There are currently 45 active clinical trials seeking participants for Obsessive-Compulsive Disorder research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Massachusetts.
Study of Dextromethorphan in OCD and Related Disorders
NCT04899687
Recruiting
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/24/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder, Illness Anxiety Disorder, Body Dysmorphic Disorders, Somatic Symptom Disorder
Register for Updates
Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
NCT04641143
Recruiting
The study's purpose is to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/17/2024
Locations: Metropolitan Neuro Behavioral Institute, Chandler, Arizona +84 locations
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder
NCT04693351
Recruiting
The study's purpose its to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/17/2024
Locations: Alea Research, Phoenix, Arizona +110 locations
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Effects of Psilocybin in Obsessive Compulsive Disorder
NCT05546658
Recruiting
This study will test the feasibility, safety, and evidence for efficacy of psilocybin administration in participants with obsessive compulsive disorder (OCD). This will serve as a preliminary proof of concept study for future larger studies aimed to investigate the utility, cognitive mechanisms, and neural correlates of this intervention.
Gender:
All
Ages:
Between 21 years and 70 years
Trial Updated:
04/16/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Obsessive-Compulsive Disorder
Register for Updates
SEEG-Guided DBS for OCD
NCT05623306
Recruiting
This is a multi-site, double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months. The study will be conducted in 3 stages: Stage 1 will consist of SEEG brain mapping and optimization of stimulation parameters. Stage 2 will consist of DBS surgery and further optimization of stimulation parameters. Stage 3 will be randomized, crossover treatment, followed by open label treatment.
Gender:
All
Ages:
Between 22 years and 75 years
Trial Updated:
04/16/2024
Locations: Stanford University, Stanford, California +1 locations
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
NCT04131829
Recruiting
The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/10/2024
Locations: Yale OCD Research Clinic - CMHC/CNRU, 34 Park ST, New Haven, Connecticut
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Neural Mechanisms of Response Inhibition Training for OCRD
NCT05377125
Recruiting
The impaired ability to suppress an inappropriate but pre-potent response (response inhibition; RI) characterizes several debilitating clinical problems, including obsessive-compulsive and related disorders (OCRD) such as obsessive-compulsive disorder, trichotillomania, and skin picking disorder. There is a critical need to develop an effective and durable treatment for OCRDs with demonstrable evidence for improving impaired RI. The purpose of our project is to examine the impact of a novel comp... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/03/2024
Locations: UWM Anxiety Disorders Laboratory, Milwaukee, Wisconsin
Conditions: Obsessive-Compulsive Disorder, Tricholemmoma, Skin-Picking
Register for Updates
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
NCT04548609
Recruiting
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder (OCD).
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
04/01/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Register for Updates
Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder
NCT05964998
Recruiting
This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on patient-reported outcomes. The investigator hypothesize that patients who receive active stimulation will experience greater improvement in OCD symptoms than those who receive sham stimulation.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/18/2024
Locations: Rogers Behavioral Health, Oconomowoc, Wisconsin
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Individually Targeted Neuromodulation for Contamination-based OCD
NCT05048251
Recruiting
Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients regardless of symptom type. In this project, the investigators propose to investigate whether a novel method of transcranial magnetic stimulation specifically reduces contamination/washing symptoms - one of the most common types of OCD.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/14/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
NCT05940324
Recruiting
The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/13/2024
Locations: Department of Psychiatry & Behavioral Sciences, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Interpretation Bias as a Mechanism of Treatment Response in OCD
NCT05224414
Recruiting
This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD). CBM-I is a digital intervention designed to directly manipulate interpretation bias through repeated practice on a training task, thereby inducing cognitive changes in a relatively automatic or implicit manner. Specifically, this study will examine the feasibility, acceptability, and clinical outcomes ass... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Obsessive-Compulsive Disorder
Register for Updates