There are currently 580 clinical trials in Denver, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Porter Adventist Hospital, National Jewish Health, Rose Medical Center and Colorado Blood Cancer Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury
NCT05110729
Recruiting
This study aims to assess the quality and life and life satisfaction of pediatric and adolescent gymnasts throughout their musculoskeletal injury recovery.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
04/01/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Musculoskeletal Injury, Quality of Life
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A Study of bbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)
NCT05169489
Recruiting
A Phase 1/2 Study of bbT369, a dual targeting CAR T cell drug product with a gene edit, in Relapsed and/or Refractory B cell Non-Hodgkin's Lymphoma.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: Colorado Blood Cancer Institute, Denver, Colorado
Conditions: Diffuse Large B Cell Lymphoma (DLBCL)
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OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)
NCT04757610
Recruiting
A 2-year, phase 3, multicentre, randomised, parallel-group, sham-controlled, double-masked study. Primary efficacy will be determined at Week 52.
Gender:
All
Ages:
50 years and above
Trial Updated:
03/26/2024
Locations: ShORe Investigational Site, Denver, Colorado
Conditions: Neovascular Age-related Macular Degeneration
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Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial
NCT06080698
Recruiting
The Gram-negative bloodstream infection Oral Antibiotic Therapy trial (The GOAT Trial) is a multi-center, randomized clinical trial that hypothesizes that early transition to oral antibiotic therapy for the treatment of Gram-Negative BloodStream Infection (GN-BSI) is as effective but safer than remaining on intravenous (IV) antibiotic therapy for the duration of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: Denver Health Hospital Authority, Denver, Colorado
Conditions: Gram-negative Bacteremia
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Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)
NCT02968212
Recruiting
The purpose of this study is to evaluate the clinical effectiveness and safety of clofazimine when used to treat Mycobacteria avium complex (MAC) lung disease. Funding Source - FDA OOPD
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: National Jewish Health, Denver, Colorado
Conditions: Mycobacterium Avium Complex
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Optimizing Tracheal Intubation Outcomes and Neonatal Safety
NCT05838690
Recruiting
The purpose of the study is to assess the impact of a personalized intubation planning tool, the Personalized INtubation Safety (PINS) Bundle on intubation procedural safety and clinical outcomes among patients intubated in the neonatal intensive care unit (NICU) setting.
Gender:
All
Ages:
1 year and below
Trial Updated:
03/25/2024
Locations: University of Colorado - Denver, Denver, Colorado
Conditions: Infant, Intubation Complication
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Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
NCT05887492
Recruiting
The goal of this interventional clinical trial is to learn about TNG260, a CoREST inhibitor, in combination with pembrolizumab in patients with advanced solid tumors with a known STK11 mutation. The main question[s] it aims to answer are: the recommended dose for Phase 2 to evaluate the safety and tolerability of the combination therapy to determine the pharmacokinetics of TNG260 to evaluate the initial antineoplastic activity Participants will receive study treatment until they experience an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: SCRI at HealthOne, Denver, Colorado
Conditions: Non Small Cell Lung Cancer, Solid Tumors, Adult, Endometrial Cancer, Pancreatic Cancer, Cervical Cancer, Breast Cancer, Carcinoma of Unknown Primary
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Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease
NCT03672630
Recruiting
NTM therapy consists of a multi-drug macrolide based regimen for 18-24 months. Treated patients frequently experience debilitating side effects, and many patients delay the start of antibiotic treatment due to these risks. Common side effects include nausea, diarrhea, and fatigue, and rare but serious toxicities include ocular toxicity, hearing loss, and hematologic toxicity. To date, most of the evidence underlying the current treatment recommendations has come from observational studies in whi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: National Jewish Health, Denver, Colorado
Conditions: Mycobacterium Avium Complex, Nontuberculous Mycobacterium Infection
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SPIROMICS Study of Early COPD Progression (SOURCE)
NCT05033990
Recruiting
This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: To use CT scan imaging to identify which smokers will develop COPD. To identify biomarkers predictive of smokers that will develop COPD. To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD. Procedures (methods): All participants will undergo study related qu... Read More
Gender:
All
Ages:
Between 30 years and 55 years
Trial Updated:
03/25/2024
Locations: National Jewish Health, Denver, Colorado
Conditions: COPD, Early-Onset
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Study of PYX-201 in Solid Tumors
NCT05720117
Recruiting
The primary objective of this study is to determine the recommended dose(s) of PYX-201 for participants with relapsed/refractory (R/R) solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2024
Locations: SCRI - HealthOne Denver, Denver, Colorado
Conditions: Solid Tumor, Advanced Solid Tumor
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Testing the Engaged Approach to Lung Cancer Screening
NCT06327074
Recruiting
The goal of this study is to assess feasibility and acceptability of the Engaged Approach to Lung Cancer Screening (EA-LCS) in diverse lung cancer screening (LCS) programs operating in a variety of geographic regions across Colorado and the US.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2024
Locations: University of Colorado Hospital, Denver, Colorado
Conditions: Lung Cancer
Register for Updates
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis
NCT04102371
Recruiting
The objectives of this multicenter pragmatic clinical trial are to compare the effectiveness and relative safety of balanced fluid resuscitation versus 0.9% "normal" saline in children with septic shock, including whether balanced fluid resuscitation can reduce progression of kidney injury.
Gender:
All
Ages:
Between 2 months and 17 years
Trial Updated:
03/20/2024
Locations: Children's Colorado: University of Colorado, Denver, Colorado
Conditions: Shock, Septic
Register for Updates