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Obsessive-Compulsive Disorder Clinical Trials
A listing of 39 Obsessive-Compulsive Disorder clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 39
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There are currently 39 active clinical trials seeking participants for Obsessive-Compulsive Disorder research studies. The states with the highest number of trials for Obsessive-Compulsive Disorder participants are California, Florida, New York and Massachusetts.
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Recruiting
Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe. Extensive behavioral testing will be conducted to determine which behaviors are modulated by stimulating which circuits.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/30/2025
Locations: Acacia Clinics, Sunnyvale, California +1 locations
Conditions: Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
Effects of Repeated Psilocybin Dosing in OCD
Recruiting
This study aims to investigate the effects of repeated dosing of oral psilocybin on obsessive-compulsive disorder (OCD) symptomatology in a randomized, waitlist-controlled design with blinded independent ratings, and assess psychological mechanisms that may mediate psilocybin's therapeutic effects on OCD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/28/2025
Locations: Yale OCD Research Clinic (40 Temple St, 4th Floor), New Haven, Connecticut
Conditions: Obsessive-Compulsive Disorder
Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
Recruiting
The study's purpose is to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/23/2025
Locations: Metropolitan Neuro Behavioral Institute, Chandler, Arizona +95 locations
Conditions: Obsessive-Compulsive Disorder
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
Recruiting
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs). Subjects will be treated in an open-label fashion with Epidiolex for two weeks.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/06/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder
Recruiting
The primary aim of the present study is to examine the efficacy and safety of tolcapone in adults with moderate to severe OCD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/06/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Obsessive-Compulsive Disorder, OCD
ERP Plus Improv Group Therapy for OCD (IMPROVE Study)
Recruiting
The goal of this study is to pilot test a novel group therapy intervention for adults with OCD.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/18/2024
Locations: 401 Quarry, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Recruiting
The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/17/2024
Locations: Department of Psychiatry & Behavioral Sciences, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Neurostimulation Versus Therapy for Problems With Emotions
Recruiting
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC). The secondary aim is to identify key changes in the emotion regulation neural network following the combined intervention versus each of the components alone. The third aim is to explore personalized biomarkers for... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
12/10/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders, OCD, Impulse Control Disorder, Eating Disorders, Emotional Dysfunction, Emotional Instability, Emotional Distress, Emotional Maladjustment, Emotional Impulsivity, Obsessive-Compulsive Disorder, Emotion Dysregulation, Borderline Personality Disorder
Efficacy of Nitrous Oxide in OCD: Pilot Study
Recruiting
This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
Recruiting
This study investigates whether caloric vestibular stimulation can modulate a measure of insight in obsessive-compulsive spectrum disorders.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder, Body Dysmorphic Disorders, Illness Anxiety Disorder
Individualized Neuroimaging Biomarkers for Predicting RTMS Response in OCD
Recruiting
The goal of this clinical trial is to discover brain-based subtypes of Obsessive Compulsive Disorder (OCD) and examine treatment response to two different repetitive transcranial magnetic stimulation (rTMS) targets in the brain: the medial prefrontal cortex (MPFC) and the right prefrontal cortex (rPFC).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/26/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Personalized DBS for OCD Guided by Stereoencephalography Mapping
Recruiting
This is a double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months. The study will be conducted in 3 stages: Stage 1 will consist of SEEG brain mapping and optimization of stimulation parameters. Stage 2 will consist of 4-lead DBS surgery with bilateral IPGs and further optimization of stimulation parameters. Stage 3 will be randomized, crossover treatment, followed by open label trea... Read More
Gender:
ALL
Ages:
Between 22 years and 75 years
Trial Updated:
11/01/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Obsessive-Compulsive Disorder, OCD
1 - 12 of 39