Carboplatin Treatment Options in Canada

A collection of 336 research studies where Carboplatin is the interventional treatment. These studies are located in the Canada . Carboplatin is used for conditions such as Non-Small Cell Lung Cancer, Ovarian Cancer and Lung Cancer.

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

NCT06103864

Recruiting

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with investigator's choice chemotherapy in combination with pembrolizumab in participants with PD-L1 positive locally recurrent inoperable or metastatic TNBC.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/28/2025

Locations: Research Site, Daphne, Alabama +299 locations

Research Site, Daphne, Alabama

Research Site, Springdale, Arkansas

Research Site, Duarte, California

Research Site, Glendale, California

Research Site, Sacramento, California

Research Site, Santa Rosa, California

Research Site, Aurora, Colorado

Research Site, New Haven, Connecticut

Research Site, Jacksonville, Florida

Research Site, Miami, Florida

Research Site, Palm Bay, Florida

Research Site, Plantation, Florida

Research Site, Atlanta, Georgia

Research Site, Honolulu, Hawaii

Research Site, Chicago, Illinois

Research Site, Decatur, Illinois

Research Site, Elmhurst, Illinois

Research Site, Naperville, Illinois

Research Site, New Albany, Indiana

Research Site, Des Moines, Iowa

Research Site, Lexington, Kentucky

Research Site, Louisville, Kentucky

Research Site, Baton Rouge, Louisiana

Research Site, Baltimore, Maryland

Research Site, Columbia, Maryland

Research Site, Boston, Massachusetts

Research Site, Worcester, Massachusetts

Research Site, Detroit, Michigan

Research Site, Grand Rapids, Michigan

Research Site, Saint Paul, Minnesota

Research Site, Hattiesburg, Mississippi

Research Site, Saint Louis, Missouri

Research Site, Albuquerque, New Mexico

Research Site, Albany, New York

Research Site, New York, New York

Research Site, Stony Brook, New York

Research Site, Cincinnati, Ohio

Research Site, Cleveland, Ohio

Research Site, York, Pennsylvania

Research Site, Providence, Rhode Island

Research Site, Chattanooga, Tennessee

Research Site, Nashville, Tennessee

Research Site, Dallas, Texas

Research Site, El Paso, Texas

Research Site, Flower Mound, Texas

Research Site, Fort Worth, Texas

Research Site, Houston, Texas

Research Site, Kingwood, Texas

Research Site, McKinney, Texas

Research Site, Sugar Land, Texas

Research Site, Charlottesville, Virginia

Research Site, Fairfax, Virginia

Research Site, Midlothian, Virginia

Research Site, Norfolk, Virginia

Research Site, Roanoke, Virginia

Research Site, Tacoma, Washington

Research Site, Madison, Wisconsin

Research Site, Buenos Aires, Not set

Research Site, Caba, Not set

Research Site, Ciudad Autonoma Bs As, Not set

Research Site, Rosario, Not set

Research Site, San Nicolas de Los Arroyos, Not set

Research Site, Camperdown, Not set

Research Site, Darlinghurst, Not set

Research Site, Heidelberg, Not set

Research Site, Melbourne, Not set

Research Site, Nedlands, Not set

Research Site, Waratah, Not set

Research Site, Barretos, Not set

Research Site, Curitiba, Not set

Research Site, Florianópolis, Not set

Research Site, Goiânia, Not set

Research Site, Itajai, Not set

Research Site, Porto Alegre, Not set

Research Site, Recife, Not set

Research Site, Sao Paulo, Not set

Research Site, São Paulo, Not set

Research Site, Teresina, Not set

Research Site, Barrie, Ontario

Research Site, Hamilton, Ontario

Research Site, Toronto, Ontario

Research Site, Greenfield Park, Quebec

Research Site, Montreal, Quebec

Research Site, Montréal, Quebec

Research Site, Regina, Saskatchewan

Research Site, Saskatoon, Saskatchewan

Research Site, Quebec, Not set

Research Site, Beijing, Not set

Research Site, Bengbu, Not set

Research Site, Changchun, Not set

Research Site, Changsha, Not set

Research Site, Chengdu, Not set

Research Site, Chongqing, Not set

Research Site, Fuzhou, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Harbin, Not set

Research Site, Hefei, Not set

Research Site, Ji Nan, Not set

Research Site, Nanchang, Not set

Research Site, Nanjing, Not set

Research Site, Nanning, Not set

Research Site, Shandong, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Tianjin, Not set

Research Site, Wenzhou, Not set

Research Site, Wuhan, Not set

Research Site, Xi'an, Not set

Research Site, Xiamen, Not set

Research Site, Xintai, Not set

Research Site, Xuzhou, Not set

Research Site, Zhengzhou, Not set

Research Site, Lille, Not set

Research Site, Lyon, Not set

Research Site, Paris, Not set

Research Site, Saint Herblain Cedex, Not set

Research Site, Toulouse Cedex 9, Not set

Research Site, Vandoeuvre-lès-nancy, Not set

Research Site, Villejuif, Not set

Research Site, Düsseldorf, Not set

Research Site, Essen, Not set

Research Site, Georgsmarienhütte, Not set

Research Site, Hamburg, Not set

Research Site, Hannover, Not set

Research Site, Heidelberg, Not set

Research Site, Heilbronn, Not set

Research Site, Leipzig, Not set

Research Site, Hong Kong, Not set

Research Site, Calicut, Not set

Research Site, Chennai, Not set

Research Site, Kochi, Not set

Research Site, Kolkata, Not set

Research Site, Marg Jaipur, Not set

Research Site, Mohali, Not set

Research Site, Mysuru, Not set

Research Site, Nagpur, Not set

Research Site, Nashik, Not set

Research Site, New Delhi, Not set

Research Site, Pondicherry, Not set

Research Site, Surat, Not set

Research Site, Thiruvananthapuram, Not set

Research Site, Vadodara, Not set

Research Site, Vishakapatnam, Not set

Research Site, Bergamo, Not set

Research Site, Empoli, Not set

Research Site, Milano, Not set

Research Site, Milan, Not set

Research Site, Modena, Not set

Research Site, Napoli, Not set

Research Site, Padova, Not set

Research Site, Reggio Emilia, Not set

Research Site, Roma, Not set

Research Site, Rozzano, Not set

Research Site, Akashi-shi, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Chiba-shi, Not set

Research Site, Chuo-ku, Not set

Research Site, Fukuoka-shi, Not set

Research Site, Fukushima-shi, Not set

Research Site, Gifu-shi, Not set

Research Site, Hidaka-shi, Not set

Research Site, Hiroshima-shi, Not set

Research Site, Isehara-shi, Not set

Research Site, Kamogawa-shi, Not set

Research Site, Kashiwa, Not set

Research Site, Kitaadachi-gun, Not set

Research Site, Koto-ku, Not set

Research Site, Kumamoto-shi, Not set

Research Site, Kurume-shi, Not set

Research Site, Matsuyama-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Niigata-shi, Not set

Research Site, Nishinomiya-shi, Not set

Research Site, Okayama-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Ota-shi, Not set

Research Site, Sapporo-shi, Not set

Research Site, Sendai-shi, Not set

Research Site, Shinagawa-ku, Not set

Research Site, Shinjuku-ku, Not set

Research Site, Tsu-shi, Not set

Research Site, Tsukuba, Not set

Research Site, Yokohama-shi, Not set

Research Site, Busan, Not set

Research Site, Daegu, Not set

Research Site, Goyang-si, Not set

Research Site, Seongnam-si, Not set

Research Site, Seoul, Not set

Research Site, CD Mexico, Not set

Research Site, Guadalajara, Not set

Research Site, Mexico City, Not set

Research Site, Mexico, Not set

Research Site, México, Not set

Research Site, Tuxtla Gutierrez, Not set

Research Site, Bacolod, Not set

Research Site, Cebu City, Not set

Research Site, Manila, Not set

Research Site, Muntinlupa City, Not set

Research Site, Quezon City, Not set

Research Site, San Juan, Not set

Research Site, Białystok, Not set

Research Site, Bydgoszcz, Not set

Research Site, Gdańsk, Not set

Research Site, Gdynia, Not set

Research Site, Konin, Not set

Research Site, Kraków, Not set

Research Site, Legnica, Not set

Research Site, Lublin, Not set

Research Site, Przemysl, Not set

Research Site, Warszawa, Not set

Research Site, Wroclaw, Not set

Research Site, Łódź, Not set

Research Site, Singapore, Not set

Research Site, Cape Town, Not set

Research Site, Johannesburg, Not set

Research Site, Paarl, Not set

Research Site, Pretoria, Not set

Research Site, Barcelona, Not set

Research Site, Granada, Not set

Research Site, Hospitalet deLlobregat, Not set

Research Site, Madrid, Not set

Research Site, Pamplona, Not set

Research Site, Santander, Not set

Research Site, Hsinchu, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Tainan, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Bangkok, Not set

Research Site, Chiang Mai, Not set

Research Site, Dusit, Not set

Research Site, Khon Kaen, Not set

Research Site, Songkhla, Not set

Research Site, Ankara, Not set

Research Site, Besevler Ankara, Not set

Research Site, Izmir, Not set

Research Site, Küçükçekmece, Not set

Research Site, Samsun, Not set

Research Site, Cardiff, Not set

Research Site, Chelsea, Not set

Research Site, Leicester, Not set

Research Site, Liverpool, Not set

Research Site, London, Not set

Research Site, Oxford, Not set

Research Site, Surrey, Not set

Research Site, Sutton, Not set

Research Site, Taunton, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh City, Not set

Research Site, Vinh, Not set

Conditions: Breast Cancer

Learn More ›

Volrustomig Priming Regimens Exploratory Phase II Platform Study

NCT06448754

Recruiting

Purpose of this study is to assess the safety, tolerability, pharmacokinetics, immunogenicity, and antitumor activity of volrustomig in combination with other anticancer drugs in participants with specified solid tumors.

Gender:

ALL

Ages:

Between 18 years and 130 years

Trial Updated:

04/24/2025

Locations: Research Site, Los Angeles, California +74 locations

Research Site, Los Angeles, California

Research Site, Grand Junction, Colorado

Research Site, Wheat Ridge, Colorado

Research Site, Baltimore, Maryland

Research Site, Detroit, Michigan

Research Site, Chapel Hill, North Carolina

Research Site, Tacoma, Washington

Research Site, Montreal, Quebec

Research Site, Beijing, Not set

Research Site, Hangzhou, Not set

Research Site, Jinan, Not set

Research Site, Yantai, Not set

Research Site, Zhengzhou City, Not set

Research Site, Bois Guillaume, Not set

Research Site, Caen Cedex, Not set

Research Site, Créteil, Not set

Research Site, Dijon, Not set

Research Site, Montpellier, Not set

Research Site, Batumi, Not set

Research Site, Tbilisi, Not set

Research Site, Athens, Not set

Research Site, Elaiones, Not set

Research Site, Peiraias, Not set

Research Site, Thessaloniki, Not set

Research Site, Genoa, Not set

Research Site, Meldola, Not set

Research Site, Milano, Not set

Research Site, Napoli, Not set

Research Site, Orbassano, Not set

Research Site, Perugia, Not set

Research Site, Rozzano, Not set

Research Site, Udine, Not set

Research Site, Verona, Not set

Research Site, Seongnam, Not set

Research Site, Seoul, Not set

Research Site, Suwon, Not set

Research Site, Kuala Lumpur, Not set

Research Site, Kuching, Not set

Research Site, Perai, Not set

Research Site, Lisboa, Not set

Research Site, Porto, Not set

Research Site, Cluj-Napoca, Not set

Research Site, Craiova, Not set

Research Site, Floresti, Not set

Research Site, Belgrade, Not set

Research Site, Kragujevac, Not set

Research Site, Sremska Kamenica, Not set

Research Site, Alcorcón, Not set

Research Site, Barcelona, Not set

Research Site, La Coruna, Not set

Research Site, Madrid, Not set

Research Site, Málaga, Not set

Research Site, Pamplona, Not set

Research Site, Santander, Not set

Research Site, Santiago de Compostela, Not set

Research Site, Valencia, Not set

Research Site, Basel, Not set

Research Site, Genève 14, Not set

Research Site, Lausanne, Not set

Research Site, Winterthur, Not set

Research Site, Zürich, Not set

Research Site, Changhua City, Not set

Research Site, New Taipei, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Conditions: Non-small Cell Lung Cancer

Learn More ›

A Study of SEA-CD40 Given With Other Drugs in Cancers

NCT04993677

Completed

This trial is being done to see if an experimental drug (SEA-CD40) works when it's given with other cancer drugs to treat some types of cancer. It will also study side effects from the drug. There are 2 parts in this trial. In one part, participants have melanoma that has come back after treatment or can't be removed by surgery. Participants in this part will get SEA-CD40 and pembrolizumab. In the other part, participants have non-small cell lung cancer (NSCLC) that has spread through their bod... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/23/2025

Locations: Highlands Oncology Group, Springdale, Arkansas +28 locations

Highlands Oncology Group, Springdale, Arkansas

The Angeles Clinic and Research Institute, Los Angeles, California

California Pacific Medical Center Research Institute/Sutter Medical Centre, San Francisco, California

University of California at San Francisco, San Francisco, California

Florida Cancer Specialists - South Region, Fort Myers, Florida

Florida Cancer Specialists - North Region, Saint Petersburg, Florida

University Cancer & Blood Center, LLC, Athens, Georgia

Rush University Medical Center, Chicago, Illinois

Community Health Network, Indianapolis, Indiana

American Oncology Networks LLC, Baton Rouge, Louisiana

Allina Health Cancer Institute, Minneapolis, Minnesota

University of Minnesota, Minneapolis, Minnesota

Regions Cancer Care Center, Saint Paul, Minnesota

Morristown Medical Center/ Carol G. Simon Cancer Center, Morristown, New Jersey

Duke University Medical Center, Durham, North Carolina

Gabrail Cancer Center Research, LLC, Canton, Ohio

Cleveland Clinic - Taussig Cancer Institute, Cleveland, Ohio

Kaiser Permanente Oregon, Portland, Oregon

Thomas Jefferson University, Philadelphia, Pennsylvania

Tennessee Oncology-Nashville/Sarah Cannon Research Institute, Nashville, Tennessee

University of Texas Southwestern/Simmons Cancer Center, Dallas, Texas

MD Anderson Cancer Center / University of Texas, Houston, Texas

Carbone Cancer Center / University of Wisconsin, Madison, Wisconsin

CHU de Quebec-Universite Laval, Quebec, Not set

Hopital Foch, Suresnes, Other

Universitatsklinikum Heidelberg, Heidelberg, Other

START Madrid-CIOCC_Hospital HM Sanchinarro, Madrid, Other

Hospital Clinico Universitario de Valencia, Valencia, Other

Karolinska University Hospital, Stockholm, Other

Conditions: Melanoma, Carcinoma, Non-Small- Cell Lung

Learn More ›

TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

NCT04129502

Active Not Recruiting

The purpose of this study is to compare effectiveness of TAK-788 as first-line treatment with that of platinum-based chemotherapy in participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors has epidermal growth factor receptor (EGFR) exon 20 insertion mutations. Participants will be randomly assigned to one of the two treatment groups- TAK-788 group or Platinum-based chemotherapy group. Participants will receive TAK-788 orally and pemetrexed/cisplatin or... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/21/2025

Locations: City of Hope National Medical Center, Long Beach, California +133 locations

City of Hope National Medical Center, Long Beach, California

University of California Irvine, Orange, California

Stanford University, Palo Alto, California

AdventHealth, Orlando, Florida

Northwestern University, Chicago, Illinois

University of Maryland Greenebaum Cancer Center, Baltimore, Maryland

Beth Israel Deaconess Medical Center - 330 Brookline Ave, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Massachusetts General Hospital, Boston, Massachusetts

Sarah Cannon Cancer Center, Nashville, Tennessee

University of Virginia Health System, Charlottesville, Virginia

GenesisCare North Shore, St Leonards, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Flinders Medical Centre, Bedford Park, South Australia

Klinik Floridsdorf, Wien, Not set

Cliniques Universitaires Saint-Luc, Bruxelles, Brussels

Grand Hopital de Charleroi asbl, Charleroi, Hainaut

AZ Sint-Lucas, Aalst, Oost-Vlaanderen

British Columbia Cancer Agency, Vancouver, British Columbia

William Osler Health System, Brampton, Ontario

Princess Margaret Hospital, Toronto, Ontario

Hopital Du Sacre Coeur de Montreal, Montreal, Quebec

Beijing Cancer Hospital - PPDS, Beijing, Beijing

Henan Cancer Hospital, Zhengzhou, Henan

Jilin Cancer Hospital, Changchun, Jilin

Beijing Cancer Hospital - PPDS, Beijing, Not set

Beijing Chest Hospital, Capital Medical Univerity, Beijing, Not set

Icahn School of Medicine at Mount Sinai, Beijing, Not set

Sichuan Cancer Hospital & Institute, Chengdu, Not set

Guangdong Provincial People's Hospital, Guangzhou, Not set

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Not set

Harbin Medical University Tumor Hospital, Harbin, Not set

Shanghai East Hospital, Shanghai, Not set

Hubei Cancer Hospital, Wuhan, Not set

Centre Francois Baclesse, Caen, Calvados

CHU de Nantes - Hoptal Nord Laennec, Nantes, Loire-Atlantique

Hopital Calmette, Lille, Nord

Centre Leon Berard, Lyon, Rhone

Institut Gustave Roussy, Villejuif, Val-de-Marne

CHU de Grenoble, Grenoble, Not set

Hopital Nord AP-HM, Marseille, Not set

CRLC Val d'Aurelle - Paul Lamarque, Montpellier, Not set

Hopital Tenon, Paris, Not set

Nouvel Hopital Civil, Strasbourg, Not set

Hopital Larrey, Toulouse, Not set

Thoraxklinik-Heidelberg gGmbH, Heidelberg, Baden-Wurttemberg

LMU Klinikum der Universitat Munchen, Munchen, Bayern

University Clinic Regensburg, Regensburg, Bayern

Universitatsklinikum Frankfurt, Frankfurt am Main, Hessen

Pius Hospital Oldenburg, Oldenburg, Niedersachsen

Helios Klinikum Emil Von Behring, Berlin, Not set

Sotiria Chest Hospital of Athens, Athens, Attiki

Bioclinic Thessaloniki (Galinos clinic), Thessaloniki, Not set

Princess Margaret Hospital, Kowloon, Kowloon City

Pamela Youde Nethersole Eastern Hospital, Hong Kong, Not set

Queen Elizabeth Hospital (QEH), Hong Kong, Not set

Queen Mary Hospital - PPDS, Hong Kong, Not set

Tuen Mun Hospital, Hong Kong, Not set

Prince of Wales Hospital, Sha Tin, Not set

Soroka University Medical Centre, Beer Sheva, Not set

Sheba Medical Center - PPDS, Ramat Gan, Not set

AORN Dei Colli- Ospedale Monaldi Napoli, Napoli, Campania

Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l - PPDS, Meldola, Forli-Cesena

Istituto Nazionale Dei Tumori, Milano, Lombardia

Instituto Europeo Di Oncologia, Milano, Lombardia

Azienda Sanitaria Ospedaliera S Luigi Gonzaga, Orbassano, Piemonte

Centro Di Riferimento Oncologico, Aviano, Pordenone

Azienda Ospedaliero Universitaria Pisana, Pisa, Toscana

Azienda Ospedaliero Universitaria di Parma, Parma, Not set

Ospedale Santa Maria Delle Croci, Ravenna, Not set

Fujita Health University Hospital, Toyoake-Shi, Aiti

Ehime University Hospital, Matsuyama-Shi, Ehime

National Hospital Organization Hokkaido Cancer Center, Sapporo-Shi, Hokkaido

Kurume University Hospital, Kurume-Shi, Hukuoka

Kanagawa Cancer Center, Yokohama-Shi, Kanagawa

Saiseikai Kumamoto Hospital, Kumamoto-Shi, Kumamoto

Miyagi Cancer Center, Natori-Shi, Miyagi

Okayama University Hospital, Okayama-Shi, Okayama

Osaka International Cancer Institute, Chuo Ku, Osaka

Saitama Cancer Center, Komoro, Saitama

National Cancer Center Hospital East, Kashiwa-Shi, Tiba

The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Koto-Ku, Tokyo

Chungbuk National University Hospital, Cheongju-si, Chungcheongbugdo

Pusan National University Hospital, Busan, Not set

National Cancer Center, Goyang, Not set

Chonnam National University Hwasun Hospital, Jeongnam, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center - PPDS, Seoul, Not set

Samsung Medical Center PPDS, Seoul, Not set

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System - PPDS, Seoul, Not set

VU Medisch Centrum, Amsterdam, Noord-Holland

Centro Hospitalar do Porto Hospital de Santo Antonio, Santa Maria Da Feira, Aveiro

Hospital Cuf Porto, Vila Nova de Gaia, Porto

Centro Hospitalar de Lisboa Norte E.P.E Hospital Pulido Valente, Lisboa, Not set

Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe - PPDS, Porto, Not set

Centro Hospitalar de Sao Joao, E.P.E., Porto, Not set

GBUZ Saint Petersburg Clinical Research Center of Specialized Types of Care (Oncology), Saint Petersburg, Leningradskaya Oblast

LLC "EuroCityClinic", Saint Petersburg, Sankt-Peterburg

National Cancer Centre, Singapore, Not set

ICO lHospitalet Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona

Hospital Universitario A Coruna, A Coruna, Not set

Hospital General Universitario de Alicante, Alicante, Not set

Hospital Universitario Vall d'Hebron - PPDS, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

C.H. Regional Reina Sofia - PPDS, Cordoba, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz - PPDS, Madrid, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Karolinska Universitetssjukhuset Solna, Stockholm, Sodermanlands Lan

Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Not set

National Taiwan University Hospital - YunLin Branch, Douliu, Not set

Kaohsiung Medical University - Chung-Ho Memorial Hospital, Kaohsiung, Not set

E-DA hospital, Kaohsiung, Not set

Taichung Veterans General Hospital, Taichung City, Not set

Chi Mei Medical Center, Liouying, Tainan City, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Baskent University Medical Faculty Adana Practice and Research Center, Yuregir, Adana

T.C. Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Kadikoy, Istanbul

Ege University Medical Faculty, Bornova, Izmir

SAKARYA University Medical Faculty, Karaman, Sakarya

Hacettepe University Medical Faculty, Ankara, Not set

Trakya University Medical Faculty, Edirne, Not set

Municipal Non-profit Enterprise "City Clinical Hospital # 4" of Dnipro City Council - PPDS, Dnipropetrovsk, Dnipropetrovs'ka Oblast

Communal Non-profit Enterprise Regional Center of Oncology, Kharkiv, Kharkivs'ka Oblast

Private Enterprise Private Manufacturing Company Acinus, Kropyvnytskyi, Not set

University College London Hospitals (UCLH), London, London, City Of

Royal Marsden Hospital - Surrey, Sutton, Surrey

Clatterbridge Centre For Oncology, Bebington, Wirral

Leicester General Hospital, Leicester, Not set

The Christie NHS Foundation Trust - PPDS, Manchester, Not set

Conditions: Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

Learn More ›

A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer

NCT04194944

Active Not Recruiting

The reason for this study is to see if the study drug selpercatinib compared to a standard treatment is effective and safe in participants with rearranged during transfection (RET) fusion-positive non-squamous non-small cell lung cancer (NSCLC) that has spread to other parts of the body. Participants who are assigned to the standard treatment and discontinue due to progressive disease have the option to potentially crossover to selpercatinib.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/17/2025

Locations: Centro de Oncología e Investigación de Buenos Aires, Berazategui, Buenos Aires +195 locations

Centro de Oncología e Investigación de Buenos Aires, Berazategui, Buenos Aires

Fundacion CENIT para la Investigacion en Neurociencias, Caba, Buenos Aires

Clinica Viedma, Viedma, Río Negro

Alexander Fleming, Ciudad de Buenos Aires, Not set

Clínica El Castaño, San Juan, Not set

Chris O'Brien Lifehouse, Camperdown, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Westmead Hospital, Westmead, New South Wales

Monash Health, Clayton, Victoria

Peter MacCallum Cancer Centre, Melbourne, Victoria

St Vincent's Hospital, Melbourne, Victoria

Peninsula Oncology Centre, Frankston, Not set

UZ Brussel, Brussels, Bruxelles-Capitale, Région De

AZ Nikolaas, Sint Niklaas, Oost-Vlaanderen

UZ Leuven, Leuven, Vlaams-Brabant

AZ Delta, Roeselare, West Flanders

UZ Gent Hospital, Gent, Not set

AZ Sint-Maarten, Campus Leopoldstraat 2, Mechelen, Not set

CHU UCL Namur/Site Sainte Elisabeth, Namur, Not set

Núcleo de Oncologia da Bahia, Salvador, Bahia

Hospital de Cancer de Londrina, Londrina, Paraná

Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

Grupo COI - Clínicas Oncológicas Integradas, Rio de Janeiro, RJ

Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, Sao Paulo

Instituto D'Or de Pesquisa e Ensino (IDOR), Sao Paulo, SP

Instituto Nacional de Câncer - INCA, Rio de Janeiro, Not set

Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA, Rio de Janeiro, Not set

Hospital Sírio Libanês, Sao Paolo, Not set

Icesp - Instituto Do Câncer Do Estado de São Paulo, Sao Paulo, Not set

Hospital Sírio Libanês, São Paulo, Not set

Cross Cancer Institute, Edmonton, Alberta

Princess Margaret Cancer Centre, Toronto, Ontario

Beijing Cancer hospital, Beijing, Beijing

First affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong

The First Affiated Hospital Of Guangzhou Medical Collage, Guangzhou, Guangzhou

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

Wuhan Union Hospital, Wuhan, Hubei

Hunan Provincial People's Hospital, Changsha, Hunan

Hunan Cancer Hospital, Changsha, Hunan

Changzhou No.2 People's Hospital, Changzhou, Jiangsu

Jilin Cancer Hospital, Changchun, Jilin

Shanghai Pulmonary Hospital, Shanghai, Shanghai

West China Hospital of Sichuan University, Cheng Du, Sichuan

Xinjiang Medical University Cancer Hospital - Urumqi, Urumqi, Xinjiang

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

First Affiliated Hosp of College of Med, Zhejiang University, Hangzhou, Not set

Shanghai Chest Hospital, Shanghai, Not set

Fakultni nemocnice Olomouc, Olomouc, Not set

Nemocnice AGEL Ostrava - Vitkovice a.s., Ostrava - Vitkovice, Not set

Fakultni nemocnice Bulovka, Praha 8, Not set

Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone, Marseille, Bouches-du-Rhône

Institut Régional du Cancer Montpellier, Montpellier Cedex 5, Hérault

Chu Grenoble Alpes, La Tronche, Isère

Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne, Clermont-Ferrand, Puy-de-Dôme

Centre Leon Berard, Lyon, Rhône-Alpes

Hopitaux Universitaires Paris Centre-Hopital Cochin, Paris, Not set

Thoraxklinik-Heidelberg gGmbH, Heidelberg, Baden-Württemberg

Asklepios Fachkliniken München-Gauting, Gauting, Bayern

Klinikverbund Kempten-Oberallgäu, Immenstadt, Bayern

Franziskus-Hospital Harderberg, Georgsmarienhütte, Niedersachsen

Universitätsmedizin Göttingen, Göttingen, Niedersachsen

University Hospital of Cologne, Köln, Nordrhein-Westfalen

LungenClinic Grosshansdorf, Grosshansdorf, Schleswig-Holstein

Charite Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set

Sotiria Thoracic Diseases Hospital of Athens, Athens, Attikí

University General Hospital of Heraklion, Heraklion, Krítí

European Interbalkan Medical Center, Thessaloniki, Thessaloníki

G. Papanikolaou General Hospital, Thessaloniki, Thessaloníki

Hong Kong United Oncology Centre, Jordan, Kowloon

Prince of Wales Hospital, Shatin, Not set

Soroka Medical Center, Beer-Sheva, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Hadassah Medical Center, Jerusalem, Not set

Sheba Medical Center, Ramat Gan, Not set

Rambam Health Care Campus, Haifa, Ḥeifā

Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania

Ospedale Santa Maria delle Croci, Ravenna, Emilia-Romagna

Cro-Irccs, Aviano, Friuli-Venezia Giulia

Azienda Ospedaliera San Camillo Forlanini, Roma, Lazio

Fondazione Policlinico Universitario Agostino Gemelli, Roma, Lazio

Ospedale San Gerardo-ASST Monza, Monza, Lombardia

ASST Grande Ospedale Metropolitano Niguarda, Milan, Milano

Humanitas, Rozzano, Milano

Azienda Sanitaria Ospedaliera S Luigi Gonzaga, Orbassano, Torino

Azienda Ospedaliera San Giuseppe Moscati, Avellino, Not set

IRCCS - AOU di Bologna, Bologna, Not set

Azienda Ospedaliera Universitaria Pisana, Pisa, Not set

Istituto Nazionale Tumori Regina Elena, Roma, Not set

National Cancer Center Hospital East, Kashiwa, Chiba

National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido

Kanazawa University Hospital, Kanazawa, Ishikawa

Kanagawa cancer center, Yokohama, Kanagawa

Kindai University Hospital- Osakasayama Campus, Osaka Sayama-shi, Osaka

Tominaga Hospital, Nagaizumi, Shizuoka

National Cancer Center Hospital, Chuo-ku, Tokyo

Japanese Foundation for Cancer Research, Koto, Tokyo

Tottori University Hospital, Yonago, Tottori

Okayama University Hospital, Okayama, Not set

Osaka International Cancer Institute, Osaka, Not set

National Cancer Center, Goyang-si, Gyeonggi-do

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do

Gachon University Gil Medical Center, Incheon, Korea

Asan Medical Center, Seoul, Korea

Gyeongsang National University Hospital, Jin-ju-si, Kyǒngsangnam-do

Seoul National University Hospital, Seoul, Seoul, Korea

Boramae Medical Center, Dongjak-gu, Seoul-teukbyeolsi [Seoul]

Konyang University Hospital, Daejon, Not set

Samsung Medical Center, Seoul, Not set

Health Pharma Professional Research S.A. de C.V:, Mexico City, Federal District

Actualidad Basada en la Investigación del Cáncer, Guadalajara, Jalisco

Oncologico Potosino, S.C., San Luis Potosí, Not set

Ziekenhuis St. Jansdal, Harderwijk, Gelderland

Jeroen Bosch Hospital, Den Bosch, Noord-Brabant

Erasmus Medisch Centrum, Rotterdam, Zuid-Holland

Amsterdam UMC, locatie VUmc, Amsterdam, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy, Warszawa, Not set

Institutul Oncologic, Bucharest, București

Gral Medical Diagnostic Center, Bucuresti, București

Constanta County Emergency Clinical Hospital Sf.Ap.Andrei, Constanta, Constanța

Cabinet Medical Oncomed, Timișoara, Timiș

Spitalul Universitar de Urgență București, Bucuresti, Not set

Institutul Oncologic, Cluj-Napoca, Not set

Spitalul Județean Sfântul Ioan cel Nou Suceava, Suceava, Not set

GBUZ Republican Clinical Oncological Dispensary, Ufa, Baškortostan, Respublika

Kaluga Regional Clinical Oncology Center, Kaluga, Kalužskaja Oblast

Murmansk Regional Clinical Hospital P.A. Bayandina, Murmansk, Murmanskaya Oblast'

Samara Regional Clinical Oncology Center, Samara, Samarskaya Oblast'

Scientific research institution of oncology named after N.N. Petrov, Saint Petersburg, Sankt-Peterburg

Saint-Petersburg Scientific-Practical Center of Specialized Kinds of Medical Care (oncological) named afte -T, St. Petersburg, Sankt-Peterburg

Arkhangelsk Clinical Oncological Dispensary, Arkhangelsk, Not set

Republican Clinical Oncology Dispensary, Kazan, Not set

First Moscow State Medical University I.M. Sechenov, Moscow, Not set

Hadassah Medical, Moscow, Not set

Tan Tock Seng Hospital, Singapore, Not set

Hospital Fundacion Son Llatzer, Palma de Mallorca, Baleares

Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona]

CHUS - Hospital Clinico Universitario, Santiago de Compostela, Galicia [Galicia]

Hospital Insular de Gran Canaria, Las palmas de gran canaria, Las Palmas

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Clinica Universitaria De Navarra, Pamplona, Navarra

Hospital General Universitario de Alicante, Alicante, Not set

Parc de Salut Mar - Hospital del Mar, Barcelona, Not set

Hospital Universitari Dexeus, Barcelona, Not set

Instituto Catalan de Oncologia - Hospital Duran i Reynals, Barcelona, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Complejo Hospitalario de Jaén, Jaén, Not set

Clinica Universidad de Navarra, Madrid, Not set

Hospital Universitario Ramón y Cajal, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Regional Universitario, Malaga, Not set

Complejo Hospitalario de Navarra, Pamplona, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Hospital Clínico Universitario de Valencia, Valencia, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Changhua Christian Hospital, Changhua County, Changhua

Buddhist Dalin Tzu Chi General Hospital, Dalin Town, Chiayi

Chang Gung Memorial Hospital - Linkou, Guei Shan Township, Taoyuan County

E-Da hospital, Kaohsiung, Not set

Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Not set

Tri-Service General Hospital, Neihu Taipei, Not set

Taipei Medical University Shuang Ho Hospital, New Taipei, Not set

Chung Shan Medical University Hospital, Taichung, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Chi Mei Hospital - Liouying Branch, Tainan City, Not set

National Cheng-Kung Uni. Hosp., Tainan, Not set

National Taiwan University Hospital, Taipei City, Not set

Taipei Veterans General Hospital, Taipei, Not set

Ege Universitesi Hastanesi, Bornova, İzmir

Baskent University Dr. Turgut Noyan Research and Training Center, Adana, Not set

Abdurrahman Yurtaslan Ankara Oncology, education and Research Hospital, Ankara, Not set

Hacettepe University Faculty of Medicine, Ankara, Not set

Memorial Antalya Hastanesi, Antalya, Not set

Dicle Üniversitesi, Diyarbakir, Not set

Trakya University, Edirne, Not set

Istanbul Medeniyet University, Istanbul, Not set

zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi, Izmir, Not set

Izmir Medical Park Hospital, Izmir, Not set

Inonu Universitesi Turgut Ozal Tıp Merkezi, Malatya, Not set

Acıbadem Maslak Hastanesi, Sarıyer, Not set

Municipal Non-profit Enterprise "City Clinical Hospital #4" of Dnipro City Council, "Dnipro State Medical University", Dnipro, Dnipropetrovska Oblast

CNPE "Regional Center of Oncology", Kharkiv, Kharkivska Oblast

Odessa Regional Oncology Center, Odesa, Odeska Oblast

Sumy regional clinical oncological dispensary, Sumy, Sumska Oblast

Communal Noncommercial Enterprise "Podillia Regional Oncology Center Of Vinnytsia Regional Council", Vinnytsia, Vinnytska Oblast

Municipal Enterprise "Volyn Regional Medical Oncology Centre" of the Volyn Regional Council, Lutsk, Volynska Oblast

"Oncolife" LLC, Zaporizhya, Zaporizka Oblast

Regional Municipal Non-profit Enterprise "Bukovinian Clinical Oncology Center", Chernivtsi, Not set

Medical Center "Mriya Med-Service", LLC, Kryvyi Rig, Not set

Municipal non-profit enterprise "Kyiv City Clinical Oncology Center" of executive body of Kyiv City Counci -T, Kyiv, Not set

Municipal non-profit enterprise'Odesa Regional Clinical Hospital'of Odesa Regional Council, Odesa, Not set

City Hospital, Nottingham University Hospitals, Nottingham, Nottinghamshire

Conditions: Non-Small Cell Lung Cancer

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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

NCT04686305

Recruiting

DESTINY-Lung03 will investigate the safety and tolerability of trastuzumab deruxtecan in combination with Immunotherapy Agents with and without chemotherapy in patients with HER2 over-expressing non-small cell lung cancer. The efficacy will be also analyzed as a secondary endpoint.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/16/2025

Locations: Research Site, Duarte, California +79 locations

Research Site, Duarte, California

Research Site, Newport Beach, California

Research Site, Orange, California

Research Site, Santa Rosa, California

Research Site, Westwood, Kansas

Research Site, Baltimore, Maryland

Research Site, Detroit, Michigan

Research Site, Bronx, New York

Research Site, Buffalo, New York

Research Site, New York, New York

Research Site, Houston, Texas

Research Site, Fairfax, Virginia

Research Site, Tacoma, Washington

Research Site, Adelaide, Not set

Research Site, Heidelberg, Not set

Research Site, Nedlands, Not set

Research Site, Edegem, Not set

Research Site, Winnipeg, Manitoba

Research Site, London, Ontario

Research Site, Montreal, Quebec

Research Site, Bordeaux Cedex, Not set

Research Site, Dijon, Not set

Research Site, Pierre-Benite, Not set

Research Site, Saint Herblain, Not set

Research Site, Villejuif Cedex, Not set

Research Site, Kfar-Saba, Not set

Research Site, Tel Hashomer, Not set

Research Site, Milano, Not set

Research Site, Monza, Not set

Research Site, Napoli, Not set

Research Site, Padova, Not set

Research Site, Cheongju-si, Not set

Research Site, Goyang-si, Not set

Research Site, Jinju-si, Not set

Research Site, Seoul, Not set

Research Site, George Town, Not set

Research Site, Kuala Lumpur, Not set

Research Site, Kuching, Not set

Research Site, Selangor, Not set

Research Site, Amsterdam, Not set

Research Site, Bacolod, Not set

Research Site, Cebu City, Not set

Research Site, Davao City, Not set

Research Site, Manila, Not set

Research Site, Quezon City, Not set

Research Site, San Juan, Not set

Research Site, Taguig City, Not set

Research Site, Gdańsk, Not set

Research Site, Kraków, Not set

Research Site, Olsztyn, Not set

Research Site, Tomaszów Mazowiecki, Not set

Research Site, Warszawa, Not set

Research Site, Singapore, Not set

Research Site, Badalona, Not set

Research Site, Madrid, Not set

Research Site, Sevilla, Not set

Research Site, Valencia, Not set

Research Site, Kaohsiung city, Not set

Research Site, Taichung City, Not set

Research Site, Taichung, Not set

Research Site, Tainan, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Bangkok, Not set

Research Site, Hat Yai, Not set

Research Site, Khon Kaen, Not set

Research Site, Muang, Not set

Research Site, Ankara, Not set

Research Site, Bornova-Izmir, Not set

Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer

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A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma

NCT04974398

Active Not Recruiting

This study is a randomized, double-blind, multi-center phase III clinical study to compare the efficacy and safety of penpulimab combined with chemotherapy and placebo combined with chemotherapy in the first-line treatment of recurrent or metastatic nasopharyngeal carcinoma.

Gender:

ALL

Ages:

Between 12 years and 75 years

Trial Updated:

04/10/2025

Locations: City of Hope, Duarte, California +55 locations

City of Hope, Duarte, California

Winship Cancer Institute/Emory University, Atlanta, Georgia

University of Michigan, Ann Arbor, Michigan

Icahn School of Medicine at Mount Sinai, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Chris O'Brien Lifehouse, Camperdown, New South Wales

St Vincent's Public Hospital Sydney, Darlinghurst, New South Wales

Genesis Care North Shore, St Leonards, New South Wales

Sir Charles Gardner, Heidelberg, Victoria

Austin Health, Nedlands, Western Australia

Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, Reg1

Grupo Oncoclínicas, Botafogo, Reg1

Hospital Bruno Born, Lajeado, Reg1

Hospital Nossa Senhora da Conceicao, Porto Alegre, Reg1

Centro de Estudos e Pesquisa de Hematologia, Santo André, Reg1

Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Reg1

Centro de Câncer A. C. Camargo, São Paulo, Reg1

Alberta Health Services (Tom Baker Cancer Centre), Calgary, Alberta

Toronto Sunnybrook Hospital, Toronto, Ontario

The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui

Fujian Cancer Hospital, Fuzhou, Fujian

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian

Dongguan People's Hospital, Dongguan, Guangdong

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong

Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong

Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong

Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong

The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong

The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong

Guangzhou Panyu Central Hospital, Guangzhou, Guangdong

Jiangmen Central Hospital, Jiangmen, Guangdong

Cancer Hospital of Shantou University Medical College, Shantou, Guangdong

Shenzhen People's Hospital, Shenzhen, Guangdong

Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong

The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong

Affiliated Hospital of Guilin Medical University, Guilin, Guangxi

The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi

Guangxi Medical University Cancer Hospital, Nanning, Guangxi

The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi

Guizhou Cancer Hospital, Guiyang, Guizhou

The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan

Hainan General Hospital, Haikou, Hainan

Hubei Cancer Hospital, Wuhan, Hubei

The Second Xiangya Hospital of Central South University, Changsha, Hunan

Hunan Cancer Hospital, Changsha, Hunan

The First Affiliated Hospital of University of South China, Hengyang, Hunan

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Jiangxi Cancer Hospital, Nanchang, Jiangxi

Fudan University Shanghai Cancer Center, Shanghai, Shanghai

Sichuan Cancer Hospital, Chengdu, Sichuan

The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan

Yunnan Cancer Hospital, Kunming, Yunnan

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang

Conditions: Nasopharyngeal Carcinoma

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Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

NCT04185883

Recruiting

To evaluate the safety and tolerability of sotorasib administered in investigational regimens in adult participants with KRAS p.G12C mutant advanced solid tumors.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

03/26/2025

Locations: Arizona Oncology Associates Professional Corporation, Tucson, Arizona +89 locations

Arizona Oncology Associates Professional Corporation, Tucson, Arizona

City of Hope National Medical Center, Duarte, California

University of California San Diego Moores Cancer Center, La Jolla, California

Loma Linda University Cancer Center, Loma Linda, California

University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California

University of California Davis Medical Center, Sacramento, California

University of California San Francisco Mission Bay Campus, San Francisco, California

University of California Los Angeles, Santa Monica, California

Rocky Mountain Cancer Centers Denver Midtown, Denver, Colorado

Sarah Cannon Research Institute, Denver, Colorado

Yale New Haven Hospital, New Haven, Connecticut

Norwalk Hospital, Norwalk, Connecticut

Memorial Cancer Institute, Pembroke Pines, Florida

Moffitt Cancer Center, Tampa, Florida

Emory University, Atlanta, Georgia

Northwestern University, Chicago, Illinois

University of Chicago, Chicago, Illinois

Indiana University, Indianapolis, Indiana

University of Iowa Hospitals and Clinics, Iowa City, Iowa

Johns Hopkins University, Baltimore, Maryland

University of Michigan, Ann Arbor, Michigan

Henry Ford Cancer Detroit (Brigitte Harris Cancer Pavilion), Detroit, Michigan

Washington University, Saint Louis, Missouri

Montefiore Medical Center, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Columbia University Irving Medical Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Levine Cancer Institute, Charlotte, North Carolina

Duke University, Durham, North Carolina

University of Cincinnati Medical Center, Cincinnati, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Providence Portland Medical Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Thomas Jefferson University, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

University of Pennsylvania, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Gibbs Cancer Center and Research Institute - Spartanburg, Spartanburg, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

United States Oncology Regulatory Affairs Corporate Office, Nashville, Tennessee

Vanderbilt University Medical Center, Nashville, Tennessee

Texas Oncology Central-South, Austin, Texas

Mary Crowley Cancer Research, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Oncology Consultants, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

US Oncology Research Investigational Products Center, The Woodlands, Texas

Texas Oncology Northeast Texas, Tyler, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Virginia Cancer Specialists, PC, Fairfax, Virginia

Fred Hutchinson Cancer Center, Seattle, Washington

Northwest Medical Specialties, PLLC, Tacoma, Washington

Northwest Cancer Specialists - Vancouver, Vancouver, Washington

Nepean Cancer Centre, Kingswood, New South Wales

GenesisCare -North Shore Oncology, St Leonards, New South Wales

Icon Cancer Care South Brisbane, South Brisbane, Queensland

The Queen Elizabeth Hospital, Woodville South, South Australia

St John of God Healthcare, Subiaco, Western Australia

Medizinische Universitaet Graz, Graz, Not set

Landeskrankenhaus Salzburg, Salzburg, Not set

Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Bruxelles, Not set

Universitair Ziekenhuis Antwerpen, Edegem, Not set

CHU de Quebec Hopital de l Enfant Jesus, Quebec, Not set

Charite Universitaetsmedizin Berlin, Campus Virchow, Berlin, Not set

Universitaetsklinikum Dresden, Dresden, Not set

Universitaetsklinikum Essen, Essen, Not set

Universitatsklinikum Koln, Koeln, Not set

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Not set

Azienda Ospedaliero Universitaria Pisana, Pisa, Not set

Centro Ricerche Cliniche Di Verona Societa responsabilita limitata, Verona, Not set

Aichi Cancer Center, Nagoya-shi, Aichi

National Cancer Center Hospital East, Kashiwa-shi, Chiba

The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo

Seoul National University Hospital, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Hospital Universitari Vall d Hebron, Barcelona, Cataluña

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña

Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals, Hospitalet de Llobregat, Cataluña

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Hospital Universitario Ramon y Cajal, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation, Taoyuan, Not set

Sarah Cannon Research Institute UK, London, Not set

Conditions: Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation

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A Study of GSK5764227 in Participants With Advanced Solid Tumors

NCT06551142

Recruiting

The goal of this study is to assess the safety, tolerability, clinical activity and pharmacokinetics of GSK5764227. The study will also see how the levels of GSK5764227 will change over time at different dose amounts when administered alone and in combination with other medicines like carboplatin, cisplatin, atezolizumab, pembrolizumab, durvalumab, bevacizumab, cetuximab.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/13/2025

Locations: GSK Investigational Site, Denver, Colorado +13 locations

Conditions: Neoplasms

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Prostate Cancer Biomarker Enrichment and Treatment Selection

NCT03385655

Active Not Recruiting

The purpose of the pre-study screening is to test for DNA abnormalities or biomarkers.

Gender:

MALE

Ages:

18 years and above

Trial Updated:

03/12/2025

Locations: Cross Cancer Institute, Edmonton, Alberta +10 locations

Conditions: Prostate Cancer

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Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

NCT04956640

Recruiting

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific genetic mutation (KRAS G12C). Patients must have already received or were not able to tolerate the standard of care, except for specific groups who have not had cancer treatment. The study will last up to approximately 4 years.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/05/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +48 locations

University of Alabama at Birmingham, Birmingham, Alabama

USC Norris Cancer Hospital, Los Angeles, California

Chao Family Comprehensive Cancer Ctr., Orange, California

Yale-New Haven Hospital, New Haven, Connecticut

AdventHealth Orlando, Orlando, Florida

Florida Cancer Specialists, Sarasota, Florida

Indiana Univ Melvin & Bren Simon Cancer Center, Indianapolis, Indiana

Community Health Network, Indianapolis, Indiana

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana

Massachusetts General Hospital, Boston, Massachusetts

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

NYU Langone Health- Long Island, Mineola, New York

NYU Langone, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina

Novant Health Cancer Institute - Forsyth, Winston-Salem, North Carolina

Fox Chase Cancer Center, Philadelphia, Pennsylvania

UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania

Sarah Cannon Cancer Center, Nashville, Tennessee

Vanderbilt Univeristy School of Medicine, Nashville, Tennessee

South Texas Accelerated Research Therapeutics (START), San Antonio, Texas

START Mountain Region, West Valley City, Utah

Inova Health System IRB, Fairfax, Virginia

USO-Virginia Cancer Specialists, PC, Fairfax, Virginia

University of Wisconsin-Madison Hospital and Health Clinic, Madison, Wisconsin

Royal North Shore Hospital, St Leonards, New South Wales

St Vincent's Hospital Sydney, Sydney, New South Wales

Cancer Research SA, Adelaide, South Australia

Peninsula and Southeast Oncology, Frankston, Victoria

Linear Clinical Research, Nedlands, Western Australia

Cross Cancer Institute, Edmonton, Alberta

Princess Margaret Hospital (Ontario), Toronto, Ontario

Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Aquitaine

Centre Leon Berard, Lyon, Rhône-Alpes

Institut du Cancer de Montpellier - Val d'aurelle, Montpellier Cedex 5, Not set

Institut Claudius Regaud - IUCT Oncopole, Toulouse cedex, Not set

Gustave Roussy, Villejuif Cedex, Not set

Aichi Cancer Center Hospital, Nagoya, Aichi

National Cancer Center Hospital East, Kashiwa, Chiba

Hokkaido University Hospital, Sapporo, Hokkaido

Kanazawa University Hospital, Kanazawa-shi, Ishikawa

National Cancer Center Hospital, Chuo-ku, Tokyo

Wakayama Medical University Hospital, Wakayama, Not set

National Cancer Center, Goyang-si, Gyeonggi-do

The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do

Chonnam National University Hwasun Hospital, Hwasun-gun, Jeonranamdo

Seoul National University Hospital, Seoul, Korea

Asan Medical Center, Seoul, Korea

Conditions: Carcinoma, Non-Small-Cell Lung, Endometrial Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Biliary Tract Neoplasms, Colorectal Neoplasms

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Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer

NCT04460352

Recruiting

NEEDS is a pragmatic open-label, randomised, controlled, phase III, multicenter trial with non-inferiority design with regard to the first co-primary endpoint overall survival and superiority for the experimental intervention definitive chemoradiotherapy. A second co-primary endpoint is global health related quality of life (HRQOL) one year after randomisation. A third co-primary endpoint is eating restictions one year after randomisation. The aim is to compare outcomes after neoadjuvant chemor... Read More

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

03/04/2025

Locations: McGill University Health Centre, Montréal, Quebec +11 locations

Conditions: Esophageal Squamous Cell Carcinoma

Learn More ›