach, Long Beach, California
Children's Hospital Los Angeles, Los Angeles, California
Cedars Sinai Medical Center, Los Angeles, California
Mattel Children's Hospital UCLA, Los Angeles, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Lucile Packard Children's Hospital Stanford University, Palo Alto, California
Rady Children's Hospital - San Diego, San Diego, California
UCSF Medical Center-Mission Bay, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
Connecticut Children's Medical Center, Hartford, Connecticut
Yale University, New Haven, Connecticut
Alfred I duPont Hospital for Children, Wilmington, Delaware
Children's National Medical Center, Washington, District of Columbia
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Nicklaus Children's Hospital, Miami, Florida
AdventHealth Orlando, Orlando, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Nemours Children's Clinic - Pensacola, Pensacola, Florida
Sacred Heart Hospital, Pensacola, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Lurie Children's Hospital-Chicago, Chicago, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Riley Hospital for Children, Indianapolis, Indiana
Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana
Blank Children's Hospital, Des Moines, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Norton Children's Hospital, Louisville, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Maine Children's Cancer Program, Scarborough, Maine
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Walter Reed National Military Medical Center, Bethesda, Maryland
Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Corewell Health Children's, Royal Oak, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Morristown Medical Center, Morristown, New Jersey
Albany Medical Center, Albany, New York
Roswell Park Cancer Institute, Buffalo, New York
NYU Langone Hospital - Long Island, Mineola, New York
The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
State University of New York Upstate Medical University, Syracuse, New York
New York Medical College, Valhalla, New York
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
East Carolina University, Greenville, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Broadway Medical Center, Fargo, North Dakota
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Rainbow Babies and Childrens Hospital, Cleveland, Ohio
Nationwide Children's Hospital, Columbus, Ohio
Dayton Children's Hospital, Dayton, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Oregon Health and Science University, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Penn State Children's Hospital, Hershey, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Dell Children's Medical Center of Central Texas, Austin, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
El Paso Children's Hospital, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Covenant Children's Hospital, Lubbock, Texas
UMC Cancer Center / UMC Health System, Lubbock, Texas
Children's Hospital of San Antonio, San Antonio, Texas
Methodist Children's Hospital of South Texas, San Antonio, Texas
University of Texas Health Science Center at San Antonio, San Antonio, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Vermont and State Agricultural College, Burlington, Vermont
Children's Hospital of The King's Daughters, Norfolk, Virginia
VCU Massey Comprehensive Cancer Center, Richmond, Virginia
Carilion Children's, Roanoke, Virginia
Seattle Children's Hospital, Seattle, Washington
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
Madigan Army Medical Center, Tacoma, Washington
West Virginia University Healthcare, Morgantown, West Virginia
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Children's Hospital of Wisconsin, Milwaukee, Wisconsin
British Columbia Children's Hospital, Vancouver, British Columbia
Janeway Child Health Centre, Saint John's, Newfoundland and Labrador
IWK Health Centre, Halifax, Nova Scotia
The Montreal Children's Hospital of the MUHC, Montreal, Quebec
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set
HIMA San Pablo Oncologic Hospital, Caguas, Not set
Conditions: Low Grade Glioma, Low Grade Astrocytoma, Metastatic Low Grade Astrocytoma, Metastatic Low Grade Glioma
Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
Recruiting
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer (NSCLC). Participants in this study have NSCLC that has continued to progress on prior treatment with EGFR tyrosine kinase inhibitors (TKIs).
The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pe... Read More
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer (NSCLC). Participants in this study have NSCLC that has continued to progress on prior treatment with EGFR tyrosine kinase inhibitors (TKIs).
The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pemetrexed and carboplatin) in regard to progression-free survival (PFS) and overall survival (OS). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2025
Locations: Kaiser Permanente - Oakland ( Site 0054), Oakland, California +151 locations
Kaiser Permanente - Oakland ( Site 0054), Oakland, California
Kaiser Permanente - Roseville ( Site 0055), Roseville, California
Kaiser Permanente - San Francisco ( Site 0056), San Francisco, California
Kaiser Permanente - Santa Clara ( Site 0057), Santa Clara, California
Kaiser Permanente-Kaiser Permanente ( Site 0036), Vallejo, California
Kaiser Permanente - Walnut Creek ( Site 0058), Walnut Creek, California
Mid Florida Hematology and Oncology Center ( Site 0005), Orange City, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0003), Marietta, Georgia
University of Michigan ( Site 0009), Ann Arbor, Michigan
Cox Medical Center North - Cox Medical Center/ Hematology/Medical Oncology ( Site 0051), Springfield, Missouri
Astera Cancer Care ( Site 0032), East Brunswick, New Jersey
Stony Brook University-Cancer Center ( Site 0038), Stony Brook, New York
Sanford Fargo Medical Center ( Site 0028), Fargo, North Dakota
Sanford Cancer Center ( Site 0024), Sioux Falls, South Dakota
Millennium Research & Clinical Development ( Site 0035), Houston, Texas
Clinica Adventista Belgrano-Oncology ( Site 0315), Caba., Buenos Aires
Instituto Alexander Fleming ( Site 0307), Ciudad Autónoma de Buenos Aires, Buenos Aires
Hospital Británico de Buenos Aires-Oncology ( Site 0304), Ciudad autónoma de Buenos Aires, Caba
Centro Privado de RMI Río Cuarto S.A. II ( Site 0310), Río Cuarto, Cordoba
Instituto de Oncología de Rosario ( Site 0301), Rosario, Santa Fe
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0303), La Rioja, Not set
Cross Cancer Institute ( Site 0201), Edmonton, Alberta
Waterloo Regional Health Network (WRHN) ( Site 0207), Kitchener, Ontario
Princess Margaret Cancer Centre ( Site 0203), Toronto, Ontario
McGill University Health Centre ( Site 0204), Montréal, Quebec
Anhui Provincial Cancer Hospital ( Site 3132), Hefei, Anhui
Beijing Cancer hospital ( Site 3100), Beijing, Beijing
Beijing Peking Union Medical College Hospital-pneumology department ( Site 3107), Beijing, Beijing
Chongqing University Cancer Hospital-Medical Oncology ( Site 3128), Chongqing, Chongqing
Fujian Cancer Hospital ( Site 3124), Fuzhou, Fujian
The First Affiliated hospital of Xiamen University ( Site 3125), XiaMen, Fujian
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 3102), Guangzhou, Guangdong
Guangxi Medical University Affiliated Tumor Hospital-Respiratory Oncology ( Site 3103), Nanning, Guangxi
Harbin Medical University Cancer Hospital ( Site 3109), Harbin, Heilongjiang
Henan Cancer Hospital ( Site 3105), Zhengzhou, Henan
Tongji Hospital Tongji Medical,Science & Technology ( Site 3121), Wuhan, Hubei
Hubei Cancer Hospital ( Site 3122), Wuhan, Hubei
The Second Xiangya Hospital of Central South University-Oncology ( Site 3104), Changsha, Hunan
Nanjing Drum Tower Hospital JiangBei International Branch Hospital ( Site 3117), Nanjing, Jiangsu
The First Affiliated Hospital of Soochow University-Respiratory Department ( Site 3118), Suzhou, Jiangsu
The Second Affiliated Hospital of Nanchang University ( Site 3119), Nanchang, Jiangxi
The Second Affiliated Hospital of Xi'an Jiaotong University ( Site 3130), XI An, Shaanxi
Jinan Central Hospital ( Site 3113), Jinan, Shandong
Shandong Cancer Hospital ( Site 3112), Jinan, Shandong
Zhongshan Hospital of Fudan University ( Site 3133), Shanghai, Shanghai
Shanxi Cancer Hospital ( Site 3114), Taiyuan, Shanxi
West China Hospital, Sichuan University ( Site 3126), Cheng Du, Sichuan
Sichuan Cancer hospital. ( Site 3127), Chengdu, Sichuan
The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 3101), Hangzhou, Zhejiang
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 3106), Hangzhou, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 3120), Wenzhou, Zhejiang
Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 0601), Valledupar, Cesar
IMAT S.A.S ( Site 0602), Monteria, Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0600), Bogota, Distrito Capital De Bogota
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 0606), Bogota, Distrito Capital De Bogota
Oncologos del Occidente ( Site 0604), Pereira., Risaralda
Fundacion Valle del Lili- CIC-Oncology CIC ( Site 0605), Cali, Valle Del Cauca
Nouvel Hôpital Civil (NHC) ( Site 1302), Strasbourg, Alsace
Clinique Clairval ( Site 1306), Marseille, Bouches-du-Rhone
Gustave Roussy ( Site 1303), Villejuif, Ile-de-France
Hopitaux Universitaires Paris Centre-Hopital Cochin-Unité d'Oncologie Thoracique ( Site 1304), Paris, Not set
All India Institute of Medical Sciences-Department of medical oncology ( Site 3303), New Delhi, Delhi
Indraprastha Apollo Hospitals-APOLLO RESEARCH INNOVATION ( Site 3301), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre ( Site 3300), New Delhi, Delhi
Artemis hospital ( Site 3307), Gurugram, Haryana
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 3302), Mumbai, Maharashtra
Istituto Europeo di Oncologia IRCCS-Divisione di Oncologia Toracica ( Site 1803), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1800), Milan, Lombardia
Instituto Tumori Giovanni Paolo II-SSD Oncologia Medica per la Patologia Toracica ( Site 1802), Bari, Puglia
Azienda Ospedaliera Universitaria Careggi-SOD ONCOLOGIA MEDICA ( Site 1804), Firenze, Toscana
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1801), Roma, Not set
Fujita Health University Hospital ( Site 3409), Toyoake, Aichi
Ehime University Hospital ( Site 3411), Toon, Ehime
National Hospital Organization Kyushu Cancer Center ( Site 3401), Fukuoka,, Fukuoka
Gunma Prefectural Cancer Center ( Site 3413), Ota, Gunma
Kanazawa University Hospital ( Site 3402), Kanazawa, Ishikawa
St. Marianna University Hospital ( Site 3415), Kawasaki, Kanagawa
Kanagawa Cancer Center ( Site 3416), Yokohama, Kanagawa
Miyagi Cancer Center ( Site 3406), Natori, Miyagi
Kansai Medical University Hospital ( Site 3414), Hirakata, Osaka
Saitama Prefectural Cancer Center ( Site 3417), Kitaadachi-gun, Saitama
Shizuoka Cancer Center ( Site 3405), Sunto-gun, Shizuoka
National Cancer Center Hospital ( Site 3408), Chuo, Tokyo
Toho University Omori Medical Center ( Site 3407), Ota, Tokyo
Kyushu University Hospital ( Site 3400), Fukuoka, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 3419), Hiroshima, Not set
Niigata Cancer Center Hospital ( Site 3403), Niigata, Not set
Okayama University Hospital ( Site 3404), Okayama, Not set
Osaka International Cancer Institute ( Site 3410), Osaka, Not set
Osaka Metropolitan University Hospital ( Site 3412), Osaka, Not set
Chungbuk National University Hospital ( Site 3804), Cheongju-si, Chungbuk
National Cancer Center ( Site 3803), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital ( Site 3807), Seongnam, Kyonggi-do
The Catholic University Of Korea St. Vincent's Hospital ( Site 3800), Suwon-si, Kyonggi-do
Ajou University Hospital ( Site 3813), Suwon, Kyonggi-do
Pusan National University Yangsan Hospital ( Site 3802), Pusan, Kyongsangnam-do
Pusan National University Hospital ( Site 3805), Busan, Pusan-Kwangyokshi
Keimyung University Dongsan Hospital CRC room 1 ( Site 3814), Daegu, Taegu-Kwangyokshi
Chungnam national university hospital ( Site 3806), Jung-gu, Taejon-Kwangyokshi
The Catholic University of Korea, Eunpyeong St. Mary's Hospital ( Site 3812), Seoul, Not set
Asan Medical Center ( Site 3810), Seoul, Not set
Samsung Medical Center ( Site 3811), Seoul, Not set
Korea University Guro Hospital ( Site 3808), Seoul, Not set
University Malaya Medical Centre ( Site 3507), Lembah Pantai, Kuala Lumpur
National Cancer Institute-Radiotherapy and Oncology ( Site 3504), Putrajaya, Kuala Lumpur
Hospital Tengku Ampuan Afzan ( Site 3506), Kuantan, Pahang
Hospital Pulau Pinang-Oncology, radiotherapy and palliat ( Site 3501), George Town, Pulau Pinang
Sarawak General Hospital-Radiotherapy Unit ( Site 3508), Kuching, Sarawak
Arké SMO S.A. de C.V. ( Site 0706), Mexico, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0700), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0705), Monterrey, Nuevo Leon
Centro de Investigacion Clinica de Oaxaca ( Site 0704), Oaxaca de Juarez, Oaxaca
Oaxaca Site Management Organization S.C. ( Site 0701), Oaxaca, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kujawsko-pomorskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warszawa, Mazowieckie
Bialostockie Centrum Onkologii ( Site 2010), Bialystok, Podlaskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-II Klinika Radioterapi i Chemioterapii ( Site 2002), Gliwice, Slaskie
Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 2321), LHospitalet de Llobregat, Barcelona
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 2322), Santiago de compostela, La Coruna
Hospital Universitario Juan Ramon Jimenez-Oncología Medica ( Site 2323), Huelva, Not set
Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 2324), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 2401), Stockholm, Stockholms Lan
National Cheng Kung University Hospital ( Site 3901), Tainan City, Tainan
Chi Mei Hospital - Liouying Branch ( Site 3909), Tainan City, Tainan
National Taiwan University Cancer Center (NTUCC) ( Site 3907), Taipei City, Taipei
Changhua Christian Hospital ( Site 3904), Changhua, Not set
National Taiwan University Hospital - Hsinchu branch ( Site 3900), Hsinchu, Not set
Chang Gung Memorial Hospital at Kaohsiung ( Site 3905), Kaohsiung, Not set
Far Eastern Memorial Hospital ( Site 3912), New Taipei, Not set
Taichung Veterans General Hospital-Chest ( Site 3910), Taichung, Not set
National Taiwan University Hospital-Oncology ( Site 3908), Taipei, Not set
Mackay Memorial Hospital-Chest Medicine ( Site 3902), Taipei, Not set
Taipei Medical University Hospital ( Site 3903), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 3911), Taoyuan, Not set
Maharaj Nakorn Chiang Mai Hospital ( Site 4005), Muang, Chiang Mai
Faculty of Medicine - Khon Kaen University ( Site 4002), Muang, Khon Kaen
Faculty of Medicine Siriraj Hospital ( Site 4004), Bangkok, Krung Thep Maha Nakhon
Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 4006), Dusit, Krung Thep Maha Nakhon
Ramathibodi Hospital ( Site 4001), Ratchathewi, Krung Thep Maha Nakhon
Lampang Cancer Hospital ( Site 4000), Mueang Lampang, Lampang
Songklanagarind hospital ( Site 4003), HatYai, Songkhla
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 2504), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 2501), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 2505), Ankara, Not set
Ankara Bilkent Şehir Hastanesi ( Site 2500), Ankara, Not set
I.E.U. Medical Point Hastanesi-Oncology ( Site 2503), Izmir, Not set
Hanoi Oncology Hospital ( Site 4198), Hanoi, Ha Noi
K Hospital - National Cancer Hospital ( Site 4193), Hanoi, Ha Noi
National Lung Hospital-Oncology Department ( Site 4194), Hanoi, Ha Noi
Thong Nhat Hospital ( Site 4192), Tan Binh District, Ho Chi Minh
Cho Ray Hospital ( Site 4190), Ho Chi Minh, Not set
Ho Chi Minh City Oncology Hospital - Tan Phu Ward ( Site 4191), Ho Chi Minh, Not set
Conditions: Non-small Cell Lung Cancer (NSCLC)
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