There are currently 537 clinical trials in Denver, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Colorado Blood Cancer Institute, National Jewish Health, Rose Medical Center and Porter Adventist Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Swelling Management After Knee Replacement
NCT06095401
Recruiting
To determine if inelastic adjustable compression garment results in improved surgical limb swelling control (bioimpedance assessment - primary outcome) after TKA compared to control (TED hose).
Gender:
ALL
Ages:
Between 50 years and 120 years
Trial Updated:
05/22/2024
Locations: Colorado Joint Replacement, Denver, Colorado
Conditions: Arthroplasties, Knee Replacement
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Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block
NCT04559425
Recruiting
Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally slow heart rate due to maternal antibody-mediated heart disease in the unborn baby (fetus). Since the late seventies, it has been possible to detect and monitor fetal disease by ultrasound images and to treat selected conditions with pharma... Read More
Gender:
FEMALE
Ages:
Between 16 years and 50 years
Trial Updated:
05/21/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Heart Block Complete, Heart Block Second Degree
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Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
NCT05726903
Recruiting
Recommendations regarding contraceptive counseling and reproductive health differ amongst transgender and gender diverse (TGD) youth compared to cis-gender youth. Limited existing literature demonstrates the need for contraceptive counseling that moves beyond cis- and heteronormative assumptions that start with pregnancy prevention and address concerns at the intersection of gender identity. The Investigator's qualitative study will focus on creating best practices regarding equitable contracep... Read More
Gender:
FEMALE
Ages:
Between 15 years and 21 years
Trial Updated:
05/09/2024
Locations: Comprehensive Women's Health Center, Denver, Colorado
Conditions: Gender Dysphoria, Adolescent
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Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start
NCT05444582
Recruiting
This is a prospective clinical research study to test the effectiveness of the Levonorgestrel (LNG) 52 mg Intrauterine Device (IUD) for emergency contraception (EC) and same-day start use that will enroll people receiving care at Planned Parenthood affiliates across the U.S. Our prior work demonstrated efficacy (shows that it works in an ideal setting) for the LNG 52 mg IUD for these uses and this study will test effectiveness (how well it works in the real world) in a larger, heterogenous popul... Read More
Gender:
FEMALE
Ages:
Between 16 years and 35 years
Trial Updated:
05/06/2024
Locations: Planned Parenthood of the Rocky Mountains, Denver, Colorado
Conditions: Contraception
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AETOS Shoulder System
NCT06319911
Recruiting
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Western Orthopaedics, Denver, Colorado
Conditions: Shoulder Osteoarthritis, Shoulder Arthritis
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A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
NCT06399393
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Colorado Blood Cancer Institute, Denver, Colorado
Conditions: Multiple Myeloma
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Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
NCT02090140
Recruiting
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/24/2024
Locations: UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, Colorado
Conditions: Degenerative Lesion of Articular Cartilage of Knee
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The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
NCT03014401
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: 1. Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. 2. Standard arthroscopic treatment (above) without cell transplant.
Gender:
ALL
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, Colorado
Conditions: Knee Osteoarthritis
Register for Updates
Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
NCT01656603
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: Presbyterian / St. Luke's Medical Center, Denver, Colorado
Conditions: Infusion Reactions
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The Crnic Institute Human Trisome Project Biobank
NCT02864108
Recruiting
The Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank will provide de-identified samples to research.
Gender:
ALL
Ages:
Between 6 months and 89 years
Trial Updated:
04/01/2024
Locations: Linda Crnic Institute for Down Syndrome at the University of Colorado Denver, Denver, Colorado
Conditions: Down Syndrome, Trisomy 21
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Quality of Life and Life Satisfaction in Pediatric and Adolescent Gymnasts Through Injury
NCT05110729
Recruiting
This study aims to assess the quality and life and life satisfaction of pediatric and adolescent gymnasts throughout their musculoskeletal injury recovery.
Gender:
ALL
Ages:
Between 8 years and 18 years
Trial Updated:
04/01/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Musculoskeletal Injury, Quality of Life
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A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT06322693
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Denver, Colorado +1 locations
Conditions: Neoplasms
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