There are currently 133 active clinical trials seeking participants for Autism Spectrum Disorder research studies. The states with the highest number of trials for Autism Spectrum Disorder participants are California, New York, Ohio and Massachusetts.
A Center Based Early Intervention Program for Preschoolers with Developmental Disorders
Recruiting
The purpose of this study is to examine the effectiveness of a 12-week early intervention program that will include 12 weekly hours in an intensive center-based preschool environment or in the home to treat social communication deficits in children with developmental disorders. The study will include children with developmental disorders, such as Autism Spectrum Disorder, neurogenetic disorders, or intellectual disability.
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
10/07/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Development Disorder, Child, Developmental Disability, Development Delay, Autism Spectrum Disorder
Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children with Autism
Recruiting
Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions. The goal of this pilot investigation is to apply a biologically-based approach to identify predictors of treatment response in children with ASD who are receiving Pivotal Response Treatment (PRT), an evidence-based behavioral intervention. Specifically, the investigators propose to identify neuroimaging biomarkers of treatment response to a PRT program (PRT-... Read More
Gender:
ALL
Ages:
Between 2 years and 4 years
Trial Updated:
10/07/2024
Locations: Stanford University, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
Trial of Center-Based Vs. In-Home Pivotal Response Treatment (PRT) in Autism
Recruiting
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young children with autism spectrum disorder (ASD) with significant language delay. The two groups will also be compared to a control group that consists of children who are receiving treatment as usual (TAU).
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
10/07/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism, Autism Spectrum Disorder, ASD
Melatonin and Sleep Spindles in Autism
Recruiting
Sleep disturbances and sensory sensitivities are common disabling features of autism, but their underlying causes are not clear. We hypothesize that both of these difficulties reflect disrupted communication between a deep brain structure, the thalamus, and the brain's outer layer, the cortex. This communication is mediated by the thalamic reticular nucleus (TRN). Due to its small size and location deep in the brain, we cannot assess TRN function without invasive techniques. Fortunately, sleep s... Read More
Gender:
ALL
Ages:
Between 12 years and 18 years
Trial Updated:
09/30/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Autism Spectrum Disorder
School-based Paraeducator Education for Engagement At Recess
Recruiting
The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize paraeducators' use (fidelity and sustainment) of an evidence-based social engagement intervention, Remaking Recess (RR). RR aims to improve peer related social skills for autistic students and their non-autistic peers who are socially isolated or peripheral and need support during recess.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
09/16/2024
Locations: University of California Los Angeles, Los Angeles, California +2 locations
Conditions: Autism Spectrum Disorder, Neurodevelopmental Disorders
Pilot Trial of the RUBI Program for Autistic Adults
Recruiting
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI intervention feasible and acceptable for autistic adults and their families? * Does the redesigned RUBI intervention reduce challenging behaviors and enhance the quality of life for autistic adults? * Rese... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Els for Autism Foundation, Jupiter, Florida +2 locations
Conditions: Autism Spectrum Disorder, Behavior, Parenting
Development and Evaluation of A Game-Based Mobile App for Increasing Physical Activity in Autistic Adults
Recruiting
The clinical study aims to develop and test a gamified mobile health app called PuzzleWalk (PW) to promote physical activity (PA) and reduce sedentary behavior (SB) in autistic adults, including those with mild intellectual disabilities (ID). The study addresses the need for tailored interventions in this population, who are at higher risk for lifestyle-related chronic health conditions due to lower PA and higher SB. The upgraded version of PuzzleWalk integrates behavior change techniques and ga... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/29/2024
Locations: Carpenter Sports Building, Newark, Delaware +1 locations
Conditions: Autism Spectrum Disorder
In-Person Mindfulness-based Intervention for Adolescents with Autism Spectrum Disorder and Their Caregivers
Recruiting
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve co-occurring mental health symptoms.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
08/28/2024
Locations: Southwest Autism Research and Resource Center, Phoenix, Arizona
Conditions: Autism Spectrum Disorder, Autism
Telehealth-Enabled Versus In-Person Parent-Mediated Behavioral Treatment for Challenging Behaviors in Children With ASD
Recruiting
The purpose of the research is to determine whether parent-mediated behavior therapy for challenging behavior commonly displayed by children with autism spectrum disorder (ASD) can be as effective when delivered via telehealth as when delivered in-person.
Gender:
ALL
Ages:
Between 2 years and 7 years
Trial Updated:
08/23/2024
Locations: Stanford University, Stanford, California +1 locations
Conditions: Autism Spectrum Disorder
Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)
Recruiting
This trial aims to study the efficacy and safety of cannabidivarin (CBDV) in children with ASD.
Gender:
ALL
Ages:
Between 5 years and 18 years
Trial Updated:
08/20/2024
Locations: Montefiore Medical Center, Bronx, New York +1 locations
Conditions: Autism Spectrum Disorder
Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With Autism Spectrum Disorder
Recruiting
Study ITI-007-035 is a Phase 1b, multicenter, open-label study to evaluate the safety, tolerability, and PK of lumateperone for pediatric patients with Autism Spectrum Disorder.
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
08/14/2024
Locations: Clinical Site 6, Miami, Florida +7 locations
Conditions: Autism Spectrum Disorder
STEPS Implementation Trial
Recruiting
This study will inform understanding of how to support emerging adults with autism spectrum disorder (ASD). The investigators will use a theoretically informed and research-based transition support program developed for people with ASD and test how effective it is when delivered by community agencies. Results will provide information on the effectiveness of the program as well as on mechanisms of change and contextual factors that promote or impede implementation.
Gender:
ALL
Ages:
Between 16 years and 25 years
Trial Updated:
08/14/2024
Locations: Center o=for Youth Development and Intervention, Tuscaloosa, Alabama
Conditions: Autism Spectrum Disorder