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Carboplatin Treatment Options in Canada
A collection of 336 research studies where Carboplatin is the interventional treatment. These studies are located in the Canada . Carboplatin is used for conditions such as Non-Small Cell Lung Cancer, Ovarian Cancer and Lung Cancer.
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A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors
Completed
In this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies. Part 1 considered escalating doublet (NKTR 214 + nivolumab) doses to determine the RP2D. Part 2 considered dose expansion cohorts for the doublet (NKTR 214 + nivolumab ± chemotherapy). Part 3 was schedule-finding for a triplet therapy (NKTR 214 + nivolumab + ipilimumab). Part 4 dose expansion for the triplet (NKTR 214 + nivolumab + ipilimumab) was planned to further asses... Read More
In this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies. Part 1 considered escalating doublet (NKTR 214 + nivolumab) doses to determine the RP2D. Part 2 considered dose expansion cohorts for the doublet (NKTR 214 + nivolumab ± chemotherapy). Part 3 was schedule-finding for a triplet therapy (NKTR 214 + nivolumab + ipilimumab). Part 4 dose expansion for the triplet (NKTR 214 + nivolumab + ipilimumab) was planned to further assess the efficacy of the RP2D triplet combination at dosing schedules from Part 3. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/09/2023
Locations: UCSD, Moores Cancer Center, La Jolla, California +57 locations
UCSD, Moores Cancer Center, La Jolla, California
UCLA, Los Angeles, California
Stanford Cancer Institute, Stanford, California
University of Colorado, Denver, Denver, Colorado
Yale School of Medicine, New Haven, Connecticut
University of Florida, Gainesville, Florida
Orlando Health Inc., Orlando, Florida
Emory University Hospital, Atlanta, Georgia
Loyola University Medical Center, Chicago, Maywood, Illinois
Indiana University Health Melvin & Bren Simon Cancer Center, Indianapolis, Indiana
University of Kansas Cancer Center, Kansas City, Kansas
Dana-Farber Cancer Institute, Boston, Massachusetts
Henry Ford Hospital, Detroit, Michigan
Washington University School of Medicine in St. Louis, Saint Louis, Missouri
Roswell Park Cancer Institute, Buffalo, New York
New York University Langone Medical Center - NYU Cancer Institute, New York, New York
Memorial Sloan-Kettering Cancer Center, New York, New York
Providence Portland Medical Center, Portland, Oregon
The University of Texas MD Anderson Cancer Center, Houston, Texas
Inova Fairfax Hospital, Fairfax, Virginia
Virginia Cancer Specialists, PC, Fairfax, Virginia
Seattle Cancer Care Alliance, Seattle, Washington
Antwerp University Hospital, Edegem, Not set
Vzw Az Groeninge, Kortrijk, Not set
UZ Leuven, Leuven, Not set
CHU de Liège, Liège, Not set
GZA Ziekenhuizen Campus Sint-Augustinus, Wilrijk, Not set
BC Cancer Agency Vancouver Centre, Vancouver, British Columbia
Sunnybrook Health Sciences Centre, Toronto, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Jewish General Hospital, Montréal, Quebec
L'Institut Paoli - Calmettes, Marseille, Brouches-duRhone
Institut de Cancerologie de l'Ouest, Saint-Herblain, Loire-Atlantique
Centre Léon Bérard, Lyon, Not set
Assistance Publique Hopitaux de Marseille - Hopital Nord, Marseille Cedex 20, Not set
Gustave Roussy, Villejuif, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set
Istituto Europeo di Oncologia, Milano, Not set
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Napoli, Not set
Azienda Ospedaliera San Camillo-Forlanini, Roma, Not set
Azienda Ospedaliera Universitaria Senese, Siena, Not set
Institute for Cancer Research and Treatment (IRCC), Turin, Not set
Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im. Ks. B. Markiewicza, Brzozów, Not set
Szpitale Pomorskie Sp. z o.o., Gdynia, Not set
Mazowieckie Centrum Leczenia Chorób Płuc i Gruźlicy, Otwock, Not set
Wielkopolskie Centrum Pulmonologii i Torakochirurgii, Poznań, Not set
Med-Polonia Sp. z o.o., Poznań, Not set
Instytut Medyczny Santa Familia Sp. z o. o. w Łodzi, Łódź, Not set
Hospital Quirón Barcelona, Barcelona, Not set
Hospital Clínic de Barcelona, Barcelona, Not set
Hospital Universitario Ramón y Cajal, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Not set
Clínica Universidad de Navarra, Pamplona, Not set
Campus Hospital Universitario Virgen del Rocío - Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Not set
The Royal Marsden NHS Trust, London, Not set
Mount Vernon Cancer Centre, Northwood, Not set
The Christie NHS Foundation Trust, Withington, Not set
Conditions: Melanoma, Renal Cell Carcinoma, Non Small Cell Lung Cancer, Urothelial Carcinoma, Triple Negative Breast Cancer, HR+/HER2- Breast Cancer, Gastric Cancer
Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer
Completed
The purpose of part 1 of this study is to determine the objective response rate (ORR) in stage IV NSCLC subjects treated with nivolumab in combination with ipilimumab as first line therapy.
The purpose of part 2 of this study is to determine the safety and tolerability of nivolumab and ipilimumab combined with a short course of chemotherapy in first line stage IV NSCLC.
The purpose of part 1 of this study is to determine the objective response rate (ORR) in stage IV NSCLC subjects treated with nivolumab in combination with ipilimumab as first line therapy.
The purpose of part 2 of this study is to determine the safety and tolerability of nivolumab and ipilimumab combined with a short course of chemotherapy in first line stage IV NSCLC. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2023
Locations: Sharp Memorial Hospital, San Diego, California +31 locations
Sharp Memorial Hospital, San Diego, California
Cancer Center Of Central Connecticut, Plainville, Connecticut
Cleveland Clinic Florida, Weston, Florida
Winship Cancer Institute., Atlanta, Georgia
Summit Cancer Care, Savannah, Georgia
Cancer Center Of Kansas, Wichita, Kansas
University Of Louisville Medical Center, Inc., Dba, Louisville, Kentucky
Johns Hopkins Cancer Center, Baltimore, Maryland
Local Institution - 0029, Boston, Massachusetts
Local Institution - 0030, Boston, Massachusetts
Massachusetts General Hospital, Boston, Massachusetts
Henry Ford Health System, Detroit, Michigan
Local Institution - 0015, Lincoln, Nebraska
Hackensack University Medical Center, Hackensack, New Jersey
Local Institution - 0036, Albuquerque, New Mexico
Lovelace Cancer Care, Albuquerque, New Mexico
New Mexico Cancer Care Alliance, Albuquerque, New Mexico
New Mexico Cancer Care Center, Albuquerque, New Mexico
The Cancer Center at Presbyterian, Albuquerque, New Mexico
Local Institution - 0010, Mineola, New York
Memorial Sloan Kettering Nassau, New York, New York
Duke University, Durham, North Carolina
Novant Health Oncology Specialists, Winston-Salem, North Carolina
The Ohio State University, Columbus, Ohio
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Local Institution - 0006, Pittsburgh, Pennsylvania
Charleston Hematology Oncology Associates, Pa, Charleston, South Carolina
Tennessee Oncology, PLLC - SCRI - PPDS, Nashville, Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee
Local Institution - 0022, Kingston, Ontario
Local Institution - 0023, Sault Ste Marie, Ontario
Csss De St-Jerome, St. Jerome, Quebec
Conditions: Non-Small-Cell Lung Cancer
An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)
Completed
The purpose of this study is to show that Nivolumab will improve progression free survival in subjects with strongly Stage IV or Recurrent PD-L1+ non-small cell lung cancer when compared to chemotherapy
The purpose of this study is to show that Nivolumab will improve progression free survival in subjects with strongly Stage IV or Recurrent PD-L1+ non-small cell lung cancer when compared to chemotherapy Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2023
Locations: Southern Cancer Center, Inc., Mobile, Alabama +140 locations
Southern Cancer Center, Inc., Mobile, Alabama
Banner MD Anderson Cancer Center, Gilbert, Arizona
Local Institution - 0034, Tucson, Arizona
Local Institution - 0016, Stanford, California
University Of Colorado Hosp, Aurora, Colorado
Local Institution - 0020, New Haven, Connecticut
Local Institution - 0030, Miami, Florida
Local Institution - 0033, Ocala, Florida
H. Lee Moffitt Cancer Center, Tampa, Florida
Local Institution - 0010, Atlanta, Georgia
Northwest Georgia Oncology Center, P.C., Marietta, Georgia
Local Institution - 0037, Chicago, Illinois
Local Institution - 0014, Lexington, Kentucky
Crescent City Research Consortium, LLC, Marrero, Louisiana
Local Institution - 0024, Baltimore, Maryland
Local Institution - 0036, Boston, Massachusetts
Local Institution - 0070, Boston, Massachusetts
Roswell Park Cancer Institute, Buffalo, New York
Local Institution - 0009, New York, New York
Local Institution - 0005, New York, New York
University Of North Carolina At Chapel Hill, Chapel Hill, North Carolina
Local Institution - 0003, Durham, North Carolina
Local Institution - 0012, Cleveland, Ohio
Local Institution - 0027, Columbus, Ohio
Oregon Health & Science University, Portland, Oregon
Local Institution - 0007, Allentown, Pennsylvania
Local Institution - 0054, Philadelphia, Pennsylvania
Local Institution - 0002, Philadelphia, Pennsylvania
Local Institution - 0018, Pittsburgh, Pennsylvania
Local Institution - 0011, Charleston, South Carolina
Local Institution - 0038, Greenville, South Carolina
Local Institution - 0008, Nashville, Tennessee
Local Institution - 0006, Dallas, Texas
Local Institution - 0023, Houston, Texas
Cancer Centers of South Texas, San Antonio, Texas
Local Institution - 0029, Yakima, Washington
Local Institution - 0051, Berazategui, Buenos Aires
Local Institution - 0049, Capital Federal, Buenos Aires
Local Institution - 0052, Ciudad Autonoma De Buenos Aire, Buenos Aires
Local Institution - 0048, Cordoba, Not set
Local Institution - 0050, Cordoba, Not set
Local Institution - 0090, Camperdown, New South Wales
Local Institution - 0091, Brisbane, Queensland
Local Institution - 0071, Elizabeth Vale, South Australia
Local Institution - 0072, Fitzroy, Victoria
Local Institution - 0104, Heidelberg, Victoria
Local Institution - 0088, Wels, Not set
Local Institution - 0087, Wien, Not set
Local Institution - 0044, Brussels, Not set
Local Institution - 0055, Edegem, Not set
Local Institution - 0056, Gent, Not set
Local Institution - 0062, Leuven, Not set
Local Institution - 0134, Ijui, Rio Grande Do Sul
Local Institution - 0133, Porto Alegre, Rio Grande Do Sul
Local Institution - 0135, Barretos, Sao Paulo
Local Institution - 0086, Calgary, Alberta
Local Institution - 0115, Hamilton, Ontario
Local Institution - 0113, Toronto, Ontario
Local Institution - 0110, Montreal, Quebec
Local Institution - 0109, Rimouski, Quebec
Local Institution - 0059, Olomouc, Not set
Local Institution - 0061, Ostrava - Poruba, Not set
Local Institution - 0058, Praha 8, Not set
Local Institution - 0060, Usti nad Labem, Not set
Local Institution - 0120, Helsinki, Not set
Local Institution - 0119, Tampere, Not set
Local Institution - 0118, Vaasa, Not set
Local Institution - 0123, Caen, Not set
Local Institution - 0105, Lille, Not set
Local Institution - 0102, Marseille Cedex 20, Not set
Local Institution - 0167, Pontoise Cedex, Not set
Local Institution - 0100, Rennes Cedex 9, Not set
Local Institution - 0140, Strasbourg, Not set
Local Institution - 0074, Bamberg, Not set
Local Institution - 0065, Grosshansdorf, Not set
Local Institution - 0064, Heidelberg, Not set
Local Institution - 0063, Koeln, Not set
Local Institution - 0066, Stuttgart, Not set
Local Institution - 0092, Wiesbaden, Not set
Local Institution - 0073, Heraklion, Creta
Local Institution - 0075, Athens, Not set
Local Institution - 0126, Budapest, Not set
Local Institution - 0116, Debrecen, Not set
Local Institution - 0094, Matrahaza, Not set
Local Institution - 0084, Avellino, Not set
Local Institution - 0079, Livorno, Not set
Local Institution - 0143, Milano, Not set
Local Institution - 0142, Napoli, Not set
Local Institution - 0083, Perugia, Not set
Local Institution - 0082, Terni, Not set
Local Institution - 0161, Nagoya-shi, Aichi
Local Institution - 0146, Nagoya, Aichi
Local Institution - 0148, Matsuyama-shi, Ehime
Local Institution - 0153, Kobe City, Hyogo
Local Institution - 0144, Natori-shi, Miyagi
Local Institution - 0151, Niigata-shi, Niigata
Local Institution - 0166, Habikino-shi, Osaka
Local Institution - 0147, Miyakojima-ku, Osaka
Local Institution - 0145, Osaka-sayama, Osaka
Local Institution - 0152, Sakai, Osaka
Local Institution - 0150, Kitaadachi-gun, Saitama
Local Institution - 0149, Sunto-gun, Shizuoka
Local Institution - 0154, Chuo-ku, Tokyo
Local Institution - 0159, Akashi, Hyogo, Not set
Local Institution - 0162, Ota, Gunma, Not set
Local Institution - 0165, Sapporo, Hokkaido, Not set
Local Institution - 0160, Tokyo, Not set
Local Institution - 0158, Wakayama, Not set
Local Institution - 0155, Gangnam-gu, Not set
Local Institution - 0164, Seoul, Not set
Local Institution - 0163, Seoul, Not set
Local Institution - 0117, Mexico, Distrito Federal
Local Institution - 0122, Guadalajara, Jalisco
Local Institution - 0124, Merida, Yucatan
Local Institution - 0045, Amsterdam, Not set
Local Institution - 0057, Groningen, Not set
Local Institution - 0046, Rotterdam, Not set
Local Institution - 0114, Bydgoszcz, Not set
Local Institution - 0131, Krakow, Not set
Local Institution - 0139, Lodz, Not set
Local Institution - 0089, Warszawa, Not set
Local Institution - 0093, Wodzislaw Slaski, Not set
Local Institution - 0068, Cluj Napoca, Not set
Local Institution - 0067, Cluj-napoca, Not set
Local Institution - 0069, Ploiesti, Not set
Local Institution - 0040, Barcelona, Not set
Local Institution - 0041, Las Palmas De Gran Canaria, Not set
Local Institution - 0047, Madrid, Not set
Local Institution - 0042, Malaga, Not set
Local Institution - 0039, Sevilla, Not set
Local Institution - 0043, Valencia, Not set
Local Institution - 0127, Stockholm, Not set
Local Institution - 0125, Uppsala, Not set
Local Institution - 0076, Chur, Not set
Local Institution - 0077, Lausanne, Not set
Local Institution - 0078, Zuerich, Not set
Local Institution - 0157, Taipei, Not set
Local Institution - 0130, Kayseri, Not set
Local Institution - 0098, London, Greater London
Local Institution - 0097, Manchester, Greater Manchester
Local Institution - 0053, Leeds, Yorkshire
Conditions: Stage IV or Recurrent Non-Small Cell Lung Cancer
A Study of Efficacy and Safety of LAG525 in Combination With Spartalizumab, or With Spartalizumab and Carboplatin, or With Carboplatin, in Patients With Advanced Triple-negative Breast Cancer
Completed
The main purpose of this study was to assess the antitumor activity of three combinations: i) LAG525 + spartalizumab; ii) LAG525 + spartalizumab + carboplatin, and iii) LAG525 + carboplatin in participants with advanced triple-negative breast cancer (TNBC) in first or second line therapy.
The main purpose of this study was to assess the antitumor activity of three combinations: i) LAG525 + spartalizumab; ii) LAG525 + spartalizumab + carboplatin, and iii) LAG525 + carboplatin in participants with advanced triple-negative breast cancer (TNBC) in first or second line therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2023
Locations: Ironwood Cancer and Research Centers, Chandler, Arizona +32 locations
Ironwood Cancer and Research Centers, Chandler, Arizona
Highlands Oncology Group, Fayetteville, Arkansas
Novartis Investigative Site, Caba, Buenos Aires
Novartis Investigative Site, Wooloongabba, Queensland
Novartis Investigative Site, Melbourne, Victoria
Novartis Investigative Site, Nedlands, Western Australia
Novartis Investigative Site, Liege, Not set
Novartis Investigative Site, Montreal, Quebec
Novartis Investigative Site, Quebec, Not set
Novartis Investigative Site, Paris, Not set
Novartis Investigative Site, Luebeck, Schleswig-holstein
Novartis Investigative Site, Erlangen, Not set
Novartis Investigative Site, Tübingen, Not set
Novartis Investigative Site, Budapest, Not set
Novartis Investigative Site, Szeged, Not set
Novartis Investigative Site, Tel Aviv, Not set
Novartis Investigative Site, Napoli, Not set
Novartis Investigative Site, Nagoya-city, Aichi
Novartis Investigative Site, Nagoya, Aichi
Novartis Investigative Site, Yokohama-city, Kanagawa
Novartis Investigative Site, Minato ku, Tokyo
Novartis Investigative Site, Seoul, Korea
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Ashrafieh, Not set
Novartis Investigative Site, El Metn, Not set
Novartis Investigative Site, Saida, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Sevilla, Andalucia
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Songkla, Not set
Conditions: Triple-negative Breast Cancer
Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma
Completed
This phase II trial studies how well combination chemotherapy works in treating younger patients with newly diagnosed, non-metastatic desmoplastic medulloblastoma. Drugs used in chemotherapy, such as vincristine sulfate, cyclophosphamide, methotrexate, etoposide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
This phase II trial studies how well combination chemotherapy works in treating younger patients with newly diagnosed, non-metastatic desmoplastic medulloblastoma. Drugs used in chemotherapy, such as vincristine sulfate, cyclophosphamide, methotrexate, etoposide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Read Less
Gender:
ALL
Ages:
47 months and below
Trial Updated:
01/04/2023
Locations: Children's Hospital of Alabama, Birmingham, Alabama +172 locations
Children's Hospital of Alabama, Birmingham, Alabama
Phoenix Childrens Hospital, Phoenix, Arizona
Banner University Medical Center - Tucson, Tucson, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Kaiser Permanente Downey Medical Center, Downey, California
City of Hope Comprehensive Cancer Center, Duarte, California
Loma Linda University Medical Center, Loma Linda, California
Miller Children's and Women's Hospital Long Beach, Long Beach, California
Children's Hospital Los Angeles, Los Angeles, California
Valley Children's Hospital, Madera, California
UCSF Benioff Children's Hospital Oakland, Oakland, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Sutter Medical Center Sacramento, Sacramento, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
Rady Children's Hospital - San Diego, San Diego, California
UCSF Medical Center-Parnassus, San Francisco, California
UCSF Medical Center-Mission Bay, San Francisco, California
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California
Children's Hospital Colorado, Aurora, Colorado
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado
Connecticut Children's Medical Center, Hartford, Connecticut
Yale University, New Haven, Connecticut
Alfred I duPont Hospital for Children, Wilmington, Delaware
MedStar Georgetown University Hospital, Washington, District of Columbia
Children's National Medical Center, Washington, District of Columbia
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Nicklaus Children's Hospital, Miami, Florida
AdventHealth Orlando, Orlando, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Orlando Health Cancer Institute, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Nemours Children's Clinic - Pensacola, Pensacola, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida
Saint Mary's Hospital, West Palm Beach, Florida
Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia
Augusta University Medical Center, Augusta, Georgia
Memorial Health University Medical Center, Savannah, Georgia
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Lurie Children's Hospital-Chicago, Chicago, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Loyola University Medical Center, Maywood, Illinois
Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois
Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Riley Hospital for Children, Indianapolis, Indiana
Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana
Blank Children's Hospital, Des Moines, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Norton Children's Hospital, Louisville, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Ochsner Medical Center Jefferson, New Orleans, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Maine Children's Cancer Program, Scarborough, Maine
Sinai Hospital of Baltimore, Baltimore, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Walter Reed National Military Medical Center, Bethesda, Maryland
UMass Memorial Medical Center - University Campus, Worcester, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan
Ascension Saint John Hospital, Detroit, Michigan
Michigan State University Clinical Center, East Lansing, Michigan
Hurley Medical Center, Flint, Michigan
Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan
Bronson Methodist Hospital, Kalamazoo, Michigan
Beaumont Children's Hospital-Royal Oak, Royal Oak, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Columbia Regional, Columbia, Missouri
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Sunrise Hospital and Medical Center, Las Vegas, Nevada
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Hackensack University Medical Center, Hackensack, New Jersey
Morristown Medical Center, Morristown, New Jersey
Saint Peter's University Hospital, New Brunswick, New Jersey
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Newark Beth Israel Medical Center, Newark, New Jersey
Saint Joseph's Regional Medical Center, Paterson, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Albany Medical Center, Albany, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
Roswell Park Cancer Institute, Buffalo, New York
NYU Winthrop Hospital, Mineola, New York
The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Mount Sinai Hospital, New York, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
State University of New York Upstate Medical University, Syracuse, New York
New York Medical College, Valhalla, New York
Mission Hospital, Asheville, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Broadway Medical Center, Fargo, North Dakota
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Rainbow Babies and Childrens Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Nationwide Children's Hospital, Columbus, Ohio
Dayton Children's Hospital, Dayton, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Legacy Emanuel Children's Hospital, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Penn State Children's Hospital, Hershey, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
T C Thompson Children's Hospital, Chattanooga, Tennessee
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Dell Children's Medical Center of Central Texas, Austin, Texas
Driscoll Children's Hospital, Corpus Christi, Texas
Medical City Dallas Hospital, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
El Paso Children's Hospital, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Children's Hospital of San Antonio, San Antonio, Texas
Methodist Children's Hospital of South Texas, San Antonio, Texas
University of Texas Health Science Center at San Antonio, San Antonio, Texas
Scott and White Memorial Hospital, Temple, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Vermont and State Agricultural College, Burlington, Vermont
Inova Fairfax Hospital, Falls Church, Virginia
Children's Hospital of The King's Daughters, Norfolk, Virginia
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia
Carilion Children's, Roanoke, Virginia
Seattle Children's Hospital, Seattle, Washington
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
West Virginia University Healthcare, Morgantown, West Virginia
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
Children's Hospital of Wisconsin, Milwaukee, Wisconsin
John Hunter Children's Hospital, Hunter Regional Mail Centre, New South Wales
Women's and Children's Hospital-Adelaide, North Adelaide, South Australia
Princess Margaret Hospital for Children, Perth, Western Australia
Alberta Children's Hospital, Calgary, Alberta
British Columbia Children's Hospital, Vancouver, British Columbia
CancerCare Manitoba, Winnipeg, Manitoba
Janeway Child Health Centre, Saint John's, Newfoundland and Labrador
IWK Health Centre, Halifax, Nova Scotia
McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario
Hospital for Sick Children, Toronto, Ontario
The Montreal Children's Hospital of the MUHC, Montreal, Quebec
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec
Centre Hospitalier Universitaire de Quebec, Quebec, Not set
San Jorge Children's Hospital, San Juan, Not set
University Pediatric Hospital, San Juan, Not set
Conditions: Desmoplastic/Nodular Medulloblastoma, Medulloblastoma, Medulloblastoma With Extensive Nodularity, Nevoid Basal Cell Carcinoma Syndrome
Efficacy and Safety of Farletuzumab (MORAb-003) in Combination With Carboplatin and Taxane in Participants With Platinum-sensitive Ovarian Cancer in First Relapse
Terminated
This research is being done to find out if Carboplatin and Taxane works better alone or when given with an experimental drug called MORAb-003(farletuzumab) in subjects with first platinum sensitive relapsed ovarian cancer.
This research is being done to find out if Carboplatin and Taxane works better alone or when given with an experimental drug called MORAb-003(farletuzumab) in subjects with first platinum sensitive relapsed ovarian cancer. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/05/2022
Locations: University Of Alabama At Birmingham, Birmingham, Alabama +374 locations
University Of Alabama At Birmingham, Birmingham, Alabama
Oncology Specialties, PC, Huntsville, Alabama
Arizona Hematology & Oncology Associates, Phoenix, Arizona
St. Joseph's Hospital, Barrow Neurology Clinics, Phoenix, Arizona
Arizona Oncology Associates, Tucson, Arizona
Arizona Cancer Center, Tucson, Arizona
Providence St. Joseph Medical Center, Burbank, California
California Cancer Care, Inc., Greenbrae, California
University of California San Diego, La Jolla, California
University of California Los Angeles Medical Center, Los Angeles, California
Gynecologic Oncology Associates, Newport Beach, California
University of California Davis Cancer Center, Sacramento, California
Stanford University, Stanford, California
University of Colorado, Aurora, Colorado
Catholic Health Initiatives, Colorado Springs, Colorado
Denver Health and Hospital Authority, Denver, Colorado
Hematology Oncology P.C., Stamford, Connecticut
Washington Hospital Center, Washington, District of Columbia
Palm Beach Institute of Hematology and Oncology, Boynton Beach, Florida
University Cancer Institute, Boynton Beach, Florida
Gainsville Hematology Oncology Associates, Gainesville, Florida
Baptist Cancer Institute, Jacksonville, Florida
Jupiter Medical center Physician's Group, Jupiter, Florida
Hematology/Oncology Associates, Lake Worth, Florida
Lakeland Regional Cancer Center, Lakeland, Florida
Florida Hospital, Orlando, Florida
Gulfcoast Oncology, Saint Petersburg, Florida
Sarasota Memorial Healthcare System, Sarasota, Florida
Oncology-Hematology Associates of W. Broward P.A., Tamarac, Florida
Palm Beach Cancer Institute, West Palm Beach, Florida
Medical College of Georgia, Augusta, Georgia
Memorial Health University Medical Center, Savannah, Georgia
Kaiser Permanente - Moanalua Medical Center, Honolulu, Hawaii
Kapi'olani Medical Center for Women and Children, Honolulu, Hawaii
Medical & Surgical Specialists, LLC, Galesburg, Illinois
Ingalls Memorial Hospital, Harvey, Illinois
Loyola University Chicago, Maywood, Illinois
Midwest Cancer Research Group, Skokie, Illinois
Central DuPage Hospital, Winfield, Illinois
St. Francis Hospital & Health Centers, Indianapolis, Indiana
St. Vincent Gynecologic Oncology, Indianapolis, Indiana
Central Baptist Hospital, Lexington, Kentucky
University of Louisville, Louisville, Kentucky
Norton Healthcare, Louisville, Kentucky
Hematology & Oncology Specialists, Metairie, Louisiana
Mercy Medical Center, Baltimore, Maryland
Greater Baltimore Medical Center, Baltimore, Maryland
John Hopkins University, Baltimore, Maryland
Weinberg Cancer Institute at Franklin Square, Baltimore, Maryland
Center for Cancer and Blood Disorders, Bethesda, Maryland
Frederick Memorial Hospital, Frederick, Maryland
Barbara Ann Kamanos Cancer Center, Detroit, Michigan
Henry Ford Health System, Detroit, Michigan
Saint Mary's Health Care, Grand Rapids, Michigan
Sparrow Regional Cancer Center, Lansing, Michigan
Park Nicollet Institute, Saint Louis Park, Minnesota
Saint Francis Memorial Health Center, Grand Island, Nebraska
Good Samaritan Hospital Cancer Center, Kearney, Nebraska
The Center for Cancer and Hematologic Disease, Camden, New Jersey
Hematology-Oncolgy Associates of NNJ-PA, Denville, New Jersey
John Theurer Cancer Center at Hackensack University MC, Hackensack, New Jersey
Morristown Memorial Hospital, Morristown, New Jersey
Cooper Cancer Institute, Voorhees, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Roswell Park Cancer Institute, Buffalo, New York
Arena Oncology Associates, Lake Success, New York
Columbia University Medical Center, New York, New York
SUNY Upstate Medical University, Syracuse, New York
Carolinas Medical Center, Charlotte, North Carolina
Presbyterian Hospital, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
Piedmont Hematology & Oncology, Winston-Salem, North Carolina
Catholic Health Initiatives, Cincinnati, Ohio
University Hospitals of Cleveland, Cleveland, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Miami Valley Hospital, Dayton, Ohio
Kettering Medical Center, Kettering, Ohio
Signal Point Clinical Research Center, LLC, Middletown, Ohio
Cancer Care Associates, Tulsa, Oklahoma
Providence Oncology & Hematology Care, Portland, Oregon
Kaiser Permanente Northwest, Portland, Oregon
Oregon Health & Science University, Portland, Oregon
Willamette Valley Cancer Center, Springfield, Oregon
Abington Memorial Hospital, Abington, Pennsylvania
St. Luke's Hospital, Bethlehem, Pennsylvania
Oncology Hematology Associates, DuBois, Pennsylvania
Gettysburg Cancer Center, Gettysburg, Pennsylvania
Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania
Western Pennsylvania Hospital, Pittsburgh, Pennsylvania
Medical University of South Carolina, Charleston, South Carolina
Chattanooga's Program in Women's Oncology, Chattanooga, Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee
Texas Oncology, PA, Austin, Texas
Texas Oncology, P.A., Bedford, Texas
Texas Oncology, PA, Dallas, Texas
Baylor Sammons Cancer Center, Dallas, Texas
International Beneficence Clinical Research, L.L.C., Harlingen, Texas
University of Texas Health Science Center at Houston Medical School, Houston, Texas
South Texas Oncology and Hematology, PA, San Antonio, Texas
Scott and White Memorial Hospital, Temple, Texas
US Oncology Research, Wichita Falls, Texas
Northern Utah Associates, Ogden, Utah
Utah Cancer Specialists, Salt Lake City, Utah
Northern Virginia Pelvic Surgery Associates, Annandale, Virginia
Peninsula Cancer Institute - Riverside Gynecology Oncology, Newport News, Virginia
Harrison Bremerton Hematology and Oncology, Bremerton, Washington
Providence Everett Medical Center, Everett, Washington
Cancer Care Northwest-South, Spokane, Washington
Northwest Cancer Specialists, PC, Vancouver, Washington
Aurora Health Care, West Allis, Wisconsin
Hospital Zonal Especializado en Oncología de Lanús, Buenos Aires, Not set
Consultorios Medicos Privados SA, Buenos Aries, Not set
Fundación Sanatorio Güemes, Caba, Not set
Clinica Universitaria Reina Fabiola, Códoba, Not set
Instituto Medico Platense, La Plata, Not set
Centro Oncologico Riojano Integral (CORI), La Rioja, Not set
Hospital Bocalandro, Loma Hermosa, Not set
Centro Oncologico Integral, Mar Del Plata, Not set
CER Instituto Medico, Quilmes, Not set
Centro Médico San Roque, San Miguel de Tucuman, Not set
Centro Medico de Alta Complejidad Cemac, San Salvador de Jujuy, Not set
ISIS Centro Especializado de LUCE SA, Santa Fe, Not set
Tweed Hospital, Tweed Heads, New South Wales
Westmead Hospital, Westmead, New South Wales
The Royal Brisbane and Women's Hospital, Herston, Queensland
Mater Adult Hospital, South Brisbane, Queensland
North Adelaide Oncology Clinical Trials, North Adelaide, South Australia
Sir Charles Gairdner Hospital, Nedlands, Western Australia
Landeskrankenhaus Villach, Villach, Not set
Kaiser-Franz-Josef Spital, Wien, Not set
Krankenhaus Wien-Hietzing, Wien, Not set
Institut Jules Bordet, Bruxelles, Not set
Cliniques Universitaires Saint-Luc, Bruxelles, Not set
UZ Gent, Gent, Not set
AZ Groeninge - Campus Maria's Voorzienigheid, Kortrijk, Not set
UZ Leuven, Leuven, Not set
CHU de Liège, Liège, Not set
Sint-Augustinuskliniek, Wilrijk, Not set
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, Not set
Instituto de Pesquisas Clínicas para Estudos Multicêntricos, Caxias do Sul, Not set
Santa Casa da Misericórdia de Curitiba, Curitiba, Not set
Instituto do Câncer do Ceará - ICC, Fortaleza, Not set
Hosp. Araujo Jorge, Goiania, Not set
Associação Hospital de Caridade Ijuí, Ijuí, Not set
Clinica de Neoplasias Litoral, Itajai, Not set
Hospital Amaral Carvalho, Jaú, Not set
Liga Norte-Riograndense Contra o Câncer, Natal, Not set
Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Not set
Clínica de Oncologia de Porto Alegre S/S Ltda, Porto Alegre, Not set
Instituto Ribeirãopretano de Combate ao Câncer, Ribeirão Preto, Not set
INCA - Instituto Nacional do Câncer, Rio De Janeiro - RJ, Not set
Clínica Oncologistas Associados, Rio de Janeiro, Not set
Hospital Santa Izabel - Santa Casa de Misericordia da Bahia, Salvador, Not set
Clínica AMO - Assistência Multidiciplinar em Oncologia, Salvador, Not set
Centro de Estudos de Oncologia da FMABC, Santo André, Not set
Saúde ABC Serviços Médicos Hospitalares Ltda, Santo André, Not set
Instituto do Câncer Arnaldo Vieira de Carvalho, São Paulo, Not set
Certo Oncologia, São Paulo, Not set
Hospital Premier, São Paulo, Not set
Tom Baker Cancer Centre, Calgary, Alberta
Cancer Center For The Southern Interior, Kelowna, British Columbia
British Columbia Cancer Agency, Surrey, British Columbia
BCCA, Vancouver, British Columbia
The Moncton Hospital, Moncton, New Brunswick
Ottawa Hospital, Ottawa, Ontario
Instituto de Terapias Oncologicas, Santiago, Not set
Instituto Clínico Oncológico del Sur, Temuco, Not set
Instituto Oncologico Ltda., Viña del Mar, Not set
Centre Régional de lutte contre le cancer Paul Papin, Angers Cedex 9, Not set
Centre Hospitalier Louis Pasteur, Le Coudray, Not set
Institut Paoli Calmettes, Marseille, Not set
Hôpital Saint Louis, Paris Cedex 10, Not set
Institut Jean Godinot - Centre de lutte contre le cancer, Reims, Not set
Helios Klinikum Berlin-Buch, Berlin-Buch, Not set
Charité - Universitätsmedizin Berlin, Berlin, Not set
Klinikum Chemnitz gGmbH, Chemnitz, Not set
Marien-Hospital Akademisches Lehrkrankenhaus, Düsseldorf, Not set
Frauenarztpraxis Dr. med. Gröll de Rivera, Ebersberg, Not set
Universitätsklinikum Essen, Essen, Not set
Krankenhaus Nordwest, Frankfurt, Not set
Universitätsklinikum Freiburg, Freiburg, Not set
Kath. Marienkrankenhaus gGmbH, Hamburg, Not set
Universität Heidelberg, Heidelberg, Not set
St. Vincentius Kliniken Karlsruhe, Karlsruhe, Not set
Universitätsklinik Magdeburg, Magdeburg, Not set
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Not set
Klinikum der Universität München - Innenstadt, München, Not set
Rotkreuzklinikum München, München, Not set
Klinikum Südstadt Rostock, Rostock, Not set
Klinikum Traunstein, Traunstein, Not set
University General Hospital of Heraklion, Heraklion, Crete
Alexandra Hospital, Athens, Not set
General Oncology Hospital Kifissias "Oi Agioi Anargyroi", Athens, Not set
University General Hospital of Patras, Patras, Not set
Papageorgiou General Hospital, Thessaloniki, Not set
Queen Mary Hospital, Pokfulam, Islands
Tuen Mun Hospital, Tuen Mun, Not set
Semmelweis Egyetem, Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Petz Aladár Megyei Oktató Kórház, Gyor, Not set
Bács-Kiskun Megyei Önkormányzat Kórháza, Kecskemét, Not set
Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktató Kórház, Miskolc, Not set
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelöintézet, Szolnok, Not set
Veszprém Megyei Önkormányzat Csolnoky Ferenc Kórház-Rendelöintézet, Veszprém, Not set
Apollo Hospitals International Limited, Gandhinagar, Gujarat
Kidwai Memorial Institute of Oncology, Bangalore, Karnataka
Jawaharlal Nehru Cancer Hospital & Research Centre, Bhopal, Madhya Pradesh
Jehangir, Clinical Development Centre, Pune, Maharashtra
Ruby Hall Clinic, Pune, Maharashtra
Dr. Kamakshi Memorial Hospital, Chennai, Tamil Nadu
Chittaranjan National Cancer Institute, Kolkata, West Bengal
M.S Ramaiah Medical College and Teaching Hospital Ethical Review Board, Bangalore, Not set
Amrita Institute of Medical Sciences and Research Centre, Cochin, Not set
MNJ Institute of Oncology and Regional Cancer Centre, Hyderabaad, Not set
SK Soni Hospital, Jaipur, Not set
Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Not set
Lakeshore Hospital, Kochi, Not set
Tata Memorial Hospital, Mumbai, Not set
Shatabdi Superspeciality Hospital, Nashik, Not set
Curie Manavata Cancer Centre, Nasik, Not set
All India Institute of Medical Sciences, New Delhi, Not set
Regional Cancer Centre, Trivandrum, Not set
Rambam Medical Center, Haifa, Not set
Linn Medical Center, Clalit Health Services, Haifa, Not set
Wolfson Centre, Holon, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah University Hospital Ein Kerem, Jerusalem, Not set
Meir Medical Center, Kfar Saba, Not set
Rabin Medical Center, Petach Tikva, Not set
The Chaim Sheba Medical Center, Ramat-Gan, Not set
Kaplan Medical Center, Rehovot, Not set
Assaf Harofe Medical Center, Zerifin, Not set
Centro di Riferimento Oncologico, Aviano, Pordenone
Azienda Ospedaliera Santi Antonio, Biagio e Cesare Arrigo, Alessandria, Not set
Azienda Ospedaliero-Universitaria di Bologna - Policlinico S.Orsola-Malpighi, Bologna, Not set
Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Not set
Centro di Ricerca e Formazione ad Alta Tecnologia nelle Scienze Biomediche, Campobasso, Not set
Azienda Ospedaliera Cannizzaro, Catania, Not set
Humanitas Centro Catanese di Oncologia, Catania, Not set
Azienda Ospedaliera Sant'Anna, Como, Not set
Ospedale di Faenza, Faenza, Not set
Azienda Ospedaliera Universitaria San Martino, Genova, Not set
Presidio Ospedaliero Vito Fazzi, Lecce, Not set
Ospedale Mater Salutis ULSS 21 della regione Veneto, Legnago, Not set
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori - IRST, Meldola, Not set
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Not set
Fondazione Centro San Raffaele del Monte Tabor, Milano, Not set
Istituto Nazionale dei Tumori, Milano, Not set
Azienda Ospedaliera Niguarda Cà Granda, Milano, Not set
Istituto Nazionale per lo studio e la cura dei tumori "Fondazione Giovanni Pascale", Napoli, Not set
Ospedale Sacro Cuore Don Calabria, Negrar, Not set
Istituto Oncologico Veneto, Padova, Not set
Ospedale Santa Maria della Misericordia di Perugia, Perugia, Not set
Ospedale Santa Maria delle Croci, Ravenna, Not set
Arcispedale Santa Maria Nuova, Reggio Emilia, Not set
Azienda Policlinico Umberto I, Roma, Not set
Policlinico Universitario "A. Gemelli", Roma, Not set
Azienda Ospedaliero-Universitaria di Udine, Udine, Not set
Not set, Akashi, Not set
Not set, Amagasaki, Not set
Not set, Chiba, Not set
Not set, Fukuoka, Not set
Not set, Hidaka, Not set
Not set, Hiroshima, Not set
Not set, Kagoshima, Not set
Not set, Kashiwa, Not set
Not set, Kawasaki, Not set
Not set, Koto-Ku, Not set
Not set, Kumamoto, Not set
Not set, Kure, Not set
Not set, Kurume, Not set
Not set, Matsuyama, Not set
Not set, Minato-Ku, Not set
Not set, Morioka, Not set
Not set, Nagoya, Not set
Not set, Nakano-Ku, Not set
Not set, Niigata, Not set
Not set, Okayama, Not set
Not set, Osakasayama, Not set
Not set, Osaka, Not set
Not set, Sapporo, Not set
Not set, Sendai, Not set
Not set, Shinjuku-Ku, Not set
Not set, Sunto-Gun, Not set
Not set, Tsukuba, Not set
Not set, Tsu, Not set
Not set, Yamagata, Not set
Not set, Yonago, Not set
National Cancer Center, Gyeonggi-do, Not set
Gachon University Gil Medical Center, In Cheon, Not set
Cheil General Hospital & Women's Healthcare Center, Seoul, Not set
Seoul national univercity hospital, Seoul, Not set
Severance Hospital, Yonsei University College of Medicine, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Union Medica Quirurgica de Colima, Colima, Not set
Triva Investigaciones Medicas Sociedad Anónima de Capital Variable, Morelia, Not set
Hospital Regional de Veracruz, Veracruz, Not set
VU Medisch Centrum, Amsterdam, Not set
Albert Schweitzer Ziekenhuis, Dordrecht, Not set
Academisch Ziekenhuis Maastricht, Maastricht, Not set
Orbis Medisch Centrum, Sittard-Geleen, Not set
Perpetual Succour Hospital, Cebu City, Cebu
Cebu Gynecologic Cancer Care Clinic, Cebu, Not set
Manila Doctors Hospital, Manila, Not set
San Juan de Dios Hospital, Pasay City, Not set
St. Luke's Medical Center, Quezon City, Not set
National Kidney and Transplant Institute, Quezon City, Not set
Bialostockie Centrum Onkologii, Bialystok, Not set
Wojewodzkie Centrum Onkologii, Gdansk, Not set
Centrum Onkologii, Instytut im. M. Sklodowskiej-Curie oddzial w Gliwicach, Gliwice, Not set
Wojewodzki Szpital Specjalistyczny im. M. Kopernika w Lodzi, Lodz, Not set
Centrum Onkologii Ziemi Lubelskiej, Lublin, Not set
Zaklad Opieki Zdrowotnej MSWiA z Warminsko-Mazurskim Centrum Onkologii, Olsztyn, Not set
Olsztynski Osrodek Onkologiczny "Kopernik" Sp. z o.o., Olsztyn, Not set
Wielkopolskie Centrum Onkologii, Poznan, Not set
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Pozna, Poznan, Not set
SPZOZ Wojewodzki Szpital Specjalistyczny nr 3, Rybnik, Not set
Samodzielny Publiczny Szpital Kliniczny nr 2 PAM w Szczecinie, Szczecin, Not set
Wojskowy Instytut Medyczny, Warszawa, Not set
Hospitais da Universidade de Coimbra, Coimbra, Not set
Instituto Português de Oncologia Francisco Gentil, Centro Regional de Oncologia de Coimbra, EPE, Coimbra, Not set
Instituto Portugues de Oncologia de Lisboa Francisco Gentil (IPOLFG, EPE), Lisboa, Not set
Instituto Portugues de Oncologia do Porto Francisco Gentil (IPOPFG, EPE), Porto, Not set
Hospital de São João, Porto, Not set
Kursk Regional Oncology Centre, Kursk, Not set
Russian Oncology Research Center named after N.N. Blokhin, Moscow, Not set
Russian Oncology Research Center, Moscow, Not set
Moscow Research Oncology Institute n.a. P.A.Gertsen, Moscow, Not set
Medical Radiology Research Center of RAMS, Obninsk, Not set
Ryazan Regional Clinical Oncology Dispensary, Ryazan, Not set
City Clinical Oncology Dispensary, St. Petersburg, Not set
Republican Clinical Oncology Center of Bashkortostan Republic Ministry of Healthcare, Ufa, Not set
National University Hospital, Singapore, Not set
National Cancer Centre, Singapore, Not set
KK Women's and Children's Hospital, Singapore, Not set
Hospital Universitario Reina Sofia, Córdoba, Andalucía
Hospital Virgen del Rocio, Sevilla, Andalucía
Hospital Son Llatzer, Palma de Mallorca, Baleares
Hospital Universitario Vall D'Hebron, Barcelona, Cataluna
Hospital Clinic i Provincial, Barcelona, Cataluña
Hospital de Mataró, Mataró, Cataluña
Corporació Sanitaria Parc Taulí, Sabadell, Cataluña
Hospital Mutua de Terrassa, Terrassa, Cataluña
Hospital General Universitario de Elche, Elche, Comunidad Valenciana
Fundación Instituto Valenciano de Oncología, Valencia, Comunidad Valenciana
Fundacion Hospital Alcorcon, Alcorcón, Madrid, Communidad De
Hospital General Universitario Gregorio Marañon, Madrid, Madrid, Communidad De
Hospital Universitario Ramón y Cajal, Madrid, Madrid, Communidad De
Hospital 12 de Octubre, Madrid, Madrid, Communidad De
Hospital Clinico San Carlos, Madrid, Not set
Universität Zürich, Zürich, Not set
National Cheng Kung University Hosptial, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
Mackay Memorial Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Chang Gung Memorial Hospital, Taoyuan, Not set
Municipal Institution of Cherkasy Regional Counsil "Cherkasy Regional Oncology Dispensary", Cherkasy, Not set
Chernivtsi Regional Clinical Oncology Dispansery, Chernivtsi, Not set
Kiev City Oncology Hospital, Kyiv, Not set
Volyn Regional Oncology Dispensary, Lutsk, Not set
Belfast City Hospital, Belfast, Not set
Velindre Hospital, Cardiff, Not set
University Hospital Coventry, Coventry, Not set
Ninewells Hospital, Dundee, Not set
Beatson Oncology Centre, Glasgow, Not set
Leicester Royal Infirmary, Leicester, Not set
Royal Marsden Hospital, London, Not set
Hammersmith Hospital, London, Not set
Derriford Hospital, Plymouth, Not set
Poole Hospital NHS Trust, Poole, Not set
Weston Park Hospital, Sheffield, Not set
Clatterbridge Centre For Oncology, Wirral, Not set
New Cross Hospital, Wolverhampton, Not set
Conditions: Ovarian Cancer
A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma
Terminated
The purpose of this study is to confirm that the pharmacokinetics of ibrutinib in pediatric participants is consistent with that in adults (part 1) and to assess efficacy (event-free survival \[EFS\]) of ibrutinib in combination with rituximab, ifosfamide, carboplatin, and etoposide (RICE) or rituximab, vincristine, ifosfamide, carboplatin, and idarubicin (RVICI) background therapy compared to RICE or RVICI background therapy alone (part 2).
The purpose of this study is to confirm that the pharmacokinetics of ibrutinib in pediatric participants is consistent with that in adults (part 1) and to assess efficacy (event-free survival \[EFS\]) of ibrutinib in combination with rituximab, ifosfamide, carboplatin, and etoposide (RICE) or rituximab, vincristine, ifosfamide, carboplatin, and idarubicin (RVICI) background therapy compared to RICE or RVICI background therapy alone (part 2). Read Less
Gender:
ALL
Ages:
Between 1 year and 30 years
Trial Updated:
11/07/2022
Locations: Not set, Los Angeles, California +76 locations
Not set, Los Angeles, California
Not set, Orange, California
Not set, Palo Alto, California
Not set, Aurora, Colorado
Not set, Washington, District of Columbia
Not set, Atlanta, Georgia
Not set, Baltimore, Maryland
Not set, Boston, Massachusetts
Not set, New York, New York
Not set, Valhalla, New York
Not set, Charlotte, North Carolina
Not set, Cincinnati, Ohio
Not set, Columbus, Ohio
Not set, Philadelphia, Pennsylvania
Not set, Dallas, Texas
Not set, Salt Lake City, Utah
Not set, Milwaukee, Wisconsin
Not set, Brussel, Not set
Not set, Leuven, Not set
Not set, Barretos, Not set
Not set, Curitiba, Not set
Not set, Sao Paulo, Not set
Not set, São Paulo, Not set
Not set, Plovdiv, Not set
Not set, Sofia, Not set
Not set, Halifax, Nova Scotia
Not set, Toronto, Ontario
Not set, Brno, Not set
Not set, Praha, Not set
Not set, Bordeaux, Not set
Not set, Lille, Not set
Not set, Lyon, Not set
Not set, Marseille, Not set
Not set, Nantes, Not set
Not set, Toulouse, Not set
Not set, Vandoeuvre les Nancy, Not set
Not set, Villejuif, Not set
Not set, Berlin, Not set
Not set, Freiburg, Not set
Not set, Kiel, Not set
Not set, München, Not set
Not set, Münster, Not set
Not set, Budapest, Not set
Not set, Debrecen, Not set
Not set, Seoul, Not set
Not set, Rotterdam, Not set
Not set, Utrecht, Not set
Not set, Krakow, Not set
Not set, Warszawa, Not set
Not set, Wroclaw, Not set
Not set, Bucuresti, Not set
Not set, Cluj-Napoca, Not set
Not set, Oradea, Not set
Not set, Timisoara, Not set
Not set, Ekaterinburg, Not set
Not set, Moscow, Not set
Not set, St. Petersburg, Not set
Not set, Barcelona, Not set
Not set, Esplugues de Llobregat, Not set
Not set, Madrid, Not set
Not set, Valencia, Not set
Not set, Gothenburg, Not set
Not set, Kaohsiung, Not set
Not set, Taipei, Not set
Not set, Taoyuan, Not set
Not set, Ankara, Not set
Not set, Izmir, Not set
Not set, Kiev, Not set
Not set, Birmingham, Not set
Not set, Cambridge, Not set
Not set, Leeds, Not set
Not set, Liverpool, Not set
Not set, London, Not set
Not set, Manchester, Not set
Not set, Newcastle, Not set
Not set, Sheffield, Not set
Not set, Surrey, Not set
Conditions: Lymphoma, Non-Hodgkin
Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer
Completed
This randomized phase III trial studies how well giving cisplatin and radiation therapy together with or without carboplatin and paclitaxel works in treating patients with cervical cancer has spread from where it started to nearby tissue or lymph nodes. Drugs used in chemotherapy, such as cisplatin, carboplatin, and paclitaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Exte... Read More
This randomized phase III trial studies how well giving cisplatin and radiation therapy together with or without carboplatin and paclitaxel works in treating patients with cervical cancer has spread from where it started to nearby tissue or lymph nodes. Drugs used in chemotherapy, such as cisplatin, carboplatin, and paclitaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. External radiation therapy uses high-energy x rays to kill tumor cells. Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells. It is not yet known whether giving cisplatin and external and internal radiation therapy together with carboplatin and paclitaxel kills more tumor cells. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/27/2022
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +325 locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
University of South Alabama Mitchell Cancer Institute, Mobile, Alabama
Alaska Women's Cancer Care, Anchorage, Alaska
Providence Alaska Medical Center, Anchorage, Alaska
Cancer Center at Saint Joseph's, Phoenix, Arizona
Gynecologic Oncology Group of Arizona, Phoenix, Arizona
Saint Joseph's Hospital and Medical Center, Phoenix, Arizona
Arizona Oncology Associates-Biltmore Cancer Center, Phoenix, Arizona
Arizona Oncology Associates-West Orange Grove, Tucson, Arizona
Arizona Oncology Associates-Wilmot, Tucson, Arizona
University of Arkansas for Medical Sciences, Little Rock, Arkansas
Sutter Auburn Faith Hospital, Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Mills-Peninsula Medical Center, Burlingame, California
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California
John Muir Medical Center-Concord Campus, Concord, California
Sutter Davis Hospital, Davis, California
Kaiser Permanente-Fremont, Fremont, California
Memorial Medical Center, Modesto, California
Palo Alto Medical Foundation-Camino Division, Mountain View, California
Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California
Kaiser Permanente-Oakland, Oakland, California
Saint Joseph Hospital - Orange, Orange, California
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California
Palo Alto Medical Foundation Health Care, Palo Alto, California
Kaiser Permanente-Roseville, Roseville, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Roseville Medical Center, Roseville, California
Mercy Cancer Center - Sacramento, Sacramento, California
Sutter Medical Center Sacramento, Sacramento, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
California Pacific Medical Center-Pacific Campus, San Francisco, California
Kaiser Permanente-San Francisco, San Francisco, California
Kaiser Permanente-San Rafael, San Rafael, California
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California
Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California
Sutter Pacific Medical Foundation, Santa Rosa, California
Kaiser Permanente-South San Francisco, South San Francisco, California
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California
Olive View-University of California Los Angeles Medical Center, Sylmar, California
Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California
Kaiser Permanente-Vallejo, Vallejo, California
Sutter Solano Medical Center/Cancer Center, Vallejo, California
John Muir Medical Center-Walnut Creek, Walnut Creek, California
Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado
The Medical Center of Aurora, Aurora, Colorado
University of Colorado Hospital, Aurora, Colorado
Boulder Community Hospital, Boulder, Colorado
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado
Porter Adventist Hospital, Denver, Colorado
Colorado Blood Cancer Institute, Denver, Colorado
Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado
Rocky Mountain Cancer Centers-Midtown, Denver, Colorado
SCL Health Saint Joseph Hospital, Denver, Colorado
Rocky Mountain Cancer Centers-Rose, Denver, Colorado
Rose Medical Center, Denver, Colorado
Western States Cancer Research NCORP, Denver, Colorado
Southwest Oncology PC, Durango, Colorado
Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado
Swedish Medical Center, Englewood, Colorado
North Colorado Medical Center, Greeley, Colorado
Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado
Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado
Saint Anthony Hospital, Lakewood, Colorado
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado
Littleton Adventist Hospital, Littleton, Colorado
Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado
Sky Ridge Medical Center, Lone Tree, Colorado
Longmont United Hospital, Longmont, Colorado
Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado
McKee Medical Center, Loveland, Colorado
Parker Adventist Hospital, Parker, Colorado
Rocky Mountain Cancer Centers-Parker, Parker, Colorado
Saint Mary Corwin Medical Center, Pueblo, Colorado
Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado
Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado
SCL Health Lutheran Medical Center, Wheat Ridge, Colorado
University of Connecticut, Farmington, Connecticut
Hartford Hospital, Hartford, Connecticut
The Hospital of Central Connecticut, New Britain, Connecticut
Yale University, New Haven, Connecticut
Christiana Care Health System-Christiana Hospital, Newark, Delaware
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Jackson Memorial Hospital-Holtz Children's Hospital, Miami, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Orlando Health Cancer Institute, Orlando, Florida
Sarasota Memorial Hospital, Sarasota, Florida
Grady Health System, Atlanta, Georgia
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia
Central Georgia Gynecologic Oncology, Macon, Georgia
The Cancer Center of Hawaii-Pali Momi, 'Aiea, Hawaii
Queen's Medical Center, Honolulu, Hawaii
University of Hawaii Cancer Center, Honolulu, Hawaii
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Cancer Clinic, Sandpoint, Idaho
Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho
Saint Joseph Medical Center, Bloomington, Illinois
Illinois CancerCare-Bloomington, Bloomington, Illinois
Illinois CancerCare-Canton, Canton, Illinois
Illinois CancerCare-Carthage, Carthage, Illinois
Centralia Oncology Clinic, Centralia, Illinois
Northwestern University, Chicago, Illinois
John H Stroger Jr Hospital of Cook County, Chicago, Illinois
Rush University Medical Center, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Crossroads Cancer Center, Effingham, Illinois
Illinois CancerCare-Eureka, Eureka, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
Illinois CancerCare-Galesburg, Galesburg, Illinois
Western Illinois Cancer Treatment Center, Galesburg, Illinois
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
Sudarshan K Sharma MD Limited-Gynecologic Oncology, Hinsdale, Illinois
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois
Illinois CancerCare-Macomb, Macomb, Illinois
Loyola University Medical Center, Maywood, Illinois
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois
Illinois CancerCare-Peoria, Peoria, Illinois
OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois
Methodist Medical Center of Illinois, Peoria, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
Illinois CancerCare-Peru, Peru, Illinois
Valley Radiation Oncology, Peru, Illinois
Illinois CancerCare-Princeton, Princeton, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Memorial Medical Center, Springfield, Illinois
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana
Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana
Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana
The Community Hospital, Munster, Indiana
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kansas Cancer Center, Kansas City, Kansas
Baptist Health Lexington, Lexington, Kentucky
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Norton Hospital Pavilion and Medical Campus, Louisville, Kentucky
Norton Brownsboro Hospital and Medical Campus, Louisville, Kentucky
Woman's Hospital, Baton Rouge, Louisiana
Louisiana State University Health Science Center, New Orleans, Louisiana
Tulane University Health Sciences Center, New Orleans, Louisiana
University Medical Center New Orleans, New Orleans, Louisiana
Ochsner Medical Center Jefferson, New Orleans, Louisiana
Maine Medical Center-Bramhall Campus, Portland, Maine
Maine Medical Center- Scarborough Campus, Scarborough, Maine
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
Walter Reed National Military Medical Center, Bethesda, Maryland
Baystate Medical Center, Springfield, Massachusetts
UMass Memorial Medical Center - Memorial Division, Worcester, Massachusetts
Saint Joseph Mercy Hospital, Ann Arbor, Michigan
Bronson Battle Creek, Battle Creek, Michigan
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Hospital, Detroit, Michigan
Cancer Research Consortium of West Michigan NCORP, Grand Rapids, Michigan
Mercy Health Saint Mary's, Grand Rapids, Michigan
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
Sparrow Hospital, Lansing, Michigan
William Beaumont Hospital-Royal Oak, Royal Oak, Michigan
Munson Medical Center, Traverse City, Michigan
Mercy Hospital, Coon Rapids, Minnesota
Fairview Southdale Hospital, Edina, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
United Hospital, Saint Paul, Minnesota
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Mercy Hospital Springfield, Springfield, Missouri
CoxHealth South Hospital, Springfield, Missouri
Billings Clinic Cancer Center, Billings, Montana
Saint Vincent Healthcare, Billings, Montana
Bozeman Deaconess Hospital, Bozeman, Montana
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana
Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana
Saint Peter's Community Hospital, Helena, Montana
Kalispell Regional Medical Center, Kalispell, Montana
Saint Patrick Hospital - Community Hospital, Missoula, Montana
Nebraska Methodist Hospital, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Women's Cancer Center of Nevada, Las Vegas, Nevada
Wentworth-Douglass Hospital, Dover, New Hampshire
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Cooper Hospital University Medical Center, Camden, New Jersey
Hackensack University Medical Center, Hackensack, New Jersey
Morristown Medical Center, Morristown, New Jersey
Virtua Memorial, Mount Holly, New Jersey
Jersey Shore Medical Center, Neptune, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
MD Anderson Cancer Center at Cooper-Voorhees, Voorhees, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Southwest Gynecologic Oncology Associates Inc, Albuquerque, New Mexico
Lovelace Radiation Oncology, Albuquerque, New Mexico
Memorial Medical Center - Las Cruces, Las Cruces, New Mexico
Women's Cancer Care Associates LLC, Albany, New York
Montefiore Medical Center-Einstein Campus, Bronx, New York
State University of New York Downstate Medical Center, Brooklyn, New York
New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York
Roswell Park Cancer Institute, Buffalo, New York
Memorial Sloan Kettering Commack, Commack, New York
New York Hospital Medical Center of Queens, Fresh Meadows, New York
Memorial Sloan Kettering Westchester, Harrison, New York
Queens Hospital Center, Jamaica, New York
Northwell Health/Center for Advanced Medicine, Lake Success, New York
North Shore University Hospital, Manhasset, New York
NYU Winthrop Hospital, Mineola, New York
Long Island Jewish Medical Center, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Lenox Hill Hospital, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Highland Hospital, Rochester, New York
University of Rochester, Rochester, New York
Memorial Sloan Kettering Sleepy Hollow, Sleepy Hollow, New York
Stony Brook University Medical Center, Stony Brook, New York
Memorial Sloan Kettering Nassau, Uniondale, New York
Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina
New Hanover Regional Medical Center/Zimmer Cancer Center, Wilmington, North Carolina
Southeast Clinical Oncology Research Consortium NCORP, Winston-Salem, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Summa Health System - Akron Campus, Akron, Ohio
University of Cincinnati/Barrett Cancer Center, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Miami Valley Hospital, Dayton, Ohio
Kettering Medical Center, Kettering, Ohio
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
University of Toledo, Toledo, Ohio
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma
Providence Portland Medical Center, Portland, Oregon
Abington Memorial Hospital, Abington, Pennsylvania
Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania
Drexel University School of Medicine, Philadelphia, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania
West Penn Hospital, Pittsburgh, Pennsylvania
UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Women and Infants Hospital, Providence, Rhode Island
AnMed Health Cancer Center, Anderson, South Carolina
Medical University of South Carolina, Charleston, South Carolina
Gibbs Cancer Center-Gaffney, Gaffney, South Carolina
Saint Francis Hospital, Greenville, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
MGC Hematology Oncology-Union, Union, South Carolina
Black Hills Obstetrics and Gynecology, Rapid City, South Dakota
Rapid City Regional Hospital, Rapid City, South Dakota
Texas Oncology-Austin Midtown, Austin, Texas
Texas Oncology - Central Austin Cancer Center, Austin, Texas
Texas Oncology - South Austin Cancer Center, Austin, Texas
Texas Oncology Bedford, Bedford, Texas
Texas Oncology at Baylor Charles A Sammons Cancer Center, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Texas Oncology - Fort Worth Cancer Center, Fort Worth, Texas
University of Texas Medical Branch, Galveston, Texas
Lyndon Baines Johnson General Hospital, Houston, Texas
Houston Methodist Hospital, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Memorial Hermann Texas Medical Center, Houston, Texas
West Texas Cancer Center, Odessa, Texas
Houston Methodist Sugar Land Hospital, Sugar Land, Texas
Intermountain Medical Center, Murray, Utah
Dixie Medical Center Regional Cancer Center, Saint George, Utah
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah
LDS Hospital, Salt Lake City, Utah
University of Virginia Cancer Center, Charlottesville, Virginia
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia
Carilion Clinic Gynecological Oncology, Roanoke, Virginia
MultiCare Auburn Medical Center, Auburn, Washington
MultiCare Gig Harbor Medical Park, Gig Harbor, Washington
MultiCare Good Samaritan Hospital, Puyallup, Washington
MultiCare Tacoma General Hospital, Tacoma, Washington
Aurora BayCare Medical Center, Green Bay, Wisconsin
University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin
Aurora West Allis Medical Center, West Allis, Wisconsin
Cheyenne Regional Medical Center-West, Cheyenne, Wyoming
Billings Clinic-Cody, Cody, Wyoming
Welch Cancer Center, Sheridan, Wyoming
Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario
London Regional Cancer Program, London, Ontario
University Health Network-Princess Margaret Hospital, Toronto, Ontario
CHUM - Hopital Notre-Dame, Montreal, Quebec
McGill University Department of Oncology, Montreal, Quebec
CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec
The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec
Allan Blair Cancer Centre, Regina, Saskatchewan
Zhongshan Hospital Fudan University, Guangdong Province, Shanghai
King Faisal Specialist Hospital and Research Centre, Riyadh, Not set
National University Hospital Singapore, Singapore, Not set
Conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Stage IB Cervical Cancer AJCC v6 and v7, Stage IIA Cervical Cancer AJCC v7, Stage IIB Cervical Cancer AJCC v6 and v7, Stage IIIB Cervical Cancer AJCC v6 and v7, Stage IVA Cervical Cancer AJCC v6 and v7
A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)
Completed
The purpose of this study is to assess the safety and efficacy of pembrolizumab plus standard of care (SOC) chemotherapy (etoposide/platinum \[EP\]) in participants with newly diagnosed extensive stage small cell lung cancer (ES-SCLC) who have not previously received systemic therapy for this malignancy.
The primary study hypotheses are that pembrolizumab+EP prolongs Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 by blinded independent cent... Read More
The purpose of this study is to assess the safety and efficacy of pembrolizumab plus standard of care (SOC) chemotherapy (etoposide/platinum \[EP\]) in participants with newly diagnosed extensive stage small cell lung cancer (ES-SCLC) who have not previously received systemic therapy for this malignancy.
The primary study hypotheses are that pembrolizumab+EP prolongs Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 by blinded independent central review (BICR) and Overall Survival (OS) compared with placebo+EP in adult participants with ES-SCLC. In this study, RECIST 1.1 has been modified to follow a maximum of 10 target lesions and a maximum of 5 target lesions per organ.
With protocol Amendment 07 (03-Oct-2018), the outcome measure of "Change from Baseline at Weeks 12 and 24 in European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30) Global Health Status/Quality of Life Scale" was replaced with a single time point analysis at Week 18. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/02/2022
Locations: Baptist Health Medical Group Oncology, LLC ( Site 8000), Miami, Florida +147 locations
Baptist Health Medical Group Oncology, LLC ( Site 8000), Miami, Florida
Rush University Medical Center ( Site 1215), Chicago, Illinois
North Shore University Health System ( Site 1216), Evanston, Illinois
Community Hospital ( Site 1207), Munster, Indiana
Weinberg Cancer Institute at Franklin Square ( Site 1210), Baltimore, Maryland
Massachusetts General Hospital ( Site 1203), Boston, Massachusetts
Beth Israel Deaconess Medical Center ( Site 1206), Boston, Massachusetts
Dana-Farber Cancer Institute [Boston] ( Site 1201), Boston, Massachusetts
University of Michigan ( Site 1217), Ann Arbor, Michigan
Henry Ford Health System ( Site 1221), Detroit, Michigan
Minnesota Oncology Hematology, PA ( Site 8001), Minneapolis, Minnesota
Hattiesburg Clinic ( Site 1205), Hattiesburg, Mississippi
Mercy Hospital Saint Louis ( Site 1213), Saint Louis, Missouri
Comprehensive Cancer Centers of Nevada ( Site 8004), Henderson, Nevada
Memorial Sloan-Kettering Cancer Center At Basking Ridge ( Site 1226), Basking Ridge, New Jersey
Memorial Sloan Kettering Cancer Center- Monmouth ( Site 1225), Middletown, New Jersey
Montefiore Einstein Center for Cancer Care - Main site ( Site 1204), Bronx, New York
Montefiore Medical Center ( Site 1222), Bronx, New York
Memorial Sloan-Kettering Cancer Center at Commack ( Site 1227), Commack, New York
Memorial Sloan Kettering Cancer Center ( Site 1229), Harrison, New York
Memorial Sloan Kettering Cancer Center ( Site 1211), New York, New York
Memorial Sloan Kettering Cancer Center - Rockville Centre ( Site 1228), Rockville Centre, New York
Duke University Medical Center ( Site 1214), Durham, North Carolina
Bon Secours St. Francis Health Sytem ( Site 1212), Greenville, South Carolina
Tennessee Oncology, PLLC/The Sarah Cannon Research Institute ( Site 1230), Nashville, Tennessee
Texas Oncology ( Site 8002), Austin, Texas
Texas Oncology-Baylor Charles A. Sammons Cancer Center ( Site 8003), Dallas, Texas
Blacktown Hospital ( Site 0004), Blacktown, New South Wales
Southern Medical Day Care Centre ( Site 0001), Wollongong, New South Wales
St John of God ( Site 0006), Murdoch, Western Australia
Lyell McEwin Hospital ( Site 0002), Elizabeth Vale, Not set
St Vincents Hospital Melbourne ( Site 0005), Fitzroy, Not set
Cancer Care Manitoba ( Site 0159), Winnipeg, Manitoba
Nova Scotia Health Authority ( Site 0157), Halifax, Nova Scotia
William Osler Health System (Brampton Civic Hospital) ( Site 0161), Brampton, Ontario
Kingston Health Sciences Centre ( Site 0155), Kingston, Ontario
Sunnybrook Research Institute ( Site 0151), Toronto, Ontario
CISSS de la Monteregie-Centre ( Site 0152), Greenfield Park, Quebec
CISSS-CA Hotel Dieu de Levis ( Site 0154), Lévis, Quebec
CIUSSS Ouest de l'Ile - St-Mary's Hospital ( Site 0158), Montreal, Quebec
St. Jerome Medical Research Inc. ( Site 0160), St-Jerome, Quebec
Instituto Nacional del Cancer ( Site 0207), Santiago, Region Metropolitana
Health and Care Chile ( Site 0202), Santiago, Not set
Fundacion Arturo Lopez Perez FALP ( Site 0203), Santiago, Not set
Pontificia Universidad Catolica de Chile ( Site 0206), Santiago, Not set
Clinica Universidad Catolica del Maule ( Site 0208), Talca, Not set
CHRU de Lille - Hopital Albert Calmette ( Site 0353), Lille, Not set
C.H.R.U. De Limoges ( Site 0358), Limoges, Not set
CHU Nantes - Hopital Laennec ( Site 0363), Nantes, Not set
Centre Antoine Lacassagne ( Site 0362), Nice, Not set
Hopital Tenon ( Site 0360), Paris, Not set
Institut de Cancerologie Jean-Godinot ( Site 0351), Reims, Not set
CHU de Toulouse - Hopital Larrey ( Site 0354), Toulouse, Not set
Evangelische Lungenklinik Berlin ( Site 0403), Berlin, Not set
Medizinische Fakultaet Carl Gustav Carus der TU Dresden ( Site 0411), Dresden, Not set
Florence Nightingale Krankenhaus ( Site 0413), Duesseldorf, Not set
SRH Waldklinikum Gera GmbH ( Site 0405), Gera, Not set
Asklepios Klinikum Harburg ( Site 0412), Hamburg, Not set
Thoraxklinik Heidelberg gGmbH am Universitaetsklinikum Heidelberg ( Site 0401), Heidelberg, Not set
Philipps-Universitat Marburg ( Site 0414), Marburg, Not set
Universitaetsklinikum Tuebingen ( Site 0404), Tuebingen, Not set
Orszagos Onkologiai Intezet ( Site 0453), Budapest, Pest
Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0452), Budapest, Not set
Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0458), Budapest, Not set
Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0459), Budapest, Not set
Veszprem Megyei Tudogyogyintezet ( Site 0454), Farkasgyepu, Not set
Petz Aladar Megyei Oktato Korhaz ( Site 0460), Gyor, Not set
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz ( Site 0456), Szekesfehervar, Not set
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 0451), Szolnok, Not set
Zala Megyei Szent Rafael Korhaz ( Site 0457), Zalaegerszeg, Not set
St Vincents University Hospital ( Site 1456), Dublin, Not set
St James Hospital ( Site 1452), Dublin, Not set
Soroka Medical Center ( Site 0505), Beer Sheva, Not set
Ramban Medical Center - Dept. Hemato. & B. Marrow Transplant ( Site 0502), Haifa, Not set
Meir Medical Center ( Site 0503), Kfar Saba, Not set
Rabin Medical Center ( Site 0504), Petah Tikva, Not set
Chaim Sheba Medical Center. ( Site 0501), Ramat-Gan, Not set
National Hospital Organization Nagoya Medical Center ( Site 0615), Nagoya, Aichi
National Cancer Center Hospital East ( Site 0613), Kashiwa, Chiba
National Hospital Organization Shikoku Cancer Center ( Site 0614), Matsuyama, Ehime
Kurume University Hospital ( Site 0609), Kurume, Fukuoka
Hyogo Cancer Center ( Site 0611), Akashi, Hyogo
Kanagawa Cancer Center ( Site 0618), Yokohama, Kanagawa
Sendai Kousei Hospital ( Site 0602), Sendai, Miyagi
National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0608), Sakai, Osaka
Shizuoka Cancer Center Hospital and Research Institute ( Site 0607), Sunto-gun, Shizuoka
National Hospital Organization Yamaguchi Ube Medical Center ( Site 0601), Ube, Yamaguchi
National Hospital Organization Kyushu Medical Center ( Site 0617), Fukuoka, Not set
Hiroshima University Hospital ( Site 0604), Hiroshima, Not set
Niigata Cancer Center Hospital ( Site 0610), Niigata, Not set
Osaka International Cancer Institute ( Site 0616), Osaka, Not set
The Cancer Institute Hospital of JFCR ( Site 0606), Tokyo, Not set
Wakayama Medical University Hospital ( Site 0612), Wakayama, Not set
Inje University Haeundae Paik Hospital ( Site 0905), Busan, Not set
National Cancer Center ( Site 0904), Goyang-si, Not set
Severance Hospital Yonsei University Health System ( Site 0903), Seoul, Not set
Asan Medical Center ( Site 0901), Seoul, Not set
Samsung Medical Center ( Site 0902), Seoul, Not set
Canterbury Regional Cancer & Blood Services ( Site 0701), Christchurch, Not set
Mazowiecki Szpital Onkologiczny ( Site 0757), Wieliszew, Mazowieckie
Przychodnia Lekarska Komed ( Site 0769), Konin, Not set
Krakowski Szpital Specjalistyczny im. Jana Pawla II ( Site 0768), Krakow, Not set
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli ( Site 0767), Lublin, Not set
SKPP UM im. Karola Marcinkowkiego w Poznaniu ( Site 0766), Poznan, Not set
Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 0762), Poznan, Not set
Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu ( Site 0756), Torun, Not set
Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie ( Site 0751), Warszawa, Not set
Dolnoslaskie Centrum Onkologii we Wroclawiu ( Site 0771), Wroclaw, Not set
Belgorod Regional Oncology Dispensary ( Site 0804), Belgorod, Not set
N.N. Blokhin NMRCO ( Site 0801), Moscow, Not set
SBI of Stavropol region Pyatigorskiy Oncologic dispensary ( Site 0811), Pyatigorsk, Not set
SBHI Leningrad Regional Clinical Hospital ( Site 0803), Saint Petersburg, Not set
Municipal Clinical Oncology Center ( Site 0802), Saint Petersburg, Not set
Hospital Universitario Insular de Gran Canaria ( Site 0952), Las Palmas de Gran Canaria, Gran Canaria
Complejo Hospitalario Universitario de A Coruna ( Site 0953), A Coruna, Not set
Hospital del Mar ( Site 0956), Barcelona, Not set
Hospital Universitari Vall d Hebron ( Site 0951), Barcelona, Not set
Hospital Ciudad de Jaen ( Site 0957), Jaen, Not set
Hospital General Universitario Gregorio Maranon ( Site 0958), Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz ( Site 0954), Madrid, Not set
Hospital Clinico Universitario de Valencia ( Site 0955), Valencia, Not set
Kantonsspital Graubuenden ( Site 1403), Chur, Not set
CHUV Centre Hospitalier Universitaire Vaudois ( Site 1405), Lausanne, Not set
Universitaetsspital Zuerich ( Site 1404), Zuerich, Not set
Kaohsiung Chang Gung Memorial Hospital of the C.G.M.F. ( Site 1005), Kaohsiung, Not set
China Medical University Hospital. ( Site 1003), Taichung, Not set
Taichung Veterans General Hospital ( Site 1007), Taichung, Not set
National Cheng Kung University Hospital ( Site 1004), Tainan, Not set
Chi Mei Medical Center Liuying ( Site 1006), Tainan, Not set
National Taiwan University Hospital ( Site 1001), Taipei, Not set
Taipei Veterans General Hospital ( Site 1002), Taipei, Not set
Ege Universitesi Tıp Fakultesi ( Site 1052), Izmir, Bornova
Baskent University Adana Dr. Turgut Noyan EAH ( Site 1057), Adana, Not set
Ankara UTF ( Site 1055), Ankara, Not set
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 1060), Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji EAH ( Site 1053), Ankara, Not set
Trakya Uni. Tip Fakultesi ( Site 1063), Edirne, Not set
Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 1058), Istanbul, Not set
Medipol Hastanesi ( Site 1066), Istanbul, Not set
Medeniyet Uni. Goztepe Egitim ve Arast. Hast. ( Site 1064), Istanbul, Not set
Medical Park Izmir Hospital ( Site 1051), Izmir, Not set
Kocaeli Universitesi Tip Fakultesi ( Site 1061), Kocaeli, Not set
Inonu Universitesi Tip Fakultesi ( Site 1059), Malatya, Not set
Birmingham Heartlands Hospital ( Site 1162), Birmingham, Not set
St James s University Hospital ( Site 1161), Leeds, Not set
North Middlesex Hospital ( Site 1151), London, Not set
Maidstone Hospital ( Site 1155), Maidstone, Not set
Mount Vernon Cancer Centre ( Site 1156), Northwood, Not set
Conditions: Small Cell Lung Cancer (SCLC)
PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients
Terminated
The primary purpose of this study is to establish the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) of PDR001 when administered in combination with platinum-doublet chemotherapy and other immunooncology agent(s) in treatment naive patients with PD-L1 unselected, advanced NSCLC, and to estimate the preliminary anti-tumor activity in this patient population.
The primary purpose of this study is to establish the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) of PDR001 when administered in combination with platinum-doublet chemotherapy and other immunooncology agent(s) in treatment naive patients with PD-L1 unselected, advanced NSCLC, and to estimate the preliminary anti-tumor activity in this patient population. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2022
Locations: Highlands Oncology Group, Fayetteville, Arkansas +22 locations
Highlands Oncology Group, Fayetteville, Arkansas
UCLA Santa Monica Hematology / Oncology SC-2, Santa Monica, California
Stanford Cancer Center SC, Stanford, California
Henry Ford Health System SC, Detroit, Michigan
Washington University School of Medicine SC, Saint Louis, Missouri
Novartis Investigative Site, Leuven, Not set
Novartis Investigative Site, Roeselare, Not set
Novartis Investigative Site, Toronto, Ontario
Novartis Investigative Site, Praha 4, Not set
Novartis Investigative Site, Lyon Cedex, Not set
Novartis Investigative Site, Marseille Cedex 05, Not set
Novartis Investigative Site, Gottingen, Not set
Novartis Investigative Site, Koeln, Not set
Novartis Investigative Site, Pokfulam, Not set
Novartis Investigative Site, Meldola, FC
Novartis Investigative Site, Rozzano, MI
Novartis Investigative Site, Aviano, PN
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Amsterdam, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Madrid, Not set
Conditions: Non-small Cell Lung Cancer
Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer
Completed
The purpose of this clinical trial is to find out whether or not the combination of NOV-002 with chemotherapy (paclitaxel and carboplatin) is better at improving overall survival time when compared to chemotherapy alone in people with non-small cell lung cancer (NSCLC).
Earlier clinical trials in NSCLC showed that patients treated with NOV-002 in combination with chemotherapy had a better response (their tumors got smaller in one United States Phase 1/2 trial) than patients who received chemoth... Read More
The purpose of this clinical trial is to find out whether or not the combination of NOV-002 with chemotherapy (paclitaxel and carboplatin) is better at improving overall survival time when compared to chemotherapy alone in people with non-small cell lung cancer (NSCLC).
Earlier clinical trials in NSCLC showed that patients treated with NOV-002 in combination with chemotherapy had a better response (their tumors got smaller in one United States Phase 1/2 trial) than patients who received chemotherapy alone; and in two Phase 2 trials done in Russian patients, at the end of one year, patients treated with NOV-002 with chemotherapy had a better survival rate than patients who did not receive NOV-002 with their chemotherapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/19/2022
Locations: Northwest Alabama Cancer Center, Muscle Shoals, Alabama +74 locations
Northwest Alabama Cancer Center, Muscle Shoals, Alabama
Sharp Memorial Hospital, San Diego, California
University of Chicago Medical Center, Chicago, Illinois
Northern Indiana Cancer Research Consortium, South Bend, Indiana
St. Agnes Hospital, Baltimore, Maryland
Massachusetts General Hospital, Boston, Massachusetts
University of Minnesota Medical Center, Fairview, Minneapolis, Minnesota
Park Nicollet Clinic - Cancer Center St. Louis Park, Saint Louis Park, Minnesota
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Cleveland Clinic Foundation Taussig Cancer Center, Cleveland, Ohio
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
South Texas Institute of Cancer, Corpus Christi, Texas
William Osler Health Center, Brampton, Ontario
Humber River Regional Hospital, Weston, Ontario
Jewish General Hospital, Montreal, Quebec
Laval Hospital, Sainte-Foy, Quebec
Barzilai Medical Center, Ashkelon, Not set
Lin Clinic, Haifa, Not set
Meir Medical Center, Kfar-Saba, Not set
Institute of Oncology, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Assaf Harofeh Hospital, Zerifin, Not set
Azienda Ospedaliera Treviglio Caravaggio, Bergamo, Not set
Azienda Ospedaliera Careggi, Firenze, Not set
Sondrio Hospital, Sondrio, Not set
Oddzial Pulmonologiczny z Pododdzialem Chemioterapii, Bystra, Not set
Samodzielny Publiczny Szpital Kliniczny N°.1, Gdansk, Not set
Oddzial Chemioterapii Pomorskie Centrum Onkologii,, Gdynia, Not set
Katedra Onkologii Akademii Medycznej w Lodzi, Lodz, Not set
Oddzial Chemioterapii Zaklad Opieki Zdrowotnej MSWiA, Olsztyn, Not set
Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy Oddzial III, Otwock, Not set
Wielkopolskie Centrum Chorob, Poznan, Not set
Oddzial Gruzlicy I Chorob Pluc I P, Prabuty, Not set
Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie w Warszawie, Warsaw, Not set
Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie, Warszawa, Not set
S.C. Oncomed SRL, Timisoara, Timis County
Institute of Oncology, Department of Medical Oncology II, Bucharest, Not set
Institute of Oncology Cluj-Napoca, Cluj-Napoca, Not set
Institute of Oncology, Cluj-Napoca, Cluj-Napoca, Not set
Craiova Emergency Clinical County Hospital, Craiova, Not set
Arkhangelsk Regional Clinical Oncology Center, Arkhangelsk, Not set
Chelyabinsk Regional Oncology Center, Chemotherapy Department, Chelyabinsk, Not set
Clinical Oncology Center, Chemotherapy Department, Kazan, Not set
Omsk Regional Clinical Oncology Center, Omsk, Not set
Orenburg Regional Clinical Oncology Center, Orenburg, Not set
Stavropol Regional Clinical Oncology Center, Pyatigorsk, Not set
Oncology Center, Hematology Department, Sochi, Not set
Leningrad Regional Clinical Hospital, Department of Thoracic Surgery, St. Petersburg, Not set
City General Hospital #2, City Center of Intensive Pulmonology and Thoracic Surgery, St. Petersburg, Not set
St. Petersburg Pavlov State Medical University under the Federal Agency for Healthcare and Social Development, St. Petersburg, Not set
City Clinical Oncology Center, Thoracic Department, St. Petersburg, Not set
Stavropol Regional Clinical Oncology Center, Chemotherapy Department, Stavropol, Not set
Tambov Regional Oncology Center, Chemotherapy Department, Tambov, Not set
Kazan Oncology Center, Tatarstan, Not set
Voronezh Regional Clinical Oncology Center, Voronezh, Not set
Clinical Hospital Center Bezanijska kosa, Belgrade, Not set
Clinical Center Nis, Clinic for Lung Diseases "Knez Selo", Nis, Not set
Institute of Lung Diseases Sremka Kamenica, Sremska Kamenica, Not set
Hospital Clinic i Provincial de Barcelona, Barcelona, Not set
Hospital Mutua de Terrassa, Terrassa, Not set
Kantonales Spital Sursee-Wolhusen, Sursee, Not set
Cherkasy Regional Oncology Center, Cherkassy, Not set
Public Treatment and Prophylaxis Institution: Chernihiv Regional Oncology Center, Chernihiv, Not set
City General Hospital #4, Dnipropetrovsk, Not set
Regional Oncological Center, Ivano-Frankivsk, Not set
S.P. Grigoryev Institute of Medical Radiology, Kharkiv, Not set
Oncology Institute under the Ukrainian Academy of Medical Sciences, Kyiv, Not set
Crimean Republican Clinical Oncology Center, Simferopol, Not set
Zakarpatsky Regional Oncological Clinical Center, Uzhorod, Not set
Anchor Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland
Ninewells Hospital and Medical School Department of Cancer Medicine, Dundee, Scotland
St. Luke's Cancer Centre, Guildford, Surrey
Oncology Research, Nottingham City Hospital, Nottingham, Not set
Dorset Cancer Centre, Poole Hospital, Poole, Not set
Yeovil District Hospital NHS Foundation Trust, Higher Kingston, Somerset, Not set
Conditions: Non Small Cell Lung Cancer
Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)
Terminated
The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not eligible to receive cisplatin, are harboring FGFR3 mutation or rearrangement, and who have not received prior treatment.
The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not eligible to receive cisplatin, are harboring FGFR3 mutation or rearrangement, and who have not received prior treatment. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/24/2022
Locations: Marin Cancer Care, Greenbrae, California +78 locations
Marin Cancer Care, Greenbrae, California
Christiana Care Helen F. Graham Cancer Center, Newark, Delaware
Cotton-O'Neil Clinical Research Center, Hematology & Oncology, Marietta, Georgia
Simmons Cancer Institute At Siu, Springfield, Illinois
The University of Kansas Cancer Center, Westwood, Kansas
Smhc Cancer Blood Disorders, Biddeford, Maine
Summit Medical Group, Florham Park, New Jersey
Mount Sinai School of Medicine, New York, New York
Oregon Health & Science University, Portland, Oregon
Charleston Hematology Oncology Associates, Charleston, South Carolina
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
The Center For Cancer and Blood Disorders, Fort Worth, Texas
Onc Consultants Pharmacy 2, Houston, Texas
Wilhelminenspital, Vienna, Not set
Grand Hopital de Charleroi, Charleroi, Not set
Universitaire Ziekenhuis Leuven - Gasthuisberg, Leuven, Not set
Moncton Hospital - Horizon Health Network, Moncton, New Brunswick
Helsinki University Meilahti Tower Hospital, Helsinki, Not set
Fonk Onkologian Klinikka, Tampere, Not set
Turku University Hospital, Sct Unit, Turku, Not set
Centre Hospitalier Universitaire de Besancon, Besancon, Not set
Groupe Hospitalier Pellegrin Tripode, Bordeaux, Not set
Polyclinique de Blois, La Chaussee-saint-victor, Not set
Chu Nimes, Nimes, Not set
Groupe Hospitalier Pitie-Salpetriere, Paris, Not set
Hopital Cochin Cancerologie, Paris, Not set
Hopital Europeen Georges Pompidou (Hegp), Paris, Not set
Centre Hospitalier Universitaire de Poitiers, Poitiers, Not set
Chu de Strasbourg Hopitaux Universitaires Service D Hematologie, Strasbourg, Not set
Institut Claudius Regaud Oncopole Toulouse, Toulouse, Not set
Kliniken Maria Hilf, Moenchengladbach, Not set
University Hospital Waterford, Waterford, Not set
Iov - Istituto Oncologico Veneto Irccs, Bari, Not set
Istituto Tumori Giovanni Paolo Ii Irccs Ospedale Oncologico Bari, Bari, Not set
L AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA POLICLINICO S. ORSOLA � MALPIGHI, Bologna, Not set
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori, Meldola, Not set
Fondazione Irccs Istituto Nazionale Dei Tumori, Milano, Not set
Ieo Istituto Europeo Di Oncologia Irccs, Milano, Not set
Fondazione Irccs Ca Granda Ospedale Maggiore, Milan, Not set
Istituto Nazionale Tumori Fondazione Irccs G. Pascale, Napoli, Not set
UNIVERSIT� CAMPUS BIO-MEDICO DI ROMA, Roma, Not set
Irrcs Instituto Clinico Humanitas, Rozzano, Not set
Azosp S.Maria Sc Oncologia, Terni, Not set
Chiba University Hospital, Chiba, Not set
Chiba Cancer Center, Chiba, Not set
National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set
Saitama Medical University International Medical Center, Hidaka-shi, Not set
Hirosaki University Hospital, Hirosaki-shi, Not set
Hakodate Goryokaku Hospital, Hokkaido, Not set
Sapporo Medical University Hospital, Hokkaido, Not set
Nihon University Itabashi Hospital, Itabashi-ku, Not set
Nara Medical University Hospital, Kashihara-shi, Not set
St. Marianna University School of Medicine Hospital, Kawasaki-shi, Not set
Kagawa University Hospital, Kita-gun, Not set
Nho Shikoku Cancer Center, Matsuyama, Not set
Toranomon Hospital, Minato-ku, Not set
Osaka International Cancer Institute, Osaka-shi, Not set
Saitama Medical Center Jichi Medical University, Saitama-shi, Not set
Tohoku University Hospital, Sendai-shi, Not set
Jichi Medical University Hospital, Shimotsuke-shi, Not set
Keio University Hospital, Shinjuku-ku, Not set
Osaka University Hospital, Suita-shi, Not set
National Cancer Center Hospital, Tokyo, Not set
Toyama University Hospital, Toyama, Not set
Olsztynski Osrodek Onkologiczny Kopernik, Olsztyn, Not set
Champalimaud Foundation - Champalimaud Centre For the Unknown (Champalimaud Cancer Center), Lisboa, Not set
Spitalul Clinic Judetean de Urgenta 'Sf Apostol Andrei' Constanta, Constanta, Not set
Fakultna Nemocnica S Poliklinikou Zilina, Zilina, Not set
Hospital Clinic I Provincial, Barcelona, Not set
Ico Institut Catala D Oncologia, Barcelona, Not set
Ico Girona, Girona, Not set
Hospital Clinico San Carlos, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario de La Paz, Madrid, Not set
Hospital Universitario Hm Sanchinarro, Madrid, Not set
Hospital Puerta de Hierro, Majadahonda, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
Barts Health Nhs Trust - St Bartholomews Hospital, London, Not set
Conditions: Metastatic Urothelial Carcinoma, Unresectable Urothelial Carcinoma
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