There are currently 45 active clinical trials seeking participants for Obsessive-Compulsive Disorder research studies. The states with the highest number of trials for Autism participants are Florida, California, New York and Massachusetts.
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
Recruiting
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder (OCD).
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
03/20/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder
Recruiting
This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on patient-reported outcomes. The investigator hypothesize that patients who receive active stimulation will experience greater improvement in OCD symptoms than those who receive sham stimulation.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/18/2024
Locations: Rogers Behavioral Health, Oconomowoc, Wisconsin
Conditions: Obsessive-Compulsive Disorder
Individually Targeted Neuromodulation for Contamination-based OCD
Recruiting
Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients regardless of symptom type. In this project, the investigators propose to investigate whether a novel method of transcranial magnetic stimulation specifically reduces contamination/washing symptoms - one of the most common types of OCD.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/14/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Obsessive-Compulsive Disorder
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
Recruiting
The purpose of this study is to understand how ketamine works in the brain to bring about a reduction in OCD symptoms.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/13/2024
Locations: Department of Psychiatry & Behavioral Sciences, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Interpretation Bias as a Mechanism of Treatment Response in OCD
Recruiting
This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD). CBM-I is a digital intervention designed to directly manipulate interpretation bias through repeated practice on a training task, thereby inducing cognitive changes in a relatively automatic or implicit manner. Specifically, this study will examine the feasibility, acceptability, and clinical outcomes ass... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: McLean Hospital, Belmont, Massachusetts
Conditions: Obsessive-Compulsive Disorder
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
Recruiting
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs). Subjects will be treated in an open-label fashion with Epidiolex for two weeks.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/08/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
Recruiting
The study's purpose is to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/23/2024
Locations: Metropolitan Neuro Behavioral Institute, Chandler, Arizona +84 locations
Conditions: Obsessive-Compulsive Disorder
Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder
Recruiting
The study's purpose its to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/23/2024
Locations: Alea Research, Phoenix, Arizona +110 locations
Conditions: Obsessive-Compulsive Disorder
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Recruiting
The purpose of this study is to examine whether youth with OCD who benefit from CBT augmentation to SRI can discontinue their medication without relapse over 24 weeks.
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
02/13/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Cognitive Behavioral Therapy, Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
ERP Plus Improv Group Therapy for OCD (IMPROVE Study)
Recruiting
The goal of this study is to pilot test a novel group therapy intervention for adults with OCD.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: 401 Quarry, Stanford, California
Conditions: Obsessive-Compulsive Disorder
SEEG-Guided DBS for OCD
Recruiting
This is a multi-site, double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months. The study will be conducted in 3 stages: Stage 1 will consist of SEEG brain mapping and optimization of stimulation parameters. Stage 2 will consist of DBS surgery and further optimization of stimulation parameters. Stage 3 will be randomized, crossover treatment, followed by open label treatment.
Gender:
All
Ages:
Between 22 years and 75 years
Trial Updated:
01/30/2024
Locations: University of California, San Francisco, California +2 locations
Conditions: Obsessive-Compulsive Disorder
TMS + Exposure Therapy for Pediatric OCD
Recruiting
The goal of this clinical trial is to compare different forms of transcranial magnetic stimulation (TMS) for improving the outcomes of Exposure with Response Prevention (ERP) in youth and young adults with Obsessive-Compulsive Disorder (OCD). Researchers will compare three groups: ERP with one of two different active ("real") forms of TMS vs. ERP with sham ("fake") TMS. The main questions this study aims to answer are: 1) whether TMS normalizes functioning in brain circuits that contribute to co... Read More
Gender:
All
Ages:
Between 12 years and 21 years
Trial Updated:
01/17/2024
Locations: University of Minnesota, Minneapolis, Minnesota +1 locations
Conditions: Obsessive-Compulsive Disorder