Cyclophosphamide Treatment Options in Canada

A collection of 300 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the Canada . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

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Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer

NCT06048705

Terminated

The primary purpose of this sub study is to assess the safety, tolerability and determine recommended Phase 2 dose (RP2D) of GSK3901961 in HLA A\*02:01, HLA-A\*02:05 and/or HLA A\*02:06 positive participants with New York esophageal squamous cell carcinoma (NY ESO 1) and/or Cancer testis antigen 2 (LAGE 1a) positive previously treated metastatic Non-Small Cell Lung Cancer (NSCLC) and previously treated, advanced (metastatic or unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma SS/MRCL... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/08/2024

Locations: GSK Investigational Site, New Haven, Connecticut +20 locations

Conditions: Neoplasms

Learn More ›

Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

NCT05943990

Terminated

To assess the safety, tolerability and determine recommended phase 2 dose (RP2D) of GSK3845097 in HLA-A\*02:01, HLA-A\*02:05 and/or HLA-A\*02:06 positive participants with New York esophageal squamous cell carcinoma (NY-ESO)-1 and/or Cancer testis antigen 2 (LAGE-1a) positive, previously treated, advanced (metastatic or unresectable) Synovial Sarcoma (SS) and Myxoid/Round Cell Liposarcoma (MRCLS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/08/2024

Locations: GSK Investigational Site, New Haven, Connecticut +20 locations

Conditions: Neoplasms

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Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors

NCT04526509

Terminated

This trial will evaluate the safety and efficacy of first time in human engineered T-cell therapies, in participants with advanced tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/08/2024

Locations: GSK Investigational Site, Jacksonville, Florida +16 locations

Conditions: Neoplasms

Learn More ›

Phase 3 Study of Zandelisib (ME-401) in Combination With Rituximab in Patients With iNHL - (COASTAL)

NCT04745832

Terminated

This is a Phase 3 study of the PI3Kδ inhibitor Zandelisib (ME-401) in combination with rituximab, in comparison to standard immunochemotherapy (Rituximab-Bendamustine or Rituximab-CHOP) in subjects with relapsed or refractory FL and MZL.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

10/31/2024

Locations: The Oncology Institute of Hope and Innovation, Tucson, Arizona +140 locations

The Oncology Institute of Hope and Innovation, Tucson, Arizona

Orange Coast Memorial Medical Center, Fountain Valley, California

Long Beach Memorial Medical Center, Long Beach, California

The Oncology Institute of Hope and Innovation, Riverside, California

BRCR Medical Center Inc, Hollywood, Florida

Henry Ford Hospital, Detroit, Michigan

Revive Research Institute, Farmington Hills, Michigan

Revive Research Institute, Sterling Heights, Michigan

Mercy Clinic Cancer & Hematology - Chub O'Reilly Cancer Center, Springfield, Missouri

Inspira Medical Center Mullica Hill, Mullica Hill, New Jersey

MetroHealth Medical Center, Cleveland, Ohio

Alpha Research Institute, LLC, Baytown, Texas

Valley Cancer Associates, Harlingen, Texas

Community Cancer Trials of Utah, Ogden, Utah

Canberra Hospital, Garran, Not set

The Perth Blood Institute (PBI), West Perth, Not set

Westmead Hospital, Westmead, Not set

AZ Sint-Jan Burgge-Oostende AV, Brugge, Not set

UZ Brussel, Brussel, Not set

Universitair Ziekenhuis Antwerpen, Edegem, Not set

Center Hospitalier de Jolimont, Haine-Saint-Paul, Not set

UZ Leuven Campus Gasthuisberg, Leuven, Not set

Eastern Regional Health Authority, Saint John's, Newfoundland and Labrador

Centre intégré universitaire de santé et de services sociaux de l'Estrie, Sherbrooke, Quebec

McGill University Health Centre, Québec, Not set

CHU Estaing. Service d'hématologie clinique et de thérapie cellulaire adulte,, Clermont-Ferrand, Not set

Centre Hospitalier De Dunkerque - Service d'hématologie, Le Mans, Not set

Centre Hospitalier du Mans, Le Mans, Not set

Centre Leon Berard, Lyon, Not set

Hôpital Saint-Louis, Paris, Not set

CHU de Bordeaux - Maladies Du Sang, Centre François Magendie, Pessac, Not set

Centre Henri Becquerel, Service d'Hematologie, Rouen, Not set

CHU de Tours, Hôpital Bretonneau Centre, Tours Cedex 1, Not set

Institut De Cancerologie Gustave Roussy, Villejuif, Not set

LTD Israeli-Georgian Medical Research Clinic "Helsicore", Tbilisi, Not set

M. Zodelava Hematology Center, Tbilisi, Not set

J.S.C. K. Eristavi National Center of Experimental and Clinic, Tbilisi, Not set

LTD "Medinvest" Institute of Hematology and Transfusiology, Tbilisi, Not set

General Hospital of Athens "Laiko", Department of Haematology and Bone Marrow Transplantation, Athens, Not set

University General Hospital of Ioannina, Department of Haematology, Ioánnina, Not set

University General Hospital of Patras "Panagia H. Voitheia", Patras, Not set

General Hospital of Thessaloniki "G. Papanikolaou", Thessaloníki, Not set

Országos Onkológiai Intézet Gyógyszerterápiás Központ Hematológia és Lymphoma Osztály, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Belgyogyaszati Klinika, Debrecen, Not set

Szabolcs-Szatmar-Bereg Megyei Korhazak es Egyetemi Oktatokorhaz,, Nyiregyhaza, Not set

SOC Oncologia Medica e dei Tumori Immunocorrelati, Aviano, Not set

UO di Ematologia "L.e A.Seragnoli" Policlinico Sant'Orsola Malpighi, Bologna, Not set

U.O. Ematologia, Azienda Ospedaliera S. Croce e Carle, Cuneo, Not set

U.O. Ematologia - Azienda Ospedaliero-Universitaria Careggi, Firenze, Not set

U.O. Clinica Ematologica, Genova, Not set

SC Oncologia Medica, Meldola, Not set

UOC Ematologia, Presidio Ospedaliero Papardo, Messina, Not set

UO Ematologia 1 Azienda ULSS 3 Serenissima, Distertto del veneziano - Ospedale dell'Angelo di Mestre, Mestre, Not set

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milano, Not set

Dipartimento di Oncoematologia, Unità Linfomi, Ospedale, Milano, Not set

Divisione Oncoematologia, Istituto Europeo di Oncologia, Milano, Not set

Azienda Ospedaliera Ospedali Riuniti Via Sofia, Palermo, Not set

UO Ematologia, Ospedale Civile S.Maria delle Croci, Ravenna, Not set

UO Ematologia, Ospedale Infermi di Rimini AUSL Romagna, Rimini, Not set

Istituti Fisioterapici Ospitalieri, Roma, Not set

S.C. Oncoematologia Azienda Ospedaliera Santa Maria, Terni, Not set

National Hospital Organization Nagoya Medical Center, Naka-ku, Aichi

National Hospital Organization Shikoku Cancer Center, Matsuyama-Shi, Ehime

National Hospital Organization Kyushu Cancer Center, Minami, Fukuoka

Gunma University Hospital, Maebashi, Gunma

Kobe City Medical Center General Hospital, Kobe, Hyogo

Kagoshima University Hospital, Sakuragaoka, Kagoshima-Shi, Kagoshima

University Hospital Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto

Kindai University Hospital, Osakasayama-shi, Osaka

Anjo Kosei Hospital, Aichi, Not set

Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Aichi, Not set

Aomori Prefectural Central Hospital, Aomori, Not set

Chiba Cancer Center, Chiba, Not set

Kyushu University Hospital, Fukuoka, Not set

Chugoku Central Hospital, Hiroshima, Not set

Hokkaido University Hospital, Hokkaido, Not set

National Hospital Organization Kumamoto Medical Center, Kumamoto, Not set

Kyoto University Hospital, Kyoto, Not set

National University Corporation Tohoku University Hospital, Miyagi, Not set

Aichi Cancer Center Hospital, Nagoya, Not set

Okayama University Hospital, Okayama, Not set

Osaka International Cancer Institute, Osaka, Not set

Osaka University Hospital, Osaka, Not set

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Not set

The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Tokyo, Not set

Keio University Hospital, Tokyo, Not set

Inje University Busan Paik Hospital, Busan, Not set

Dong-A university Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Kyungpook National University Hospital, Daegu, Not set

Chonnam National University Hwasun Hospital, Jeollyang, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea, Seoul, Not set

Ewka Womans University Mokdong Hospital, Seoul, Not set

Ulsan University Hospital, Ulsan, Not set

Albert Schweizer Ziekenhuis, Hematology Department, Dordrecht, Not set

Spaarne Gasthuis, Oncology Department, Hoofddorp, Not set

Canterbury District Health Board, Haematology Department, Christchurch, Not set

Dunedin Hospital, Southern Blood and Cancer Service, Dunedin, Not set

Klinika Hematologii, Szpital Uniwersytecki, Bydgoszcz, Not set

Pratia MCM Krakow, Kraków, Not set

ARS Medical - Szpital, Oddzial hematologiczny, Piła, Not set

Centrum Medyczne Pratia Poznan, Skorzewo, Not set

University Clinical Center of Serbia, Clinic for Hematology, Belgrade, Not set

Zvezdara University Medical Center, Clinical department for Hematology and Oncology, Belgrade, Not set

Clinical Hospital Center "Zemun", Clinic for Internal Medicine, Department for Hematology, Belgrade, Not set

Oncology Institute of Vojvodina, Clinic for Internal Oncology, Kamenica, Not set

University Clinical Center Kragujevac, Clinic for Hematology, Kragujevac, Not set

Clinical Center of Vojvodina, Clinic for Hematology, Novi Sad, Not set

Hospital Universitario Quironsalud, Alcorcón, Madrid

Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Oncology, Barcelona, Not set

Hospital Universitario Mútua Terrassa, Barcelona, Not set

Institut Catalá d'Oncologia, Hospital Duran i Reynals, Barcelona, Not set

Hospital Universitario Ramón y Cajal, Madrid, Not set

Complejo Hospitalario de Navarra, Navarro, Not set

Hospital Universitario de Canarias, Santa Cruz De Tenerife, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Chi Mei Hospital, Tainan City, Not set

National Cheng Kung University Hospital, Tainan, Not set

Gazi University Health Research and Application Hospital, Hematology Department, Ankara, Not set

Istanbul University Istanbul Medical Faculty, Hematology Department, Istanbul, Not set

Erciyes University Medical Faculty, Department of Hematology, Kayseri, Not set

Ondokuz Mayis University Medical Faculty, Hematology Department, Samsun, Not set

Namik Kemal University Hospital, Tekirdağ, Not set

Karadeniz Technical University Medical Faculty Department of Hematology, Trabzon, Not set

North Wales Cancer Treatment Centre, Bodelwyddan, Denbighshire

Royal Cornwall Hospital, Cornwell, Not set

Department of Haematology St. George's University of London, London, Not set

The Royal Marsden NHS Foundation Trust - Royal Marsden Hospital, London, Not set

Imperial College Healthcare NHS Trust Hammersmith Hospital, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Genesis Care Oxford, Oxford, Not set

University Hospitals Plymouth NHS Trust, Derriford Hopital, Plymouth, Not set

The Royal Marsden NHS Foundation Trust - Royal Marsden Hospital, Surrey Quays, Not set

Conditions: Follicular Lymphoma (FL), Non Hodgkin Lymphoma, Marginal Zone Lymphoma

Learn More ›

A Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel (KTE-X19) in Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ZUMA-3)

NCT02614066

Completed

The primary objectives of this study are to determine the safety and efficacy of brexucabtagene autoleucel (KTE-X19) in adult participants with relapsed/refractory (r/r) B-precursor acute lymphoblastic leukemia (ALL).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

10/30/2024

Locations: UC San Diego-Moores Cancer Center, La Jolla, California +32 locations

UC San Diego-Moores Cancer Center, La Jolla, California

University of California Los Angeles (UCLA), Los Angeles, California

University of California Irvine Medical Center, Orange, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

University of California San Francisco, San Francisco, California

H Lee Moffitt Cancer Center, Tampa, Florida

Emory University, Atlanta, Georgia

Loyola University, Chicago, Illinois

University of Chicago, Chicago, Illinois

University of MD Greenbaum Comprehensive Cancer Center, Baltimore, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Mount Sinai Tisch Cancer Institute, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

University of Rochester, New York, New York

Sarah Cannon, Nashville, Tennessee

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee

Baylor Charles A. Sammons Cancer Center, Dallas, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Swedish Cancer Institute, Seattle, Washington

Seattle Cancer Center, Seattle, Washington

University Health Network - Princess Margaret, Toronto, Ontario

Institut Paoli Calmettes, Marseille, Not set

Hopital Saint Louis, Paris, Not set

Hopital Haut-Leveque, Pessac, Not set

Hopital Pontchaillou - CHU de Rennes - Service d'Hematologie, Rennes, Not set

Universitatsklinikum Frankfurt, Frankfurt, Not set

Klinikum der Universitat Munchen, München, Not set

Universitaetsklinikum Wuerzburg, Würzburg, Not set

Amsterdam UMC, Amsterdam, Not set

Erasmus MC, Rotterdam, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

Learn More ›

Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma

NCT01096368

Active Not Recruiting

The primary aim of this randomized phase III trial was to study whether the addition of maintenance chemotherapy delivered after surgical resection and focal radiation would be better than surgery and focal radiation alone. The trial also studied if patients who received induction chemotherapy and then either achieved a complete response or went on to have a complete resection would also benefit from maintenance chemotherapy. Children ages 1-21 years with newly diagnosed intracranial ependymoma... Read More

Gender:

ALL

Ages:

Between 12 months and 21 years

Trial Updated:

10/16/2024

Locations: Children's Hospital of Alabama, Birmingham, Alabama +208 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Banner Children's at Desert, Mesa, Arizona

Phoenix Childrens Hospital, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Lee Memorial Health System, Fort Myers, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Tulane University Health Sciences Center, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Ascension Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Columbia Regional, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Winthrop Hospital, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

John Hunter Children's Hospital, Hunter Regional Mail Centre, New South Wales

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Royal Brisbane and Women's Hospital, Herston, Queensland

Royal Children's Hospital-Brisbane, Herston, Queensland

Queensland Children's Hospital, South Brisbane, Queensland

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Monash Medical Center-Clayton Campus, Clayton, Victoria

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Perth Children's Hospital, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

Conditions: Anaplastic Ependymoma, Brain Ependymoma, Cellular Ependymoma, Clear Cell Ependymoma, Ependymoma, Papillary Ependymoma

Learn More ›

A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer

NCT03726879

Completed

This study (also known as IMpassion050) will evaluate the efficacy and safety of atezolizumab compared with placebo when given in combination with neoadjuvant dose-dense anthracycline (doxorubicin) + cyclophosphamide followed by paclitaxel + trastuzumab + pertuzumab (ddAC-PacHP) in patients with early HER2-positive breast cancer (T2-4, N1-3, M0).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

10/11/2024

Locations: HCA Midwest Division, Kansas City, Missouri +75 locations

HCA Midwest Division, Kansas City, Missouri

New York University Medical Center PRIME; NYU Langone Medical Center, New York, New York

Tennessee Oncology - Nashville, Nashville, Tennessee

Hospital Sao Rafael - HSR, Salvador, BA

Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO

Hospital Nossa Senhora da Conceicao, Porto Alegre, RS

Hospital Sao Lucas - PUCRS, Porto Alegre, RS

Hospital Perola Byington, Sao Paulo, SP

Tom Baker Cancer Centre-Calgary, Calgary, Alberta

BCCA-Vancouver Cancer Centre, Vancouver, British Columbia

Jewish General Hospital, Montreal, Quebec

Hopital du Saint Sacrement, Quebec City, Quebec

Masarykuv onkologicky ustav, Brno, Not set

Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set

Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum, Essen, Not set

Praxis für Interdisziplinäre Onkologie und Hämatologie GbR, Freiburg, Not set

Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem, Hamburg, Not set

Sankt Elisabeth Krankenhaus; Gynaekology, Leipzig, Not set

Rotkreuzklinikum München; Frauenklinik, Muenchen, Not set

Universitätsklinikum Münster; Klinik für Frauenheilkunde und Geburtshilfe, Münster, Not set

St. Vincenz-Krankenhaus Paderborn; Haus 3 Frauenklinik, Paderborn, Not set

Universitätsfrauenklinik Ulm; Abteilung Gynäkologie, Ulm, Not set

Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica, Napoli, Campania

Università degli Studi Federico II; Clinica di Oncologia Medica, Napoli, Campania

Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica, Aviano, Friuli-Venezia Giulia

Policlinico Universitario Agostino Gemelli, Roma, Lazio

ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica, Brescia, Lombardia

ASST DI MONZA; Oncologia Medica, Monza, Lombardia

Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia, Rozzano, Lombardia

Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico, Candiolo, Piemonte

IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto

National Hospital Organization Shikoku Cancer Center, Ehime, Not set

Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Not set

Hiroshima University Hospital, Hiroshima, Not set

National Hospital Organization Hokkaido Cancer Center, Hokkaido, Not set

Hyogo Cancer Center, Hyogo, Not set

Kanagawa Cancer Center, Kanagawa, Not set

Tokai University Hospital, Kanagawa, Not set

Kumamoto Shinto General Hospital, Kumamoto, Not set

Fukushima Medical University Hospital, Miyagi, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Saitama Medical University International Medical Center, Saitama, Not set

Toranomon Hospital, Tokyo, Not set

Showa University Hospital, Tokyo, Not set

Gachon University Gil Medical Center, Incheon, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Samsung Medical Centre; Oncology, Seoul, Not set

Instytut "Centrum Zdrowia Matki Polki"; Klinika Onkologii, ?ód?, Not set

Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; Centr.Diagn.i Lecz.Chor.Piersi, Gliwice, Not set

Regionalny Szpital Specjalistyczny im. W. Bieganskiego; Oddzial Onkologii Klinicznej, Grudzi?dz, Not set

Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii, Kraków, Not set

Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad; Klinika Nowtw.Piersi i Chir.Rekonstr, Warszawa, Not set

FSBI National Medical Research Radiological Center; A. TSYB MEDICAL RADIOLOGICAL RESEARCH CENTER, Obninsk, Kaluga

City Clinical Oncology Hospital, Moscow, Moskovskaja Oblast

SBIH "Moscow Clinical Scientific and Practical Center named after A.S. Loginov of DHM", Moskva, Moskovskaja Oblast

Blokhin Cancer Research Center; Combined Treatment, Moskva, Moskovskaja Oblast

Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic, Kazan, Tatarstan

Petrov Research Inst. of Oncology, Sankt Petersburg, Not set

Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia, Badalona, Barcelona

Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona

Hospital Universitario Virgen de La Arrixaca; Servicio De Oncologia, El Palmar, Murcia

Clinica Universitaria de Navarra; Servicio de Oncologia, Pamplona, Navarra

Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set

Complejo Asistencial Universitario De Burgos; Servicio de Oncologia, Burgos, Not set

Hospital Clinico de Granada; Servicio de Oncologia, Granada, Not set

Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia, Jaen, Not set

Hospital Universitari Arnau de Vilanova de Lleida; Servicio de Oncologia, Lerida, Not set

Clinica Universidad de Navarra Madrid; Servicio de Oncología, Madrid, Not set

Centro Integral Oncologico Clara Campal; Servicio de Oncología, Madrid, Not set

Hospital Universitario Virgen Macarena; Servicio de Oncologia, Sevilla, Not set

Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, Not set

China Medical University Hospital; Surgery, Taichung, Not set

Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology, Taipei City, Not set

Mackay Memorial Hospital; Dept of Surgery, Taipei, Not set

Chang Gung Medical Foundation - Linkou; Dept of Surgery, Taoyuan, Not set

Conditions: Breast Cancer

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A Study of Zilovertamab Vedotin (MK-2140) in Combination With Cyclophosphamide, Doxorubicin, and Prednisone Plus Rituximab or Rituximab Biosimilar (Truxima) (R-CHP) in Participants With Diffuse Large B-Cell Lymphoma (DLBCL) (MK-2140-007)

NCT05406401

Active Not Recruiting

This study consists of a dose escalation/confirmation phase and an efficacy expansion phase. The dose escalation/confirmation phase is to determine the safety and tolerability and establish a preliminary recommended Phase 2 dose (RP2D) of zilovertamab vedotin when administered in combination with R-CHP in participants with DLBCL who have received no prior treatment for their disease. The efficacy expansion phase is to determine the efficacy of the RP2D of zilovertamab vedotin when administered i... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

10/10/2024

Locations: BC Cancer Victoria-Clinical Trials Unit ( Site 0105), Victoria, British Columbia +21 locations

BC Cancer Victoria-Clinical Trials Unit ( Site 0105), Victoria, British Columbia

William Osler Health System ( Site 0106), Toronto, Ontario

Hopital du Sacre-Coeur de Montreal ( Site 0108), Montreal, Quebec

Hadassah Medical Center ( Site 0401), Jerusalem, Not set

Sheba Medical Center-Hemato Oncology ( Site 0400), Ramat Gan, Not set

Fondazione Policlinico Universitario Agostino Gemelli-ISTITUTO DI EMATOLOGIA ( Site 0306), Roma, Lazio

Ospedale San Raffaele-Unità Linfomi ( Site 0305), Milano, Lombardia

Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO-EMATOLOGIA I ( Site 0307), Palermo, Sicilia

Azienda Ospedaliera Universitaria Careggi-SOD Ematologia ( Site 0308), Firenze, Toscana

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare -Azienda Ospedaliera Nazionale SS. Ant, Alessandria, Not set

Seoul National University Hospital ( Site 0201), Seoul, Not set

Samsung Medical Center ( Site 0200), Seoul, Not set

Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumat-Oddiał Hematologii Ogólnej ( Site 0503), Łódź, Lodzkie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Kilinka Onkologii I Hematologii ( Site, Warszawa, Mazowieckie

Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 0504), Gdańsk, Pomorskie

Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 0505), Gliwice, Slaskie

HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Hematology ( Site 0704), Sevilla, Andalucia

Instituto Catalan de Oncologia - Hospital Duran i Reynals-Haematology Department ( Site 0703), L'Hospitalet Del Llobregat, Barcelona

Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 0700), Madrid, Not set

Mega Medipol-Hematology ( Site 0808), Stanbul, Istanbul

Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 0801), Ankara, Not set

Trakya University ( Site 0805), Edirne, Not set

Conditions: Lymphoma, Large B-Cell, Diffuse (DLBCL)

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Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors

NCT02869217

Active Not Recruiting

The target populations for this phase I study with TBI-1301 are patients with advanced solid tumors. Patients' tumors will be required to express NY-ESO-1, which include but is not limited to ovarian cancer, synovial sarcoma, esophageal cancer, lung cancer, bladder cancer, liver cancer, and malignant melanoma. Patients must be positive for HLA-A\*02:01 or HLA-A\*02:06 and the patient's tumor tissue must be positive for NY-ESO-1 antigen expression. The study will take the subject's T cells, which... Read More

Gender:

ALL

Ages:

16 years and above

Trial Updated:

10/09/2024

Locations: Princess Margaret Cancer Centre, Toronto, Ontario

Conditions: NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients, Synovial Sarcoma, Melanoma, Esophageal Cancer, Ovarian Cancer, Lung Cancer, Bladder Cancer, Liver Cancer

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Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

NCT05993299

Active Not Recruiting

This trial will evaluate safety and efficacy of human engineered T-cell therapies, in participants with advanced tumors. This trial is a sub study of the Master study NCT03967223.

Gender:

ALL

Ages:

10 years and above

Trial Updated:

09/30/2024

Locations: City of Hope National Medical Center, Duarte, California +37 locations

City of Hope National Medical Center, Duarte, California

Stanford Hospital and Clinics, Stanford, California

Sarah Cannon Research Institute, Denver, Colorado

Mayo Clinic Jacksonville, Jacksonville, Florida

University of Chicago, Chicago, Illinois

University of Iowa College of Medicine, Iowa City, Iowa

Dana Farber Cancer Institute, Boston, Massachusetts

Massachusetts General Hospital, Boston, Massachusetts

University of Michigan Medical Center, Ann Arbor, Michigan

Minnesota Oncology Hematology, Minneapolis, Minnesota

Mayo Clinic Rochester, Rochester, Minnesota

Washington University, Saint Louis, Missouri

Memorial Sloan Kettering cancer center, New York, New York

Duke University Medical Center, Durham, North Carolina

Ohio State University-Columbus, Columbus, Ohio

Oregon Health and Science University, Portland, Oregon

University of Pittsburgh, Hillman Cancer centre, Pittsburgh, Pennsylvania

Tennessee Oncology, Nashville, Tennessee

University Of Texas Southwestern Medical Center, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

University of Utah, Salt Lake City, Utah

Virginia Commonwealth University, Richmond, Virginia

Fred Hutchinson Cancer Research Center, Seattle, Washington

Froedtert Hospital, Milwaukee, Wisconsin

CIUSSS de L'Est-De-Lile-De-Montreal, Montreal, Quebec

Princess Margaret Cancer Centre, Toronto, Not set

Centre Léon Bérard, Lyon cedex, Not set

CHU de Bordeaux GH Sud Hôpital Haut Lévêque, Pessac, Cedex, Not set

Fondazione IRCCS Instituto Nazionale Dei Tumori, Milano, Not set

Ircss Istituto Clinico Humanitas, Romano Di Lombardia, Not set

The Netherlands Cancer Institute, Amsterdam, Not set

Hospital Santa Creu Y Sant Pau, Barcelona, Not set

Ico Duran y Reynals l'Hospitalet de Llobrega, Hospitalet de Llobregat, Barcelona, Not set

Hospital Universitario Fundación Jiménez Díaz, Madrid, Not set

Hospital Virgen Del Rocio, Sevilla, Not set

Royal Marsden Hospital, London, Not set

University College Hospital-London, London, Not set

Christie Hospital NHS Foundation Trust, Manchester, Not set

Conditions: Neoplasms

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Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

NCT00336024

Active Not Recruiting

This randomized phase III trial is studying two different combination chemotherapy regimens to compare how well they work in treating young patients with newly diagnosed supratentorial primitive neuroectodermal tumors or high-risk medulloblastoma when given before additional intense chemotherapy followed by peripheral blood stem cell rescue. It is not yet known which combination chemotherapy regimen is more effective when given before a peripheral stem cell transplant in treating supratentorial... Read More

Gender:

ALL

Ages:

2 years and below

Trial Updated:

09/16/2024

Locations: Children's Hospital of Alabama, Birmingham, Alabama +144 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

Children's Hospital of Orange County, Orange, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Lee Memorial Health System, Fort Myers, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Tulane University School of Medicine, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Nevada Cancer Research Foundation NCORP, Las Vegas, Nevada

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

New York Medical College, Valhalla, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

East Tennessee Childrens Hospital, Knoxville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

San Jorge Children's Hospital, San Juan, Not set

Conditions: Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor, Anaplastic Medulloblastoma, Medulloblastoma, Supratentorial Embryonal Tumor, Not Otherwise Specified

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"Re-Stimulated" TILs and IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

NCT01883297

Active Not Recruiting

This is a phase I clinical study for patients with platinum-resistant high grade serous ovarian, fallopian tube, or primary peritoneal cancer, and the response to a combination of cyclophosphamide, autologous tumor-infiltrating lymphocytes (TILs), autologous dendritic cells (DCs), and OKT3 (anti-CD3 antibody), along with low-dose interleukin-2 (IL-2) therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/30/2024

Locations: Princess Margaret Cancer Centre, Toronto, Ontario

Conditions: Recurrent, Platinum-resistant, High Grade Serous Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer

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