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All Clinical Trials in Canada
A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
Recruiting
The main objective of this study is to evaluate treatment outcomes of tezepelumab among participants with physician-determined surgery-eligible CRSwNP, with or without asthma.
Study details include:
1. The study duration will be up to 40 weeks.
2. The treatment duration will be up to 24 weeks.
3. The visit frequency will be once every 4 weeks (Q4W).
The main objective of this study is to evaluate treatment outcomes of tezepelumab among participants with physician-determined surgery-eligible CRSwNP, with or without asthma.
Study details include:
1. The study duration will be up to 40 weeks.
2. The treatment duration will be up to 24 weeks.
3. The visit frequency will be once every 4 weeks (Q4W). Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
08/21/2025
Locations: Research Site, Newport Beach, California +43 locations
Research Site, Newport Beach, California
Research Site, Chicago, Illinois
Research Site, Chestnut Hill, Massachusetts
Research Site, Columbia, Missouri
Research Site, Plovdiv, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Hamilton, Ontario
Research Site, Quebec, Not set
Research Site, Quebec, Not set
Research Site, Le Kremlin-Bicêtre, Not set
Research Site, Lille, Not set
Research Site, Marseille, Not set
Research Site, Nantes Cedex 1, Not set
Research Site, Pierre Benite, Not set
Research Site, Poitiers, Not set
Research Site, Toulouse Cedex 9, Not set
Research Site, Düsseldorf, Not set
Research Site, Marburg, Not set
Research Site, Tubingen, Not set
Research Site, Villingen-Schwenningen, Not set
Research Site, Wiesbaden, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Nyiregyhaza, Not set
Research Site, Pécs, Not set
Research Site, Bologna, Not set
Research Site, Catania, Not set
Research Site, Firenze, Not set
Research Site, Napoli, Not set
Research Site, Padua, Not set
Research Site, Pisa, Not set
Research Site, Roma, Not set
Research Site, Rozzano, Not set
Research Site, Bialystok, Not set
Research Site, Bydgoszcz, Not set
Research Site, Zawadzkie, Not set
Research Site, Łódź, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Cadiz, Not set
Research Site, Madrid, Not set
Research Site, Salamanca, Not set
Research Site, Santiago de Compostela, Not set
Conditions: Chronic Rhinosinusitis With Nasal Polyps
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Recruiting
The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer.
The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: Southern Cancer Center, PC, Daphne, Alabama +190 locations
Southern Cancer Center, PC, Daphne, Alabama
Local Institution - 0283, Hot Springs, Arkansas
Florida Cancer Specialists - South, Fort Myers, Florida
Mid Florida Hematology and Oncology Center, Orange City, Florida
Florida Cancer Specialists - North, Saint Petersburg, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital, Marietta, Georgia
Illinois Cancer Care, Peoria, Illinois
Local Institution - 0037, Minneapolis, Minnesota
University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico
Duke Cancer Institute, Durham, North Carolina
Oncology Hematology Care, Cincinnati, Ohio
Local Institution - 0239, Cleveland, Ohio
Sanford Cancer Center, Sioux Falls, South Dakota
Local Institution - 0307, Knoxville, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
Texas Oncology - Central/South Texas, Austin, Texas
Texas Oncology - Northeast Texas, Tyler, Texas
Oncology & Hematology Associates of Southwest Virginia, Inc., Roanoke, Virginia
Swedish Cancer Institute - Edmonds, Edmonds, Washington
Swedish Medical Center, Seattle, Washington
Local Institution - 0007, Tacoma, Washington
Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Buenos Aires
Hospital Italiano de Buenos Aires, ABB, Ciudad Autónoma De Buenos Aires
Local Institution - 0100, Buenos Aires, Ciudad Autónoma De Buenos Aires
Clinica Adventista Belgrano, Caba, Ciudad Autónoma De Buenos Aires
Instituto Médico Río Cuarto, Río Cuarto, Córdoba
GenesisCare - Campbelltown, Campbelltown, New South Wales
Nepean Hospital, Penrith, New South Wales
Gallipoli Medical Research Ltd, Brisbane, Queensland
Grampians Health, Ballarat Central, Victoria
St. John of God Murdoch Hospital, Murdoch, Western Australia
Klinikum Wels-Grieskirchen GmbH, Wels, Oberösterreich
Medizinische Universität Graz, Graz, Steiermark
Kepler Universitätsklinikum, Linz, Not set
Landeskrankenhaus Rankweil, Rankweil, Not set
Local Institution - 0250, Wien, Not set
Cliniques universitaires Saint-Luc, Brussels, Bruxelles-Capitale, Région De
UZ Gent, Gent, Oost-Vlaanderen
VITAZ, Sint-Niklaas, Oost-Vlaanderen
Local Institution - 0180, Leuven, Vlaams-Brabant
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, Not set
Local Institution - 0166, Fortaleza, Ceará
Local Institution - 0165, Porto Alegre, Rio Grande Do Sul
Local Institution - 0169, Porto Alegre, Rio Grande Do Sul
Local Institution - 0170, Santa Cruz do Sul, Rio Grande Do Sul
Local Institution - 0163, Itajaí, Santa Catarina
Local Institution - 0178, Barretos, São Paulo
Local Institution - 0111, Sao Paulo, São Paulo
Local Institution - 0289, Edmonton, Alberta
CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski, Rimouski, Quebec
IUCPQ, Quebec, Not set
Orlandi Oncologia, Santiago, Región Metropolitana De Santiago
Fundacion Arturo Lopez Perez (FALP), Santiago, Región Metropolitana De Santiago
Pontificia Universidad Catolica de Chile, Santiago, Región Metropolitana De Santiago
Bradfordhill, Santiago, Región Metropolitana De Santiago
Oncocentro Apys, Viña del Mar, Valparaíso
Beijing Cancer hospital, Beijing, Beijing
Beijing Chest Hospital,Capital Medical University, Beijing, Beijing
Chongqing University Cancer Hospital, Chongqing, Chongqing
Fujian Cancer Hospital, Fuzhou, Fujian
Local Institution - 0212, Xiamen, Fujian
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong
Local Institution - 0227, Harbin, Heilongjiang
Local Institution - 0208, Wuhan, Hubei
Hubei Cancer Hospital, Wuhan, Hubei
Local Institution - 0216, Changsha, Hunan
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi
Jilin Province Tumor Hospital, Changchun, Jilin
Local Institution - 0235, Shenyang, Liaoning
Xi'an International Medical Center Hospital, Xi'an, Shaanxi
Shandong Cancer Hospital, Jinan, Shandong
Local Institution - 0206, Shanghai, Shanghai
Zhongshan Hospital,Fudan University, Shanghai, Shanghai
Sichuan Cancer hospital, Chengdu, Sichuan
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang
Shanghai East Hospital, Shanghai, Not set
Masarykuv onkologicky ustav, Brno, Brno-město
Nemocnice AGEL Ostrava - Vitkovice a.s., Ostrava, Ostrava Město
Fakultni Thomayerova nemocnice, Prague, Praha 4
Fakultni nemocnice Olomouc, Olomouc, Not set
Hôpital Arnaud de Villeneuve - CHU Montpellier, Montpellier, Hérault
Chu Grenoble Alpes, La Tronche, Isère
CHU Lille - Institut Coeur Poumon, Lille Cedex, Nord
L Hopital Nord Ouest, Gleize, Rhône
Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône
Centre Hospitalier Intercommunal de Créteil, Créteil, Val-de-Marne
Gustave Roussy, Villejuif, Val-de-Marne
Assistance Publique Hôpitaux de Marseille - Hôpital Nord, Marseille, Not set
Institut Curie, Paris, Not set
Centre Hospitalier de Cornouaille Quimper - Concarneau, Quimper, Not set
Krankenhaus Nordwest GmbH, Frankfurt, Hessen
Pius Hospital Oldenburg, Oldenburg, Niedersachsen
Klinikum Köln-Merheim, Köln, Nordrhein-Westfalen
Krankenhaus Martha-Maria Halle-Dölau, Halle, Sachsen-Anhalt
Zentralklinik Bad Berka, Bad Berka, Thüringen
Local Institution - 0263, Berlin, Not set
Asklepios Klinik Gauting GmbH, Gauting, Not set
LungenClinic Grosshansdorf, Grosshansdorf, Not set
Thoraxklinik-Heidelberg gGmbH, Heidelberg, Not set
Robert Bosch Krankenhaus GmbH, Stuttgart, Not set
Errikos Dunant Hospital Center, Athens, Attikí
Thoracic General Hospital of Athens "I Sotiria", Athens, Attikí
"Theagenio" Cancer Hospital of Thessaloniki, Thessaloniki, Kentrikí Makedonía
European Interbalkan Medical Center, Thessaloniki, Thessaloníki
University General Hospital of Larissa, Larissa, Thessalía
Local Institution - 0278, New Delhi, Delhi
Local Institution - 0274, Bengaluru, Karnataka
Local Institution - 0271, Madurai, Tamil Nadu
Local Institution - 0277, Varanasi, Uttar Pradesh
Local Institution - 0273, Kolkata, West Bengal
Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Lombardia
Istituto Nazionale Tumori Regina Elena, Rome, Roma
AO Santa Maria della Misericordia, Perugia, Umbria
Casa di Cura Dott. Pederzoli, Peschiera del Garda, Verona
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set
Istituto Europeo di Oncologia IRCCS, Milano, Not set
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime
Kurume University Hospital, Kurume, Fukuoka
Hokkaido University Hospital, Sapporo, Hokkaido
Kobe City Medical Center General Hospital, Kobe-shi, Hyogo
Kanazawa University Hospital, Kanazawa, Ishikawa
Kanagawa Cardiovascular and Respiratory Center, Yokohama, Kanagawa
Sendai Kousei Hospital, Sendai, Miyagi
Nara Medical University Hospital, Kashihara city, Nara
Kurashiki Central Hospital, Kurashiki, Okayama
Kansai Medical University Hospital, Hirakata, Osaka
Kindai University Hospital- Osakasayama Campus, Osaka Sayama, Osaka
Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Osaka
Saitama Medical University International Medical Center, Hidaka, Saitama
Saitama Prefectural Cancer Center, Ina-machi, Saitama
Hamamatsu University Hospital, Hamamatsu, Shizuoka
Nippon Medical School Hospital, Bunkyo-ku, Tokyo
The Cancer Institute Hospital of JFCR, Koto, Tokyo
Fukushima Medical University, Fukushima, Not set
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do [Chungbuk]
Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do
Ajou University Hospital, Suwon-si, Kyǒnggi-do
Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul]
Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]
Keimyung University Dongsan Hospital, Daegu, Taegu-Kwangyǒkshi
Local Institution - 0311, Kuching, Sarawak
Local Institution - 0310, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Local Institution - 0312, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Local Institution - 0148, Pachuca, Hidalgo
Local Institution - 0146, Guadalajara, Jalisco
Local Institution - 0147, Monterrey, Nuevo León
Local Institution - 0145, Puebla, Not set
Amsterdam UMC, locatie VUmc, Amsterdam, Noord-Holland
Ziekenhuis Rijnstate, Arnhem, Not set
University Medical Center Groningen, Groningen, Not set
Szpital Specjalistyczny w Prabutach Spolka z o.o., Prabuty, Pomorskie
Przychodnia Lekarska KOMED, Konin, Wielkopolskie
Pratia Poznań, Poznań, Wielkopolskie
Centrum Onkologii im. Prof. Franciszka Lukaszczyka, Bydgoszcz, Not set
Instytut Centrum Zdrowia Matki Polki, Łódź, Łódzkie
SC Memorial Healthcare International SRL, Bucharest, București
Institutul Oncologic Bucuresti, Bucharest, București
SC Radiotherapy Center Cluj SRL, Florești, Cluj
Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj
Institutul Oncologic Cluj, Cluj, Not set
S.C. Centrul de Oncologie Euroclinic S.R.L., Iași, Not set
Institutul Regional de Oncologie, Iași, Not set
CHUS - Hospital Clinico Universitario, Santiago de Compostela, A Coruña [La Coruña]
Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]
Hospital de la Santa Creu i Sant Pau, Barcelona, Catalunya [Cataluña]
Hospital Universitario de Jaen, Jaen, Jaén
Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De
Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad De
Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De
Hospital General Universitario de Valencia, Valencia, Valenciana, Comunitat
Local Institution - 0299, Sevilla, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Kantonsspital Graubünden, Chur, Not set
Kantonsspital Winterthur, Winterthur, Not set
UniversitätsSpital Zürich, Zürich, Not set
Local Institution - 0158, Cigli, İzmir
Local Institution - 0154, Adana, Not set
Local Institution - 0157, Ankara, Not set
Local Institution - 0177, Ankara, Not set
Local Institution - 0153, Istanbul, Not set
Local Institution - 0197, London, London, City Of
James Cook University Hospital, Central Middlesbrough, Middlesbrough
Aberdeen Royal Infirmary, Aberdeen, Not set
Local Institution - 0108, Leicester, Not set
The Christie NHS Foundation Trust, Manchester, Not set
The Clatterbridge Cancer Centre, Wirral, Not set
Conditions: Extensive-Stage Small Cell Lung Cancer
Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease
Recruiting
The purpose of this study is to estimate the prevalence, demographic, and clinical characteristics of PKD1/2 gene variant groups in the ADPKD population.
The purpose of this study is to estimate the prevalence, demographic, and clinical characteristics of PKD1/2 gene variant groups in the ADPKD population. Read Less
Gender:
ALL
Ages:
Between 12 years and 65 years
Trial Updated:
08/21/2025
Locations: Alabama Kidney Research, Alabaster, Alabama +39 locations
Alabama Kidney Research, Alabaster, Alabama
Kaiser Permanente - Los Angeles Medical Center, Los Angeles, California
UCLA Division of Nephrology, Los Angeles, California
Helen Diller Medical Center at Parnassus Heights, San Francisco, California
Nephrology & Hypertension Associates, PC, Middlebury, Connecticut
Yale Nephrology Clinical Research Clinic, New Haven, Connecticut
Nature Coast Clinical Research - Inverness, Inverness, Florida
Mayo Clinic - Jacksonville, Jacksonville, Florida
Emory School of Medicine - Renal Division, Atlanta, Georgia
Renal Associates, LLC, Columbus, Georgia
UChicago Medicine - Duchossois Center for Advanced Medicine - Nephrology, Chicago, Illinois
University of Iowa Hospital & Clinics, Iowa City, Iowa
University of Kansas Medical Center, Kansas City, Kansas
General Clinical Research Center, University of Maryland Baltimore, Baltimore, Maryland
Tufts Medical Center, Boston, Massachusetts
Beth Israel Deaconess Medical Center - Nephrology, Boston, Massachusetts
Quest Research Institute, Farmington Hills, Michigan
Mayo Clinic - Rochester, Rochester, Minnesota
DaVita Clinical Research, Las Vegas, Nevada
Columbia University Medical Center, New York, New York
Perelman Center for Advanced Medicine - Nephrology, Philadelphia, Pennsylvania
UVM Medical Center - 1 South Prospect Street, Burlington, Vermont
Swedish Center for Comprehensive Care, Seattle, Washington
Universite Catholique de Louvain, Cliniques universitaires Saint-Luc (UCLouvain), Brussels, Not set
Universitaire Ziekenhuizen Leuven, Leuven, Not set
St. Joseph's Healthcare - Hamilton, Hamilton, Not set
McGill University Health Centre, Glen Site, Montreal, Not set
Hopital de la Cavale Blanche, Brest, Not set
Necker Hospital, Paris, Not set
Charité - Paediatric Pulmonology Department, Berlin, Not set
Universitaetsklinik Koeln Department II of Internal Medicine, Cologne, Not set
UMCG - Nephrology, Groningen, Not set
Erasmus Medisch Centrum - Nephrology, Rotterdam, Not set
FDI Clinicial Research, San Juan, Not set
Hospital Fundacion Jimenez Diaz, Madrid, Not set
King's College Hospital, London, Not set
Royal Free NHS Trust, London, Not set
St Georges University Hospitals NHS Foundation Trust, London, Not set
Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital - Nephrology, Newcastle Upon Tyne, Not set
Northern General Hospital, Sheffield, Not set
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)
Recruiting
The goal of this clinical trial is to evaluate the impact that ENV-101 has on lung function and key measures of fibrosis in adult patients with idiopathic pulmonary fibrosis (IPF). Another goal of this study is to better understand the safety and tolerability of ENV-101 in this patient population.
The goal of this clinical trial is to evaluate the impact that ENV-101 has on lung function and key measures of fibrosis in adult patients with idiopathic pulmonary fibrosis (IPF). Another goal of this study is to better understand the safety and tolerability of ENV-101 in this patient population. Read Less
Gender:
ALL
Ages:
40 years and above
Trial Updated:
08/21/2025
Locations: Research Site, Quilmes, Buenos Aires +80 locations
Research Site, Quilmes, Buenos Aires
Research Site, Buenos Aires, Not set
Research Site, Buenos Aires, Not set
Research Site, Mendoza, Not set
Research Site, Mendoza, Not set
Research Site, Camperdown, New South Wales
Research Site, Macquarie Park, New South Wales
Research Site, Brisbane, Queensland
Research Site, South Brisbane, Queensland
Research Site, Adelaide, South Australia
Research Site, Box Hill, Victoria
Research Site, Melbourne, Victoria
Research Site, Nedlands, Western Australia
Research Site, Graz, Steiermark
Research Site, Vienna, Not set
Research Site, Dinant, Namur
Research Site, Brussels, Not set
Research Site, Brussels, Not set
Research Site, Edmonton, Alberta
Research Site, Vancouver, British Columbia
Research Site, Ajax, Ontario
Research Site, Montréal, Quebec
Research Site, Sherbrooke, Quebec
Research Site, Trois-Rivières, Quebec
Research Site, Angers, Not set
Research Site, Bordeaux, Not set
Research Site, Caen, Not set
Research Site, Dijon, Not set
Research Site, Montpellier, Not set
Research Site, Nantes, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Rennes, Not set
Research Site, Tours, Not set
Research Site, Giessen, Hessen
Research Site, Immenhausen, Hessen
Research Site, Hannover, Lower Saxony
Research Site, Essen, North Rhine-Westphalia
Research Site, Berlin, Not set
Research Site, Leipzig, Not set
Research Site, Dublin, Leinster
Research Site, Dublin, Leinster
Research Site, Cork, Munster
Research Site, Dublin, Not set
Research Site, Bologna, Forli-Cesena
Research Site, Padova, Padua
Research Site, Florence, Tuscany
Research Site, Catania, Not set
Research Site, Milan, Not set
Research Site, Turin, Not set
Research Site, Seoul, (Deogyang District)
Research Site, Ulsan, (Dong District)
Research Site, Seoul, (Gangnam District)
Research Site, Busan, (Haeundae District)
Research Site, Seoul, (Seongbuk District)
Research Site, Seoul, (Songpa District)
Research Site, Seoul, (Yongsan District)
Research Site, Seoul, Not set
Research Site, Kuala Lumpur, Selangor
Research Site, Kuala Lumpur, Selangor
Research Site, Kuala Lumpur, Selangor
Research Site, Monterrey, Nuevo Leon
Research Site, Monterrey, Nuevo Leon
Research Site, San Nicolás De Los Garza, Nuevo Leon
Research Site, San Juan Del Río, Queretaro
Research Site, Chihuahua, Not set
Research Site, Mexico City, Not set
Research Site, Oaxaca, Not set
Research Site, Puebla, Not set
Research Site, Auckland, Not set
Research Site, Christchurch, Not set
Research Site, Hamilton, Not set
Research Site, Belfast, Not set
Research Site, Birmingham, Not set
Research Site, Birmingham, Not set
Research Site, Cambridge, Not set
Research Site, Edinburgh, Not set
Research Site, Exeter, Not set
Research Site, Leicester, Not set
Research Site, Londonderry, Not set
Research Site, London, Not set
Conditions: Idiopathic Pulmonary Fibrosis, Progressive Fibrosing Interstitial Lung Disease
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma (GOLSEEK-4)
Recruiting
The study is designed as a multicenter, randomized, open label Phase 3 study to compare the efficacy and safety of golcadomide in combination with rituximab vs investigator's choice in participants with relapsed/refractory follicular lymphoma who have received at least one line of prior systemic therapy.
The study is designed as a multicenter, randomized, open label Phase 3 study to compare the efficacy and safety of golcadomide in combination with rituximab vs investigator's choice in participants with relapsed/refractory follicular lymphoma who have received at least one line of prior systemic therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: Local Institution - 0225, Birmingham, Alabama +153 locations
Local Institution - 0225, Birmingham, Alabama
Local Institution - 0014, Mobile, Alabama
Alaska Oncology and Hematology, Anchorage, Alaska
Local Institution - 0215, Little Rock, Arkansas
Local Institution - 0072, Duarte, California
Local Institution - 0119, San Francisco, California
Local Institution - 0008, Jacksonville, Florida
Local Institution - 0214, Tampa, Florida
Local Institution - 0217, Tampa, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital, Marietta, Georgia
Local Institution - 0245, Newnan, Georgia
Local Institution - 0240, Arlington Heights, Illinois
Local Institution - 0253, Iowa City, Iowa
Local Institution - 0243, Waukee, Iowa
Local Institution - 0216, Westwood, Kansas
Local Institution - 0218, Lexington, Kentucky
Local Institution - 0023, Baltimore, Maryland
Greater Baltimore Medical Center, Towson, Maryland
Local Institution - 0145, Boston, Massachusetts
Local Institution - 0244, Boston, Massachusetts
Local Institution - 0247, Boston, Massachusetts
Hattiesburg Clinic Hematology/Oncology, Hattiesburg, Mississippi
Local Institution - 0144, Providence, Rhode Island
Local Institution - 0237, Austin, Texas
Local Institution - 0212, Fort Worth, Texas
Local Institution - 0230, San Antonio, Texas
Local Institution - 0236, Tyler, Texas
Local Institution - 0238, Fairfax, Virginia
Hematology Oncology Associates of Fredericksburg, Fredericksburg, Virginia
Local Institution - 0146, Roanoke, Virginia
Local Institution - 0143, Vancouver, Washington
Local Institution - 0134, Westmead, New South Wales
Local Institution - 0132, Adelaide, South Australia
Local Institution - 0131, Hobart, Tasmania
Local Institution - 0128, Heidelberg, Victoria
Local Institution - 0198, Malvern, Victoria
Local Institution - 0127, Perth, Western Australia
Local Institution - 0224, Perth, Western Australia
Local Institution - 0159, Vitoria, Espírito Santo
Local Institution - 0088, Niterói, Rio De Janeiro
Local Institution - 0087, Porto Alegre, Rio Grande Do Sul
Local Institution - 0079, Sao Paulo, São Paulo
Local Institution - 0089, Rio de Janeiro, Not set
Local Institution - 0066, São Paulo, Not set
Local Institution - 0092, São Paulo, Not set
Local Institution - 0200, Victoria, British Columbia
Princess Margaret Cancer Centre, Toronto, Ontario
Local Institution - 0250, Québec, Quebec
Local Institution - 0192, Sherbrooke, Quebec
Local Institution - 0226, Sherbrooke, Quebec
Local Institution - 0154, Santiago, Región Metropolitana De Santiago
Local Institution - 0155, Santiago, Región Metropolitana De Santiago
Local Institution - 0153, Santiago, Región Metropolitana De Santiago
Local Institution - 0246, Beijing, Beijing
Local Institution - 0171, Beijing, Beijing
Local Institution - 0172, Fuzhou Fujian, Fujian
Local Institution - 0173, Guangzhou, Guangdong
Local Institution - 0241, Harbin, Heilongjiang
Local Institution - 0176, Wuhan, Hubei
Local Institution - 0175, Changsha, Hunan
Local Institution - 0235, Hohhot, Inner Mongolia
Local Institution - 0233, Suzhou, Jiangsu
Local Institution - 0178, Nanchang, Jiangxi
Local Institution - 0239, Changchun, Jilin
Local Institution - 0177, Changchun, Jilin
Local Institution - 0179, Shenyang, Liaoning
Local Institution - 0242, Shenyang, Liaoning
Local Institution - 0180, Jinan, Shandong
Local Institution - 0181, Shanghai, Shanghai
Local Institution - 0249, Shanghai, Shanghai
Local Institution - 0234, Sichuan, Sichuan
Local Institution - 0182, Tianjin, Tianjin
Local Institution - 0227, Tianjin, Tianjin
Local Institution - 0248, Kunming, Yunnan
Local Institution - 0184, Hangzhou, Zhejiang
Local Institution - 0174, Zhengzhou, Not set
Local Institution - 0151, Oulu, Pohjois-Pohjanmaa
Local Institution - 0152, Turku, Varsinais-Suomi
Local Institution - 0150, Helsinki, Not set
Local Institution - 0100, Pessac, Aquitaine
Local Institution - 0044, Saint-Cloud, Hauts-de-Seine
Local Institution - 0047, Montpellier, Languedoc-Roussillon
Local Institution - 0120, Nantes, Loire-Atlantique
Local Institution - 0048, Lille, Nord
Local Institution - 0042, Pierre-Bénite, Rhône
Local Institution - 0191, Paris, Not set
Local Institution - 0121, Toulouse, Not set
Local Institution - 0163, Ulm, Baden-Württemberg
Local Institution - 0161, Augsburg, Bayern
Local Institution - 0220, Göttingen, Niedersachsen
Local Institution - 0166, Dortmund, Nordrhein-Westfalen
Local Institution - 0193, Düsseldorf, Nordrhein-Westfalen
Local Institution - 0231, Münster, Nordrhein-Westfalen
Local Institution - 0232, Münster, Nordrhein-Westfalen
Local Institution - 0164, Homburg, Saarland
Local Institution - 0165, Chemnitz, Sachsen
Local Institution - 0222, Erfurt, Thüringen
Local Institution - 0167, Jena, Thüringen
Local Institution - 0187, Dresden, Not set
Local Institution - 0162, München, Not set
Local Institution - 0221, Wuerzburg, Not set
Local Institution - 0109, Athens, Attikí
Local Institution - 0107, Αthens, Attikí
Local Institution - 0110, Thessaloniki, Thessaloníki
Local Institution - 0197, Thessaloniki, Thessaloníki
Local Institution - 0111, Alexandroupolis, Not set
Local Institution - 0108, Ioannina, Ípeiros
Local Institution - 0142, New Delhi, Delhi
Local Institution - 0139, Bengaluru, Karnataka
Local Institution - 0141, Mumbai, Maharashtra
Local Institution - 0140, Hyderabad, Telangana
Local Institution - 0138, Hyderabad, Telangana
Local Institution - 0104, Bologna, Emilia-Romagna
Local Institution - 0101, Meldola, Emilia-Romagna
Local Institution - 0103, Rozzano, Milano
Local Institution - 0106, Pisa, Toscana
Local Institution - 0102, Alessandria, Not set
Local Institution - 0105, Napoli, Not set
Local Institution - 0157, Torino, Not set
Aiiku Hospital, Sapporo, Hokkaido
Japanease Red Cross Society Himeji Hospital, Himeji, Hyogo
Local Institution - 0201, Morioka, Iwate
University of Yamanashi Hospital, Chuo, Yamanashi
Local Institution - 0059, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0060, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0061, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0058, Seoul, Not set
Local Institution - 0050, Amsterdam, Noord-Holland
Local Institution - 0046, Groningen, Not set
Local Institution - 0053, Utrecht, Not set
Local Institution - 0188, Warszawa, Mazowieckie
Local Institution - 0186, Kraków, Małopolskie
Local Institution - 0190, Gdynia, Pomorskie
Local Institution - 0185, Skórzewo, Wielkopolskie
Local Institution - 0189, Łódź, Łódzkie
Local Institution - 0099, Dammam, Ash Sharqīyah
Local Institution - 0054, Riyadh, Not set
Local Institution - 0052, Riyadh, Not set
Local Institution - 0158, Sabadell, Barcelona [Barcelona]
Local Institution - 0122, Santander, Cantabria
Local Institution - 0124, Madrid, Madrid, Comunidad De
Local Institution - 0125, Valencia, Valenciana, Comunitat
Local Institution - 0126, Granada, Not set
Local Institution - 0123, Madrid, Not set
Local Institution - 0195, Istanbul- Fatih, İstanbul
Local Institution - 0194, Ankara, Not set
Local Institution - 0196, Antalya, Not set
Local Institution - 0223, Mersin, Not set
Local Institution - 0251, Abu Dhabi, Abū Z̧aby
Local Institution - 0252, Abu Dhabi, Abū Z̧aby
Norfolk and Norwich University Hospitals NHS Foundation Trust, Cringleford, England
Kent and Canterbury Hospital, Canterbury, Kent
Local Institution - 0213, London, London, City Of
Local Institution - 0149, Manchester, Not set
Conditions: Follicular Lymphoma
First in Human Study of IMGN151 in Recurrent Gynaecological Cancers
Recruiting
IIMGN151-1001 is a Phase 1, first in human, open-label dose-escalation, optimization, and expansion study designed to characterize the safety, tolerability, pharmacokinetics (PK), immunogenicity, and preliminary antitumor activity of IMGN151 in adult participants with recurrent endometrial cancer; recurrent, high-grade serous epithelial ovarian, fallopian tube, and primary peritoneal cancers; or recurrent cervical cancers. All participants will be, in the opinion of the investigator, appropriate... Read More
IIMGN151-1001 is a Phase 1, first in human, open-label dose-escalation, optimization, and expansion study designed to characterize the safety, tolerability, pharmacokinetics (PK), immunogenicity, and preliminary antitumor activity of IMGN151 in adult participants with recurrent endometrial cancer; recurrent, high-grade serous epithelial ovarian, fallopian tube, and primary peritoneal cancers; or recurrent cervical cancers. All participants will be, in the opinion of the investigator, appropriate for nonplatinum single-agent therapy for their next line of therapy. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: University of Alabama at Birmingham /ID# 269045, Birmingham, Alabama +47 locations
University of Alabama at Birmingham /ID# 269045, Birmingham, Alabama
City of Hope National Medical Center /ID# 269036, Duarte, California
Moores Cancer Center /ID# 269040, La Jolla, California
University of California Los Angeles Medical Center /ID# 269037, Los Angeles, California
Hoag Memorial Hospital Presbyterian /ID# 269047, Newport Beach, California
UCHSC Anschultz Cancer Pavilion /ID# 269056, Aurora, Colorado
AdventHealth Celebration /ID# 269030, Kissimmee, Florida
Mount Sinai Medical Center /ID# 269050, Miami, Florida
Miami Cancer Institute at Baptist Health /ID# 269041, Miami, Florida
Florida Cancer Specialists- Sarasota Cattlemen /ID# 269055, Sarasota, Florida
University of Chicago Medical Center /ID# 269028, Chicago, Illinois
Massachusetts General Hospital /ID# 278119, Boston, Massachusetts
Dana-Farber Cancer Institute /ID# 269039, Boston, Massachusetts
Karmanos Cancer Institute - Detroit /ID# 269052, Detroit, Michigan
University of Mississippi Medical Cancer Center /ID# 269046, Jackson, Mississippi
Washington University School of Medicine - St. Louis /ID# 269048, Saint Louis, Missouri
Holy Name Medical Center /ID# 269051, Teaneck, New Jersey
Roswell Park Cancer Institute /ID# 269043, Buffalo, New York
Long Island Jewish Medical Center /ID# 269035, New Hyde Park, New York
Columbia University Irving Medical Center /ID# 269033, New York, New York
University of Rochester Medical Center /ID# 269044, Rochester, New York
University of North Carolina Medical Center /ID# 269027, Chapel Hill, North Carolina
Levine Cancer Institute /ID# 269049, Charlotte, North Carolina
The Ohio State University Comprehensive Cancer Center /ID# 269026, Columbus, Ohio
Ou Health - Stephenson Cancer Center /ID# 269025, Oklahoma City, Oklahoma
University of Pennsylvania /ID# 269042, Philadelphia, Pennsylvania
West Penn Hospital /ID# 269054, Pittsburgh, Pennsylvania
Women & Infants Hospital /ID# 269032, Providence, Rhode Island
Sanford Cancer Center /ID# 269038, Sioux Falls, South Dakota
Tennessee Oncology Nashville /ID# 269029, Nashville, Tennessee
MD Anderson Houston /ID# 269057, Houston, Texas
University of Virginia /ID# 269053, Charlottesville, Virginia
Monash Health - Monash Medical Centre /ID# 268971, Perth, Western Australia
Hôpital Vivalia De Libramont /ID# 268979, Libramont-Chevigny, Luxembourg
Cross Cancer Institute /ID# 268984, Edmonton, Alberta
BC Cancer - Kelowna /ID# 268983, Kelowna, British Columbia
DKD Helios Klinik Wiesbaden /ID# 269011, Wiesbaden, Not set
Mater Misericordiae University Hospital /ID# 269013, Dublin, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 269020, Rome, Roma
Erasmus Medisch Centrum /ID# 269022, Rotterdam, Zuid-Holland
Universitair Medisch Centrum Groningen /ID# 269023, Groningen, Not set
Universitair Medisch Centrum Utrecht /ID# 269024, Utrecht, Not set
Institut Català d'Oncologia (ICO) - Badalona /ID# 268990, Badalona, Barcelona
Hospital Universitario Reina Sofia /ID# 269656, Córdoba, Cordoba
Hospital MD Anderson Cancer Center Madrid /ID# 268991, Madrid, Not set
Hospital Universitario Ramón y Cajal /ID# 268992, Madrid, Not set
Hospital Universitario La Paz /ID# 268987, Madrid, Not set
Hospital Clínico Universitario de Valencia /ID# 268988, Valencia, Not set
Conditions: Endometrial Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer, Cervical Cancer
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Recruiting
This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular ejection fraction (LVEF) of 40% or more. The purpose of this study is to find out whether vicadrostat (BI 690517) in combination with empagliflozin helps people with heart failure.
Participants are put into 2 groups by chance. Every participant has an equal chance of being in each group. The groups are:
* Vicadrostat and empagliflozin... Read More
This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular ejection fraction (LVEF) of 40% or more. The purpose of this study is to find out whether vicadrostat (BI 690517) in combination with empagliflozin helps people with heart failure.
Participants are put into 2 groups by chance. Every participant has an equal chance of being in each group. The groups are:
* Vicadrostat and empagliflozin group: participants take vicadrostat and empagliflozin as tablets once a day.
* Placebo and empagliflozin group: participants take placebo and empagliflozin as tablets once a day.
Participants can stay in the study as long as they benefit from treatment and can tolerate it. During this time, they visit their doctors regularly. The doctors regularly check participants' health and take note of any unwanted effects. The study staff may also contact the participants by phone. Participants also regularly answer questions about their well-being.
The study does not have a fixed duration. It continues until there is enough data to see if the treatment is working. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: Diagnostic and Medical Clinic, Mobile, Alabama +574 locations
Diagnostic and Medical Clinic, Mobile, Alabama
Mobile Heart Specialists, PC, Mobile, Alabama
Velocity Clinical Research-Chula Vista-67286, Chula Vista, California
University of California Irvine, Orange, California
North America Research Institute, San Dimas, California
Orange County Research Center, Tustin, California
Amicis Research Center (ARC), Valencia, California
Bridgeport Hospital, Bridgeport, Connecticut
Excel Medical Clinical Trials, Boca Raton, Florida
Bay Area Cardiology, Brandon, Florida
Clearwater Cardiovascular and Interventional Consultants, Clearwater, Florida
Cardiology Associates Research Co., Daytona Beach, Florida
Malcom Randall VA Medical Center, Gainesville, Florida
Velocity Clinical Research-Hallandale Beach-67888, Hallandale Beach, Florida
University of Florida Health Jacksonville, Jacksonville, Florida
East Coast Institute for Research, LLC-Jacksonville-55146, Jacksonville, Florida
First Coast Cardiovascular Institute, Jacksonville, Florida
Clearwater Cardiovascular Consultants-Largo-69917, Largo, Florida
University of Miami, Miami, Florida
Sacred Heart Medical Specialty Group, Miramar Beach, Florida
Advanced Research for Health Improvement, LLC, Naples, Florida
Southwest Florida Research, LLC, Naples, Florida
Ocala Cardiovascular Research, Ocala, Florida
Ocala Research Institute, Inc, Ocala, Florida
Charlotte Cardiovascular Institute, PA, Port Charlotte, Florida
East Coast Institute for Research, LLC-Saint Augustine-63032, Saint Augustine, Florida
University of South Florida, Tampa, Florida
Cardiology Partners Clinical Research Institute, Wellington, Florida
Cozy Research LLC, Wesley Chapel, Florida
Clinical Site Partners, LLC, Winter Park, Florida
Atlanta Clinical Research Centers, Atlanta, Georgia
Columbus Regional Research Institute, Columbus, Georgia
NSC Research Inc, Johns Creek, Georgia
Kootenai Medical Center, Coeur d'Alene, Idaho
Northwest Heart Clinical Research, LLC, Arlington Heights, Illinois
Illinois Masonic Hospital, Chicago, Illinois
Chicago Medical Research, Hazel Crest, Illinois
Clinical Investigation Specialists, Inc.-Libertyville-69941, Libertyville, Illinois
AMR Park Ridge, Park Ridge, Illinois
Midwest Cardiovascular Research and Education Foundation, Elkhart, Indiana
St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis, Indiana
Indiana Medical Research Institute, Merrillville, Indiana
Cardiovascular Research of Northwest Indiana, LLC, Munster, Indiana
Reid Hospital, Richmond, Indiana
The Iowa Clinic, PC, West Des Moines, Iowa
West Houston Area Clinical Trial Consultants, LLC, Wichita, Kansas
Norton Heart Specialists, Louisville, Kentucky
Grace Research, LLC-Bossier City-51040, Bossier City, Louisiana
Heart Clinic of Hammond, Hammond, Louisiana
Grace Research, LLC-Shreveport-64616, Shreveport, Louisiana
Louisiana Heart Center - Slidell, Slidell, Louisiana
Ascension Saint Agnes Heart Care, Baltimore, Maryland
AMR Dearborn, Dearborn, Michigan
Sparrow Clinical Research Institute, Lansing, Michigan
Trinity Health Michigan D/B/A Michigan Heart, Ypsilanti, Michigan
Minneapolis VA Health Care System, Minneapolis, Minnesota
Jackson Heart Clinic, P.A., Jackson, Mississippi
Kansas City VA Medical Center, Kansas City, Missouri
North Kansas City Hospital, North Kansas City, Missouri
St. Louis Heart and Vascular, P.C., Saint Louis, Missouri
Velocity Clinical Research-Lincoln-69943, Lincoln, Nebraska
Advanced Heart Care, LLC, Bridgewater, New Jersey
Garden State Heart Care, PC, Manalapan, New Jersey
Cardio Metabolic Institute, Somerset, New Jersey
Cardiac Care and Vascular Medicine, PLLC, Bronx, New York
NYU Langone Health, New York, New York
Mount Sinai Hospital-New York-52529, New York, New York
Medication Management, LLC, Greensboro, North Carolina
WakeMed, Raleigh, North Carolina
K and R Research LLC, Marion, Ohio
Mercy Health St. Vincent Medical Center, Toledo, Ohio
Bon Secours Medical Group Greenville Specialty Care, LLC, Greenville, South Carolina
Monument Health, Rapid City, South Dakota
Helios CR Inc, Jackson, Tennessee
East Coast Institute For Research LLC, Jefferson City, Tennessee
Pharmatex Research, Amarillo, Texas
Amarillo Heart Clinical Research Institute, Incorporated, Amarillo, Texas
Texas Health Research and Education Institute, Dallas, Texas
Texas Health Research and Education Institute, Dallas, Texas
Southwest Family Medicine Associates, Dallas, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
Helios CR Inc, Fort Worth, Texas
Private Practice Leadership, LLC, Katy, Texas
Texas Cardiology Research Center PLLC, Kingwood, Texas
DCOL Center for Clinical Research, Longview, Texas
North Texas Research Associates, McKinney, Texas
Texas Institute Of Cardiology, McKinney, Texas
University of Utah Hospital, Salt Lake City, Utah
Carient Heart and Vascular, Manassas, Virginia
Sentara Norfolk General Hospital, Norfolk, Virginia
Selma Medical Associates, Winchester, Winchester, Virginia
Virginia Mason Medical Center, Seattle, Washington
Drug Research and Analysis Corporation, Madison, Wisconsin
ProHealth Care Research Institute and Cardiology Associates, Waukesha, Wisconsin
Inst de Inv Clinicas-Bahia Blanca, Bahia Blanca, Not set
Swiss Medical Center Barrio Parque, Buenos Aire, Not set
Centro de Investigaciones Metabolicas (CINME)-Ciudad Autonoma Buenos Aires-41221, Ciudad Autonoma Buenos Aires, Not set
Mautalen- Salud e Investigacion, Ciudad Autonoma Buenos Aires, Not set
Centro Medico Dra Laura Maffei, Ciudad Autonoma Buenos Aires, Not set
Fundacion Favaloro, Ciudad Autonoma Buenos Aires, Not set
Instituto Cardiovascular de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set
Glenny Corp. S.A. Bioclinica Argentina, Ciudad Autonoma Buenos Aires, Not set
Centro Medico Viamonte, Ciudad Autonoma de Bs As, Not set
Hospital Italiano de Buenos Aires, Ciudad Autónoma de Bs As, Not set
Instituto Medico Elsa Perez SRL (IMEP), Ciudadela, Not set
Clinica Privada Colombo- Fundacion Clinica Colombo, Cordoba, Not set
Instituto Médico DAMIC S.R.L., Cordoba, Not set
Centro Medico Luquez, Cordoba, Not set
Clinica Coronel Suárez, Coronel Suarez, Not set
Sanatorio Allende S.A., Córdoba, Not set
Well Medica, Córdoba, Not set
Centro de Investigaciones Medicas Mar del Plata, Mar del Plata, Not set
Hospital Universitario Austral, Pilar, Not set
Instituto de Investigaciones Clínicas de Quilmes, Quilmes, Not set
DIM Clinica Privada, Ramos Mejía, Not set
Instituto de Investigaciones Clinicas de Rosario, Rosario, Not set
Instituto CAICI, Rosario, Not set
Centro Cardiovascular Salta, Salta, Not set
Corporacion Medica de Gral. San Martin S.A., San Martin, Not set
Investigaciones Clinicas Tucuman, San Miguel de Tucuman, Not set
Clinica Mayo, San Miguel de Tucuman, Not set
Instituto de Investigaciones Clinicas San Nicolas, San Nicolas, Not set
Centro de Investigaciones Clínicas del Litoral, Santa Fe, Not set
CEMEDIC - Centro de Especialidades Medicas, Villa Luro, Not set
Canberra Hospital, Garran, Australian Capital Territory
Concord Repatriation General Hospital, Concord, New South Wales
Gosford Hospital, Gosford, New South Wales
Nepean Hospital, Kingswood, New South Wales
Pendlebury Research, Kotara, New South Wales
Royal Brisbane and Women's Hospital, Brisbane, Queensland
Prince Charles Hospital, Chermside, Queensland
John Flynn Private Hospital, Tugun, Queensland
Royal Adelaide Hospital, Adelaide, South Australia
The Queen Elizabeth Hospital, Woodville, South Australia
Total Cardiovascular Care, Frankston, Victoria
Royal Melbourne Hospital, Parkville, Victoria
Mount Hospital, Perth, Western Australia
Ziekenhuis Oost-Limburg - Campus Sint-Jan, Genk, Not set
AZ Sint-Lucas - Campus Sint Lucas, Gent, Not set
Grand Hôpital de Charleroi, Gilly, Not set
Jessa Ziekenhuis, Hasselt, Not set
Kortrijk - HOSP AZ Groeninge Kennedylaan, Kortrijk, Not set
UZ Leuven, Leuven, Not set
Hospital Vera Cruz, Belo Horizonte, Not set
Cardresearch Cardiologia Assistencial e de Pesquisas Ltda, Belo Horizonte, Not set
L2IP -Instituto de Pesquisas Clínicas Ltda., Brasilia, Not set
CECAP - Centro de Cardiologia Clínica, Brasília, Not set
Hospital Angelina Caron, Campina Grande do Sul, Not set
IPECC - Instituto de Pesquisa Clínica de Campinas, Campinas, Not set
Centro Especializado em Cardiol Loema Instituto de Pesq Clin, Campinas, Not set
Hospital do Rocio, Campo Largo, Not set
PUC Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da PUC-PR, Curitiba, Not set
Via Medica, Goiânia, Not set
ICM - Instituto do Coracao de Marilia, Marília, Not set
Instituto Mederi de Pesquisa e Saude, Passo Fundo, Not set
Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Not set
Hospital de Clínicas de Porto Alegre, Porto Alegre, Not set
Universidade Federal do Rio Grande do Sul, Porto Alegre, Not set
Hospital Mae de Deus, Porto Alegre, Not set
Hospital das Clínicas FMRP-USP, Ribeirão Preto, Not set
Instituto Brasil de Pesquisa Clinica (IBPClin), Rio de Janeiro, Not set
Ruschel Medicina e Pesquisa Clínica, Rio Do Janeiro, Not set
Pesquisare, Santo Andre, Not set
Praxis Pesquisa Medica, Santo Andre, Not set
Fundacao Faculdade Regional de Medicina, Sao Jose, Sao Jose Rio Preto, Not set
Centro de Pesquisa Clinica - CPCLIN, Sao Paulo, Not set
CEPIC - Centro Paulista de Investigacao Clinica, Sao Paulo, Not set
CEDOES - Diagnóstico e Pesquisa,Vitória, Vitória, Not set
Integral Pesquisa e Ensino, Votuporanga, Not set
Ambulatory for Individual Practice for Specialized Medical Care in Cardiology - Dr Nikolay Iliev, Pleven, Not set
Medical Center Medconsult Pleven LTD, Pleven, Not set
Multiprofile Hospital for Active Treatment Heart and Brain EAD, Pleven, Not set
UMHAT Sv.Georgi, Plovdiv, Not set
National Multiprofile Transport Hospital, Sofia, Sofia, Not set
Diagnostic Consultative Center Alexandrovska, Sofia, Not set
University Multidisciplinary Hospital for Active Treatment Sveta Ekaterina EAD, Sofia, Not set
University Multiprofile Hospital for Active Treatement "Alexandrovska" EAD, Sofia, Not set
Medical Center Hera EOOD, Sofia, Not set
MHAT "Tsaritsa Yoanna-ISUL" Clinic of Cardiology, Sofia, Sofia, Not set
Multiprofile Hospital MHATEM 'Pirogov', Sofia, Sofia, Not set
Kalimat Medical Center Ltd., Sofia, Not set
Medical Center Zara-Med EOOD, Stara Zagora, Not set
DCC 'Chaika', EOOD, Varna, Varna, Not set
MHAT St Panteleimon, Yambol, Not set
MHAT St Panteleimon, Yambol, Not set
Cambridge Cardiac Care Centre, Cambridge, Ontario
Curnew Medicine Professional Corporation, Hamilton, Ontario
KMH Cardiology Centres (Mississauga), Mississauga, Ontario
Oakville Trafalgar Memorial Hospital, Oakville, Ontario
James Cha, MD, Oshawa, Ontario
Kawartha Cardiology Clinical Trials, Peterborough, Ontario
CardioQuest Research Centre, Sarnia, Ontario
KMH Cardiology Centers (Hamilton), Stoney Creek, Ontario
Diabetes Heart Research Centre, Toronto, Ontario
ViaCar Recherches Cliniques Inc. (Greenfield Park), Greenfield Park, Quebec
Jewish General Hospital, Montreal, Quebec
Diex Recherche (Trois-Rivieres), Trois-Rivières, Quebec
Royal Alexandra Hospital, Edmonton, Not set
Clinical Research Solutions Inc. (Kitchener), Kitchener, Not set
Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Not set
Montreal General Hospital - McGill University Health Centre, Montreal, Not set
CardioVasc HR Inc., St. Jean sur Richelieu, Not set
Health Sciences North, Sudbury, Not set
Quantum Research Santiago, Puerto Varas, Puerto Varas, Not set
Sociedad Medica Cardiologica El Llano, Santiago, Not set
Hospital Las Higueras, Talcahuano, Not set
CECMI Ltda, Temuco, Not set
CINVEC - Centro de Investigacion Clinica V Reg.,Vina del Mar, Viña del Mar, Not set
The First Affiliated Hospital of Baotou Medical College, Baotou, Not set
Baotou Central Hospital, Baotou, Not set
Beijing AnZhen Hospital, Beijing, Not set
Cardiovascular Institute and Fu Wai Hospital, Beijing, Not set
Peking University Third Hospital, Beijing, Not set
Jilin Province People's Hospital, Changchun, Not set
The First Hospital of Jilin University, Changchun, Not set
China-Japan Union Hospital of Jilin University, Changchun, Not set
Changde Second People's Hospital, Changde City, Not set
Changsha Central Hospital, Changsha, Not set
The Second Xiangya Hospital Of Central South University, Changsha, Not set
The third xiangya hospital of Central South University, Changsha, Not set
The Third Hospital of Changsha, Changsha, Not set
Chengdu Second People's Hospital, Chengdu, Not set
West China Hospital of Sichuan University, Chengdu, Not set
The First Affiliated Hospital of Chengdu Medical College, Chengdu, Not set
Chenzhou No.1 people's Hospital, Chenzhou, Not set
Affiliated Zhongshan Hospital of Dalian University, Dalian, Not set
Daqing Oilfield General Hospital, Daqing City, Not set
People's Hospital of Deyang City, Deyang, Not set
The First People's Hospital of Foshan, Foshan, Not set
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Not set
No.900 Hospital of PLA Joint Logistics Support Force, Fuzhou, Not set
Guangdong Provincial People's Hospital, Guangzhou, Not set
Sun yet-sen Memorial Hospital, Sun yet-sen Univesity, Guangzhou, Not set
Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Not set
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Not set
The Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou, Not set
The Affiliated Hospital of Guizhou Medical University, Guiyang City, Not set
Guizhou People's Hospital, Guiyang, Not set
Hainan General Hospital, Haikou, Not set
Hangzhou First People's Hospital, Hangzhou, Not set
The First Affiliated Hospital of Harbin Medical University, Harbin, Not set
Huainan First People's Hospital, Huainan, Not set
Jiangmen Central Hospital, Jiangmen, Not set
Center Hospital of Jinan, Jinan, Not set
Jining No.1 people's hospital, Jining, Not set
Lanzhou University Second Hospital, Lanzhou, Not set
Linfen Central Hospital, Linfen, Not set
The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Not set
Luoyang Third People's Hospital, Luoyang, Not set
The First Affiliated Hospital of Nanchang University, Nanchang City, Not set
Jiangxi Province Integrated Tractional Chinese Medicine& Western Medicine Hospital, Nanchang, Not set
Nanjing Drum Tower Hospital, Nanjing, Not set
Nanjing Jiangning Hospital, Nanjing, Not set
The First Affiliated Hospital of Guangxi Medical University, Nanning, Not set
Nanyang First People's Hospital, Nanyang, Not set
Nanyang Second General Hospital, Nanyang, Not set
Panjin Liao Oil Gem Flower Hospital, Panjin, Not set
Pingxiang People's Hospital, Pingxiang, Not set
Zhongshan Hospital Affiliated to Fudan University, Shanghai, Not set
Tongren hospital, Shanghai Jiaotong University School of Medicine, Shanghai, Not set
Shanghai General Hospital, Shanghai, Not set
Shengjing Hospital of China Medical University, Shengyang, Not set
Shenzhen People's Hospital, Shenzhen, Not set
The Second Hospital of Hebei Medical University, Shijiazhuang, Not set
Tianjin Union Medical Center Nankai University Affiliated Hospital, Tianjin, Not set
Hubei Province Zhongshan Hospital, Wuhan, Not set
Wuhan Puai Hospital, Wuhan, Not set
Renmin Hospital of Wuhan University, Wuhan, Not set
Shaanxi Provincial People's Hospital, XI An, Not set
Xiangtan Central Hospital, Xiangtan, Not set
The People's Hospital Of Xuancheng City, Xuancheng, Not set
The General Hospital of XZCMG (The Second Affiliated Hospital of Xuzhou Medical University), Xuzhou, Not set
Yanbian University Hospital, Yanji, Not set
The first People's Hosptal of Yinchuan, Yinchuan, Not set
Yueyang Central Hospital, Yueyang, Not set
Yuncheng Central Hospital, Yuncheng, Not set
The First Affiliated Hospital of Hebei North University, Zhangjiakoou, Not set
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set
Affiliated Hospital of Jiangsu University, Zhenjiang, Not set
Cardiomet CEQUIN S.A.S, Armenia, Not set
IPS Centro Cientifico-Asistencial S.A.S, Barranquilla, Not set
Corazon IPS S.A.S., Barranquilla, Not set
Centro de Investigacion Medico Asistencial S.A.S, Barranquilla, Not set
IPS Centro Medico Julián Coronel S.A., Cali, Not set
Centro De Diagnostico Cardiologico Ltda, Cartagena, Not set
Fundacion Cardiovascular de Colombia, Floridablanca, Not set
IPS médicos internistas de Caldas S.A.S., Manizales, Not set
T Y C Inversiones S.A.S Grupsalud, Santa Marta, Not set
Healthy Medical Center S.A.S, Zipaquirá, Zipaquirá, Not set
Medicus Services Ltd., Brandys nad Labem, Not set
Interni Ordinace s.r.o., Brandýs nad Labem, Not set
University Hospital at St. Anna, Brno, Not set
Internal and Cardiology Practice, MUDr. Karel Kamenik, Brno, Brno, Not set
University Hospital Brno, Brno, Not set
Vojenska nemocnice Brno, Brno, Not set
Poliklinika Bílovec, Bílovec, Not set
MUDr. Jan Hubac, s.r.o. Kardiologicka ambulance, Chrudim, Not set
Regional Hospital Havlickuv Brod, Havlickuv Brod, Not set
Kardiologie KarMa s.r.o, Jablonec nad Nisou, Not set
Hospital Jihlava, Jihlava, Not set
MUDr Petra Maskova PhD, Litovel, Not set
InterKardioML s.r.o., Marianske Lazne, Not set
Cardiology and Angiology Private Practice, Prague 10, Not set
Motol University Hospital, Prag, Not set
Kardiologie Vinohrady s r o, Praha 1, Not set
Thomayer University Hospital, Praha 4-Krc, Not set
Institute for Clinical and Experimental Medicine -Praha 4-58982, Praha 4, Not set
Internist Care s r o, Smirice, Not set
Kardiologicka ambulance MUDr. Ferkl s.r.o., Trutnov, Not set
Clinical Trials Services s.r.o, Uherske Hradiste, Not set
MUDr. Nina Zemkova s.r.o., Uherske Hradiste, Not set
Cardio Research s.r.o., Zlin, Not set
Universitätsklinikum Aachen, AöR, Aachen, Not set
Klinikum am Plattenwald, Bad Friedrichshall, Not set
Praxis Dr. Rieker, Berlin, Berlin, Not set
Charite Universitätsmedizin Berlin KöR, Berlin, Not set
Praxis Dr. Toursarkissian, 13347 Berlin, Berlin, Not set
Charité Campus Virchow-Klinikum, Berlin, Not set
Vivantes Netzwerk für Gesundheit GmbH, Berlin, Not set
Vivantes Netzwerk für Gesundheit GmbH, Berlin, Not set
Universitätsklinikum Bonn AöR, Bonn, Not set
Praxis Dr. Menzel, Dessau-Roßlau, Not set
Städtisches Klinikum Dresden, Dresden, Not set
Helios Klinikum Erfurt, Erfurt, Not set
ClinPhenomics CVC GmbH, Frankfurt, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Universitätsklinikum Jena, Jena, Not set
Praxis Joachim Heisters, Kamp-Lintfort, Not set
Asklepios Klinik Langen-Seligenstadt GmbH, Langen, Not set
Praxis Dr. Sarnighausen, Lüneburg, Lüneburg, Not set
Marienhaus Klinikum St. Elisabeth, Neuwied, Neuwied, Not set
Gemeinschaftspraxis Dres Haggenmiller/Jeserich, Nürnberg, Not set
Kardiologische Praxis Papenburg, Papenburg, Not set
Universitätsklinikum Regensburg, Regensburg, Not set
Gemeinschaftspraxis Stuhr-Brinkum, Stuhr, Not set
Praxis Dr. Großkopf Wilma, Wallerfing, Wallerfing, Not set
Kardiologische Praxis, Wermsdorf, Wermsdorf, Not set
Lausmed Kft. Outpatient Unit of Internal Medicine, Baja, Not set
Buda Hospital of the Hospitaller Order of Saint John of God, Budapest, Not set
Obuda Health Center, Budapest, Not set
Belvaros-Lipotvaros Egeszsegugyi Szolgalat, Budapest, Not set
Semmelweis University, Budapest, Not set
Gottsegen National Cardiovascular Center, Budapest, Not set
Semmelweis University, Budapest, Not set
Privat Doktor Egeszseguegyi Szolgaltato Zrt., Budapest, Not set
UNO Medical Trials Kft., Budapest, Not set
Bekes Varmegyei Koezponti Korhaz, Gyula, Not set
BKS Research Ltd, Hatvan, Not set
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz, Miskolc, Not set
IPR Hungary Kft., Miskolc, Not set
Dr. Nagy Laszlo Kardiologiai Maganrendeles, Oroshaza, Not set
Coromed-Smo Kft., Pecs, Not set
Pécsi Tudományegyetem Klinikai Központ, Pecs, Not set
Da Vinci Private Clinic, Pecs, Not set
Ujszeged Egeszsegkozpont Diabetes Centrum, Szeged, Not set
Tolna County Balassa Janos Hospital, Szekszard, Not set
Jasz-Nagykun-Szolnok Megyei Hetenyi G. Korhaz-Rendelointezet, Szolnok, Not set
Belvarosi Egeszseghaz Kft., Zalaegerszeg, Not set
Kamalnayan Bajaj Hospital, Aurangabad, Not set
Narayana Institute of Cardiac Sciences, Bangalore, Not set
Bangalore Medical college, Bengaluru, Not set
S.P. Medical College & Associated Group of Hospitals, Bikaner, Not set
Tamil Nadu Government Multi Super Speciality Hospital TNGMSSH, Chennai, Not set
Apollo Main Hospital, Chennai, Not set
Medanta-The Medicity, Gurgaon, Not set
GNRC Hospital, Guwahati, Not set
IPGMER and SSKM Hospital, Kolkata, Not set
Max Super Speciality Hospital, Delhi, New Delhi, Not set
King George Hospital, Vishakhapatnam, Not set
Humanitas Gavazzeni, Bergamo, Not set
ASST Papa Giovanni XXIII, Bergamo, Not set
Az.Osp. Universitaria "Ospedali Riuniti", Foggia, Not set
Azienda Ospedaliera San Martino, Genova, Not set
Azienda Ospedaliera Universitaria "Federico II", Napoli, Not set
Fondazione IRCCS Policlinico S. Matteo, Pavia, Not set
Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza, Roma, Not set
Istituto Clinico Humanitas, Rozzano, Not set
Kasugai Municipal Hospital, Aichi, Kasugai, Not set
Azumino Red Cross Hospital, Azumino-shi, Not set
Chiba Heart Clinic, Chiba, Chiba, Not set
Tokyo-Eki Center-building Clinic, Chuo-Ku, Not set
Kokura Memorial Hospital, Fukuoka, Kitakyushu, Not set
National Hospital Organization Hamada Medical Center, Hamada-shi, Not set
NHO Mito Medical Center, Higashiibaraki-gun, Not set
Hyogo Prefectural Harima-Himeji General Medical Center, Himeji-shi, Not set
Matsuda Cardiovascular Clinic, Hokkaido, Sapporo, Not set
Oji General Hospital, Hokkaido, Tomakomai, Not set
Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Amagasaki, Not set
National Hospital Organization Kanazawa Medical Center, Ishikawa, Kanazawa, Not set
National Hospital Organization Iwakuni Clinical Center, Iwakuni-shi, Not set
Kagawa Prefectural Central Hospital, Kagawa, Takamatsu, Not set
Tokushukai Shonan Kamakura General Hospital, Kamakura-shi, Not set
Tokushukai Hayama Heart Center, Kanagawa, Miura-gun, Not set
Kanagawa Cardiovascular and Respiratory Center, Kanagawa, Yokohama, Not set
Yokohama Sakae Kyosai Hospital, Kanagawa, Yokohama, Not set
Mitoyo General Hospital, Kanonji-shi, Not set
Tokushukai Kishiwada Tokushukai Hospital, Kishiwada-shi, Not set
North Alps Medical Center Azumi Hospital, Kitaazumi-gun, Not set
National Hospital Organization Kobe Medical Center, Kobe-shi, Not set
Shinshu University Hospital, Matsumoto-shi, Not set
Ehime Prefectural Central Hospital, Matsuyama-shi, Not set
Matsuyama Shimin Hospital, Matsuyama-shi, Not set
Mito Saiseikai General Hospital, Mito-shi, Not set
Hokushin General Hospital, Nakano-shi, Not set
NHO Oita Medical Center, Oita-shi, Not set
Okayama City General Medical Center Okayama City Hospital, Okayama, Okayama, Not set
Naha City Hospital, Okinawa, Naha, Not set
Urasoe General Hospital, Okinawa, Urasoe, Not set
Kitano Hospital, Osaka, Osaka, Not set
Osaka Keisatsu Hospital, Osaka, Osaka, Not set
Nippon Life Hospital, Osaka, Osaka, Not set
Japan Community Health care Organization Osaka Hospital, Osaka, Osaka, Not set
Osaka General Medical Center, Osaka, Osaka, Not set
Saga-Ken Medical Centre Koseikan, Saga-shi, Not set
Sainokuni Higashiomiya Medical Center, Saitama-shi, Not set
San-Ai Hospital, Saitama-shi, Not set
NHO Sendai Medical Center, Sendai-shi, Not set
The University of Osaka Hospital, Suita-shi, Not set
Tokushima Prefectural Central Hospital, Tokushima-shi, Not set
Ome Municipal General Hospital, Tokyo, Ome, Not set
Tomakomai City Hospital, Tomakomai-shi, Not set
Inje University Busan Paik Hospital, Busan, Not set
Dong-A University Hospital, Busan, Not set
Pusan National Univ. Hosp, Busan, Not set
Chonnam National University Hospital, Gwangju, Not set
Gachon University Gil Medical Center, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon State, Not set
Fundación Cardiovascular de Aguascalientes A.C, Aguascalientes, Not set
Hospital Cardiologica Aguascalientes, Aguascalientes, Not set
Centro Medico Culiacán, Culiacan, Not set
Centro de Investigacion Biomedica y Farmaceutica, S.C., Distrito Federal, Not set
CICEJ Centro de Investigacion Clinica Endocrinologica de Jalisco S.C., Guadalajara, Not set
Salud Cardiovascular, Guadalajara, Not set
Proactive CR Mexico S.A. de C.V., Irapuato, Not set
Cardiolink Clin Trials S.C., Monterrey, Not set
Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Not set
Clinstile S.A. de C.V., México, Not set
Clinical Research Institute S.C., Tlalnepantla, Not set
Centro de Investigacion Medica Alberto Bazzoni S.A. de C.V., Torreon, Not set
Rijnstate Hospital, Arnhem, Not set
Amphia Ziekenhuis, Breda, Not set
Deventer Ziekenhuis, Deventer, Not set
Catharina Ziekenhuis, Eindhoven, Not set
Groene Hart ziekenhuis, Gouda, Not set
Alrijne Leiderdorp, Leiderdorp, Not set
St. Antonius ziekenhuis, locatie Nieuwegein, Nieuwegein, Not set
Ikazia Ziekenhuis, Rotterdam, Not set
Jeroen Bosch Ziekenhuis-Hertogenbosch, s Hertogenbosch, Not set
De Heel - Zaans Medisch Centrum, Zaandam, Not set
Univ. Clinic Hosp, Bialystok, Bialystok, Not set
INTERCORE Medical Center, Bydgoszcz, Not set
NZOZ Medical Center KERmed, Bydgoszcz, Not set
Poradnia Kardiologiczna Jaroslaw Jurowiecki, Gdansk, Not set
Individual Specialist Medical Practice Krzysztof Cymerman, Gdynia, Not set
Pratia Katowice Medical Center, Katowice, Not set
Clinical Medical Research Sp. z o.o., Katowice, Not set
Specialistic Cardiology&Hypertension Out-patient Clin,Kielce, Kielce, Not set
Leszek Bryniarski Specialized Medical Cabinet, Krakow, Not set
Linden Sp. z o.o. sp.k., Kraków, Not set
Beata Miklaszewicz & Dariusz Dabrowski Cardiamed Sp. j., Legnica, Not set
SANTA FAMILIA Centrum Badan, Profilaktyki i Leczenia, Lodz, Not set
Individual Specialized Practice, Lodz, Not set
Lowickie Cardiology Center, Lowicz, Not set
Velocity Lublin, Lublin, Not set
Zanamed Medical Clinic Sp. z o.o., Lublin, Not set
Medeusz-Plus, Olsztyn, Not set
Medicome Sp. z o.o., Oswiecim, Not set
NZOZ HEUREKA, Piaseczno, Piaseczno, Not set
Non-Public Outpatient Clinic Neuro-Kard Ilkowski & Partners, Poznan, Not set
Aka-Med Centrum Sp. z o.o. S.K., Ruda Slaska, Not set
MEDYK Medical Center, Rzeszow, Not set
Lukmed Lukasz Wozniak, Siedlce, Not set
Velocity Skierniewice Sp. z o.o, Skierniewice, Not set
RCMed- Regionalne Centrum Medyczne, Sochaczew, Not set
NZOZ Procordis, Cardiology Research Center of Sopot, Sopot, Not set
Velocity Staszow, Staszow, Not set
FutureMeds Sp. z o.o., Warsaw, Not set
Balsammedica Sp. z o. o., Warszawa, Not set
4. Military Clinical Hospital with Polyclinic SP ZOZ, Wroclaw, Not set
Sedimed Sp. z o.o., Wroclaw, Not set
KO-MED Clinical Centers Zamosc, Zamosc, Not set
NZOZ Centrum Medyczne SERAFIN-MED Halina Serafin, Zarow, Not set
Spitalul Clinic De Urgenta Prof Dr Agrippa Ionescu, Balotesti, Not set
Spitalul Judetean de Urgenta Braila, Braila, Not set
S.C.Centrul Medical Unirea SRL, Brasov, Not set
S.C. Policlinica CCBR S.R.L., Bucharest, Not set
Emergency University Hospital, Bucharest, Bucharest, Not set
Clinica Medicala Data Plus SRL, Bucuresti, Not set
Spitalul Angiocare SRL, Cluj-Napoca, Not set
S.C.Centrul Medical Unirea S.R.L., Iasi, Not set
Sal Med Srl, Pitesti, Not set
Cmi Dr. Podoleanu Cristian, Targu Mures, Not set
Country Clinical Emergency Hospital, Targu-Mures, Targu-Mures, Not set
S.C Medicali's S.R.L, Timisoara, Not set
King AbdulAziz University Hospital, Jeddah, Not set
King Faisal Specialist Hospital and Research Center, Riyadh, Not set
King Abdulaziz Medical City, Riyadh, Not set
King Fahad Medical City, Riyadh, Not set
King Saud Medical City, Riyadh, Not set
Clinical Hospital Center Dr. Dragisa Misovic, Belgrade, Not set
Institute for Cardiovascular diseases Dedinje, Belgrade, Not set
University Clinical Center of Serbia, Belgrade, Not set
Clinical Hospital Center Zemun, Belgrade, Not set
University Clinical Center of Kragujevac, Kragujevac, Not set
Institute for Treatment and Rehabilitation, Niska Banja, Niska Banja, Not set
University Clinical Center Nis, Nis, Not set
General Hospital Pancevo, Pancevo, Not set
General Hospital Sveti Luka, Smederevo, Not set
Health Centre Zajecar, Zajecar, Not set
General Hospital Celje, Celje, Not set
University Hospital Golnik, Golnik, Not set
General Hospital Jesenice, Jesenice, Not set
University Medical Center Ljubljana, Ljubljana, Not set
General Hospital Murska Sobota, Murska Sobota, Not set
General Hospital Trbovlje, Trbovlje, Not set
Iatros International, Bloemfontein, Not set
Josha Research Centre, Bloemfontein, Not set
TREAD Research, Cape Town, Not set
Badenhorst, JCW, Centurion, Not set
Chris Hani Baragwanath Hospital: Cardiology Department, Johannesburg, Not set
Dr JM Engelbrecht, Somerset West, Not set
Clinical Projects Research, Worcester, Not set
Hospital Quiron. I.C.U., Barcelona, Not set
Hospital Universitario Virgen de la Arrixaca, El Palmar, Not set
Hospital General Universitario Gregorio Marañón, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital La Paz, Madrid, Not set
Hospital Virgen de la Victoria, Malaga, Not set
Hospital Virgen del Camino, Sanlúcar de Barrameda, Not set
Complexo Hospitalario Universitario De Santiago, Santiago de Compostela, Not set
Hospital Clínico de Valencia, Valencia, Not set
Hospital General Universitario de Valencia, Valencia, Not set
Hospital Politècnic La Fe, Valencia, Not set
Hospital Virgen de las Montañas, Villamartin, Villamartin, Cardiz, Not set
E-Da Hospital, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
Taichung Veterans General Hospital, Taichung, Not set
Taipei Medical University Hospital, Taipei City, Not set
National Taiwan University Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Cheng Hsin General Hospital, Taipei, Not set
Chang Gung Memorial Hospital(Linkou), Taoyuan County, Not set
Çukurova Ü. Tip Fak., Balcali Hastanesi, Kardiyoloji, Adana, Not set
Afyon Kocatepe University Medical Faculty, Afyon, Not set
Etlik City Hospital, Ankara, Not set
Firat University Hospital, Elazıg, Not set
Ataturk Universitesi Tip Fakultesi, Erzurum, Not set
Osmangazi Uni Medical Faculty, Eskisehir, Not set
Gaziantep University Medical Faculty Sahinbey Educational Research Hospital, Gaziantep, Not set
Siyami Ersek Gogus Kalp ve Damar Cerrahisi Hastanesi, Istanbul, Not set
Marmara University Pendik Training and Research Hospital, Istanbul, Not set
Medical Park Pendik Hospital, Istanbul, Not set
Kutahya Health Science University, Kutahya, Not set
Inonu Universitesi Tip Fakultesi Gogus Hastaliklari ABD, Malatya, Not set
Mersin University Medical Faculty, Mersin, Not set
KTU Tip Fakultesi Farabi Hastanesi, Trabzon, Not set
Barnet Hospital, Barnet, Not set
Southmead Hospital, Bristol, Not set
Royal Devon and Exeter Hospital, Wonford, Exeter, Not set
Calderdale Royal Hospital, Halifax, Not set
St Bartholomew's Hospital, London, Not set
The Royal Oldham Hospital, Oldham, Not set
Northern General Hospital, Sheffield, Not set
Royal Cornwall Hospital, Truro, Not set
York and Scarborough Teaching Hospitals NHS Foundation Trust York Hospital, York, Not set
Bach Mai hospital, Hanoi, Not set
Cho Ray Hospital, Ho Chi Minh City, Not set
Nguyen Tri Phuong Hospital, Ho Chi Minh City, Not set
Tam Duc Heart Hospital, Ho Chi Minh, Not set
Thong Nhat Hospital HCMC, Ho Chi Minh, Not set
Conditions: Heart Failure
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease
Recruiting
The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease.
The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants with apolipoprotein L1 (APOL1)-mediated proteinuric kidney disease. Read Less
Gender:
ALL
Ages:
Between 10 years and 65 years
Trial Updated:
08/21/2025
Locations: Alabama Kidney Research, Alabaster, Alabama +313 locations
Alabama Kidney Research, Alabaster, Alabama
EmVenio Research - Mobile Unit - Birmingham, Birmingham, Alabama
Cardiology, P.C., Birmingham, Alabama
Children's Hospital of Alabama, Birmingham, Alabama
The Kirklin Clinic - Nephrology, Birmingham, Alabama
Nephrology Associates, Fairhope, Alabama
Heart Center Research LLC, Huntsville, Alabama
Nephrology Consultants, LLC, Huntsville, Alabama
Renal Associates of Alabama, LLC, Montgomery, Alabama
Phoenix Children's Hospital, Inc. - Nephrology, Phoenix, Arizona
CHI St. Vincent Heart Clinic Arkansas- Cardiology and Medicine Clinic - Little Rock, Little Rock, Arkansas
UAMS Medical Center - Pulmonology, Little Rock, Arkansas
The Medical Research Group - Saint Agnes Medical Center, Fresno, California
Amicis Research Center - Balboa, Granada Hills, California
Kidney Care Center of North Valley, Granada Hills, California
Eastside Clinical Research Associates, Los Angeles, California
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
Cedars-Sinai Medical Center, Los Angeles, California
UCLA Division of Nephrology, Los Angeles, California
UCI Center for Clinical Research, Orange, California
Kaiser Permanente Sacramento Medical Center, Sacramento, California
Helen Diller Medical Center at Parnassus Heights, San Francisco, California
UCLA Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California
Kidney and Hypertension Center, Victorville, California
Greater Hartford Nephrology, Bloomfield, Connecticut
Nephrology & Hypertension Associates, PC, Middlebury, Connecticut
Yale University - Yale Nephrology Clinical Research Clinic, New Haven, Connecticut
Children's National Hospital - Nephrology, Washington, District of Columbia
The George Washington University - GW Medical Faculty Associates, Washington, District of Columbia
Veterans Affairs Medical Center - Washington D.C, Washington, District of Columbia
Bay Pines Foundation, Bay Pines, Florida
Nova Clinical Research, LLC - Bradenton - 59th St, Bradenton, Florida
Clinical Research of Brandon, LLC, Brandon, Florida
AMR-Miami, Coral Gables, Florida
Horizon Research Group - Coral Gables, Coral Gables, Florida
South Florida Nephrology Research, Coral Springs, Florida
Delray Physician Care Center, Delray Beach, Florida
North Florida/South Georgia Veterans Health System, Gainesville, Florida
Shands Hospital - Nephrology, Gainesville, Florida
Velocity Clinical Research - Hallandale Beach, Hallandale Beach, Florida
Qway Research, Hialeah, Florida
Elixia Pines, Hollywood, Florida
UF Health Cardiovascular Center - Jacksonville, Jacksonville, Florida
South Florida Research Institute, Lauderdale Lakes, Florida
South Florida Research, Miami Springs, Florida
Total Research Group, LLC, Miami, Florida
MedBio Trials, Miami, Florida
Cordova Research Institute, Miami, Florida
CTR Oakwater, LLC, Orlando, Florida
Synexus Clinical Research - Orlando, Orlando, Florida
Omega Research Orlando, LLC - Mercy Dr, Orlando, Florida
Infigo Clinical Research, Sanford, Florida
Genesis Clinical Research, Tampa, Florida
Elixia Tampa, Tampa, Florida
American Clinical Trials LLC - Acworth, Acworth, Georgia
Kaiser Permanente Georgia, Atlanta, Georgia
Emory School of Medicine - Renal Division, Atlanta, Georgia
Advanced Clinical Research of Atlanta, Atlanta, Georgia
Morehouse School of Medicine, Grady Memorial Hospital, Atlanta, Georgia
Emory Childrens Center - Nephrology, Atlanta, Georgia
Synexus Clinical Research - Atlanta (DRS), Atlanta, Georgia
Fides Clinical Research, Atlanta, Georgia
Augusta University Medical College of Georgia - Adult Sickle Cell Clinic, Augusta, Georgia
Coastal Medical Research, Brunswick, Georgia
Randomize Now - College Park, College Park, Georgia
Clincept - Veterans Pkwy., Columbus, Georgia
Renal Associates, Columbus, Georgia
Georgia Nephrology - Decatur, Decatur, Georgia
Atlanta VA Healthcare System, Decatur, Georgia
American Clinical Trials LLC - Douglasville, Douglasville, Georgia
Southeast Kidney Associates, East Point, Georgia
Javara Inc./Privia Medical Group - Fayetteville, GA, Fayetteville, Georgia
Georgia Nephrology - Lawrenceville - Billing Office, Lawrenceville, Georgia
Javara Inc./Privia Medical Group - Savannah, GA, Savannah, Georgia
Inova Clinical Trials and Research Center, Tyrone, Georgia
Rophe Adult and Pediatric Medicine, Union City, Georgia
Synexus Clinical Research - Chicago (DRS), Chicago, Illinois
EmVenio Research - Chicago, Chicago, Illinois
Ann & Robert H. Lurie Children's Hospital of Chicago - Nephrology, Chicago, Illinois
Northwestern Medical Group, Chicago, Illinois
UChicago Medicine - Comer Children's Hospital, Chicago, Illinois
NANI Research LLC - Evergreen Park IL, Evergreen Park, Illinois
Edward Hines Jr VA Hospital, Hines, Illinois
Essential Concepts Research Solutions, Palos Hills, Illinois
NANI Research LLC - Fort Wayne IN, Fort Wayne, Indiana
IU School of Medicine - Nephrology, Indianapolis, Indiana
Nephrology Physicians, LLC, Mishawaka, Indiana
University of Iowa Health Care Medical Center- Nephrology, Iowa City, Iowa
Clinical & Translational Science Unit (CTSU) - Nephrology, Kansas City, Kansas
Premier Clinical Research, Overland Park, Kansas
Renal Associates of Baton Rouge, Baton Rouge, Louisiana
LCMC Health, Metairie, Louisiana
Barnum Medical Research - Bienville St, Natchitoches, Louisiana
Louisiana Clinical and Translational Science (LA CaTS) Center, New Orleans, Louisiana
University Medical Center - New Orleans - Nephrology, New Orleans, Louisiana
Ochsner Medical Center - New Orleans, New Orleans, Louisiana
Northwest Louisiana Nephrology, LLC, Shreveport, Louisiana
Louisiana State University Health Shreveport, Shreveport, Louisiana
Monroe Research, LLC, West Monroe, Louisiana
Javara Inc./Privia Medical Group - Annapolis, MD, Annapolis, Maryland
University of Maryland Medical Center - General Clinical Research Center, Baltimore, Maryland
The Johns Hopkins University - Johns Hopkins Hospital - Nephrology, Baltimore, Maryland
Mid-Atlantic Permanente Research Institute, Gaithersburg, Maryland
Patient First Clinical Trials, Lutherville, Maryland
MD Medical Research, Oxon Hill, Maryland
Javara Inc./Privia Medical Group - Silver Spring, MD - Columbia Pike, Silver Spring, Maryland
Tufts Medical Center, Boston, Massachusetts
Boston Medical Center, Boston, Massachusetts
Beth Israel Deaconess Medical Center - Nephrology, Boston, Massachusetts
Whittier Street Health Center, Roxbury, Massachusetts
Renal and Transplant Associates of New England, PC, Springfield, Massachusetts
Kidney Care and Transplant Services of New England - West Springfield, West Springfield, Massachusetts
A. Alfred Taubman Health Care Center - Nephrology Clinic at Taubman Center, Ann Arbor, Michigan
Henry Ford Health System - Nephrology, Detroit, Michigan
Quest Research Institute, Farmington Hills, Michigan
AA Medical Research Center, Flint, Michigan
Sparrow Clinical Research Institute, Lansing, Michigan
St. Clair Nephrology Research, Roseville, Michigan
Center for Advanced Kidney Research, Saint Clair Shores, Michigan
InterMed Consultants - Edina Clinic, Edina, Minnesota
Minneapolis VA Healthcare System, Minneapolis, Minnesota
Nephrology Associates, P.C. - Columbus, Columbus, Mississippi
Prime Health and Wellness, Fayette, Mississippi
UMMC Grenada Hospital, Grenada, Mississippi
G.V. (Sonny) Montgomery VAMC, Jackson, Mississippi
Olive Branch Family Medical Center, Olive Branch, Mississippi
SKY Integrative Medical Center, Ridgeland, Mississippi
Nephrology and Hypertension Associates - Tupelo, Tupelo, Mississippi
Center for Specialized Medicine - Nephrology, Saint Louis, Missouri
Barnes-Jewish Center for Outpatient Health, Saint Louis, Missouri
St. Louis Children's Hospital - Nephrology, Saint Louis, Missouri
St. Louis Heart and Vascular, P.C., Saint Louis, Missouri
Nevada Kidney Disease and Hypertension Centers, Las Vegas, Nevada
DaVita Kidney Care - Las Vegas, Las Vegas, Nevada
CUH - Sheridan Pavilion - Three Cooper Plaza, Camden, New Jersey
Hackensack University Medical Center, Hackensack, New Jersey
Bioluminux Clinical Research New Jersey, Hamilton, New Jersey
Jersey Shore University Medical Center, Neptune, New Jersey
Rutgers Doctors Office Center, Newark, New Jersey
New Mexico VA Healthcare System, Albuquerque, New Mexico
Renal Medicine Associates, Albuquerque, New Mexico
Kidney Medical Associates, PLLC, Bronx, New York
Montefiore Einstein - Albert Einstein College of Medicine, Bronx, New York
Montefiore Einstein Hospital - Moses Campus, Bronx, New York
James J. Peters VA Medical Center, Bronx, New York
Kings County Hospital, Brooklyn, New York
SUNY Downstate Health Sciences University, Brooklyn, New York
Clindove Research LLC, Brooklyn, New York
New York Presbyterian Queens, Flushing, New York
Zucker School of Medicine, Great Neck, New York
Scott Research, Inc., Laurelton, New York
VA New York Harbor Healthcare System, New York, New York
Grossman School of Medicine, New York, New York
Synexus Clinical Research - New York (DRS), New York, New York
The Rogosin Kidney Center, New York, New York
Icahn School of Medicine at Mount Sinai - Nephrology, New York, New York
General Nephrology Clinic - New York City, New York, New York
NYC Health + Hospital/Harlem, New York, New York
North Carolina Nephrology P.A. - Cary, Cary, North Carolina
UNC Clinical and Translational Research Center, Chapel Hill, North Carolina
Metrolina Nephrology Associates - Freedom Dr, Charlotte, North Carolina
Duke University Hospital - Children's Health Center, Durham, North Carolina
Eastern Nephrology Associates - Greenville Office, Greenville, North Carolina
Eastern Nephrology Associates - Jacksonville Office, Jacksonville, North Carolina
Eastern Nephrology Associates - Kinston Office, Kinston, North Carolina
Eastern Nephrology Associates - New Bern Office, New Bern, North Carolina
Eastern Nephrology Associates - Wilmington Office, Wilmington, North Carolina
Brookview Hills Research Associates, Winston-Salem, North Carolina
UC - DCI McMillan Research Unit, Cincinnati, Ohio
Cincinnati VA Medical Center, Cincinnati, Ohio
Louis Stokes Cleveland VA medical Center, Cleveland, Ohio
UH Cleveland Medical Center - Nephrology, Cleveland, Ohio
Cleveland Clinic - Main Campus, Cleveland, Ohio
Ohio State University - Wexner Medical Center - Nephrology Clinical Trials Unit, Columbus, Ohio
Jefferson Health - 33 South 9th Street, Philadelphia, Pennsylvania
Lewis Katz School of Medicine at Temple University - Section of Nephrology, Philadelphia, Pennsylvania
Jefferson Einstein Philadelphia Hospital - Nephrology, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh - Nephrology, Pittsburgh, Pennsylvania
Lifespan Clinical Research Center, East Providence, Rhode Island
Pharmacorp Clinical Trials, Inc, Charleston, South Carolina
Medical University of South Carolina - Pulmonology, Charleston, South Carolina
Columbia Nephrology Associates, PA, Columbia, South Carolina
Carolina Nephrology, PA, Spartanburg, South Carolina
Southeast Renal Research Institute, Chattanooga, Tennessee
Le Bonheur Children's Hospital - Outpatient Clinic, Memphis, Tennessee
CNS Healthcare - Memphis, Memphis, Tennessee
Nashville General Hospital - Meharry Medical College - Nephrology, Nashville, Tennessee
Nashville VA Medical Center, Nashville, Tennessee
Nephrology Clinical Trials Center, Nashville, Tennessee
Dallas Renal Group - Mansfield, Arlington, Texas
Arlington Nephrology, Arlington, Texas
Baylor Scott and White Research Institute - Nephrology, Dallas, Texas
Dallas Renal Group- Dallas, Dallas, Texas
Zenos Clinical Research, Dallas, Texas
Nephrotex Research Group, Dallas, Texas
Dallas Renal Group - Liberty Dallas Dialysis Center, Dallas, Texas
Dallas Nephrology Associates - Dallas Landry Office, Dallas, Texas
Southwest Family Medicine Associates (SFMA) - Dallas, Dallas, Texas
UTSW Medical Center - Nephrology, Dallas, Texas
Davita Clinical Research - El Paso, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Prolato Clinical Research Center - Kirby Dr, Houston, Texas
Ronald Ralph MD PA, Houston, Texas
Houston Medical Research Institute, LLC, Houston, Texas
Clinical Research Strategies - Romano North Main Office, Houston, Texas
Frenova-Southwest Houston, Houston, Texas
NTKDA Lewisville, Lewisville, Texas
Prime Clinical Research Inc - Lewisville, Lewisville, Texas
Texas Tech University Health Sciences Center, Lubbock, Texas
Prime Clinical Research - Mansfield - Regency Parkway, Mansfield, Texas
San Antonio Kidney Disease Center Physicians Group - Medical Center, San Antonio, Texas
University of Texas Health Science Center - Nephrology, San Antonio, Texas
San Antonio Kidney Disease Center Physicians Group - Westover Hills, San Antonio, Texas
Kidney Specialists of N Houston, PLLC, Shenandoah, Texas
Renal Research of Montgomery County, PLLC, The Woodlands, Texas
Tranquil Clinical Research, Webster, Texas
UVA Health - Nephrology Clinical Research Center, Charlottesville, Virginia
Tidewater Kidney Specialists - Church St., Norfolk, Virginia
York Clinical Research, LLC, Norfolk, Virginia
McGuire Research Institute, Inc. (151), Richmond, Virginia
Virginia Commonwealth University - Division of Nephrology, Richmond, Virginia
Nephrology Associates of Tidewater, LTD, Virginia Beach, Virginia
UW Medical Center - Montlake - Nephrology, Seattle, Washington
Medical College of Wisconsin - Pulmonology, Milwaukee, Wisconsin
Milwaukee Nephrologists - Wauwatosa, Wauwatosa, Wisconsin
Universite Catholique de Louvain - Pulmonology, Woluwe-Saint-Lambert, Brussels
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg - Pulmonology, Leuven, Not set
Centro de Pesquisa Clinica do Coracao, Aracaju, Not set
Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, Not set
Faculdade de Medicina de Botucatu - CKD and Hypertension Department, Botucatu, Not set
Faculdade de Medicina de Botucatu - Kidney Transplantation Department, Botucatu, Not set
IPECC - Instituto de Pesquisa Clinica de Campinas, Campinas, Not set
Instituto Pro-Renal, Curitiba, Not set
PUC Trials - Unidade Epicenter, Curitiba, Not set
Instituto de Ensino e Pesquisa Clinica do Ceara, Fortaleza, Not set
Walter Cantídio University Hospital, Fortaleza, Not set
Federal University of Goiás (UFG), Goiania, Not set
Cmip-Centro Mineiro de Pesquisa Ltda, Juiz de Fora, Not set
Galileo Medical Research Ltda, Juiz De Fora, Not set
ICM - Instituto do Coracao de Marilia, Marilia, Not set
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Monte Alegre, Not set
Dom Vicente Scherer Hospital, Porto Alegre, Not set
Hospital de Clínicas de Porto Alegre - Nephrology, Porto Alegre, Not set
Centro de Pesquisa Clinica Professor Salomao Kelner, Recife, Not set
Hospital São Lucas, Rio de Janeiro, Not set
Comlexo Hospitalar Universitário Professor Edgard Santos, Salvador, Not set
CSB Group of Nephrology Brazil, Salvador, Not set
Hospital Ana Nery/SESAB, Salvador, Not set
Praxis Pesquisa Medica, Santo Andre, Not set
Hospital Nove de Julho - Nephrology, Sao Paulo, Not set
Irmandade Da Santa Casa De Misericordia De Sao Paulo, Sao Paulo, Not set
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Not set
Hospital das Clínicas da Faculdade de Medicina - Laboratório de Nefrologia Celular, Genética e Molecular, São Paulo, Not set
Hospital do Rim - Fundação Oswaldo Ramos, São Paulo, Not set
Recherche GCP Research, Montreal, Not set
Women's College Hospital, Toronto, Not set
Clinica de La Costa S.A.S, Atlántico, Not set
Solano & Terront Servicios Medicos SAS - Unidad Integral de Endocrinologia - UNIENDO, Bogota, Not set
Fundación Valle Del Lili, Cali, Not set
Centro Cardiovascular Aristides Sotomayor Santa Lucía SAS IPS, Cartagena, Not set
Mediservis del Tolima IPS S.A.S., Ibague, Not set
Promotora Medica Las Americas S.A. - Clinica Las Americas, Medellin, Not set
Fundación Hospitalaria San Vicente de Paul, Medellín, Not set
Hopital Henri Mondor - Nephrology, Créteil, Not set
Hospital Nord Michallon - Nephrology, Grenoble, Not set
Bicetre Hospital, Le Kremlin Bicêtre, Not set
CHU Dupuytren 2 - Néphrologie, dialyse, transplantations, Limoges, Not set
Hôpital de la Conception, Marseille, Not set
Ambroise Paré Hospital, Paris, Not set
Hopital Necker Enfants Malades - Nephrology, Paris, Not set
Hopital Tenon, Paris, Not set
Université Paris-Descartes / Hôpital Européen Georges Pompidou, Paris, Not set
CHU de Guadeloupe, Pointe-à-Pitre Cedex, Not set
AURA Nord, Saint-Ouen, Not set
Hopital de Rangueil, Toulouse, Not set
University of Ghana Medical School - Nephrology, Accra, Not set
The Bank Hospital, Cantonments, Not set
Komfo Anokye Teaching Hospital - Nephrology, Kumasi, Not set
Amsterdam UMC - Amsterdam Public Health Research Institute, Amsterdam, Not set
University of Nigeria Teaching Hospital, Enugu, Not set
University College Hospital, Ibadan, Not set
Lagos University Teaching Hospital, Idi-Araba, Not set
Lagos State University Teaching Hospital, Ikeja, Not set
Nigerian Institute of Medical Research, Lagos, Not set
Unidade Local de Saude Amadora/Sintra, E.P.E., Amadora, Not set
Hospital Curry Cabral - Serviço de Nefrologia, Lisboa, Not set
Unidade Local de Saúde de Santa Maria, E.P.E. - Nephrology, Lisboa, Not set
Unidade Local de Saúde de Loures-Odivelas, E.P.E., Loures, Not set
FDI Clinical Research, Mayaguez, Not set
University of Puerto Rico, Rio Piedras, Not set
GCM Medical Group, PSC, San Juan, Not set
Hospital Clinic de Barcelona - Nephrology, Barcelona, Not set
Hospital Universitari Vall d´Hebron - Servicio de Pediatria, Barcelona, Not set
Reina Sofia University Hospital - Nephrology, Córdoba, Not set
Hospital Universitario 12 de Octubre - Nephrology, Madrid, Not set
Hospital Universitario Virgen Macarena, Seville, Not set
Mid and South Essex Hospitals NHS Trust, Basildon, Not set
Synexus Clinical Research - Glasgow (DRS), Bellshill, Not set
FutureMeds Birmingham, Birmingham, Not set
Queen Elizabeth Hospital Birmingham, Birmingham, Not set
Synexus Clinical Research - Midlands (DRS), Birmingham, Not set
Epsom and St Helier University Hospitals NHS Trust, Carshalton, Not set
Leicester General Hospital, Leicester, Not set
Great Ormond Street Hospital for Children, London, Not set
Guy's Hospital - Endocrinology, London, Not set
King's College Hospital - Pulmonology, London, Not set
Royal Free Hospital - Nephrology, London, Not set
St George's Hospital London - Nephrology, London, Not set
St Pancras Clinical Research, London, Not set
The Royal London Hospital - Nephrology, London, Not set
Manchester Royal Infirmary - Endocrinology, Manchester, Not set
Synexus Clinical Research - NW Consortium Manchester (DRS), Manchester, Not set
Wythenshawe Hospital - Medicines Evaluation Unit, Manchester, Not set
Nottingham University Hospitals - Children's Clinical Research Facility - Pulmonology, Nottingham, Not set
Conditions: Proteinuric Kidney Disease
A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib
Recruiting
This is a Phase 3, 2-arm, randomized, open-label, global, multicenter study comparing the efficacy of ripretinib to sunitinib in participants with GIST who progressed on first-line treatment with imatinib, harbor co-occurring KIT exons 11+17/18 mutations, and are without KIT exon 9, 13, or 14 mutations. Upon disease progression as determined by an independent radiologic review, participants randomized to sunitinib will be given the option to either crossover to receive ripretinib 150 mg QD or di... Read More
This is a Phase 3, 2-arm, randomized, open-label, global, multicenter study comparing the efficacy of ripretinib to sunitinib in participants with GIST who progressed on first-line treatment with imatinib, harbor co-occurring KIT exons 11+17/18 mutations, and are without KIT exon 9, 13, or 14 mutations. Upon disease progression as determined by an independent radiologic review, participants randomized to sunitinib will be given the option to either crossover to receive ripretinib 150 mg QD or discontinue sunitinib. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: UC San Diego Moores Cancer Center, La Jolla, California +64 locations
UC San Diego Moores Cancer Center, La Jolla, California
Yale University, New Haven, Connecticut
Mayo Clinic Florida, Jacksonville, Florida
Sylvester Comprehensive Cancer Center, Miami, Florida
Moffitt Cancer Center, Tampa, Florida
Johns Hopkins Hospital, Baltimore, Maryland
Boston Medical Center, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
M Health Fairview University of Minnesota Medical Center, Minneapolis, Minnesota
Mayo Clinic, Rochester, Minnesota
Memorial Sloan Kettering Cancer Center, New York, New York
Northwell Health Cancer Institute/ R.J. Zuckerberg Cancer Center, New York, New York
Cleveland Clinic, Cleveland, Ohio
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio
OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma
Oregon Health & Science University, Portland, Oregon
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
The University of Texas MD Anderson Cancer Center, Houston, Texas
Fred Hutchinson Cancer Center, Seattle, Washington
Prince of Wales Hospital, Randwick, New South Wales
Alfred Health, Melbourne, Victoria
CEPEN - Centro de Pesquisa e Ensino em Saude de Santa Catarina, Florianópolis, Santa Catarina
Hospital de Cancer de Barretos - Fundacao Pio XII, Barretos, Sao Paulo
Hospital Sirio-Libanes, São Paulo, Sao Paulo
Hospital 9 de Julho, São Paulo, SP
INCA - Instituto Nacional de Cancer, Rio De Janeiro, Not set
AC Camargo Câncer Center, São Paulo, Not set
Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta
Juravinski Cancer Centre, Hamilton, Ontario
University Health Network, Princess Margaret Cancer Centre, Toronto, Ontario
McGill University Health Centre, Montréal, Quebec
Clínica San Carlos De Apoquindo Red Salud UC Christus, Las Condes, RM
Centro de Oncología de Precisión, Santiago, RM
CHU Dijon, Dijon Cedex, Bourgogone
Centre Eugène Marquis, Rennes, Ille et Vilaine
Institut Bergonié, Bordeaux, Not set
Centre Léon Bérard, Lyon, Not set
Institut Gustave Roussy, Villejuif, Not set
Helios Klinikum Berlin-Buch, Berlin, Not set
University Hospital Essen (Universitätsklinikum Essen), Essen, Not set
Universitares Krebszentrum Leipzig, Leipzig, Not set
Istituto Nazionale Tumori IRCCS Fondazione "G Pascale", Naples, Napoli
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi, Bologna, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Not set
Istituto Oncologico Veneto-IOV IRCCS, Padova, Not set
U.O.C. Oncologia Medica, Palermo, Not set
Università Campus Bio-Medico di Roma, Roma, Not set
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
UMC Groningen, Groningen, Not set
LUMC, Leiden, Not set
Oslo University Hospital, Oslo, Not set
Narodowy Instytut Onkologii Im . Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Warsaw, Warszawa
Complejo Hospitalario Universitario de Vigo - Hospital Alvaro Cunqueiro, Vigo, Pontevedra
Hospital Universitario Vall d'Hebron, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Instituto Valenciano de Oncologia - IVO, Valencia, Not set
China Medical University Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
The Royal Marsden Hospital NHS Foundation Trust, London, Greater London
St. James University Hospital, Leeds, West Yorkshire
Conditions: GIST
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Recruiting
To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis.
To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: OM Research LLC, Lancaster, California +88 locations
OM Research LLC, Lancaster, California
SCPMG/Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
Cedar Sinai Medical Center, Los Angeles, California
California Liver Research Institute, Pasadena, California
University of California, Davis Medical Center, Sacramento, California
California Pacific Medical Center - Sutter Pacific Medical Foundation, San Francisco, California
Connie Frank Transplant Center at UCSF, San Francisco, California
Covenant Metabolic Specialists, LLC, Fort Myers, Florida
Schiff Center for Liver Diseases/University of Miami, Miami, Florida
Covenant Metabolic Specialists, LLC, Sarasota, Florida
Florida Research Institute, Tampa, Florida
Piedmont Atlanta Hospital / Piedmont Transplant Institute, Atlanta, Georgia
University of Chicago Medical Center, Chicago, Illinois
University Of Iowa Hospitals And Clinics, Iowa City, Iowa
University of Louisville, Clinical Trials Unit, Louisville, Kentucky
Ochsner Clinic Foundation, Jefferson, Louisiana
University Health System - East Jefferson General Hospital Campus, New Orleans, Louisiana
Mercy Medical Center, Baltimore, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Beth Israel Deaconess Medical Center, Boston, Massachusetts
Henry Ford Medical Center - Columbus, Detroit, Michigan
Northwell Health Center for Liver Disease and Transplantation, Manhasset, New York
NYU Langone Health, New York, New York
Mount Sinai, New York, New York
Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
University Hosptials Cleveland Medical Center, Cleveland, Ohio
Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania
Thomas Jefferson University, Philadelphia, Pennsylvania
UPMC Center for Liver Diseases, Pittsburgh, Pennsylvania
Gastro One, Cordova, Tennessee
The Liver Institute at Methodist Dallas Medical Center, Dallas, Texas
University of Texas Southwestern Medical Center, Professional Office Building One, Dallas, Texas
Pinnacle Clinical Research, PLLC, San Antonio, Texas
MedStar Health Research Institute / MedStar Georgetown Transplant Institute at Fairfax, Fairfax, Virginia
Maryview Hospital LLC d/b/a Bon Secours Liver Institute of Hampton Roads, Newport News, Virginia
VCU Health Clinical Research Services Unit (CRSU), Richmond, Virginia
Liver Institute Northwest, Seattle, Washington
Hospital Italiano de Buenos Aires, Buenos Aires, Not set
Consultorios Médicos Dr. Doreski - PPDS, Ciudad Autonoma de Buenos Aires, Not set
Buenos Aires Mácula, Ciudad Autónoma de Buenos Aires, Not set
Centro de Investigación y Prevención Cardiovascular, Ciudad Autónoma de Buenos Aires, Not set
AES - AS - Glenny Corp. S.A. Buenos Aires, Ciudad Autónoma de Buenos Aires, Not set
CINME S.A. - Centro de Investigaciones Metabólicas, Recoleta, Not set
Flinders Medical Center, Adelaide, South Australia
Monash Health, Monash Medical Centre, Clayton, Victoria
Alfred Hospital, Melbourne, Victoria
Klinikum Wels-Grieskirchen GmbH - Standort Wels, Wels, Not set
Krankenhaus der Barmherzigen Brüder, Wien, Not set
GI Research Institute Foundation, Vancouver, Not set
Centro de Investigación y Prevención Cardiovascular, La Serena, Not set
Pontificia Universidad Católica de Chile, Santiago, Not set
BIOCINETIC Ltda, Santiago, Not set
Clinical Research Chile SpA - PPDS, Valdivia, Not set
RESEARCH Site s.r.o, Plzen, Not set
Hospices Civils de Lyon (HCL) - Hopital de la Croix-Rousse, Lyon, Not set
CHU-Montpellier-Hopital St Eloi, Montipellier, Not set
Somogy Varmegyei Kaposi Mor Oktato Korhaz, Kaposvár, Not set
Pusan National University Hospital, Busan, Not set
Kyungpook National University Hospital, Daegu, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Seongnam, Not set
Asan Medical Center, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Consultorio Medico - Distrito Federal, Ciudad de Mexico, Not set
Clinica de Higado y Gastroenterologia Integral, S.C., Cuernavaca, Not set
Centro De Investigacion Y Gastroenterogia, S.C., Mexico, Not set
ID Clinic Arkadiusz Pisula, Myslowice, Not set
PlanetMed SP. z. o. o, Wroclaw, Not set
Institutul Clinic Fundeni, Bucharest, Not set
Kyungpook National University Hospital, Singapore, Not set
Hospital del Mar, Barcelona, Not set
Hospital Universitario Vall d'Hebron-VIHR, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
C.H. Regional Reina Sofia - PPDS, Cordoba, Not set
Hospital Universitario Virgen de la Victoria, Malaga, Not set
Universitätsspital Bern, Bern, Not set
Universitätsspital Zürich, Zurich, Not set
Adana City Training and Research Hospital, Adana, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Gaziantep University Medical Faculty Sahinbey Research and Practice Hospital, Gaziantep, Not set
Uludag University Medical Faculty, Gorukle, Not set
Ege University, Izmir, Not set
Katip Celebi University, Karabağlar, Not set
Kocaeli University Medical Faculty Hospital, Kocaeli, Not set
Mersin Universitesi Tip Fakultesi Hastanesi, Mersin, Not set
Marmara University Pendik Training and Research Hospital, Pendik, Not set
Rize Recep Tayyip Erdogan University Training and Research Hospital, Rize Merkez, Not set
Conditions: Primary Biliary Cholangitis
Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer
Recruiting
The primary objective of this study is to compare the effect of zimberelimab (ZIM) and domvanalimab (DOM) in combination with chemotherapy relative to pembrolizumab (PEMBRO) in combination with chemotherapy on overall survival (OS) in patients with untreated metastatic non-small cell lung cancer with no actionable genomic alteration.
The primary objective of this study is to compare the effect of zimberelimab (ZIM) and domvanalimab (DOM) in combination with chemotherapy relative to pembrolizumab (PEMBRO) in combination with chemotherapy on overall survival (OS) in patients with untreated metastatic non-small cell lung cancer with no actionable genomic alteration. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: Palo Verde Hematology Oncology Ltd, Glendale, Arizona +226 locations
Palo Verde Hematology Oncology Ltd, Glendale, Arizona
California Cancer Associates for Research and Excellence, San Marcos, California
Texas Oncology, Santa Barbara, California
Innovative Clinical Research Institute, Whittier, California
Eastern CT Hematology and Oncology Associates, Norwich, Connecticut
George Washington Medical Faculty Associates, Washington, District of Columbia
Lake City Cancer Care, Lake City, Florida
Florida Cancer Specialists, Sarasota, Florida
Moffitt Cancer Center, Tampa, Florida
Peachtree Hematology Oncology Consultants, Atlanta, Georgia
Illinois Cancer Care, Peoria, Illinois
Messino Cancer Centers, Asheville, North Carolina
Oncology Hematology Care, Inc., Cincinnati, Ohio
Hematology & Oncology Associates, Eugene, Oregon
AHN Allegheny General Hospital, Pittsburgh, Pennsylvania
Arlington Cancer Center, Arlington, Texas
Texas Oncology - Austin, Austin, Texas
Texas Oncology, Dallas, Texas
Texas Oncology- Denison, Sherman, Texas
US Oncology Investigational Products Center (IPC), Arlington, Virginia
Oncology and Hematology Associates of Southwest Virginia, Inc, Blacksburg, Virginia
Northwest Cancer Specialists, PC, Vancouver, Washington
Investigaciones CORI S.R.L., Capital, Not set
Centro Médico Privado Centro de Especialidades Médicas Ambulatorias e Investigación Clínica, Cardoba, Not set
Centro Medico Barrio Parque, Ciudad Autanoma Buenos Aires, Not set
Sanatorio Allende, Cordoba, Not set
Sanatorio Britanico de Rosario, Rosario, Not set
Sanatorio Parque de Rosario, Rosario, Not set
Hospital Provincial del Centenario, Rosario, Not set
Instituto Medico de la Fundacion Estudios Clinicos, Rosario, Not set
CAIPO - Centro para la Atención Integral del Paciente Oncológico, San Miguel de Tucumán, Not set
Clínica Viedma, Viedma, Not set
Klinikum Klagenfurt am Woerthersee, Klagenfurt Am Woerthersee, Not set
Ordensklinikum Linz GmbH, Elisabethinen, Linz, Not set
Klinikum Wels-Grieskirchen, Wels, Not set
Krankenhaus Nord - Klinik Floridsdorf, Wien, Not set
Algemeen Ziekenhuis Sint-Lucas, Aalst, Not set
Grand Hopital de Charleroi asbl (GHdC), Charleroi, Not set
AZ Sint-Maarten, Mechelen, Not set
CHU UCL Namur / Site Sainte Elisabeth, Namur, Not set
Cenantron Centro Avançado de Tratamento Oncologico Ltda, Belo Horizonte, Not set
Hospital Evangelico de Cachoeiro de Itapemirim, Cachoeiro De Itapemirim, Not set
Fundacao Universidade De Caxias Do Sul - FUCS/RS, Caxias Do Sul, Not set
Instituto do Câncer do Ceará - ICC, Fortaleza, Not set
Oncosite - Centro de Pesquisa Clinica em Oncologia LTDA, Ijui, Not set
Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set
Hospital de Clínicas de Porto Alegre, Porto Alegre, Not set
Hospital São Lucas da PUCRS, Porto Alegre, Not set
Hospital Ana Nery Santa Cruz do Sul, Santa Cruz Do Sul, Not set
Centro Des Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho, Sao Paolo, Not set
Instituto Brasiliero de Controle do Cancer IBCC, Sao Paulo, Not set
Centre Integre de sante et de services sociaux de la Monteregie Centre, Greenfield Park, Not set
Moncton Hospital, Moncton, Not set
CISSS des Laurentides, Quebec, Not set
Centre de santé et services sociaux de Rimouski-Neigette, Rimouski, Not set
BC Cancer - Victoria, Victoria, Not set
Clinica Alemana de Santiago, Las Condes, Not set
Orlandioncologia, Providencia, Not set
Oncovida- Santiago, Providencia, Not set
Clinica Puerto Montt, Puerto Montt, Not set
Biocinetic, Santiago, Not set
James Lind Centro de Investigacion del Cancer, Temuco, Not set
Oncocentro APYS, Vina del Mar, Not set
West China Hospital Sichuan University, Chengdu, Not set
Chongqing University Cancer Hospital, Chongqing, Not set
Deyang People's Hospital, Deyang, Not set
Fujian Cancer Hospital, Fuzhou, Not set
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Not set
Guangzhou First People's Hospital, Guangzhou, Not set
Nanfang Hospital, Southern Medical University, Guangzhou, Not set
Zhejiang Cancer Hospital, Hangzhou, Not set
Anhui Chest Hospital, Hefei, Not set
The Second Affiliated Hospital of Nanchang University, Jiangxi, Not set
Shandong Cancer Hospital, Jinan, Not set
Jiangxi Chest Hospital, Nanchang, Not set
Nanjing Drum Tower Hospital, Nanjing, Not set
Guangxi Medical University Cancer Hospital, Nanning, Not set
Shanghai Chest Hospital, Shanghai, Not set
Shanghai East Hospital, Shanghai, Not set
Shanghai Pulmonary Hospital, Shanghai, Not set
Cancer Hospital of Shantou University Medical College, Shantou, Not set
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Not set
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Not set
Tongji Hospital Tongji Medical College of Hust, Wuhan, Not set
The First Affiliated Hospital of Xian Jiaotong University, Xi'an, Not set
The First Affiliated Hospital of Xinxiang Medical College, Xinxiang, Not set
Henan Cancer Hospital, Zhengzhou, Not set
Ambroise-Pare Hospital, Assistance Publique - Hopitaux de Paris, Boulogne-Billancourt, Not set
CHU de Caen, Caen, Not set
Clinique Victor Hugo, Centre de Cancerologie de la Sarthe, Le Mans, Not set
Hopital Nord, Marseille, Not set
Institut de Cancer de Montpellier (ICM) - Val d'Aurelle, Montpellier, Not set
Centre Antoine Lacassagne, Nice, Not set
Institut de cancerologie de l'ouest (ICO), Saint-Herblain, Not set
Hopital d'Instruction des Armees (HIA) Begin, Saint-Mandé, Not set
Centre Hospitalier de Saint-Quentin, Saint-Quentin, Not set
Institut de Cancerologie Strasbourg Europe (ICANS), Strasbourg, Not set
Hôpital Foch, Suresnes, Not set
CHI de Toulon la Seyne-sur-Mer Hopital Sainte Musse, Toulon cedex, Not set
Augusta-Kranken-Anstalt gGmbh Klinik für Hämatologie Onkologie und Palliativmedizin, Bochum, Not set
Klinikum Chemnitz gGmbH, Chemnitz, Not set
Universitatsklinikum Essen / Westdeutsches Tumorzentrum, Innere Klinik (Tumorforschung), Essen, Not set
Universitätsklinikum Freiburg, Klinik für Innere Medizin I Hämatologie, Onkologie und Stammzelltransplantation, Freiburg, Not set
LungenClinic Grosshansdorf, Grosshansdorf, Not set
Krankenhaus Martha-Maria Halle Dölau, Halle, Not set
Asklepios Kliniken Hamburg, Hamburg, Not set
Katholisches Marienkrankenhaus gGmbH, Hamburg, Not set
Lungenklinik Hemer, Zentrum fur Pneumologie and Thoraxchirurgie, Hemer, Not set
Vincentius-Diakonissen-Kliniken gAG, St. Vincentius-Kliniken, Medizinische Klinik 2, Karlsruhe, Not set
Klinikum Kassel, Kassel, Not set
Kliniken der Stadt Köln ggmbh, Krankenhaus Koln-Merheim/Lungenklinik, Köln, Not set
Universitatsklinikum Schleswig-Holstein, Lubeck, Not set
Johannes Wesling Klinikum Minden, Minden, Not set
Munchen Klinik Bogenhausen, Klinik fur Pneumologie und Pneumologische Onkologie, Munchen, Not set
Sana Klinikum Offenbach GmbH, Medizinische Klinik IV, Hämatologie und Internistische Onkologie, Offenbach, Not set
Queen Elizabeth Hospital, Hong Kong, Not set
Queen Mary Hospital, Hong Kong, Not set
Prince of Wales Hospital, New Territories, Not set
Soroka University Medical Center, Itzchak Rager Blvd., Beer Seva, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Oncology Institute, Galilee Medical Center, Route 89 Nahariya-Cabri, Nahariya, Not set
Rabin Medical Center, Petah Tiqva, Not set
Kaplan Medical Center, Rehovot, Not set
Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set
Azienda Ospedaliera San Giuseppe Moscati, Avellino, Not set
IRCCS Fondazoine del Piemonte per l'Oncologia, Candiolo, Not set
Azienda Socio Sanitaria Territoriale di Cremona, Cremona, Not set
Ospedale Policlinico San Martino, Genova, Not set
Ospedale San Raffaele, Milano, Not set
Azienda Ospedaliero Universitaria di Modena, Modena, Not set
AORN Cardarelli, Naples, Not set
Azienda Ospedaliera dei Colli, Napoli, Not set
IRCCS Policlinico S. Matteo, Dipartimento Oncologia Ematologia-Oncologia Medica, Pavia, Not set
Azienda Sanitaria Territoriale Pesaro e Urbino (AST), Pesaro, Not set
Ospedale Guglielmo da Saliceto AUSL di Piacenza, Piacenza, Not set
Centro di Riferimento Oncologico, Pordenone, Not set
Regina Elena Institute for Cancer Research, Rome, Not set
ASST Bergamo Ovest- ospedale di Treviglio, Treviglio, Not set
National Cancer Center Hospital East, Chiba, Not set
National Hospital Organization Shikoku Cancer Center, Ehime, Not set
Kyushu University Hospital, Fukuoka, Not set
Kurume University Hospital, Fukuoka, Not set
National Hospital Organization Himeji Medical Center, Hyogo, Not set
Hyogo Cancer Center, Hyogo, Not set
Kanazawa University Hospital, Ishikawa, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Sendai Kousei Hospital, Miyagi, Not set
Niigata Cancer Center Hospital, Niigata, Not set
Osaka Metropolitan University Hospital, Osaka, Not set
Osaka Medical and Pharmaceutical University Hospital, Osaka, Not set
Kindai University Hospital, Osaka, Not set
National Hospital Organization Kinki Chuo Chest Medical Center, Osaka, Not set
Saitama Medical University, Saitama, Not set
SMG - SNU Boramae Medical Center, Dongjak-Gu, Not set
Samsung Medical Center, Gangnam-Gu, Not set
National Cancer Center, Goyang, Not set
Chungbuk National University Hospital, Heungdeok-Gu, Not set
Inha University Hospital, Incheon, Not set
Gachon University Gil Medical Center, Inchon, Not set
Kosin University Gospel Hospital, Seo-gu, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
Ajou University Hospital, Suwon-si, Not set
The Catholic University of Korea, Saint Vincent's Hospital, Suwon, Not set
Health Pharma Professional Research S.A. de C.V., Mexico, Not set
Hospital Universitario Dr. Jose Eleuterio Gonzalez, Mitras Centro, Not set
Oaxaca Site Management Organization, Oaxaca, Not set
Centro de Investigacion Clinica de Oaxaca, Oaxaca, Not set
Clinical Medical Research SC., Orizaba Centro, Not set
Clinica Integral Internacional de Oncologia S de RL de CV, Puebla, Not set
FAICIC Clínical Research, Veracruz, Not set
Amphia Ziekenhuis, Breda, Not set
Ziekenhuis Gelderse Vallei, Ede, Not set
Universitair Medisch Centrum Groningen, Groningen, Not set
Ziekenhuis St Jansdal, Harderwijk, Not set
TweeSteden Ziekenhuis, Tilburg, Not set
Hospital Prof. Doutor Fernando Fonseca, Amadora, Not set
Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, Not set
Fundacao Champalimaud, Lisboa, Not set
Centro Hospitalar Universitário Lisboa Norte - Hospital Pulido Valente, Lisboa, Not set
Hospital Beatriz Angelo. Hospital de Loures., Lisbon, Not set
Centro Hospitalar Universitario Sao Joao, EPE, Porto, Not set
Unidade Local de Saude de Matosinhos EPE - Hospital Pedro Hispano SA, Senhora da Hora, Not set
Raffles Hospital, Singapore, Not set
Tang Tock Seng Hospital, Singapore, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital de la Santa Creu i de Sant Pau, Barcelona, Not set
Hospital Universitari Dexeus (USP Institut Universitari Dexeus/Hospital Universitari Quiron Dexeus), Barcelona, Not set
Hospital Universitari Vall D'Hebron, Barcelona, Not set
Hospital Parc Tauli, Barcelona, Not set
Hospital Universitario Reina Sofia, Cordoba, Not set
Hospital Doctor Josep Trueta, Girona, Not set
Hospital Universitario de Jaen, Jaen, Not set
Hospital Universitario de Canarias, Las Palmas de G.C., Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Clinica Universidad de Navarra, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda, Not set
Hospital Sant Joan de Reus, Reus, Not set
Hospital Regional Universitario de Malaga, Rincon de la Victoria, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitario Virgen del Rocio, Seville, Not set
Instituto Valenciano De Oncologia (IVO), Valencia, Not set
Hospital Universitari i Politecnic La Fe, Valencia, Not set
Hospital Vithas Valencia 9 de Octubre, Valencia, Not set
Changhua Christian Hospital, Changhua City, Not set
E-DA Hospital, Kaohsiung City, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
Chang Gung Memorial Hospital Kaohsiung, Kaohsiung, Not set
National Cheng Kung University Hospital, Tainan, Not set
Chi Mei Hospital, Liouying, Tainan, Not set
National Taiwan University Hospital, Taipei City, Not set
Taipei Veterans General Hospital, Taipei, Not set
Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation, Taoyuan City, Not set
Ankara Bilkent Sehir Hastanesi, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi, Ankara, Not set
Trakya University Faculty of Medicine, Edirne, Not set
Istanbul University Cerrahpasa Medical Faculty Hospital, Fatih, Not set
Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi, Istanbul, Not set
Medipol Mega University Hospital, Istanbul, Not set
Acibadem Mehmet Ali Aydinlar Universitesi Atakent Hastanesi, Kaakaekmece, Not set
Turgut Ozal Medical Faculty, Malatya, Not set
Colchester General Hospital, Colchester, Not set
St Bartholomew's Hospital, Barts Health NHS Trust, London, Not set
The Christie NHS Foundation Trust, Department of Medical Oncology, Manchester, Not set
University Hospital Southampton Nhs Foundation Trust, Southampton, Not set
Conditions: Non-small Cell Lung Cancer
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Recruiting
BOLD-100 is an intravenously administered sterile solution containing the ruthenium-based small molecule. BOLD-100 has been shown to preferentially decrease the expression of GRP78 in tumour cells and ER stressed cells when compared to normal cells. BOLD-100 will be combined with cytotoxic FOLFOX chemotherapy in this study, with a dose escalation cohort to ensure tolerability and safety, followed by a cohort expansion phase.
BOLD-100 is an intravenously administered sterile solution containing the ruthenium-based small molecule. BOLD-100 has been shown to preferentially decrease the expression of GRP78 in tumour cells and ER stressed cells when compared to normal cells. BOLD-100 will be combined with cytotoxic FOLFOX chemotherapy in this study, with a dose escalation cohort to ensure tolerability and safety, followed by a cohort expansion phase. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/21/2025
Locations: University of California, Los Angeles, Santa Monica, California +13 locations
University of California, Los Angeles, Santa Monica, California
Moffitt Cancer Center, Tampa, Florida
Cross Cancer Institue, Edmonton, Alberta
Juravinski Cancer Centre, Hamilton, Ontario
The Ottawa Hospital Cancer Centre, Ottawa, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Jewish General Hospital, Montreal, Quebec
McGill University Health Centre Glen Site, Montréal, Quebec
St. James Hospital, Dublin, Not set
National Cancer Center, Goyang, Not set
Kangbuk Samsung Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital - Yonsei University, Seoul, Not set
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